{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T13:31:58Z","timestamp":1785936718310,"version":"3.56.0"},"reference-count":21,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,7,6]],"date-time":"2022-07-06T00:00:00Z","timestamp":1657065600000},"content-version":"am","delay-in-days":339,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["15K19402"],"award-info":[{"award-number":["15K19402"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013642","name":"Japan Heart Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100013642","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["ajconline.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Cardiology"],"published-print":{"date-parts":[[2021,8]]},"DOI":"10.1016\/j.amjcard.2021.04.039","type":"journal-article","created":{"date-parts":[[2021,6,11]],"date-time":"2021-06-11T08:34:41Z","timestamp":1623400481000},"page":"125-131","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"special_numbering":"C","title":["Long-Term Prognostic Significance of Ventricular Repolarization Dispersion in Patients with Cardiac Sarcoidosis"],"prefix":"10.1016","volume":"152","author":[{"given":"Yuta","family":"Kobayashi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiyuki","family":"Nagai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sakae","family":"Takenaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshiya","family":"Kato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hirokazu","family":"Komoriyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nobutaka","family":"Nagano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiwamu","family":"Kamiya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takao","family":"Konishi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takuma","family":"Sato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazunori","family":"Omote","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shingo","family":"Tsujinaga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyuki","family":"Iwano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kengo","family":"Kusano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoshi","family":"Yasuda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hisao","family":"Ogawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hatsue","family":"Ishibashi-Ueda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshihisa","family":"Anzai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.amjcard.2021.04.039_bib0001","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1007\/s10840-005-4592-4","article-title":"Tpeak-Tend interval as an index of global dispersion of ventricular repolarization: evaluations using monophasic action potential mapping of the epi- and endocardium in swine","volume":"14","author":"Xia","year":"2005","journal-title":"J Interv Card Electrophysiol"},{"key":"10.1016\/j.amjcard.2021.04.039_bib0002","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1016\/j.hrthm.2017.05.031","article-title":"The Tpeak - Tend interval as an electrocardiographic risk marker of arrhythmic and mortality outcomes: a systematic review and meta-analysis","volume":"14","author":"Tse","year":"2017","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.amjcard.2021.04.039_bib0003","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1016\/j.jelectrocard.2008.07.016","article-title":"T(p-e)\/QT ratio as an index of arrhythmogenesis","volume":"41","author":"Gupta","year":"2008","journal-title":"J Electrocardiol"},{"key":"10.1016\/j.amjcard.2021.04.039_bib0004","doi-asserted-by":"crossref","first-page":"2329","DOI":"10.1253\/circj.CJ-19-0508","article-title":"JCS 2016 guideline on diagnosis and treatment of cardiac sarcoidosis- digest version","volume":"83","author":"Terasaki","year":"2019","journal-title":"Circ J"},{"key":"10.1016\/j.amjcard.2021.04.039_bib0005","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1161\/01.CIR.6.3.378","article-title":"The measurement of the Q-T interval of the electrocardiogram","volume":"6","author":"Lepeschkin","year":"1952","journal-title":"Circulation"},{"key":"10.1016\/j.amjcard.2021.04.039_bib0006","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1161\/CIRCEP.110.960658","article-title":"Prolonged Tpeak-to-tend interval on the resting ECG is associated with increased risk of sudden cardiac death","volume":"4","author":"Panikkath","year":"2011","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"10.1016\/j.amjcard.2021.04.039_bib0007","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1161\/CIRCEP.113.000356","article-title":"Predictive value of electrocardiographic T-wave morphology parameters and T-wave peak to T-wave end interval for sudden cardiac death in the general population","volume":"6","author":"Porthan","year":"2013","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"10.1016\/j.amjcard.2021.04.039_bib0008","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1161\/CIRCULATIONAHA.117.033502","article-title":"2017 cardiovascular and stroke endpoint definitions for clinical trials","volume":"137","author":"Hicks","year":"2018","journal-title":"Circulation"},{"key":"10.1016\/j.amjcard.2021.04.039_bib0009","doi-asserted-by":"crossref","first-page":"1356","DOI":"10.1161\/01.CIR.67.6.1356","article-title":"Characteristics and possible mechanism of ventricular arrhythmia dependent