{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T11:41:36Z","timestamp":1771674096697,"version":"3.50.1"},"reference-count":24,"publisher":"Codon Publications","issue":"1","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Allergologia et Immunopathologia"],"published-print":{"date-parts":[[2015,1]]},"DOI":"10.1016\/j.aller.2013.11.002","type":"journal-article","created":{"date-parts":[[2014,6,2]],"date-time":"2014-06-02T14:07:03Z","timestamp":1401718023000},"page":"14-18","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":31,"title":["A human monoclonal anti-TNF alpha antibody (adalimumab) reduces airway inflammation and ameliorates lung histology in a murine model of acute asthma"],"prefix":"10.15586","volume":"43","author":[{"given":"F.","family":"Catal","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Mete","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Tayman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Topal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Albayrak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Sert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"6228","reference":[{"key":"10.1016\/j.aller.2013.11.002_bib0005","unstructured":"(GINA) 2011. Available from: http:\/\/www.ginasthma.org"},{"key":"10.1016\/j.aller.2013.11.002_bib0010","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0091-6749(93)90029-F","article-title":"Pathology of asthma","volume":"92","author":"Hogg","year":"1993","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.aller.2013.11.002_bib0015","doi-asserted-by":"crossref","first-page":"5411","DOI":"10.4049\/jimmunol.154.10.5411","article-title":"TNF-alpha mediates recruitment of neutrophils and eosinophils during airway inflammation","volume":"154","author":"Lukacs","year":"1995","journal-title":"J Immunol"},{"key":"10.1016\/j.aller.2013.11.002_bib0020","doi-asserted-by":"crossref","first-page":"1972","DOI":"10.1164\/ajrccm.155.6.9196104","article-title":"TNF mediates lung leak, but not neutrophil accumulation, in lungs of rats given IL-1 intratracheally","volume":"155","author":"Hybertson","year":"1997","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.aller.2013.11.002_bib0025","doi-asserted-by":"crossref","first-page":"1786","DOI":"10.4049\/jimmunol.138.6.1786","article-title":"Immunoregulatory activity of recombinant human tumor necrosis factor (TNF)-alpha: induction of TNF receptors on human T cells and TNFalpha-mediated enhancement of T cell responses","volume":"138","author":"Scheurich","year":"1987","journal-title":"J Immunol"},{"key":"10.1016\/j.aller.2013.11.002_bib0030","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1165\/ajrcmb.15.1.8679220","article-title":"TNF alpha is important in human lung allergic reactions","volume":"15","author":"Casale","year":"1996","journal-title":"Am J Respir Cell Mol Biol"},{"key":"10.1016\/j.aller.2013.11.002_bib0035","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1111\/j.1365-2249.2007.03509.x","article-title":"Tumour necrosis factor-alpha blockade suppresses murine allergic airways inflammation","volume":"151","author":"Hutchison","year":"2008","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.aller.2013.11.002_bib0040","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1111\/j.1365-2222.2005.02407.x","article-title":"Anti-tumor necrosis factor-alpha antibody treatment reduces pulmonary inflammation and methacholine hyper-responsiveness in a murine asthma model induced by house dust","volume":"36","author":"Kim","year":"2006","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.aller.2013.11.002_bib0045","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1016\/j.cellbi.2005.07.002","article-title":"FITC-induced murine pulmonary inflammation: CC10 up-regulation and concurrent Shh expression","volume":"29","author":"Fisher","year":"2005","journal-title":"Cell Biol Int"},{"key":"10.1016\/j.aller.2013.11.002_bib0050","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1172\/JCI200317265","article-title":"Beta-arrestin-2 regulates the development of allergic asthma","volume":"112","author":"Walker","year":"2003","journal-title":"J Clin Invest"},{"key":"10.1016\/j.aller.2013.11.002_bib0055","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1165\/ajrcmb.20.4.3508","article-title":"Th1- and Th2-type cytokines regulate the expression and production of eotaxin and RANTES by human lung fibroblasts","volume":"20","author":"Teran","year":"1999","journal-title":"Am J Respir Cell Mol Biol"},{"key":"10.1016\/j.aller.2013.11.002_bib0060","doi-asserted-by":"crossref","first-page":"5613","DOI":"10.4049\/jimmunol.157.12.5613","article-title":"Human monocyte chemoattractant protein (MCP)-4 is a novel CC chemokine with activities on monocytes, eosinophils, and basophils induced in allergic and nonallergic inflammation that signals through the CC chemokine receptors (CCR)-2 and -3","volume":"157","author":"Garcia-Zepeda","year":"1996","journal-title":"J Immunol"},{"key":"10.1016\/j.aller.2013.11.002_bib0065","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1165\/ajrcmb.10.5.8179909","article-title":"Interleukin-4, -5, and -6 and tumor necrosis factor-alpha in normal and asthmatic airways: evidence for the humanmast cell as a source of these cytokines","volume":"10","author":"Bradding","year":"1994","journal-title":"Am J Respir Cell Mol Biol"},{"key":"10.1016\/j.aller.2013.11.002_bib0070","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1016\/S0091-6749(99)70079-5","article-title":"Human eosinophils release matrix metalloproteinase-9 on stimulation with TNF alpha","volume":"104","author":"Schwingshackl","year":"1999","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.aller.2013.11.002_bib0075","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1136\/thx.2005.045260","article-title":"Tumour necrosis factor (TNF alpha) as a novel therapeutic target in symptomatic corticosteroid dependent asthma","volume":"60","author":"Howarth","year":"2005","journal-title":"Thorax"},{"key":"10.1016\/j.aller.2013.11.002_bib0080","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1053\/j.gastro.2005.11.030","article-title":"Human antitumor necrosis factor monoclonal antibody (adalimumab) in Crohn's disease: the CLASSIC-I trial","volume":"130","author":"Hanauer","year":"2006","journal-title":"Gastroenterology"},{"key":"10.1016\/j.aller.2013.11.002_bib0085","doi-asserted-by":"crossref","first-page":"2644","DOI":"10.1172\/JCI117966","article-title":"Interleukin-10 inhibits antigen-induced cellular recruitment into the airways of sensitized mice","volume":"95","author":"Zuany-Amorim","year":"1995","journal-title":"J Clin Invest"},{"key":"10.1016\/j.aller.2013.11.002_bib0090","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1016\/S0022-3565(25)20671-1","article-title":"Pharmacological evidence for tumor necrosis factor as a mediator of allergic inflammation in the airways","volume":"278","author":"Renzetti","year":"1996","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1016\/j.aller.2013.11.002_bib0095","doi-asserted-by":"crossref","first-page":"1681","DOI":"10.1002\/art.1780361206","article-title":"Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to tumor necrosis factor alpha","volume":"36","author":"Elliott","year":"1993","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.aller.2013.11.002_bib0100","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1152\/ajplung.2000.279.6.L1047","article-title":"Modulation of allergic inflammation in mice deficient in TNF receptors","volume":"279","author":"Rudmann","year":"2000","journal-title":"Am J Physiol-Lung Cell Mol Physiol"},{"key":"10.1016\/j.aller.2013.11.002_bib0105","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1165\/ajrcmb.16.3.9070618","article-title":"Development of airway hyperresponsiveness is dependent on interferon-gamma and independent of eosinophil infiltration","volume":"16","author":"Hessel","year":"1997","journal-title":"Am J Respir Cell Mol Biol"},{"key":"10.1016\/j.aller.2013.11.002_bib0110","doi-asserted-by":"crossref","first-page":"569","DOI":"10.3349\/ymj.2009.50.4.569","article-title":"The soluble tumor necrosis factor-alpha receptor suppresses airway inflammation in a murine model of acute asthma","volume":"50","author":"Nam","year":"2009","journal-title":"Yonsei Med J"},{"key":"10.1016\/j.aller.2013.11.002_bib0115","doi-asserted-by":"crossref","first-page":"4126","DOI":"10.1016\/S0041-1345(98)01365-7","article-title":"Anti-TNF alpha therapy is useful in rheumatoid arthritis and Crohn's disease: analysis of the mechanism of action predicts utility in other diseases","volume":"30","author":"Feldman","year":"1998","journal-title":"Transplant Proc"},{"key":"10.1016\/j.aller.2013.11.002_bib0120","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1056\/NEJMoa050580","article-title":"Evidence of a role of tumor necrosis factor alpha in refractory asthma","volume":"354","author":"Berry","year":"2006","journal-title":"N Engl J Med"}],"container-title":["Allergologia et Immunopathologia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301054614000172?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301054614000172?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,5,3]],"date-time":"2025-05-03T05:58:54Z","timestamp":1746251934000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0301054614000172"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,1]]},"references-count":24,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015,1]]}},"alternative-id":["S0301054614000172"],"URL":"https:\/\/doi.org\/10.1016\/j.aller.2013.11.002","relation":{},"ISSN":["0301-0546"],"issn-type":[{"value":"0301-0546","type":"print"}],"subject":[],"published":{"date-parts":[[2015,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A human monoclonal anti-TNF alpha antibody (adalimumab) reduces airway inflammation and ameliorates lung histology in a murine model of acute asthma","name":"articletitle","label":"Article Title"},{"value":"Allergologia et Immunopathologia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.aller.2013.11.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 SEICAP. Published by Elsevier Espa\u00f1a, S.L. All rights reserved.","name":"copyright","label":"Copyright"}]}}