{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T17:38:05Z","timestamp":1760549885729,"version":"3.40.5"},"reference-count":29,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.com.au","clinicalkey.es","clinicalkey.com","ajconline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Cardiology"],"published-print":{"date-parts":[[2016,1]]},"DOI":"10.1016\/j.amjcard.2015.10.037","type":"journal-article","created":{"date-parts":[[2015,11,6]],"date-time":"2015-11-06T10:32:38Z","timestamp":1446805958000},"page":"192-200","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"title":["Impact of Hemoglobin A1c Levels on Residual Platelet Reactivity and Outcomes After Insertion of Coronary Drug-Eluting Stents (from the ADAPT-DES Study)"],"prefix":"10.1016","volume":"117","author":[{"given":"Mikkel M.","family":"Schoos","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George D.","family":"Dangas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5546-262X","authenticated-orcid":false,"given":"Roxana","family":"Mehran","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ajay J.","family":"Kirtane","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claire","family":"Litherland","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Clemmensen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas D.","family":"Stuckey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernhard","family":"Witzenbichler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giora","family":"Weisz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael J.","family":"Rinaldi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Franz-Josef","family":"Neumann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. Christopher","family":"Metzger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timothy D.","family":"Henry","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David A.","family":"Cox","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter L.","family":"Duffy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruce R.","family":"Brodie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5532-0306","authenticated-orcid":false,"suffix":"Jr.","given":"Ernest L.","family":"Mazzaferri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akiko","family":"Maehara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gregg W.","family":"Stone","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.amjcard.2015.10.037_bib1","doi-asserted-by":"crossref","first-page":"525","DOI":"10.2337\/dc08-1865","article-title":"Factors contributing to increased platelet reactivity in people with diabetes","volume":"32","author":"Schneider","year":"2009","journal-title":"Diabetes Care"},{"key":"10.1016\/j.amjcard.2015.10.037_bib2","doi-asserted-by":"crossref","first-page":"2420","DOI":"10.1093\/eurheartj\/ehl275","article-title":"Low response to clopidogrel is associated with cardiovascular outcome after coronary stent implantation","volume":"27","author":"Geisler","year":"2006","journal-title":"Eur Heart J"},{"key":"10.1016\/j.amjcard.2015.10.037_bib3","doi-asserted-by":"crossref","first-page":"1827","DOI":"10.1016\/j.jacc.2005.07.056","article-title":"Clopidogrel effect on platelet reactivity in patients with stent thrombosis: results of the CREST Study","volume":"46","author":"Gurbel","year":"2005","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.amjcard.2015.10.037_bib4","doi-asserted-by":"crossref","first-page":"1742","DOI":"10.1016\/j.jacc.2006.06.065","article-title":"Impact of the degree of peri-interventional platelet inhibition after loading with clopidogrel on early clinical outcome of elective coronary stent placement","volume":"48","author":"Hochholzer","year":"2006","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.amjcard.2015.10.037_bib5","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1161\/CIRCULATIONAHA.111.029165","article-title":"Platelet reactivity and cardiovascular outcomes after percutaneous coronary intervention: a time-dependent analysis of the Gauging Responsiveness with a VerifyNow P2Y12 assay: Impact on Thrombosis and Safety (GRAVITAS) trial","volume":"124","author":"Price","year":"2011","journal-title":"Circulation"},{"key":"10.1016\/j.amjcard.2015.10.037_bib6","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.1016\/j.jacc.2010.03.103","volume":"56","author":"Campo","year":"2010","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.amjcard.2015.10.037_bib7","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.1016\/j.jacc.2008.06.038","volume":"52","author":"Patti","year":"2008","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.amjcard.2015.10.037_bib8","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1161\/CIRCULATIONAHA.108.812636","article-title":"Cardiovascular