on the dispersion of action potential durations","volume":"67","author":"Kuo","year":"1983","journal-title":"Circulation"},{"key":"10.1016\/j.amjcard.2021.04.039_bib0010","doi-asserted-by":"crossref","first-page":"1729","DOI":"10.1161\/01.RES.68.6.1729","article-title":"A subpopulation of cells with unique electrophysiological properties in the deep subepicardium of the canine ventricle. The M cell","volume":"68","author":"Sicouri","year":"1991","journal-title":"Circ Res"},{"key":"10.1016\/j.amjcard.2021.04.039_bib0011","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1111\/j.1540-8167.1999.tb00287.x","article-title":"The M cell: its contribution to the ECG and to normal and abnormal electrical function of the heart","volume":"10","author":"Antzelevitch","year":"1999","journal-title":"J Cardiovasc Electrophysiol"},{"key":"10.1016\/j.amjcard.2021.04.039_bib0012","doi-asserted-by":"crossref","first-page":"H2024","DOI":"10.1152\/ajpheart.00355.2007","article-title":"Role of spatial dispersion of repolarization in inherited and acquired sudden cardiac death syndromes","volume":"293","author":"Antzelevitch","year":"2007","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1016\/j.amjcard.2021.04.039_bib0013","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0179980","article-title":"Immunohistochemical identification of Propionibacterium acnes in granuloma and inflammatory cells of myocardial tissues obtained from cardiac sarcoidosis patients","volume":"12","author":"Asakawa","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.amjcard.2021.04.039_bib0014","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1161\/CIRCEP.114.002145","article-title":"Ventricular tachycardia in cardiac sarcoidosis: characterization of ventricular substrate and outcomes of catheter ablation","volume":"8","author":"Kumar","year":"2015","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"10.1016\/j.amjcard.2021.04.039_bib0015","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.jacep.2017.09.175","article-title":"Characterization of the electroanatomic substrate in cardiac sarcoidosis: correlation with imaging findings of scar and inflammation","volume":"4","author":"Muser","year":"2018","journal-title":"JACC Clin Electrophysiol"},{"key":"10.1016\/j.amjcard.2021.04.039_bib0016","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1093\/europace\/eus362","article-title":"The relationship between left ventricular scar and ventricular repolarization in patients with coronary artery disease: insights from late gadolinium enhancement magnetic resonance imaging","volume":"15","author":"Scott","year":"2013","journal-title":"Europace"},{"key":"10.1016\/j.amjcard.2021.04.039_bib0017","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.joa.2016.10.005","article-title":"Diffuse interstitial fibrosis assessed by cardiac magnetic resonance is associated with dispersion of ventricular repolarization in patients with hypertrophic cardiomyopathy","volume":"33","author":"Hurtado-de-Mendoza","year":"2017","journal-title":"J Arrhythm"},{"key":"10.1016\/j.amjcard.2021.04.039_bib0018","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1016\/j.hrthm.2012.02.010","article-title":"Long-term follow-up of patients with cardiac sarcoidosis and implantable cardioverter-defibrillators","volume":"9","author":"Betensky","year":"2012","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.amjcard.2021.04.039_bib0019","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/j.ijcard.2017.04.044","article-title":"Early and frequent defibrillator discharge in patients with cardiac sarcoidosis compared with patients with idiopathic dilated cardiomyopathy","volume":"240","author":"Takaya","year":"2017","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.amjcard.2021.04.039_bib0020","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/j.jcmg.2016.05.009","article-title":"Prognostic value of myocardial scarring on CMR in patients with cardiac sarcoidosis","volume":"10","author":"Coleman","year":"2017","journal-title":"JACC Cardiovasc Imaging"},{"key":"10.1016\/j.amjcard.2021.04.039_bib0021","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.jacc.2013.09.022","article-title":"Cardiac positron emission tomography enhances prognostic assessments of patients with suspected cardiac sarcoidosis","volume":"63","author":"Blankstein","year":"2014","journal-title":"J Am Coll Cardiol"}],"container-title":["The American Journal of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002914921004197?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002914921004197?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T06:38:38Z","timestamp":1757572718000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002914921004197"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,8]]},"references-count":21,"alternative-id":["S0002914921004197"],"URL":"https:\/\/doi.org\/10.1016\/j.amjcard.2021.04.039","relation":{},"ISSN":["0002-9149"],"issn-type":[{"value":"0002-9149","type":"print"}],"subject":[],"published":{"date-parts":[[2021,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Long-Term Prognostic Significance of Ventricular Repolarization Dispersion in Patients with Cardiac Sarcoidosis","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.amjcard.2021.04.039","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}