{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,25]],"date-time":"2025-02-25T05:30:51Z","timestamp":1740461451361,"version":"3.37.3"},"reference-count":44,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82173607"],"award-info":[{"award-number":["82173607"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003453","name":"Guangdong Provincial Natural Science Foundation","doi-asserted-by":"publisher","award":["2024A1515011969"],"award-info":[{"award-number":["2024A1515011969"]}],"id":[{"id":"10.13039\/501100003453","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","ajpm-online.net","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Preventive Medicine"],"published-print":{"date-parts":[[2025,3]]},"DOI":"10.1016\/j.amepre.2024.12.006","type":"journal-article","created":{"date-parts":[[2024,12,8]],"date-time":"2024-12-08T00:05:20Z","timestamp":1733616320000},"page":"588-597","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Variability in Cardiometabolic Parameters and All-Cause and Cause-Specific Mortality in Older Adults: Evidence From 2 Prospective Cohorts"],"prefix":"10.1016","volume":"68","author":[{"given":"Jian-Yun","family":"Lu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rui","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jie-Qiang","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qi","family":"Zhong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi-Ning","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jia-Ru","family":"Hong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ling-Bing","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Da-Xing","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2706-9599","authenticated-orcid":false,"given":"Xian-Bo","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"20","key":"10.1016\/j.amepre.2024.12.006_bib0001","doi-asserted-by":"crossref","first-page":"1506","DOI":"10.1161\/CIRCULATIONAHA.121.057642","article-title":"Associations of dietary cholesterol, serum cholesterol, and egg consumption with overall and cause-specific mortality: systematic review and updated meta-analysis","volume":"145","author":"Zhao","year":"2022","journal-title":"Circulation"},{"key":"10.1016\/j.amepre.2024.12.006_bib0002","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.atherosclerosis.2023.03.012","article-title":"Association of remnant cholesterol with risk of cardiovascular disease events, stroke, and mortality: a systemic review and meta-analysis","volume":"371","author":"Yang","year":"2023","journal-title":"Atherosclerosis"},{"issue":"7","key":"10.1016\/j.amepre.2024.12.006_bib0003","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1001\/jamacardio.2017.1421","article-title":"Systolic blood pressure reduction and risk of cardiovascular disease and mortality: a systematic review and network meta-analysis","volume":"2","author":"Bundy","year":"2017","journal-title":"JAMA Cardiol"},{"issue":"2","key":"10.1016\/j.amepre.2024.12.006_bib0004","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1007\/s00125-020-05319-w","article-title":"Impact of age at type 2 diabetes mellitus diagnosis on mortality and vascular complications: systematic review and meta-analyses","volume":"64","author":"Nanayakkara","year":"2021","journal-title":"Diabetologia"},{"issue":"2","key":"10.1016\/j.amepre.2024.12.006_bib0005","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1007\/s00125-021-05592-3","article-title":"Prediabetes and risk of mortality, diabetes-related complications and comorbidities: umbrella review of meta-analyses of prospective studies","volume":"65","author":"Schlesinger","year":"2022","journal-title":"Diabetologia"},{"issue":"1","key":"10.1016\/j.amepre.2024.12.006_bib0006","doi-asserted-by":"crossref","first-page":"49","DOI":"10.4093\/dmj.2021.0316","article-title":"Association between variability of metabolic risk factors and cardiometabolic outcomes","volume":"46","author":"Park","year":"2022","journal-title":"Diabetes Metab J"},{"issue":"20","key":"10.1016\/j.amepre.2024.12.006_bib0007","doi-asserted-by":"crossref","first-page":"2596","DOI":"10.1016\/j.jacc.2019.02.063","article-title":"Risk factor variability and cardiovascular outcome: JACC review topic of the week","volume":"73","author":"Messerli","year":"2019","journal-title":"J Am Coll Cardiol"},{"issue":"12","key":"10.1016\/j.amepre.2024.12.006_bib0008","doi-asserted-by":"crossref","first-page":"2450","DOI":"10.3390\/nu14122450","article-title":"Lipid variability and risk of cardiovascular diseases and all-cause mortality: a systematic review and meta-analysis of cohort