{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T08:06:59Z","timestamp":1791446819867,"version":"4.3.3"},"reference-count":14,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","ajconline.org","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Cardiology"],"published-print":{"date-parts":[[2016,1]]},"DOI":"10.1016\/j.amjcard.2015.10.040","type":"journal-article","created":{"date-parts":[[2015,11,6]],"date-time":"2015-11-06T20:51:15Z","timestamp":1446843075000},"page":"258-263","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"title":["Prognostic Utility of Brain Natriuretic Peptide in Asymptomatic Patients With Significant Mitral Regurgitation and Preserved Left Ventricular Ejection Fraction"],"prefix":"10.1016","volume":"117","author":[{"given":"Amgad","family":"Mentias","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krishna","family":"Patel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harsh","family":"Patel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. Marc","family":"Gillinov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L. Leonardo","family":"Rodriguez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars G.","family":"Svensson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomislav","family":"Mihaljevic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph F.","family":"Sabik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian P.","family":"Griffin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milind Y.","family":"Desai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.amjcard.2015.10.040_bib1","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1016\/S0002-8703(98)70041-9","article-title":"Plasma brain natriuretic peptide as a biochemical marker of high left ventricular end-diastolic pressure in patients with symptomatic left ventricular dysfunction","volume":"135","author":"Maeda","year":"1998","journal-title":"Am Heart J"},{"key":"10.1016\/j.amjcard.2015.10.040_bib2","doi-asserted-by":"crossref","first-page":"1963","DOI":"10.1161\/01.CIR.93.11.1963","article-title":"Plasma brain natriuretic peptide as an indicator of left ventricular systolic function and long-term survival after acute myocardial infarction. Comparison with plasma atrial natriuretic peptide and n-terminal proatrial natriuretic peptide","volume":"93","author":"Omland","year":"1996","journal-title":"Circulation"},{"key":"10.1016\/j.amjcard.2015.10.040_bib3","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1161\/01.CIR.96.2.509","article-title":"Attenuation of compensation of endogenous cardiac natriuretic peptide system in chronic heart failure: prognostic role of plasma brain natriuretic peptide concentration in patients with chronic symptomatic left ventricular dysfunction","volume":"96","author":"Tsutamoto","year":"1997","journal-title":"Circulation"},{"key":"10.1016\/j.amjcard.2015.10.040_bib4","doi-asserted-by":"crossref","first-page":"2391","DOI":"10.1161\/01.CIR.0000164269.80908.9D","article-title":"B-type natriuretic peptide in organic mitral regurgitation: determinants and impact on outcome","volume":"111","author":"Detaint","year":"2005","journal-title":"Circulation"},{"key":"10.1016\/j.amjcard.2015.10.040_bib5","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1093\/eurjhf\/hfq189","article-title":"Prognostic value of serial B-type natriuretic peptide measurement in asymptomatic organic mitral regurgitation","volume":"13","author":"Klaar","year":"2011","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.amjcard.2015.10.040_bib6","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1136\/heartjnl-2011-301128","article-title":"Prognostic importance of brain natriuretic peptide and left ventricular longitudinal function in asymptomatic degenerative mitral regurgitation","volume":"98","author":"Magne","year":"2012","journal-title":"Heart"},{"key":"10.1016\/j.amjcard.2015.10.040_bib7","doi-asserted-by":"crossref","first-page":"1705","DOI":"10.1016\/j.jacc.2011.07.016","article-title":"Prospective validation of the prognostic usefulness of B-type natriuretic peptide in asymptomatic patients with chronic severe aortic regurgitation","volume":"58","author":"Pizarro","year":"2011","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.amjcard.2015.10.040_bib8","doi-asserted-by":"crossref","first-page":"1440","DOI":"10.1016\/j.echo.2005.10.005","volume":"18","author":"Lang","year":"2005","journal-title":"J\u00a0Am Soc Echocardiogr"},{"key":"10.1016\/j.amjcard.2015.10.040_bib9","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1016\/S0894-7317(03)00335-3","article-title":"Recommendations for evaluation of the severity of native valvular regurgitation with two-dimensional and doppler echocardiography","volume":"16","author":"Zoghbi","year":"2003","journal-title":"J\u00a0Am Soc Echocardiogr"},{"key":"10.1016\/j.amjcard.2015.10.040_bib10","doi-asserted-by":"crossref","first-page":"e521","DOI":"10.1161\/CIR.0000000000000031","article-title":"2014 AHA\/ACC guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology\/American Heart Association Task Force on Practice Guidelines","volume":"129","author":"Nishimura","year":"2014","journal-title":"Circulation"},{"key":"10.1016\/j.amjcard.2015.10.040_bib11","doi-asserted-by":"crossref","first-page":"1498","DOI":"10.1016\/j.amjcard.2005.11.085","article-title":"Utility of plasma N-terminal brain natriuretic peptide as a marker of functional capacity in patients with chronic severe mitral regurgitation","volume":"97","author":"Yusoff","year":"2006","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.amjcard.2015.10.040_bib12","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1093\/eurjhf\/hfs003","article-title":"Prevalence and prognosis of heart failure with preserved ejection fraction and elevated N-terminal pro brain natriuretic peptide: a 10-year analysis from the Copenhagen Hospital Heart Failure Study","volume":"14","author":"Carlsen","year":"2012","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.amjcard.2015.10.040_bib13","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1093\/eurheartj\/ehm553","article-title":"Elevated B-type natriuretic peptide despite normal left ventricular function on rest and\u00a0exercise stress echocardiography in mitral regurgitation","volume":"29","author":"Kerr","year":"2008","journal-title":"Eur Heart J"},{"key":"10.1016\/j.amjcard.2015.10.040_bib14","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1016\/S0735-1097(02)02059-4","article-title":"Plasma brain natriuretic peptide concentration: impact of age and gender","volume":"40","author":"Redfield","year":"2002","journal-title":"J\u00a0Am Coll Cardiol"}],"container-title":["The American Journal of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002914915022043?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002914915022043?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,17]],"date-time":"2018-09-17T19:50:08Z","timestamp":1537213808000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002914915022043"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,1]]},"references-count":14,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2016,1]]}},"alternative-id":["S0002914915022043"],"URL":"https:\/\/doi.org\/10.1016\/j.amjcard.2015.10.040","relation":{},"ISSN":["0002-9149"],"issn-type":[{"value":"0002-9149","type":"print"}],"subject":[],"published":{"date-parts":[[2016,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Prognostic Utility of Brain Natriuretic Peptide in Asymptomatic Patients With Significant Mitral Regurgitation and Preserved Left Ventricular Ejection Fraction","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.amjcard.2015.10.040","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2016 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}