{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T11:31:41Z","timestamp":1784201501344,"version":"3.55.0"},"reference-count":26,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2018,6,1]],"date-time":"2018-06-01T00:00:00Z","timestamp":1527811200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Cardiovascular Research Center"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","ajconline.org","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Cardiology"],"published-print":{"date-parts":[[2018,6]]},"DOI":"10.1016\/j.amjcard.2018.02.045","type":"journal-article","created":{"date-parts":[[2018,3,18]],"date-time":"2018-03-18T14:02:33Z","timestamp":1521381753000},"page":"1534-1539","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":28,"title":["Feasibility of Left Atrial Appendage Occlusion for Left Atrial Appendage Thrombus in Patients With Persistent Atrial Fibrillation"],"prefix":"10.1016","volume":"121","author":[{"given":"Oh-Hyun","family":"Lee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2263-3274","authenticated-orcid":false,"given":"Jung-Sun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui-Nam","family":"Pak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geu-Ru","family":"Hong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chi Young","family":"Shim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae-Sun","family":"Uhm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"In-Jeong","family":"Cho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Boyoung","family":"Joung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheol-Woong","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyun-Jong","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Woong-Chol","family":"Kang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eun-Seok","family":"Shin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rak-kyeong","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Do-Sun","family":"Lim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yangsoo","family":"Jang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.amjcard.2018.02.045_bib0010","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1161\/CIRCULATIONAHA.114.013243","article-title":"Extracranial systemic embolic events in patients with nonvalvular atrial fibrillation: incidence, risk factors, and outcomes","volume":"132","author":"Bekwelem","year":"2015","journal-title":"Circulation"},{"key":"10.1016\/j.amjcard.2018.02.045_bib0015","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1016\/j.jacc.2014.03.022","article-title":"2014 AHA\/ACC\/HRS guideline for the management of patients with atrial fibrillation: a report of the American College of Cardiology\/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society","volume":"64","author":"January","year":"2014","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.amjcard.2018.02.045_bib0020","doi-asserted-by":"crossref","first-page":"2893","DOI":"10.1093\/eurheartj\/ehw210","article-title":"2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS","volume":"37","author":"Kirchhof","year":"2016","journal-title":"Eur Heart J"},{"key":"10.1016\/j.amjcard.2018.02.045_bib0025","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1016\/0003-4975(95)00887-X","article-title":"Appendage obliteration to reduce stroke in cardiac surgical patients with atrial fibrillation","volume":"61","author":"Blackshear","year":"1996","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.amjcard.2018.02.045_bib0030","doi-asserted-by":"crossref","first-page":"1622","DOI":"10.1016\/S0735-1097(98)00146-6","article-title":"Transesophageal echocardiographic correlates of clinical risk of thromboembolism in nonvalvular atrial fibrillation","volume":"31","author":"Zabalgoitia","year":"1998","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.amjcard.2018.02.045_bib0035","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1253\/circj.CJ-16-1089","article-title":"Left atrial appendage thrombi formation in Japanese non-valvular atrial fibrillation patients during anticoagulation therapy\u2014warfarin vs. direct oral anticoagulants","volume":"81","author":"Kawabata","year":"2017","journal-title":"Circ J"},{"key":"10.1016\/j.amjcard.2018.02.045_bib0040","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.jacep.2016.01.004","article-title":"Prevalence of left atrial thrombus detection by transesophageal echocardiography: a comparison of continuous non\u2013vitamin K antagonist oral anticoagulant versus warfarin therapy in patients undergoing catheter ablation for atrial fibrillation","volume":"2","author":"Frenkel","year":"2016","journal-title":"JACC Clin Electrophysiol"},{"key":"10.1016\/j.amjcard.2018.02.045_bib0045","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCEP.116.004127","article-title":"Locked away: percutaneous closure of a malignant left atrial appendage to constrain an unresolvable thrombus","author":"Dugo","year":"2016","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"10.1016\/j.amjcard.2018.02.045_bib0050","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.ijcard.2016.12.141","article-title":"Left atrial appendage closure in a patient with left atrial appendage thrombus using a novel fish ball technique","volume":"234","author":"Bellmann","year":"2017","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.amjcard.2018.02.045_bib0055","doi-asserted-by":"crossref","first-page":"e224","DOI":"10.2459\/JCM.0000000000000323","article-title":"Transcatheter occlusion of left atrial appendage with persistent thrombus using a trans-radial embolic protection device","volume":"17","author":"Cammalleri","year":"2016","journal-title":"J Cardiovasc Med (Hagerstown)"},{"key":"10.1016\/j.amjcard.2018.02.045_bib0060","article-title":"Percutaneous left atrial appendage occlusion in patients with atrial fibrillation and left appendage thrombus: feasibility, safety and clinical efficacy","author":"Tarantini","year":"2017","journal-title":"EuroIntervention"},{"key":"10.1016\/j.amjcard.2018.02.045_bib0065","doi-asserted-by":"crossref","first-page":"1329.e1","DOI":"10.1016\/j.cjca.2012.09.016","article-title":"Self-expandable device for