{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T04:39:59Z","timestamp":1792471199302,"version":"4.5.0"},"reference-count":38,"publisher":"Codon Publications","issue":"6","license":[{"start":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T00:00:00Z","timestamp":1604188800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Allergologia et Immunopathologia"],"published-print":{"date-parts":[[2020,11]]},"DOI":"10.1016\/j.aller.2020.03.007","type":"journal-article","created":{"date-parts":[[2020,5,11]],"date-time":"2020-05-11T00:01:51Z","timestamp":1589155311000},"page":"568-575","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"title":["Predictors of a positive oral food challenge to cow's milk in children sensitized to cow's milk"],"prefix":"10.15586","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5245-9847","authenticated-orcid":false,"given":"R.","family":"Ayats-Vidal","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1610-5168","authenticated-orcid":false,"given":"L.","family":"Valdesoiro-Navarrete","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Garc\u00eda-Gonz\u00e1lez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O.","family":"Asensio-De la Cruz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Larramona-Carrera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Bosque-Garc\u00eda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"6228","reference":[{"key":"10.1016\/j.aller.2020.03.007_bib0195","doi-asserted-by":"crossref","first-page":"1716","DOI":"10.3390\/nu10111716","article-title":"Cow's milk protein allergy in infancy: a risk factor for functional gastrointestinal disorders in children?","volume":"10","author":"Pensabene","year":"2018","journal-title":"Nutrients"},{"key":"10.1016\/j.aller.2020.03.007_bib0200","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S1081-1206(10)62120-5","article-title":"Frequency of cow's milk allergy in childhood","volume":"89","author":"Host","year":"2002","journal-title":"Ann Allergy Asthma Immunol"},{"key":"10.1016\/j.aller.2020.03.007_bib0205","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1111\/cea.12302","article-title":"BSACI guideline for the diagnosis and management of cow's milk allergy","volume":"44","author":"Luyt","year":"2014","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.aller.2020.03.007_bib0210","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1097\/MPG.0b013e31825c9482","article-title":"Diagnostic approach and management of cow's-milk protein allergy in infants and children: ESPGHAN GI Committee practical guidelines","volume":"55","author":"Koletzko","year":"2012","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"10.1016\/j.aller.2020.03.007_bib0215","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.mcna.2005.08.012","article-title":"Adverse reactions to foods","volume":"90","author":"Nowak-Wegrzyn","year":"2006","journal-title":"Med Clin North Am"},{"key":"10.1016\/j.aller.2020.03.007_bib0220","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/j.aller.2015.01.003","article-title":"Position document: IgE-mediated cow's milk allergy","volume":"43","author":"Martorell-Aragon\u00e9s","year":"2015","journal-title":"Allergol Immunopathol (Madr)"},{"key":"10.1016\/j.aller.2020.03.007_bib0225","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.jaci.2010.10.011","article-title":"Diagnosis and Rationale for Action Against Cow's Milk Allergy (DRACMA): a summary report","volume":"126","author":"Fiocchi","year":"2010","journal-title":"J Allergy Clin Imunol"},{"key":"10.1016\/j.aller.2020.03.007_bib0230","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1016\/j.jaip.2016.04.009","article-title":"Food allergy sensitization and presentations in siblings of food allergic children","volume":"4","author":"Gupta","year":"2016","journal-title":"J Allergy Clin Immunol Pract"},{"key":"10.1016\/j.aller.2020.03.007_bib0235","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1111\/all.12333","article-title":"The diagnosis of food allergy: a systematic review and meta-analysis","volume":"69","author":"Soares-Weiser","year":"2014","journal-title":"Allergy"},{"key":"10.1016\/j.aller.2020.03.007_bib0240","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1111\/pai.12066","article-title":"Testing children for allergies: why, how, who and when. An updated statement of the European Academy of Allergy and Clinical immunology (EAACI) Section on Pediatrics and the EAACI-Clemens von Piquet Foundation","author":"Eigenmann","year":"2013","journal-title":"Pediatr Allergy Immunol"},{"key":"10.1016\/j.aller.2020.03.007_bib0245","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1016\/S0091-6749(97)70133-7","article-title":"Relationship between food-specific IgE concentration and the risk of positive food challenge in children and