{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T00:33:21Z","timestamp":1772757201159,"version":"3.50.1"},"reference-count":48,"publisher":"Codon Publications","issue":"6","license":[{"start":{"date-parts":[[2017,11,1]],"date-time":"2017-11-01T00:00:00Z","timestamp":1509494400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Allergologia et Immunopathologia"],"published-print":{"date-parts":[[2017,11]]},"DOI":"10.1016\/j.aller.2016.08.010","type":"journal-article","created":{"date-parts":[[2016,11,17]],"date-time":"2016-11-17T05:17:02Z","timestamp":1479359822000},"page":"573-578","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":22,"title":["Cofactors and comorbidities in patients with aspirin\/NSAID hypersensitivity"],"prefix":"10.15586","volume":"45","author":[{"given":"M.","family":"S\u00e1nchez-Borges","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Caballero-Fonseca","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Capriles-Hulett","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"6228","reference":[{"key":"10.1016\/j.aller.2016.08.010_bib0245","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1111\/j.1398-9995.1980.tb01730.x","article-title":"Aspirin intolerance and recurrent urticaria in normal adults and children","volume":"35","author":"Settipane","year":"1980","journal-title":"Allergy"},{"key":"10.1016\/j.aller.2016.08.010_bib0250","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1111\/all.12260","article-title":"Classification and practical approach to the diagnosis and management of hypersensitivity to nonsteroidal anti-inflammatory drugs","volume":"68","author":"Kowalski","year":"2013","journal-title":"Allergy"},{"key":"10.1016\/j.aller.2016.08.010_bib0255","doi-asserted-by":"crossref","first-page":"298","DOI":"10.4168\/aair.2016.8.4.298","article-title":"Update on the management of aspirin-exacerbated respiratory disease","volume":"8","author":"Buchheit","year":"2016","journal-title":"Allergy Asthma Immunol Res"},{"key":"10.1016\/j.aller.2016.08.010_bib0260","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1016\/S1081-1206(10)62084-4","article-title":"The natural history and clinical characteristics of aspirin-exacerbated respiratory disease","volume":"89","author":"Berges-Gimeno","year":"2002","journal-title":"Ann Allergy Asthma Immunol"},{"key":"10.1016\/j.aller.2016.08.010_bib0265","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1111\/jdv.12658","article-title":"Aspirin-exacerbated cutaneous disease (AECD) is a distinct subphenotype of chronic spontaneous urticaria","volume":"9","author":"S\u00e1nchez-Borges","year":"2015","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"10.1016\/j.aller.2016.08.010_bib0270","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1111\/all.12313","article-title":"The EAACI\/GA2LEN\/EDF\/WAO Guideline for the definition, classification, diagnosis, and management of urticaria: the 2013 revision and update","volume":"69","author":"Zuberbier","year":"2014","journal-title":"Allergy"},{"key":"10.1016\/j.aller.2016.08.010_bib0275","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/S1081-1206(10)62748-2","article-title":"Atopy is a risk factor for nonsteroidal anti-inflammatory drug sensitivity","volume":"84","author":"S\u00e1nchez-Borges","year":"2000","journal-title":"Ann Allergy"},{"key":"10.1016\/j.aller.2016.08.010_bib0280","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/S1081-1206(10)62226-0","article-title":"Tolerability to new COX-2 Inhibitors in NSAID-sensitive patients with cutaneous reactions","volume":"87","author":"S\u00e1nchez-Borges","year":"2001","journal-title":"Ann Allergy Asthma Immunol"},{"key":"10.1016\/j.aller.2016.08.010_bib0285","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/S1081-1206(10)61282-3","article-title":"Tolerance of nonsteroidal anti-inflammatory drug-sensitive patients to the highly specific cyclooxygenase-2 inhibitors","volume":"94","author":"S\u00e1nchez-Borges","year":"2005","journal-title":"Ann Allergy Asthma Immunol"},{"key":"10.1016\/j.aller.2016.08.010_bib0290","series-title":"NSAIDs: a profile of adverse effects","first-page":"157","article-title":"Allergic and pseudoallergic reactions associated with nonsteroidal anti-inflammatory drugs","author":"Hoigne","year":"1992"},{"key":"10.1016\/j.aller.2016.08.010_bib0295","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1016\/S0091-6749(96)70102-1","article-title":"Intolerance