{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T12:32:57Z","timestamp":1788870777735,"version":"build-2803163510"},"reference-count":23,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100015237","name":"Medicines Company","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100015237","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007478","name":"Cardiovascular Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007478","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008497","name":"Boston Scientific Corporation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008497","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["ajconline.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Cardiology"],"published-print":{"date-parts":[[2014,1]]},"DOI":"10.1016\/j.amjcard.2013.08.034","type":"journal-article","created":{"date-parts":[[2013,10,2]],"date-time":"2013-10-02T13:20:08Z","timestamp":1380720008000},"page":"36-43","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":28,"title":["Association Between Intraprocedural Thrombotic Events and Adverse Outcomes After Primary Percutaneous Coronary Intervention for ST-Segment Elevation Myocardial Infarction (a Harmonizing Outcomes With RevasculariZatiON and Stents in Acute Myocardial Infarction [HORIZONS-AMI] Substudy)"],"prefix":"10.1016","volume":"113","author":[{"given":"Ajay J.","family":"Kirtane","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prabhdeep","family":"Sandhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roxana","family":"Mehran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret","family":"McEntegart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ecaterina","family":"Cristea","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sorin J.","family":"Brener","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ke","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Fahy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"G\u00e9n\u00e9reux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey D.","family":"Wessler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregg W.","family":"Stone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.amjcard.2013.08.034_bib1","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1056\/NEJMoa013404","article-title":"Comparison of angioplasty with stenting, with or without abciximab, in acute myocardial infarction","volume":"346","author":"Stone","year":"2002","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.amjcard.2013.08.034_bib2","doi-asserted-by":"crossref","first-page":"S4","DOI":"10.1016\/j.ahj.2006.04.007","article-title":"Insights into the pathophysiology of ST-elevation myocardial infarction","volume":"151","author":"Brener","year":"2006","journal-title":"Am Heart J"},{"key":"10.1016\/j.amjcard.2013.08.034_bib3","doi-asserted-by":"crossref","first-page":"1739","DOI":"10.1016\/j.jacc.2003.07.012","article-title":"Clinical and angiographic correlates and outcomes of suboptimal coronary flow in patients with acute myocardial infarction undergoing primary percutaneous coronary intervention","volume":"42","author":"Mehta","year":"2003","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.amjcard.2013.08.034_bib4","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.1053\/euhj.2001.3035","article-title":"Incidence and clinical significance of distal embolization during primary angioplasty for acute myocardial infarction","volume":"23","author":"Henriques","year":"2002","journal-title":"Eur Heart J"},{"key":"10.1016\/j.amjcard.2013.08.034_bib5","first-page":"960","article-title":"Visible angiographic complications predict short and long-term outcomes in patients with post-procedural creatine-phosphokinase elevation","volume":"76","author":"Fefer","year":"2010","journal-title":"Catheter Cardiovasc Interv"},{"key":"10.1016\/j.amjcard.2013.08.034_bib6","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1016\/j.amjcard.2006.08.054","article-title":"Effect of no-reflow during primary percutaneous coronary intervention for acute myocardial infarction on six-month mortality","volume":"99","author":"Brosh","year":"2007","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.amjcard.2013.08.034_bib7","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1093\/eurheartj\/ehp033","article-title":"Incidence and clinical consequences of distal embolization on the coronary angiogram after percutaneous coronary intervention for ST-elevation myocardial infarction","volume":"30","author":"Fokkema","year":"2009","journal-title":"Eur Heart J"},{"key":"10.1016\/j.amjcard.2013.08.034_bib8","doi-asserted-by":"crossref","first-page":"2383","DOI":"10.1016\/j.jacc.2009.12.054","article-title":"5-Year prognostic value of no-reflow phenomenon after percutaneous coronary intervention in patients with acute myocardial infarction","volume":"55","author":"Ndrepepa","year":"2010","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.amjcard.2013.08.034_bib9","doi-asserted-by":"crossref","first-page":"899","DOI":"10.2169\/internalmedicine.47.0884","article-title":"Predictors and long-term prognostic implications of angiographic slow\/no-flow during percutaneous coronary intervention for acute myocardial infarction","volume":"47","author":"Suenari","year":"2008","journal-title":"Intern