{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T21:49:18Z","timestamp":1791150558135,"version":"4.1.0"},"reference-count":28,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2014,4,1]],"date-time":"2014-04-01T00:00:00Z","timestamp":1396310400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The American Journal of Cardiology"],"published-print":{"date-parts":[[2014,4]]},"DOI":"10.1016\/j.amjcard.2013.12.033","type":"journal-article","created":{"date-parts":[[2014,1,16]],"date-time":"2014-01-16T05:17:01Z","timestamp":1389849421000},"page":"1240-1245","source":"Crossref","is-referenced-by-count":32,"title":["Relation of Highly Sensitive Cardiac Troponin T in Hypertrophic Cardiomyopathy to Left Ventricular Mass and Cardiovascular Risk"],"prefix":"10.1016","volume":"113","author":[{"given":"Gilbert","family":"Cramer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeannette","family":"Bakker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Gommans","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Brouwer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurice","family":"Kurvers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Fouraux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Freek","family":"Verheugt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcel","family":"Kofflard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.amjcard.2013.12.033_bib1","doi-asserted-by":"crossref","first-page":"2503","DOI":"10.1001\/jama.2010.1768","article-title":"Association of troponin T detected with a highly-sensitive assay and cardiac structure and mortality risk in the general population","volume":"304","author":"de Lemos","year":"2010","journal-title":"JAMA"},{"key":"10.1016\/j.amjcard.2013.12.033_bib2","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1016\/j.cardfail.2010.07.245","article-title":"Serum levels of high-sensitivity troponin T: a novel marker for cardiac remodeling in hypertrophic cardiomyopathy","volume":"16","author":"Moreno","year":"2010","journal-title":"J\u00a0Card Fail"},{"key":"10.1016\/j.amjcard.2013.12.033_bib3","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1136\/heart.89.6.659","article-title":"Measurements of cardiac troponin T in patients with hypertrophic cardiomyopathy","volume":"89","author":"Sato","year":"2003","journal-title":"Heart"},{"key":"10.1016\/j.amjcard.2013.12.033_bib4","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1002\/clc.20622","article-title":"Serum cardiac troponin I is related to increased left ventricular wall thickness, left ventricular dysfunction, and male gender in hypertrophic cardiomyopathy","volume":"33","author":"Kubo","year":"2010","journal-title":"Clin Cardiol"},{"key":"10.1016\/j.amjcard.2013.12.033_bib5","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1016\/j.amjcard.2013.04.060","article-title":"Usefulness of high-sensitivity cardiac troponin T and brain natriuretic peptide as biomarkers of myocardial fibrosis in patients with hypertrophic cardiomyopathy","volume":"112","author":"Kawasaki","year":"2013","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.amjcard.2013.12.033_bib6","article-title":"Prevalence and determinants of elevated high-sensitivity cardiac troponin T in hypertrophic cardiomyopathy","author":"Jenab","year":"2013","journal-title":"J\u00a0Cardiol"},{"key":"10.1016\/j.amjcard.2013.12.033_bib7","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1161\/CIRCULATIONAHA.107.699579","article-title":"General cardiovascular risk profile for use in primary care: the Framingham Heart Study","volume":"117","author":"D'Agostino","year":"2008","journal-title":"Circulation"},{"key":"10.1016\/j.amjcard.2013.12.033_bib8","doi-asserted-by":"crossref","first-page":"e783","DOI":"10.1161\/CIR.0b013e318223e2bd","article-title":"2011 ACCF\/AHA guideline for the diagnosis and treatment of hypertrophic cardiomyopathy: a report of the American College of Cardiology Foundation\/American Heart Association Task Force on Practice Guidelines","volume":"124","author":"Gersh","year":"2011","journal-title":"Circulation"},{"key":"10.1016\/j.amjcard.2013.12.033_bib9","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1161\/hy0302.104674","article-title":"Assessment of left ventricular mass by cardiovascular magnetic resonance","volume":"39","author":"Myerson","year":"2002","journal-title":"Hypertension"},{"key":"10.1016\/j.amjcard.2013.12.033_bib10","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1161\/CIRCULATIONAHA.104.507723","article-title":"Utility of cardiac magnetic resonance imaging in the diagnosis of hypertrophic cardiomyopathy","volume":"112","author":"Rickers","year":"2005","journal-title":"Circulation"},{"key":"10.1016\/j.amjcard.2013.12.033_bib11","doi-asserted-by":"crossref","first-page":"1252","DOI":"10.1016\/j.jacc.2013.03.055","article-title":"Significance of highly-sensitive troponin T in patients with hypertrophic cardiomyopathy","volume":"62","author":"Kubo","year":"2013","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.amjcard.2013.12.033_bib12","doi-asserted-by":"crossref","first-page":"2252","DOI":"10.1093\/eurheartj\/ehn327","article-title":"Prevalence and pathophysiological mechanisms of elevated cardiac troponin I levels in a population-based sample of elderly subjects","volume":"29","author":"Eggers","year":"2008","journal-title":"Eur Heart J"},{"key":"10.1016\/j.amjcard.2013.12.033_bib13","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1161\/CIRCULATIONAHA.110.005264","article-title":"Cardiac troponin T measured by a highly-sensitive assay predicts coronary heart disease, heart failure, and mortality in the Atherosclerosis Risk in Communities