studies","volume":"14","author":"Li","year":"2022","journal-title":"Nutrients"},{"issue":"3","key":"10.1016\/j.amepre.2024.12.006_bib0009","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2024.3062","article-title":"Long-term body mass index variability and adverse cardiovascular outcomes","volume":"7","author":"Almuwaqqat","year":"2024","journal-title":"JAMA Netw Open"},{"issue":"1","key":"10.1016\/j.amepre.2024.12.006_bib0010","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/s12933-022-01735-x","article-title":"Weight variability and cardiovascular outcomes: a systematic review and meta-analysis","volume":"22","author":"Massey","year":"2023","journal-title":"Cardiovasc Diabetol"},{"issue":"2","key":"10.1016\/j.amepre.2024.12.006_bib0011","doi-asserted-by":"crossref","DOI":"10.1016\/j.cpcardiol.2023.102343","article-title":"Long-term systolic blood pressure variability independent of mean blood pressure is associated with mortality and cardiovascular events: A systematic review and meta-analysis","volume":"49","author":"Saputra","year":"2024","journal-title":"Curr Probl Cardiol"},{"issue":"3","key":"10.1016\/j.amepre.2024.12.006_bib0012","doi-asserted-by":"crossref","first-page":"486","DOI":"10.2337\/dc18-1430","article-title":"Visit-to-visit glycemic variability and risks of cardiovascular events and all-cause mortality: the ALLHAT study","volume":"42","author":"Echouffo-Tcheugui","year":"2019","journal-title":"Diabetes Care"},{"issue":"3","key":"10.1016\/j.amepre.2024.12.006_bib0013","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2018-024476","article-title":"Multimorbidity of cardiometabolic diseases: prevalence and risk for mortality from one million Chinese adults in a longitudinal cohort study","volume":"9","author":"Zhang","year":"2019","journal-title":"BMJ Open"},{"issue":"1","key":"10.1016\/j.amepre.2024.12.006_bib0014","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1186\/s12916-021-02126-x","article-title":"Association between cardiometabolic disease multimorbidity and all-cause mortality in 2 million women and men registered in UK general practices","volume":"19","author":"Canoy","year":"2021","journal-title":"BMC Med"},{"issue":"1","key":"10.1016\/j.amepre.2024.12.006_bib0015","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1186\/s12933-023-01858-9","article-title":"Duration-dependent impact of cardiometabolic diseases and multimorbidity on all-cause and cause-specific mortality: a prospective cohort study of 0.5 million participants","volume":"22","author":"Han","year":"2023","journal-title":"Cardiovasc Diabetol"},{"issue":"6","key":"10.1016\/j.amepre.2024.12.006_bib0016","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1093\/gerona\/glac240","article-title":"Clustering of cardiometabolic risk factors and dementia incidence in older adults: a cross-country comparison in England, the United States, and China","volume":"78","author":"Kontari","year":"2023","journal-title":"J Gerontol A Biol Sci Med Sci"},{"issue":"6","key":"10.1016\/j.amepre.2024.12.006_bib0017","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1097\/CM9.0000000000001985","article-title":"Multimorbidity patterns and association with mortality in 0.5 million Chinese adults","volume":"135","author":"Fan","year":"2022","journal-title":"Chin Med J (Engl)"},{"issue":"23","key":"10.1016\/j.amepre.2024.12.006_bib0018","doi-asserted-by":"crossref","first-page":"2627","DOI":"10.1161\/CIRCULATIONAHA.118.034978","article-title":"Associations of variability in blood pressure, glucose and cholesterol concentrations, and body mass index with mortality and cardiovascular outcomes in the general population","volume":"138","author":"Kim","year":"2018","journal-title":"Circulation"},{"issue":"10","key":"10.1016\/j.amepre.2024.12.006_bib0019","doi-asserted-by":"crossref","first-page":"2895","DOI":"10.1016\/j.numecd.2021.07.004","article-title":"Visit-to-visit variability in the measurements of metabolic syndrome components and the risk of all-cause mortality, cardiovascular disease, and arterial stiffness","volume":"31","author":"Wu","year":"2021","journal-title":"Nutr Metab Cardiovasc Dis"},{"issue":"7","key":"10.1016\/j.amepre.2024.12.006_bib0020","doi-asserted-by":"crossref","first-page":"1580","DOI":"10.3390\/nu11071580","article-title":"Comparisons of visceral adiposity index, body shape index, body mass index and waist circumference and their associations with diabetes mellitus in adults","volume":"11","author":"Wei","year":"2019","journal-title":"Nutrients"},{"key":"10.1016\/j.amepre.2024.12.006_bib0021","article-title":"Obesity paradox and aging: visceral Adiposity Index and all-cause mortality in older individuals: a prospective cohort