{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T02:11:28Z","timestamp":1767665488262},"reference-count":28,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2018,6,1]],"date-time":"2018-06-01T00:00:00Z","timestamp":1527811200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100004836","name":"Danish Council for Independent Research","doi-asserted-by":"crossref","award":["DFF-6110-00584"],"award-info":[{"award-number":["DFF-6110-00584"]}],"id":[{"id":"10.13039\/501100004836","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","ajconline.org","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Cardiology"],"published-print":{"date-parts":[[2018,6]]},"DOI":"10.1016\/j.amjcard.2018.02.051","type":"journal-article","created":{"date-parts":[[2018,3,18]],"date-time":"2018-03-18T18:02:52Z","timestamp":1521396172000},"page":"1610-1616","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":26,"title":["Incidence and Mortality of Adults With Pulmonary Hypertension and Congenital Heart Disease"],"prefix":"10.1016","volume":"121","author":[{"given":"Sara S\u00f8ndergaard","family":"Schwartz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicolas","family":"Madsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henning B\u00e6kgaard","family":"Laursen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Russel","family":"Hirsch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Morten Sm\u00e6rup","family":"Olsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.amjcard.2018.02.051_bib0010","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1161\/CIRCULATIONAHA.106.627224","article-title":"Congenital heart disease in the general population: changing prevalence and age distribution","volume":"115","author":"Marelli","year":"2007","journal-title":"Circulation"},{"key":"10.1016\/j.amjcard.2018.02.051_bib0015","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/j.ahj.2008.10.017","article-title":"National time trends in congenital heart defects, Denmark, 1977\u20132005","volume":"157","author":"Oyen","year":"2009","journal-title":"Am Heart J"},{"key":"10.1016\/j.amjcard.2018.02.051_bib0020","doi-asserted-by":"crossref","first-page":"1322","DOI":"10.1016\/j.amjcard.2010.06.062","article-title":"Late mortality among Danish patients with congenital heart defect","volume":"106","author":"Olsen","year":"2010","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.amjcard.2018.02.051_bib0025","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1016\/j.jacc.2010.03.085","article-title":"Changing mortality in congenital heart disease","volume":"56","author":"Khairy","year":"2010","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.amjcard.2018.02.051_bib0030","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/j.ccl.2015.07.001","article-title":"Adult congenital heart disease: scope of the problem","volume":"33","author":"Mazor Dray","year":"2015","journal-title":"Cardiol Clin"},{"key":"10.1016\/j.amjcard.2018.02.051_bib0035","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1136\/hrt.2006.098848","article-title":"Pulmonary arterial hypertension in adults born with a heart septal defect: the Euro Heart Survey on adult congenital heart disease","volume":"93","author":"Engelfriet","year":"2007","journal-title":"Heart"},{"key":"10.1016\/j.amjcard.2018.02.051_bib0040","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/j.amjcard.2011.03.036","article-title":"Outcomes of hospitalization in adults in the United States with atrial septal defect, ventricular septal defect, and atrioventricular septal defect","volume":"108","author":"Rodriguez","year":"2011","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.amjcard.2018.02.051_bib0045","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1586\/14779072.2013.811966","article-title":"The challenge of managing pulmonary arterial hypertension in adults with congenital heart disease","volume":"11","author":"Radke","year":"2013","journal-title":"Expert Rev Cardiovasc Ther"},{"key":"10.1016\/j.amjcard.2018.02.051_bib0050","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1183\/09059180.00003512","article-title":"A critical analysis of survival in pulmonary arterial hypertension","volume":"21","author":"O'Callaghan","year":"2012","journal-title":"Eur Respir Rev"},{"key":"10.1016\/j.amjcard.2018.02.051_bib0055","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/j.ijcard.2014.04.072","article-title":"Contemporary prevalence of pulmonary arterial hypertension in adult congenital heart disease following the updated clinical classification","volume":"174","author":"van Riel","year":"2014","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.amjcard.2018.02.051_bib0060","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1016\/j.ijcard.2014.08.009","article-title":"A different view on predictors of pulmonary hypertension in secundum atrial septal defect","volume":"176","author":"Gabriels","year":"2014","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.amjcard.2018.02.051_bib0065","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1161\/CIRCULATIONAHA.108.839464","article-title":"Children and adults with congenital heart disease lost to follow-up: who and when?","volume":"120","author":"Mackie","year":"2009","journal-title":"Circulation"},{"key":"10.1016\/j.amjcard.2018.02.051_bib0070","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1177\/1403494810387965","article-title":"The Danish Civil Registration System","volume":"39","author":"Pedersen","year":"2011","journal-title":"Scand J Public