death and nonfatal myocardial infarction in acute coronary syndrome patients receiving coronary stenting are predicted by residual platelet reactivity to ADP detected by a point-of-care assay: a 12-month follow-up","volume":"119","author":"Marcucci","year":"2009","journal-title":"Circulation"},{"key":"10.1016\/j.amjcard.2015.10.037_bib9","doi-asserted-by":"crossref","first-page":"2348","DOI":"10.1007\/s00125-012-2584-3","article-title":"Relationship between HbA1c levels and risk of cardiovascular adverse outcomes and all-cause mortality in overweight and obese cardiovascular high-risk women and men with type 2 diabetes","volume":"55","author":"Andersson","year":"2012","journal-title":"Diabetologia"},{"key":"10.1016\/j.amjcard.2015.10.037_bib10","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1111\/j.1464-5491.2011.03456.x","article-title":"Association between HbA1c and cardiovascular disease mortality in older Hong Kong Chinese with diabetes","volume":"29","author":"Xu","year":"2012","journal-title":"Diabet Med"},{"key":"10.1016\/j.amjcard.2015.10.037_bib11","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1111\/j.1755-5922.2010.00249.x","article-title":"Clinical predictors of high posttreatment platelet reactivity to clopidogrel in Koreans","volume":"30","author":"Park","year":"2012","journal-title":"Cardiovasc Ther"},{"key":"10.1016\/j.amjcard.2015.10.037_bib12","doi-asserted-by":"crossref","first-page":"1052","DOI":"10.1016\/j.jacc.2008.05.054","article-title":"Elevated plasma fibrinogen and diabetes mellitus are associated with lower inhibition of platelet reactivity with clopidogrel","volume":"52","author":"Ang","year":"2008","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.amjcard.2015.10.037_bib13","doi-asserted-by":"crossref","first-page":"1626","DOI":"10.1161\/CIRCULATIONAHA.108.791061","volume":"118","author":"Wiviott","year":"2008","journal-title":"Circulation"},{"key":"10.1016\/j.amjcard.2015.10.037_bib14","doi-asserted-by":"crossref","first-page":"3006","DOI":"10.1093\/eurheartj\/ehq325","article-title":"Ticagrelor vs. clopidogrel in patients with acute coronary syndromes and diabetes: a substudy from the PLATelet inhibition and patient Outcomes (PLATO) trial","volume":"31","author":"James","year":"2010","journal-title":"Eur Heart J"},{"key":"10.1016\/j.amjcard.2015.10.037_bib15","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1160\/TH13-01-0004","article-title":"Combined and independent impact of diabetes mellitus and chronic kidney disease on residual platelet reactivity","volume":"110","author":"Baber","year":"2013","journal-title":"Thromb Haemost"},{"key":"10.1016\/j.amjcard.2015.10.037_bib16","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1007\/s11239-010-0547-4","article-title":"Lack of correlation between platelet reactivity and glycaemic control in type 2 diabetes mellitus patients treated with aspirin and clopidogrel","volume":"32","author":"Mangiacapra","year":"2011","journal-title":"J\u00a0Thromb Thrombolysis"},{"key":"10.1016\/j.amjcard.2015.10.037_bib17","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.thromres.2014.05.010","article-title":"Effect of intensive glycemic control on platelet reactivity in patients with long-standing uncontrolled diabetes","volume":"134","author":"Singer","year":"2014","journal-title":"Thromb Res"},{"key":"10.1016\/j.amjcard.2015.10.037_bib18","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1016\/S0140-6736(13)61170-8","article-title":"Platelet reactivity and clinical outcomes after coronary artery implantation of drug-eluting stents (ADAPT-DES): a prospective multicentre registry study","volume":"382","author":"Stone","year":"2013","journal-title":"Lancet"},{"key":"10.1016\/j.amjcard.2015.10.037_bib19","doi-asserted-by":"crossref","first-page":"2344","DOI":"10.1161\/CIRCULATIONAHA.106.685313","article-title":"Clinical end points in coronary stent trials: a case for standardized definitions","volume":"115","author":"Cutlip","year":"2007","journal-title":"Circulation"},{"key":"10.1016\/j.amjcard.2015.10.037_bib20","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/S0140-6736(01)05701-4","article-title":"Effects of