study","volume":"13","author":"Wang","year":"2022","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"4","key":"10.1016\/j.amepre.2024.12.006_bib0022","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1111\/dom.15424","article-title":"Associations between Chinese visceral adiposity index and risks of all-cause and cause-specific mortality: a population-based cohort study","volume":"26","author":"Wu","year":"2024","journal-title":"Diabetes Obes Metab"},{"issue":"2","key":"10.1016\/j.amepre.2024.12.006_bib0023","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1093\/ije\/dyu067","article-title":"Cohort profile: the Health and Retirement Study (HRS)","volume":"43","author":"Sonnega","year":"2014","journal-title":"Int J Epidemiol"},{"issue":"3","key":"10.1016\/j.amepre.2024.12.006_bib0024","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1093\/ije\/dyr020","article-title":"What are the causal effects of breastfeeding on IQ, obesity and blood pressure? Evidence from comparing high-income with middle-income cohorts","volume":"40","author":"Brion","year":"2011","journal-title":"Int J Epidemiol"},{"issue":"5","key":"10.1016\/j.amepre.2024.12.006_bib0025","doi-asserted-by":"crossref","first-page":"1665","DOI":"10.1093\/ije\/dyu104","article-title":"More ways to distinguish real from artefactual associations in observational studies","volume":"43","author":"Au Yeung","year":"2014","journal-title":"Int J Epidemiol"},{"issue":"1","key":"10.1016\/j.amepre.2024.12.006_bib0027","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1186\/s12933-020-01134-0","article-title":"Glucose variability and the risks of stroke, myocardial infarction, and all-cause mortality in individuals with diabetes: retrospective cohort study","volume":"19","author":"Lee","year":"2020","journal-title":"Cardiovasc Diabetol"},{"issue":"1","key":"10.1016\/j.amepre.2024.12.006_bib0028","doi-asserted-by":"crossref","first-page":"134","DOI":"10.2337\/dc18-1396","article-title":"Visit-to-visit variability of hemoglobin A1c in people without diabetes and risk of major adverse cardiovascular events and all-cause mortality","volume":"42","author":"Ghouse","year":"2019","journal-title":"Diabetes Care"},{"issue":"8","key":"10.1016\/j.amepre.2024.12.006_bib0029","doi-asserted-by":"crossref","first-page":"1366","DOI":"10.1007\/s00125-019-4901-6","article-title":"Fasting glucose variability in young adulthood and incident diabetes, cardiovascular disease and all-cause mortality","volume":"62","author":"Bancks","year":"2019","journal-title":"Diabetologia"},{"key":"10.1016\/j.amepre.2024.12.006_bib0030","doi-asserted-by":"crossref","first-page":"i4098","DOI":"10.1136\/bmj.i4098","article-title":"Blood pressure variability and cardiovascular disease: systematic review and meta-analysis","volume":"354","author":"Stevens","year":"2016","journal-title":"BMJ"},{"issue":"2","key":"10.1016\/j.amepre.2024.12.006_bib0031","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1093\/ajh\/hpw106","article-title":"Visit-to-visit blood pressure variability and mortality and cardiovascular outcomes among older adults: the health, aging, and body composition study","volume":"30","author":"Wu","year":"2017","journal-title":"Am J Hypertens"},{"issue":"6","key":"10.1016\/j.amepre.2024.12.006_bib0032","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1093\/ajh\/hpw157","article-title":"Impact of visit-to-visit variability in systolic blood pressure on cardiovascular outcomes in Korean National Health Insurance Service-National sample cohort","volume":"30","author":"Choi","year":"2017","journal-title":"Am J Hypertens"},{"issue":"8","key":"10.1016\/j.amepre.2024.12.006_bib0033","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1038\/s41440-021-00654-w","article-title":"Visit-to-visit variability of blood pressure and cardiovascular events among the working-age population in Japan: findings from the Japan Epidemiology Collaboration on Occupational Health Study","volume":"44","author":"Inoue","year":"2021","journal-title":"Hypertens Res"},{"issue":"1","key":"10.1016\/j.amepre.2024.12.006_bib0034","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1097\/HJH.0000000000001159","article-title":"Visit-to-visit blood pressure variability is a risk factor for all-cause mortality and cardiovascular disease: a systematic review and meta-analysis","volume":"35","author":"Wang","year":"2017","journal-title":"J Hypertens"},{"issue":"3","key":"10.1016\/j.amepre.2024.12.006_bib0035","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1093\/ageing\/afaa231","article-title":"The association of weight change and all-cause mortality in older adults: a systematic review and