Health"},{"key":"10.1016\/j.amjcard.2018.02.051_bib0075","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1111\/j.1651-2227.1980.tb07332.x","article-title":"Some epidemiological aspects of congenital heart disease in Denmark","volume":"69","author":"Laursen","year":"1980","journal-title":"Acta Paediatr Scand"},{"key":"10.1016\/j.amjcard.2018.02.051_bib0080","first-page":"263","article-title":"The Danish National Hospital Register. A valuable source of data for modern health sciences","volume":"46","author":"Andersen","year":"1999","journal-title":"Dan Med Bull"},{"key":"10.1016\/j.amjcard.2018.02.051_bib0085","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1177\/1403494811401482","article-title":"The Danish National Patient Register","volume":"39","author":"Lynge","year":"2011","journal-title":"Scand J Public Health"},{"key":"10.1016\/j.amjcard.2018.02.051_bib0090","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.115.003076","article-title":"Congenital heart disease with and without cyanotic potential and the long-term risk of diabetes mellitus: a population-based follow-up study","volume":"5","author":"Madsen","year":"2016","journal-title":"J Am Heart Assoc"},{"key":"10.1016\/j.amjcard.2018.02.051_bib0095","doi-asserted-by":"crossref","first-page":"1706","DOI":"10.1161\/CIRCULATIONAHA.110.002832","article-title":"Congenital heart defects and developmental and other psychiatric disorders: a Danish nationwide cohort study","volume":"124","author":"Olsen","year":"2011","journal-title":"Circulation"},{"key":"10.1016\/j.amjcard.2018.02.051_bib0100","series-title":"EUROCAT Guide 1.3 and reference documents; Instructions for the Registration and Surveillance of Congenital Anomalies, 2005","author":"European Survaillance of Congenital Anomalies, EUROCAT","year":"2016"},{"key":"10.1016\/j.amjcard.2018.02.051_bib0105","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1183\/09031936.00092306","article-title":"An epidemiological study of pulmonary arterial hypertension","volume":"30","author":"Peacock","year":"2007","journal-title":"Eur Respir J"},{"key":"10.1016\/j.amjcard.2018.02.051_bib0110","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1164\/rccm.200510-1668OC","article-title":"Pulmonary arterial hypertension in France: results from a national registry","volume":"173","author":"Humbert","year":"2006","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.amjcard.2018.02.051_bib0115","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1016\/j.jacc.2011.03.033","article-title":"Diagnosis of pulmonary hypertension in the congenital heart disease adult population impact on outcomes","volume":"58","author":"Lowe","year":"2011","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.amjcard.2018.02.051_bib0120","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1378\/chest.10-1166","article-title":"Delay in recognition of pulmonary arterial hypertension: factors identified from the REVEAL Registry","volume":"140","author":"Brown","year":"2011","journal-title":"Chest"},{"key":"10.1016\/j.amjcard.2018.02.051_bib0125","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1016\/j.ijcard.2015.02.031","article-title":"Pulmonary hypertension and congenital heart disease: An insight from the REHAP National Registry","volume":"184","author":"Alonso-Gonzalez","year":"2015","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.amjcard.2018.02.051_bib0130","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.1093\/eurheartj\/ehq032","article-title":"Mortality in adult congenital heart disease","volume":"31","author":"Verheugt","year":"2010","journal-title":"Eur Heart J"},{"key":"10.1016\/j.amjcard.2018.02.051_bib0135","doi-asserted-by":"crossref","first-page":"61","DOI":"10.2147\/CLEP.S15627","article-title":"Children diagnosed with congenital cardiac malformations at the national university departments of pediatric cardiology: positive predictive values of data in the Danish National Patient Registry","volume":"3","author":"Agergaard","year":"2011","journal-title":"Clin Epidemiol"},{"key":"10.1016\/j.amjcard.2018.02.051_bib0140","doi-asserted-by":"crossref","first-page":"e012832","DOI":"10.1136\/bmjopen-2016-012832","article-title":"Positive predictive value of cardiovascular diagnoses in the Danish National Patient Registry: a validation study","volume":"6","author":"Sundboll","year":"2016","journal-title":"BMJ Open"},{"key":"10.1016\/j.amjcard.2018.02.051_bib0145","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1016\/j.ejheart.2008.05.006","article-title":"Accuracy of a heart failure diagnosis in administrative registers","volume":"10","author":"Kumler","year":"2008","journal-title":"Eur J Heart Fail"}],"container-title":["The American Journal of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000291491830287X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000291491830287X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,5,19]],"date-time":"2020-05-19T04:49:18Z","timestamp":1589863758000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S000291491830287X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,6]]},"references-count":28,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2018,6]]}},"alternative-id":["S000291491830287X"],"URL":"https:\/\/doi.org\/10.1016\/j.amjcard.2018.02.051","relation":{},"ISSN":["0002-9149"],"issn-type":[{"value":"0002-9149","type":"print"}],"subject":[],"published":{"date-parts":[[2018,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Incidence and Mortality of Adults With Pulmonary Hypertension and Congenital Heart Disease","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.amjcard.2018.02.051","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}