{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T16:31:34Z","timestamp":1786984294478,"version":"build-2736575974"},"reference-count":27,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2011,9,1]],"date-time":"2011-09-01T00:00:00Z","timestamp":1314835200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The American Journal of Cardiology"],"published-print":{"date-parts":[[2011,9]]},"DOI":"10.1016\/j.amjcard.2011.04.019","type":"journal-article","created":{"date-parts":[[2011,8,13]],"date-time":"2011-08-13T11:01:47Z","timestamp":1313233307000},"page":"691-697","source":"Crossref","is-referenced-by-count":10,"title":["Estimating Health and Economic Benefits from Using Prescription Omega-3 Fatty Acids in Patients With Severe Hypertriglyceridemia"],"prefix":"10.1016","volume":"108","author":[{"given":"Stuart","family":"Samuel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Peskin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bhakti","family":"Arondekar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Alperin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan","family":"Johnson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian","family":"Blumenfeld","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Glenda","family":"Stone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Terry A.","family":"Jacobson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.amjcard.2011.04.019_bib1","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1097\/00043798-199710000-00011","article-title":"Safety and efficacy of Omacor in severe hypertriglyceridemia","volume":"4","author":"Harris","year":"1997","journal-title":"J Cardiovasc Risk"},{"key":"10.1016\/j.amjcard.2011.04.019_bib2","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/S0021-9150(98)00301-3","article-title":"Correlation of serum triglyceride and its reduction by omega-3 fatty acids with lipid transfer activity and the neutral lipid compositions of high-density and low-density lipoproteins","volume":"143","author":"Pownall","year":"1999","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.amjcard.2011.04.019_bib4","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/S1532-0464(02)00006-0","article-title":"Archimedes: a new model for simulating health care systems\u2212the mathematical formulation","volume":"35","author":"Schlessinger","year":"2002","journal-title":"J Biomed Inform"},{"issue":"suppl","key":"10.1016\/j.amjcard.2011.04.019_bib5","first-page":"e88","article-title":"Preventing myocardial infarction and stroke with a simplified bundle of cardioprotective medications","volume":"15","author":"Dudl","year":"2009","journal-title":"Am J Manag Care"},{"key":"10.1016\/j.amjcard.2011.04.019_bib6","doi-asserted-by":"crossref","first-page":"324","DOI":"10.4065\/83.3.324","article-title":"Omega-3 fatty acids for cardioprotection","volume":"83","author":"Lee","year":"2008","journal-title":"Mayo Clin Proc"},{"key":"10.1016\/j.amjcard.2011.04.019_bib7","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1136\/pgmj.2008.073338","article-title":"Omega-3 fatty acids: a comprehensive review of their role in health and disease","volume":"85","author":"Yashodhara","year":"2009","journal-title":"Postgrad Med J"},{"key":"10.1016\/j.amjcard.2011.04.019_bib8","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1016\/S0140-6736(10)60445-X","article-title":"Cardiovascular effects of marine omega-3 fatty acids","volume":"376","author":"Saravanan","year":"2010","journal-title":"Lancet"},{"issue":"suppl","key":"10.1016\/j.amjcard.2011.04.019_bib9","doi-asserted-by":"crossref","first-page":"1477S","DOI":"10.1093\/ajcn\/83.6.1477S","article-title":"N-3 fatty acids and cardiovascular disease","volume":"83","author":"Breslow","year":"2006","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.amjcard.2011.04.019_bib10","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/S0140-6736(99)07072-5","article-title":"Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial","volume":"354","year":"1999","journal-title":"Lancet"},{"key":"10.1016\/j.amjcard.2011.04.019_bib11","doi-asserted-by":"crossref","first-page":"1090","DOI":"10.1016\/S0140-6736(07)60527-3","article-title":"Effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients (JELIS): a randomised open-label, blinded endpoint analysis","volume":"369","author":"Yokoyama","year":"2007","journal-title":"Lancet"},{"key":"10.1016\/j.amjcard.2011.04.019_bib12","series-title":"Estimated per capita fish consumption in the United States","year":"2002"},{"key":"10.1016\/j.amjcard.2011.04.019_bib13","doi-asserted-by":"crossref","first-page":"1847","DOI":"10.1016\/j.clinthera.2005.11.004","article-title":"Herb and supplement use in the US adult population","volume":"27","author":"Kennedy","year":"2005","journal-title":"Clin Ther"},{"key":"10.1016\/j.amjcard.2011.04.019_bib14","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1177\/0272989X06290495","article-title":"Preference-based eq-5d index scores for chronic conditions in the United States","volume":"26","author":"Sullivan","year":"2006","journal-title":"Med Decis Mak"},{"key":"10.1016\/j.amjcard.2011.04.019_bib15","doi-asserted-by":"crossref","first-page":"1885","DOI":"10.1001\/jama.296.15.1885","article-title":"Fish