to nonsteroidal antiinflammatory drugs: results of controlled drug challenges in 98 patients","volume":"98","author":"Quiralte","year":"1996","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.aller.2016.08.010_bib0300","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1590\/S0104-42302000000300003","article-title":"Clinical findings of sensitivity to analgesics and nonsteroidal antiinflammatory drugs","volume":"46","author":"Ros\u00e1rio","year":"2000","journal-title":"Rev Assoc Med Bras"},{"key":"10.1016\/j.aller.2016.08.010_bib0305","first-page":"277","article-title":"NSAID facial angioedema in a selected pediatric atopic population","volume":"10","author":"Capriles-Behrens","year":"2000","journal-title":"J Investig Allergol Clin Immunol"},{"key":"10.1016\/j.aller.2016.08.010_bib0310","first-page":"139","article-title":"Increased total and mite-specific IgE in patients with aspirin-induced urticaria and angioedema","volume":"20","author":"S\u00e1nchez-Borges","year":"2010","journal-title":"J Investig Allergol Clin Immunol"},{"key":"10.1016\/j.aller.2016.08.010_bib0315","first-page":"194","article-title":"Comparison of clinical characteristics and prognosis of chronic urticaria according to the aspirin sensitivity","volume":"25","author":"Ye","year":"2005","journal-title":"J Asthma Allergy Clin Immunol"},{"key":"10.1016\/j.aller.2016.08.010_bib0320","series-title":"Anaphylaxis. Principles and practice","first-page":"163","article-title":"Non steroidal anti-inflammatory drug-induced anaphylaxis","author":"S\u00e1nchez-Borges","year":"2013"},{"key":"10.1016\/j.aller.2016.08.010_bib0325","doi-asserted-by":"crossref","first-page":"97","DOI":"10.2332\/allergolint.C-07-53","article-title":"Food-dependent exercise-induced anaphylaxis, (FDEIA), Food-dependent exercise-induced anaphylaxis induced by low dose aspirin therapy","volume":"57","author":"Fujii","year":"2008","journal-title":"Allergol Int"},{"key":"10.1016\/j.aller.2016.08.010_bib0330","first-page":"351","article-title":"Drugs as risk factors of food anaphylaxis in adults: a case-control study","volume":"193","author":"Moneret-Vautrin","year":"2009","journal-title":"Bull Acad Natl Med"},{"key":"10.1016\/j.aller.2016.08.010_bib0335","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1111\/j.1398-9995.2012.02799.x","article-title":"Anaphylaxis to pork kidney is related to IgE antibodies specific for galactose-alpha-1,3-galactose","volume":"67","author":"Moisset","year":"2012","journal-title":"Allergy"},{"key":"10.1016\/j.aller.2016.08.010_bib0340","first-page":"3","article-title":"Possible interaction among hypersensitivity to lipid transfer proteins, chronic urticaria, and hypersensitivity reactions to nonsteroidal anti-inflammatory drugs","volume":"43","author":"Romano","year":"2011","journal-title":"Eur Ann Allergy Clin Immunol"},{"key":"10.1016\/j.aller.2016.08.010_bib0345","doi-asserted-by":"crossref","first-page":"1643","DOI":"10.1111\/cea.12011","article-title":"Lipid transfer proteins: the most frequent sensitizer in Italian subjects with food-dependent exercise-induced anaphylaxis","volume":"42","author":"Romano","year":"2012","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.aller.2016.08.010_bib0350","first-page":"19","article-title":"Hypersensitivity to lipid transfer protein is frequently associated with chronic urticaria","volume":"43","author":"Asero","year":"2011","journal-title":"Eur Ann Allergy Clin Immunol"},{"key":"10.1016\/j.aller.2016.08.010_bib0355","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1007\/s11882-010-0128-9","article-title":"The role of lipid transfer proteins in allergic diseases","volume":"10","author":"Egger","year":"2010","journal-title":"Curr Allergy Asthma Rep"},{"key":"10.1016\/j.aller.2016.08.010_bib0360","doi-asserted-by":"crossref","first-page":"1529","DOI":"10.1111\/j.1365-2222.2012.04071.x","article-title":"Lipid transfer protein syndrome: clinical pattern, cofactor effect and profile of molecular sensitization to plant-foods and pollens","volume":"42","author":"Pascal","year":"2012","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.aller.2016.08.010_bib0365","doi-asserted-by":"crossref","first-page":"1316","DOI":"10.1111\/j.1398-9995.2012.02877.x.","article-title":"Co-factor-enhanced food