Med"},{"key":"10.1016\/j.amjcard.2013.08.034_bib10","doi-asserted-by":"crossref","first-page":"1745","DOI":"10.1016\/j.jacc.2012.02.019","volume":"59","author":"McEntegart","year":"2012","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.amjcard.2013.08.034_bib11","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1016\/j.jcin.2012.05.007","volume":"5","author":"Pride","year":"2012","journal-title":"JACC Cardiovasc Interv"},{"key":"10.1016\/j.amjcard.2013.08.034_bib12","doi-asserted-by":"crossref","first-page":"2218","DOI":"10.1056\/NEJMoa0708191","article-title":"Bivalirudin during primary PCI in acute myocardial infarction","volume":"358","author":"Stone","year":"2008","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.amjcard.2013.08.034_bib13","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.ahj.2008.02.008","article-title":"The Harmonizing Outcomes with RevasculariZatiON and Stents in Acute Myocardial Infarction (HORIZONS-AMI) trial: study design and rationale","volume":"156","author":"Mehran","year":"2008","journal-title":"Am Heart J"},{"key":"10.1016\/j.amjcard.2013.08.034_bib14","doi-asserted-by":"crossref","first-page":"1946","DOI":"10.1056\/NEJMoa0810116","article-title":"Paclitaxel-eluting stents versus bare-metal stents in acute myocardial infarction","volume":"360","author":"Stone","year":"2009","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.amjcard.2013.08.034_bib15","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1161\/01.CIR.93.5.879","article-title":"TIMI frame count: a quantitative method of assessing coronary artery flow","volume":"93","author":"Gibson","year":"1996","journal-title":"Circulation"},{"key":"10.1016\/j.amjcard.2013.08.034_bib16","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1016\/S0735-1097(01)01779-X","article-title":"Impact of normalized myocardial perfusion after successful angioplasty in acute myocardial infarction","volume":"39","author":"Stone","year":"2002","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.amjcard.2013.08.034_bib17","doi-asserted-by":"crossref","first-page":"2344","DOI":"10.1161\/CIRCULATIONAHA.106.685313","article-title":"Clinical end points in coronary stent trials: a case for standardized definitions","volume":"115","author":"Cutlip","year":"2007","journal-title":"Circulation"},{"key":"10.1016\/j.amjcard.2013.08.034_bib18","doi-asserted-by":"crossref","first-page":"2205","DOI":"10.1056\/NEJMoa0706816","article-title":"Facilitated PCI in patients with ST-elevation myocardial infarction","volume":"358","author":"Ellis","year":"2008","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.amjcard.2013.08.034_bib19","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/S0140-6736(06)68148-8","article-title":"Comparison of primary and facilitated percutaneous coronary interventions for ST-elevation myocardial infarction: quantitative review of randomised trials","volume":"367","author":"Keeley","year":"2006","journal-title":"Lancet"},{"key":"10.1016\/j.amjcard.2013.08.034_bib20","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1056\/NEJMoa0706416","article-title":"Thrombus aspiration during primary percutaneous coronary intervention","volume":"358","author":"Svilaas","year":"2008","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.amjcard.2013.08.034_bib21","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/j.jacc.2007.04.059","article-title":"Angiographic stent thrombosis after routine use of drug-eluting stents in ST-segment elevation myocardial infarction: the importance of thrombus burden","volume":"50","author":"Sianos","year":"2007","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.amjcard.2013.08.034_bib22","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1056\/NEJMoa0904327","article-title":"Ticagrelor versus clopidogrel in patients with acute coronary syndromes","volume":"361","author":"Wallentin","year":"2009","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.amjcard.2013.08.034_bib23","doi-asserted-by":"crossref","first-page":"2001","DOI":"10.1056\/NEJMoa0706482","article-title":"Prasugrel versus clopidogrel in patients with acute coronary syndromes","volume":"357","author":"Wiviott","year":"2007","journal-title":"N\u00a0Engl J Med"}],"container-title":["The American Journal of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002914913019188?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002914913019188?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T06:26:22Z","timestamp":1757571982000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002914913019188"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1]]},"references-count":23,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,1]]}},"alternative-id":["S0002914913019188"],"URL":"https:\/\/doi.org\/10.1016\/j.amjcard.2013.08.034","relation":{},"ISSN":["0002-9149"],"issn-type":[{"value":"0002-9149","type":"print"}],"subject":[],"published":{"date-parts":[[2014,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Association Between Intraprocedural Thrombotic Events and Adverse Outcomes After Primary Percutaneous Coronary Intervention for ST-Segment Elevation Myocardial Infarction (a Harmonizing Outcomes With RevasculariZatiON and Stents in Acute Myocardial Infarction [HORIZONS-AMI] Substudy)","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.amjcard.2013.08.034","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}