adolescents","volume":"100","author":"Sampson","year":"1997","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.aller.2020.03.007_bib0250","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1067\/mai.2001.114708","article-title":"Utility of food-specific IgE concentrations in predicting symptomatic food allergy","volume":"107","author":"Sampson","year":"2001","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.aller.2020.03.007_bib0255","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/j.aller.2018.10.006","article-title":"Predictive value of the number of adverse reaction episodes for the IgE-mediated food allergy diagnosis","volume":"47","author":"Miceli Sopo","year":"2019","journal-title":"Allergol Immunopathol"},{"key":"10.1016\/j.aller.2020.03.007_bib0260","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/S0301-0546(08)75864-6","article-title":"The predictive value of specific immunoglobulin E levels in serum for the outcome of the development of tolerance in cow's milk allergy","volume":"36","author":"Martorell","year":"2008","journal-title":"Allergol Immunopathol"},{"key":"10.1016\/j.aller.2020.03.007_bib0265","first-page":"185","article-title":"Specific IgE levels in the infant","volume":"107","author":"Garcia-Ara","year":"2001","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.aller.2020.03.007_bib0270","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1111\/j.1365-2222.2005.02150.x","article-title":"The predictive value of specific immunoglobulin E levels in serum for the outcome of oral food challenges","volume":"35","author":"Celik-Bilgili","year":"2005","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.aller.2020.03.007_bib0275","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.jaci.2012.06.049","article-title":"Utility of casein-specific IgE levels in predicting reactivity to baked milk","volume":"131","author":"Caubet","year":"2013","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.aller.2020.03.007_bib0280","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.1111\/j.1365-2222.2010.03568.x","article-title":"Performance of a components-based allergen-microarray in the diagnosis of cow's milk and hen's egg allergy","volume":"40","author":"D\u2019Urbano","year":"2010","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.aller.2020.03.007_bib0285","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.aller.2013.09.012","article-title":"Establishing a cut-off for the serum levels of specific IgE to milk and its components for cow's milk allergy: results from a specific population","volume":"43","author":"Castro","year":"2015","journal-title":"Allergol Immunopathol (Madr)"},{"key":"10.1016\/j.aller.2020.03.007_bib0290","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1159\/000486311","article-title":"Predictors of persistent milk allergy in children: a retrospective cohort study","volume":"175","author":"Koike","year":"2018","journal-title":"Int Arch Allergy Immunol"},{"key":"10.1016\/j.aller.2020.03.007_bib0295","article-title":"Blood or skin: what is best predicting cow's milk allergy diagnosis?","author":"Castro","year":"2019","journal-title":"Eur Ann Allergy Clin Immunol"},{"key":"10.1016\/j.aller.2020.03.007_bib0300","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/j.aller.2018.12.007","article-title":"Predicting outgrowth of IgE-mediated cow's milk allergy: diagnostic tests in children under two years of age","volume":"47","author":"Uncuoglu","year":"2019","journal-title":"Allergol Immunopathol (Madr)"},{"key":"10.1016\/j.aller.2020.03.007_bib0305","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1034\/j.1399-3038.13.s.15.7.x","article-title":"Clinical course of cow's milk protein allergy\/intolerance and atopic diseases in childhood","volume":"13","author":"Host","year":"2002","journal-title":"Pediatr Allergy Immunol"},{"key":"10.1016\/j.aller.2020.03.007_bib0310","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.jped.2017.06.022","article-title":"Accuracy of serum IgE concentrations and papule diameter in the diagnosis of cow's milk allergy","volume":"94","author":"Franco","year":"2018","journal-title":"J Pediatr (Rio J)"},{"key":"10.1016\/j.aller.2020.03.007_bib0315","doi-asserted-by":"crossref","first-page":"1540","DOI":"10.1046\/j.1365-2222.2000.00928.x","article-title":"Specificity of allergen skin testing in predicting positive open food challenges to milk, egg and peanut in children","volume":"30","author":"Sporik","year":"2000","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.aller.2020.03.007_bib0320","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.1111\/j.1398-9995.2005.00806.x","article-title":"Utility of the ratio of food-speci\ufb01c IgE\/total IgE in predicting symptomatic food allergy in children","volume":"60","author":"Mehl","year":"2005","journal-title":"Allergy"},{"key":"10.1016\/j.aller.2020.03.007_bib0325","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1111\/pai.12278","article-title":"Can