allergy","volume":"67","author":"Cardona","year":"2012","journal-title":"Allergy"},{"key":"10.1016\/j.aller.2016.08.010_bib0370","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1046\/j.1365-2133.2002.04601.x","article-title":"Food-dependent exercise-induced anaphylaxis: influence of concurrent aspirin administration on skin testing and provocation","volume":"146","author":"Aihara","year":"2002","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.aller.2016.08.010_bib0375","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1111\/j.1365-2230.2009.03709.x","article-title":"Two cases of wheat-dependent anaphylaxis induced by aspirin administration but not by exercise","volume":"35","author":"Matsukura","year":"2009","journal-title":"Clin Exp Dermatol"},{"key":"10.1016\/j.aller.2016.08.010_bib0380","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1046\/j.1365-2133.2001.04329.x","article-title":"Aspirin enhances the induction of type I allergic symptoms when combined with food and exercise in patients with food-dependent exercise-induced anaphylaxis","volume":"145","author":"Harada","year":"2001","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.aller.2016.08.010_bib0385","doi-asserted-by":"crossref","first-page":"229","DOI":"10.2332\/allergolint.12-OA-0495","article-title":"Serum gliadin monitoring extracts patients with false negative results in challenge tests for the diagnosis of wheat-dependent exercise-induced anaphylaxis","volume":"62","author":"Kohno","year":"2013","journal-title":"Allergol Int"},{"key":"10.1016\/j.aller.2016.08.010_bib0390","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaci.2014.08.024","article-title":"Using a gluten oral food challenge protocol to improve diagnosis of wheat-dependent exercise-induced anaphylaxis","volume":"135","author":"Brockow","year":"2015","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.aller.2016.08.010_bib0395","doi-asserted-by":"crossref","first-page":"2075","DOI":"10.1152\/jappl.2001.90.6.2075","article-title":"Gastrointestinal permeability during exercise: effects of aspirin and energy-containing beverages","volume":"90","author":"Lambert","year":"2001","journal-title":"J Appl Physiol"},{"key":"10.1016\/j.aller.2016.08.010_bib0400","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1111\/j.1365-2222.2005.02213.x","article-title":"Exercise and aspirin increase levels of circulating gliadin peptides in patients with wheat-dependent exercise-induced anaphylaxis","volume":"35","author":"Matsuo","year":"2005","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.aller.2016.08.010_bib0405","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/0091-6749(80)90136-0","article-title":"Augmentation of allergic histamine release from human leukocytes by nonsteroidal anti-inflammatory analgesic agents","volume":"66","author":"Wojnar","year":"1980","journal-title":"J Allergy Clin Immunol"},{"issue":"Suppl. 1","key":"10.1016\/j.aller.2016.08.010_bib0410","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1159\/000232888","article-title":"Control mechanisms of histamine release from human basophils in vitro: the role of phospholipase A2 and of lipoxygenase metabolites","volume":"66","author":"Marone","year":"1981","journal-title":"Int Arch Allergy Appl Immunol"},{"key":"10.1016\/j.aller.2016.08.010_bib0415","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.jaci.2015.05.042","article-title":"Distinct transcriptome profiles differentiate nonsteroidal anti-inflammatory drug-dependent from nonsteroidal anti-inflammatory drug-independent food-induced anaphylaxis","volume":"137","author":"Mu\u00f1oz-Cano Pascal","year":"2016","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.aller.2016.08.010_bib0420","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1016\/j.iac.2006.08.001","article-title":"Angiotensin-converting enzyme inhibitor-associated angioedema","volume":"26","author":"Byrd","year":"2006","journal-title":"Immunol Allergy Clin N Am"},{"key":"10.1016\/j.aller.2016.08.010_bib0425","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1288\/00005537-199203000-00005","article-title":"Angioedema: 5 years\u2019 experience, with a review of the disorder's presentation and treatment","volume":"102","author":"Megerian","year":"1992","journal-title":"Laryngoscope"},{"key":"10.1016\/j.aller.2016.08.010_bib0430","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1016\/0735-6757(93)90166-9","article-title":"Angioedema in the