Study","volume":"123","author":"Saunders","year":"2011","journal-title":"Circulation"},{"key":"10.1016\/j.amjcard.2013.12.033_bib14","doi-asserted-by":"crossref","first-page":"2811","DOI":"10.1161\/CIRCULATIONAHA.110.009928","article-title":"Sensitive cardiac troponin T assay and the risk of incident cardiovascular disease in women with and without diabetes mellitus: the Women\u2019s Health Study","volume":"123","author":"Everett","year":"2011","journal-title":"Circulation"},{"key":"10.1016\/j.amjcard.2013.12.033_bib15","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.jacc.2012.10.012","article-title":"Biomarkers of chronic cardiac injury and hemodynamic stress identify a malignant phenotype of left ventricular hypertrophy in the general population","volume":"61","author":"Neeland","year":"2013","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.amjcard.2013.12.033_bib16","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1536\/ihj.54.202","article-title":"Usefulness of serum cardiac troponins T and I to predict cardiac molecular changes and cardiac damage in patients with hypertrophic cardiomyopathy","volume":"54","author":"Okamoto","year":"2013","journal-title":"Int Heart J"},{"key":"10.1016\/j.amjcard.2013.12.033_bib17","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/S0002-9149(03)00477-6","article-title":"Troponin-I elevation in patients with increased left ventricular mass","volume":"92","author":"Hamwi","year":"2003","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.amjcard.2013.12.033_bib18","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.amjcard.2011.02.346","article-title":"Prognostic usefulness of circulating high-sensitivity troponin T in aortic stenosis and the relation to echocardiographic indexes of cardiac function and anatomy","volume":"108","author":"R\u00f8sj\u00f8","year":"2011","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.amjcard.2013.12.033_bib19","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1016\/j.ahj.2010.02.036","article-title":"Association between high-sensitivity cardiac troponin T levels and the predicted cardiovascular risk in middle-aged men without overt cardiovascular disease","volume":"159","author":"Otsuka","year":"2010","journal-title":"Am Heart J"},{"key":"10.1016\/j.amjcard.2013.12.033_bib20","first-page":"226","article-title":"High-sensitivity cardiac troponin T in essential hypertension","volume":"58","author":"Sato","year":"2011","journal-title":"J\u00a0Cardiol"},{"key":"10.1016\/j.amjcard.2013.12.033_bib21","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1016\/j.yjmcc.2011.08.028","article-title":"The coronary circulation and blood flow in left ventricular hypertrophy","volume":"52","author":"Camici","year":"2012","journal-title":"J\u00a0Mol Cell Cardiol"},{"key":"10.1016\/j.amjcard.2013.12.033_bib22","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1016\/j.jacc.2009.04.072","article-title":"The case for myocardial ischemia in hypertrophic cardiomyopathy","volume":"54","author":"Maron","year":"2009","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.amjcard.2013.12.033_bib23","doi-asserted-by":"crossref","first-page":"1643","DOI":"10.1056\/NEJMra0902923","article-title":"Inherited cardiomyopathies","volume":"364","author":"Watkins","year":"2011","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.amjcard.2013.12.033_bib24","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1161\/CIRCRESAHA.111.242974","article-title":"Disease pathways and novel therapeutic targets in hypertrophic cardiomyopathy","volume":"109","author":"Ashrafian","year":"2011","journal-title":"Circ Res"},{"key":"10.1016\/j.amjcard.2013.12.033_bib25","doi-asserted-by":"crossref","first-page":"1473","DOI":"10.1161\/CIRCULATIONAHA.108.838672","article-title":"Cardiac myosin binding protein C mutations and hypertrophic cardiomyopathy: haploinsufficiency, deranged phosphorylation and cardiomyocyte dysfunction","volume":"119","author":"Van Dijk","year":"2009","journal-title":"Circulation"},{"key":"10.1016\/j.amjcard.2013.12.033_bib26","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1161\/CIRCRESAHA.111.300436","article-title":"Perturbed length-dependent activation in human hypertrophic cardiomyopathy with missense sarcomeric gene mutations","volume":"112","author":"Sequeira","year":"2013","journal-title":"Circ Res"},{"key":"10.1016\/j.amjcard.2013.12.033_bib27","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1056\/NEJMoa1002659","article-title":"Myocardial fibrosis as an early manifestation of hypertrophic cardiomyopathy","volume":"363","author":"Ho","year":"2010","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.amjcard.2013.12.033_bib28","first-page":"415","article-title":"Troponin I release after exercise in patients with hypertrophic cardiomyopathy and the effect of betablockade","volume":"76","author":"Pop","year":"2006","journal-title":"Arch Cardiol Mex"}],"container-title":["The American Journal of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002914914000599?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002914914000599?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,10,7]],"date-time":"2018-10-07T05:23:32Z","timestamp":1538889812000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002914914000599"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,4]]},"references-count":28,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2014,4]]}},"alternative-id":["S0002914914000599"],"URL":"https:\/\/doi.org\/10.1016\/j.amjcard.2013.12.033","relation":{},"ISSN":["0002-9149"],"issn-type":[{"value":"0002-9149","type":"print"}],"subject":[],"published":{"date-parts":[[2014,4]]}}}