pretreatment with clopidogrel and aspirin followed by long-term therapy in patients undergoing percutaneous coronary intervention: the PCI-CURE study","volume":"358","author":"Mehta","year":"2001","journal-title":"Lancet"},{"key":"10.1016\/j.amjcard.2015.10.037_bib21","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1093\/eurheartj\/ehq494","article-title":"A\u00a0pharmacodynamic comparison of prasugrel vs. high-dose clopidogrel in patients with type 2 diabetes mellitus and coronary artery disease: results of the Optimizing anti-Platelet Therapy in diabetes MellitUS (OPTIMUS)-3 Trial","volume":"32","author":"Angiolillo","year":"2011","journal-title":"Eur Heart J"},{"key":"10.1016\/j.amjcard.2015.10.037_bib22","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1160\/TH13-05-0384","article-title":"Ticagrelor versus prasugrel in diabetic patients with an acute coronary syndrome. A pharmacodynamic randomised study","volume":"111","author":"Laine","year":"2014","journal-title":"Thromb Haemost"},{"key":"10.1016\/j.amjcard.2015.10.037_bib23","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.amjcard.2013.09.011","article-title":"Impact of obesity and the metabolic syndrome on response to clopidogrel or prasugrel and bleeding risk in patients treated after coronary stenting","volume":"113","author":"Pankert","year":"2014","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.amjcard.2015.10.037_bib24","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1056\/NEJMoa0904327","article-title":"Ticagrelor versus clopidogrel in patients with acute coronary syndromes","volume":"361","author":"Wallentin","year":"2009","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.amjcard.2015.10.037_bib25","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1016\/j.amjcard.2011.04.029","article-title":"Relation of body mass index to on-treatment (clopidogrel\u00a0+ aspirin) platelet reactivity","volume":"108","author":"Gaglia","year":"2011","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.amjcard.2015.10.037_bib26","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1160\/TH10-07-0440","article-title":"Stability of the high on-treatment platelet reactivity phenotype over time in clopidogrel-treated patients","volume":"105","author":"Jaitner","year":"2011","journal-title":"Thromb Haemost"},{"key":"10.1016\/j.amjcard.2015.10.037_bib27","doi-asserted-by":"crossref","first-page":"1945","DOI":"10.1016\/j.jacc.2011.06.059","article-title":"Impact of platelet reactivity on clinical outcomes after percutaneous coronary intervention. A collaborative meta-analysis of individual participant data","volume":"58","author":"Brar","year":"2011","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.amjcard.2015.10.037_bib28","doi-asserted-by":"crossref","first-page":"1936","DOI":"10.1016\/S0140-6736(14)60611-5","article-title":"Effects of intensive glycaemic control on ischaemic heart disease: analysis of data from the randomised, controlled ACCORD trial","volume":"384","author":"Gerstein","year":"2014","journal-title":"Lancet"},{"key":"10.1016\/j.amjcard.2015.10.037_bib29","doi-asserted-by":"crossref","first-page":"2545","DOI":"10.1056\/NEJMoa0802743","article-title":"Effects of intensive glucose lowering in type 2 diabetes","volume":"358","author":"Gerstein","year":"2008","journal-title":"N\u00a0Engl J Med"}],"container-title":["The American Journal of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002914915022018?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002914915022018?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,6,17]],"date-time":"2022-06-17T19:47:27Z","timestamp":1655495247000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002914915022018"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,1]]},"references-count":29,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2016,1]]}},"alternative-id":["S0002914915022018"],"URL":"https:\/\/doi.org\/10.1016\/j.amjcard.2015.10.037","relation":{},"ISSN":["0002-9149"],"issn-type":[{"type":"print","value":"0002-9149"}],"subject":[],"published":{"date-parts":[[2016,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Impact of Hemoglobin A1c Levels on Residual Platelet Reactivity and Outcomes After Insertion of Coronary Drug-Eluting Stents (from the ADAPT-DES Study)","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.amjcard.2015.10.037","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2016 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}