emergency department: the impact of angiotensin-converting enzyme inhibitors","volume":"11","author":"Pigman","year":"1993","journal-title":"Am J Emerg Med"},{"key":"10.1016\/j.aller.2016.08.010_bib0435","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1177\/000348940111000801","article-title":"Changing trends in angioedema","volume":"110","author":"Cohen","year":"2001","journal-title":"Ann Otol Rhinol Laryngol"},{"key":"10.1016\/j.aller.2016.08.010_bib0440","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1111\/j.1365-2222.2009.03323.x","article-title":"Angiotensin converting enzyme inhibitor induced angio-oedema: a review of the pathophysiology and risk factors","volume":"40","author":"Hoover","year":"2010","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.aller.2016.08.010_bib0445","doi-asserted-by":"crossref","first-page":"441","DOI":"10.2332\/allergolint.C-08-61","article-title":"Recurrent severe angioedema associated with imidapril and diclofenac","volume":"57","author":"Kampitak","year":"2008","journal-title":"Allergol Int"},{"key":"10.1016\/j.aller.2016.08.010_bib0450","doi-asserted-by":"crossref","first-page":"195","DOI":"10.4168\/aair.2010.2.3.195","article-title":"Angiotensin-converting enzyme inhibitors and angioedema","volume":"2","author":"S\u00e1nchez-Borges","year":"2010","journal-title":"Allergy Asthma Immunol Res"},{"key":"10.1016\/j.aller.2016.08.010_bib0455","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1097\/ACI.0000000000000175","article-title":"Hidden allergens and oral mite anaphylaxis: the pancake syndrome revisited","volume":"15","author":"S\u00e1nchez-Borges","year":"2015","journal-title":"Curr Opin Allergy Immunol"},{"key":"10.1016\/j.aller.2016.08.010_bib0460","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.jaci.2012.09.026","article-title":"Anaphylaxis from ingestion of mites: pancake anaphylaxis","volume":"131","author":"S\u00e1nchez-Borges","year":"2013","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.aller.2016.08.010_bib0465","first-page":"311","article-title":"A new triad: sensitivity to aspirin, allergic rhinitis, and severe allergic reaction to ingested aeroallergens","volume":"59","author":"S\u00e1nchez-Borges","year":"1997","journal-title":"Cutis"},{"key":"10.1016\/j.aller.2016.08.010_bib0470","doi-asserted-by":"crossref","first-page":"e25","DOI":"10.2500\/ar.2012.3.0025","article-title":"Mite-induced inflammation: more than allergy","volume":"3","author":"S\u00e1nchez-Borges","year":"2012","journal-title":"Allergy Rhinol"},{"key":"10.1016\/j.aller.2016.08.010_bib0475","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1016\/j.jaip.2016.04.011","article-title":"Aspirin or nonsteroidal anti-inflammatory drug-exacerbated chronic rhinosinusitis","volume":"4","author":"Ledford","year":"2016","journal-title":"J Allergy Clin Immunol Pract"},{"key":"10.1016\/j.aller.2016.08.010_bib0480","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1007\/s11882-015-0552-y","article-title":"Hypersensitivity to aspirin and other NSAIDs: diagnostic approach in patients with chronic rhinosinusitis","volume":"15","author":"Makowska","year":"2015","journal-title":"Curr Allergy Asthma Rep"}],"container-title":["Allergologia et Immunopathologia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301054616301215?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301054616301215?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,6,20]],"date-time":"2024-06-20T17:08:22Z","timestamp":1718903302000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0301054616301215"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11]]},"references-count":48,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2017,11]]}},"alternative-id":["S0301054616301215"],"URL":"https:\/\/doi.org\/10.1016\/j.aller.2016.08.010","relation":{},"ISSN":["0301-0546"],"issn-type":[{"value":"0301-0546","type":"print"}],"subject":[],"published":{"date-parts":[[2017,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cofactors and comorbidities in patients with aspirin\/NSAID hypersensitivity","name":"articletitle","label":"Article Title"},{"value":"Allergologia et Immunopathologia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.aller.2016.08.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 SEICAP. Published by Elsevier Espa\u00f1a, S.L.U. All rights reserved.","name":"copyright","label":"Copyright"}]}}