meta-analysis","volume":"50","author":"Alharbi","year":"2021","journal-title":"Age Ageing"},{"issue":"1","key":"10.1016\/j.amepre.2024.12.006_bib0036","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1007\/s40618-022-01881-9","article-title":"Weight fluctuation, mortality, and cardiovascular disease in adults in 18 years of follow-up: Tehran Lipid and glucose Study","volume":"46","author":"Mehran","year":"2023","journal-title":"J Endocrinol Invest"},{"issue":"12","key":"10.1016\/j.amepre.2024.12.006_bib0037","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.117.006757","article-title":"Visit-to-visit variability of fasting plasma glucose and the risk of cardiovascular disease and all-cause mortality in the general population","volume":"6","author":"Wang","year":"2017","journal-title":"J Am Heart Assoc"},{"issue":"48","key":"10.1016\/j.amepre.2024.12.006_bib0038","doi-asserted-by":"crossref","first-page":"3560","DOI":"10.1093\/eurheartj\/ehx585","article-title":"Cholesterol variability and the risk of mortality, myocardial infarction, and stroke: a nationwide population-based study","volume":"38","author":"Kim","year":"2017","journal-title":"Eur Heart J"},{"issue":"4","key":"10.1016\/j.amepre.2024.12.006_bib0039","doi-asserted-by":"crossref","first-page":"920","DOI":"10.2337\/dc09-1825","article-title":"Visceral Adiposity Index: a reliable indicator of visceral fat function associated with cardiometabolic risk","volume":"33","author":"Amato","year":"2010","journal-title":"Diabetes Care"},{"key":"10.1016\/j.amepre.2024.12.006_bib0040","doi-asserted-by":"crossref","DOI":"10.1016\/j.ebiom.2023.104964","article-title":"Major lipids and lipoprotein levels and risk of blood pressure elevation: a Mendelian Randomisation study","volume":"100","author":"Liu","year":"2024","journal-title":"EBiomedicine"},{"issue":"11","key":"10.1016\/j.amepre.2024.12.006_bib0041","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0112715","article-title":"Positive relationship between serum low-density lipoprotein cholesterol levels and visceral fat in a Chinese nondiabetic population","volume":"9","author":"Luo","year":"2014","journal-title":"PLoS One"},{"issue":"10","key":"10.1016\/j.amepre.2024.12.006_bib0042","doi-asserted-by":"crossref","first-page":"2058","DOI":"10.2337\/dbi20-0031","article-title":"LDL cholesterol and dysglycemia: an intriguing physiological relationship","volume":"69","author":"Merino","year":"2020","journal-title":"Diabetes"},{"key":"10.1016\/j.amepre.2024.12.006_bib0043","doi-asserted-by":"crossref","DOI":"10.3389\/fpubh.2022.951930","article-title":"Low educational status correlates with a high incidence of mortality among hypertensive subjects from Northeast Rural China","volume":"10","author":"Yu","year":"2022","journal-title":"Front Public Health"},{"issue":"3","key":"10.1016\/j.amepre.2024.12.006_bib0044","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2014-006408","article-title":"Socioeconomic status in relation to cardiovascular disease and cause-specific mortality: a comparison of Asian and Australasian populations in a pooled analysis","volume":"5","author":"Woodward","year":"2015","journal-title":"BMJ Open"},{"issue":"4","key":"10.1016\/j.amepre.2024.12.006_bib0045","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1007\/s11886-021-01454-x","article-title":"New insights into the role of visit-to-visit glycemic variability and blood pressure variability in cardiovascular disease risk","volume":"23","author":"Zhou","year":"2021","journal-title":"Curr Cardiol Rep"}],"container-title":["American Journal of Preventive Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0749379724004288?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0749379724004288?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,2,24]],"date-time":"2025-02-24T14:23:11Z","timestamp":1740406991000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0749379724004288"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3]]},"references-count":44,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,3]]}},"alternative-id":["S0749379724004288"],"URL":"https:\/\/doi.org\/10.1016\/j.amepre.2024.12.006","relation":{},"ISSN":["0749-3797"],"issn-type":[{"type":"print","value":"0749-3797"}],"subject":[],"published":{"date-parts":[[2025,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Variability in Cardiometabolic Parameters and All-Cause and Cause-Specific Mortality in Older Adults: Evidence From 2 Prospective Cohorts","name":"articletitle","label":"Article Title"},{"value":"American Journal of Preventive Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.amepre.2024.12.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}