intake, contaminants, and human health: evaluating the risks and the benefits","volume":"296","author":"Mozaffarian","year":"2006","journal-title":"JAMA"},{"key":"10.1016\/j.amjcard.2011.04.019_bib16","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/j.amepre.2005.07.001","article-title":"A quantitative analysis of fish consumption and coronary heart disease mortality","volume":"29","author":"K\u00f6nig","year":"2005","journal-title":"Am J Prev Med"},{"key":"10.1016\/j.amjcard.2011.04.019_bib17","doi-asserted-by":"crossref","first-page":"2705","DOI":"10.1161\/01.CIR.0000132503.19410.6B","article-title":"Accumulated evidence on fish consumption and coronary heart disease mortality: A meta-analysis of cohort studies","volume":"109","author":"He","year":"2004","journal-title":"Circulation"},{"key":"10.1016\/j.amjcard.2011.04.019_bib18","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1007\/s11883-008-0078-z","article-title":"Intakes of long-chain omega-3 fatty acid associated with reduced risk for death from coronary heart disease in healthy adults","volume":"10","author":"Harris","year":"2008","journal-title":"Curr Atheroscler Rep"},{"key":"10.1016\/j.amjcard.2011.04.019_bib19","doi-asserted-by":"crossref","first-page":"1538","DOI":"10.1161\/01.STR.0000130856.31468.47","article-title":"Fish consumption and incidence of stroke: a meta-analysis of cohort studies","volume":"35","author":"He","year":"2004","journal-title":"Stroke"},{"key":"10.1016\/j.amjcard.2011.04.019_bib20","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/j.amepre.2005.07.002","article-title":"A quantitative analysis of fish consumption and stroke risk","volume":"29","author":"Bouzan","year":"2005","journal-title":"Am J Prev Med"},{"issue":"suppl","key":"10.1016\/j.amjcard.2011.04.019_bib21","doi-asserted-by":"crossref","first-page":"1483S","DOI":"10.1093\/ajcn\/83.6.1483S","article-title":"Healthy intakes of n-3 and n-6 fatty acids: estimations considering worldwide diversity","volume":"83","author":"Hibbeln","year":"2006","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.amjcard.2011.04.019_bib22","doi-asserted-by":"crossref","first-page":"3130","DOI":"10.1001\/jama.288.24.3130","article-title":"Fish consumption and risk of stroke in men","volume":"288","author":"He","year":"2002","journal-title":"JAMA"},{"key":"10.1016\/j.amjcard.2011.04.019_bib23","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1001\/archinte.165.2.200","article-title":"Fish consumption and stroke risk in elderly individuals: the Cardiovascular Health Study","volume":"165","author":"Mozaffarian","year":"2005","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.amjcard.2011.04.019_bib24","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1017\/PHN2006942","article-title":"Habitual fish consumption and risk of incident stroke: the European Prospective Investigation into Cancer (EPIC)\u2013Norfolk prospective population study","volume":"9","author":"Myint","year":"2006","journal-title":"Public Health Nutr"},{"key":"10.1016\/j.amjcard.2011.04.019_bib25","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1017\/S0007114509274782","article-title":"Fish consumption and the incidence of cerebrovascular disease","volume":"102","author":"Montonen","year":"2009","journal-title":"Br J Nutr"},{"key":"10.1016\/j.amjcard.2011.04.019_bib26","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1016\/j.jacc.2008.06.018","article-title":"Fish, omega-3 polyunsaturated fatty acids, and mortality from cardiovascular diseases in a nationwide community-based cohort of Japanese men and women: the JACC Study","volume":"52","author":"Yamagishi","year":"2008","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.amjcard.2011.04.019_bib27","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1016\/j.amjcard.2010.05.030","article-title":"30-Year trends in serum lipids among United States adults: results from the National Health and Nutrition Examination Surveys II, III, and 1999\u20132006","volume":"106","author":"Cohen","year":"2010","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.amjcard.2011.04.019_bib28","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1001\/archinternmed.2008.599","article-title":"Hypertriglyceridemia and its pharmacologic treatment among US adults","volume":"169","author":"Ford","year":"2009","journal-title":"Arch Intern Med"}],"container-title":["The American Journal of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002914911016031?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002914911016031?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,6,13]],"date-time":"2019-06-13T21:41:26Z","timestamp":1560462086000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002914911016031"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,9]]},"references-count":27,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2011,9]]}},"alternative-id":["S0002914911016031"],"URL":"https:\/\/doi.org\/10.1016\/j.amjcard.2011.04.019","relation":{},"ISSN":["0002-9149"],"issn-type":[{"value":"0002-9149","type":"print"}],"subject":[],"published":{"date-parts":[[2011,9]]}}}