percutaneous closing of left atrial appendage with organized thrombus in a patient with permanent atrial fibrillation","volume":"29","author":"Pak","year":"2013","journal-title":"Can J Cardiol"},{"key":"10.1016\/j.amjcard.2018.02.045_bib0070","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.4244\/EIJV10I10A199","article-title":"Percutaneous left atrial appendage closure in patients with left atrial appendage thrombus","volume":"10","author":"Meincke","year":"2015","journal-title":"EuroIntervention"},{"key":"10.1016\/j.amjcard.2018.02.045_bib0075","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1016\/j.acvd.2016.02.012","article-title":"Extending percutaneous left atrial appendage closure indications using the AMPLATZER\u2122 Cardiac Plug device in patients with persistent left atrial appendage thrombus: the thrombus trapping technique","volume":"109","author":"Jalal","year":"2016","journal-title":"Arch Cardiovasc Dis"},{"key":"10.1016\/j.amjcard.2018.02.045_bib0080","doi-asserted-by":"crossref","first-page":"408","DOI":"10.4244\/EIJV8I3A61","article-title":"Percutaneous mechanical thrombectomy of left atrial appendage thrombus with bilateral neuro-embolic protection followed by closure of left atrial appendage","volume":"8","author":"Bokhari","year":"2012","journal-title":"EuroIntervention"},{"key":"10.1016\/j.amjcard.2018.02.045_bib0085","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.ijcard.2016.08.171","article-title":"First case of percutaneous left atrial appendage closure by Amulet\u2122 device in a patient with left atrial appendage thrombus","volume":"223","author":"Aytemir","year":"2016","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.amjcard.2018.02.045_bib0090","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.4244\/EIJY14M09_18","article-title":"EHRA\/EAPCI expert consensus statement on catheter-based left atrial appendage occlusion","volume":"10","author":"Meier","year":"2015","journal-title":"EuroIntervention"},{"key":"10.1016\/j.amjcard.2018.02.045_bib0095","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1016\/j.echo.2013.07.009","article-title":"Guidelines for performing a comprehensive transesophageal echocardiographic examination: recommendations from the American Society of Echocardiography and the Society of Cardiovascular Anesthesiologists","volume":"26","author":"Hahn","year":"2013","journal-title":"J Am Soc Echocardiogr"},{"key":"10.1016\/j.amjcard.2018.02.045_bib0100","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1046\/j.1540-8175.2002.00319.x","article-title":"Prevalence and clinical significance of left atrial spontaneous echo contrast detected by transesophageal echocardiography","volume":"19","author":"Vincelj","year":"2002","journal-title":"Echocardiography"},{"key":"10.1016\/j.amjcard.2018.02.045_bib0105","first-page":"4","article-title":"Percutaneous left atrial appendage occlusion: the Munich consensus document on definitions, endpoints, and data collection requirements for clinical studies","volume":"19","author":"Tzikas","year":"2017","journal-title":"Europace"},{"key":"10.1016\/j.amjcard.2018.02.045_bib0110","doi-asserted-by":"crossref","first-page":"2032","DOI":"10.1016\/j.jacc.2009.07.037","article-title":"Role of the CHADS 2 score in the evaluation of thromboembolic risk in patients with atrial fibrillation undergoing transesophageal echocardiography before pulmonary vein isolation","volume":"54","author":"Puwanant","year":"2009","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.amjcard.2018.02.045_bib0115","doi-asserted-by":"crossref","DOI":"10.1136\/heartjnl-2012-301799","article-title":"Importance of the underlying substrate in determining thrombus location in atrial fibrillation: implications for left atrial appendage closure","author":"Mahajan","year":"2012","journal-title":"Heart"},{"key":"10.1016\/j.amjcard.2018.02.045_bib0120","doi-asserted-by":"crossref","first-page":"1760","DOI":"10.1161\/01.STR.27.10.1760","article-title":"Stroke severity in atrial fibrillation","volume":"27","author":"Lin","year":"1996","journal-title":"Stroke"},{"key":"10.1016\/j.amjcard.2018.02.045_bib0125","doi-asserted-by":"crossref","first-page":"2422","DOI":"10.1093\/eurheartj\/ehi505","article-title":"Atrial fibrillation management: a prospective survey in ESC member countries: the Euro Heart Survey on Atrial Fibrillation","volume":"26","author":"Nieuwlaat","year":"2005","journal-title":"Eur Heart J"},{"key":"10.1016\/j.amjcard.2018.02.045_bib0130","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1067\/mhj.2003.91","article-title":"Left atrial thrombus predicts transient ischemic attack in patients with atrial fibrillation","volume":"145","author":"Stoddard","year":"2003","journal-title":"Am Heart J"},{"key":"10.1016\/j.amjcard.2018.02.045_bib0135","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1016\/j.amjcard.2004.06.010","article-title":"Fate of left atrial thrombi in patients with atrial fibrillation determined by transesophageal echocardiography and cerebral magnetic resonance imaging","volume":"94","author":"Bernhardt","year":"2004","journal-title":"Am J Cardiol"}],"container-title":["The American Journal of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002914918302819?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002914918302819?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,8,23]],"date-time":"2018-08-23T02:30:22Z","timestamp":1534991422000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002914918302819"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,6]]},"references-count":26,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2018,6]]}},"alternative-id":["S0002914918302819"],"URL":"https:\/\/doi.org\/10.1016\/j.amjcard.2018.02.045","relation":{},"ISSN":["0002-9149"],"issn-type":[{"value":"0002-9149","type":"print"}],"subject":[],"published":{"date-parts":[[2018,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Feasibility of Left Atrial Appendage Occlusion for Left Atrial Appendage Thrombus in Patients With Persistent Atrial Fibrillation","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.amjcard.2018.02.045","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}