total IgE\/specific IgE ratio predict tolerance in cow's milk allergic children?","volume":"25","author":"Machinena-Spera","year":"2014","journal-title":"Pediatr Allergy Immunol"},{"key":"10.1016\/j.aller.2020.03.007_bib0330","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1186\/s13052-017-0410-8","article-title":"Specific IgE and skin prick tests to diagnose allergy to fresh and baked cow's milk according to age: a systematic review","volume":"43","author":"Coumo","year":"2017","journal-title":"Ital J Pediatr"},{"key":"10.1016\/j.aller.2020.03.007_bib0335","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1007\/BF02914935","article-title":"In vitro assays for immunoglobulin: E. Methodology, indications, and interpretation","volume":"6","author":"Johansson","year":"1988","journal-title":"Clin Rev Allergy"},{"issue":"Suppl.","key":"10.1016\/j.aller.2020.03.007_bib0340","doi-asserted-by":"crossref","first-page":"S365","DOI":"10.1016\/j.jaci.2009.03.042","article-title":"Work Group report: oral food challenge testing. Adverse Reactions to Food Committee of American Academy of Allergy, Asthma & Immunology","volume":"123","author":"Nowak-Wegrzyn","year":"2009","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.aller.2020.03.007_bib0345","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1148\/radiology.143.1.7063747","article-title":"The meaning and use of the area under a receiver operating characteristic curve","volume":"143","author":"Hanley","year":"1982","journal-title":"Radiology"},{"key":"10.1016\/j.aller.2020.03.007_bib0350","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1002\/1097-0142(1950)3:1<32::AID-CNCR2820030106>3.0.CO;2-3","article-title":"Index for rating diagnostic tests","volume":"3","author":"Youden","year":"1950","journal-title":"Cancer"},{"key":"10.1016\/j.aller.2020.03.007_bib0355","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1002\/bimj.200710415","article-title":"Youden Index and optimal cut-point estimated from observations affected by a lower limit of detection","volume":"50","author":"Ruopp","year":"2008","journal-title":"Biom J"},{"key":"10.1016\/j.aller.2020.03.007_bib0360","first-page":"300","article-title":"An overview of cow's milk allergy in children","volume":"139","author":"Benharnou","year":"2009","journal-title":"Swiss Med Wkly"},{"key":"10.1016\/j.aller.2020.03.007_bib0365","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1186\/s40413-017-0162-3","article-title":"Debates in allergy medicine: molecular allergy diagnosis with ISAC will replace screenings by skin prick test in the future","volume":"10","author":"Jensen","year":"2017","journal-title":"World Allergy Organ J"},{"key":"10.1016\/j.aller.2020.03.007_bib0370","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.jaip.2015.07.017","article-title":"Food allergy to uncommonly challenged foods is rare based on oral food challenge","volume":"4","author":"Ram","year":"2016","journal-title":"J Allergy Clin Immunol Pract"},{"key":"10.1016\/j.aller.2020.03.007_bib0375","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1016\/j.jpeds.2010.09.027","article-title":"Oral food challenges in children with a diagnosis of food allergy","volume":"158","author":"Fleischer","year":"2011","journal-title":"J Pediatr"},{"key":"10.1016\/j.aller.2020.03.007_bib0380","doi-asserted-by":"crossref","first-page":"2689","DOI":"10.3389\/fimmu.2018.02689","article-title":"Analysis of a large standardized food challenge data set to determine predictors of positive outcome across multiple allergens","volume":"9","author":"Sindher","year":"2018","journal-title":"Front Immunol"}],"container-title":["Allergologia et Immunopathologia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301054620300677?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301054620300677?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,10,23]],"date-time":"2022-10-23T10:43:40Z","timestamp":1666521820000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0301054620300677"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11]]},"references-count":38,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2020,11]]}},"alternative-id":["S0301054620300677"],"URL":"https:\/\/doi.org\/10.1016\/j.aller.2020.03.007","relation":{},"ISSN":["0301-0546"],"issn-type":[{"value":"0301-0546","type":"print"}],"subject":[],"published":{"date-parts":[[2020,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Predictors of a positive oral food challenge to cow's milk in children sensitized to cow's milk","name":"articletitle","label":"Article Title"},{"value":"Allergologia et Immunopathologia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.aller.2020.03.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 SEICAP. Published by Elsevier Espa\u00f1a, S.L.U. All rights reserved.","name":"copyright","label":"Copyright"}]}}