{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T21:08:59Z","timestamp":1793653739436,"version":"4.5.1"},"reference-count":19,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["ajconline.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Cardiology"],"published-print":{"date-parts":[[2021,9]]},"DOI":"10.1016\/j.amjcard.2021.05.048","type":"journal-article","created":{"date-parts":[[2021,7,6]],"date-time":"2021-07-06T00:19:09Z","timestamp":1625530749000},"page":"99-105","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"special_numbering":"C","title":["Impact of Digoxin Use on Interstage Outcomes of Single Ventricle Heart Disease (From a NPC-QIC Registry Analysis)"],"prefix":"10.1016","volume":"154","author":[{"given":"Rachel E.","family":"Klausner","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Parra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen","family":"Kohl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tyler","family":"Brown","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Garick D.","family":"Hill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"LuAnn","family":"Minich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7068-0625","authenticated-orcid":false,"given":"Justin","family":"Godown","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.amjcard.2021.05.048_bib0001","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.115.002376","article-title":"Digoxin use is associated with reduced interstage mortality in patients with no history of arrhythmia after stage i palliation for single ventricle heart disease","volume":"5","author":"Brown","year":"2016","journal-title":"J Am Heart Assoc"},{"key":"10.1016\/j.amjcard.2021.05.048_bib0002","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.115.002566","article-title":"Association of digoxin with interstage mortality: results from the pediatric heart network single ventricle reconstruction trial public use dataset","volume":"5","author":"Oster","year":"2016","journal-title":"J Am Heart Assoc"},{"key":"10.1016\/j.amjcard.2021.05.048_bib0003","doi-asserted-by":"crossref","DOI":"10.1016\/j.ppedcard.2020.101299","article-title":"Digoxin utilization following the Norwood procedure in patients with hypoplastic left heart syndrome: a multicenter database analysis","author":"Klausner","year":"2020","journal-title":"Prog Pediatr Cardiol"},{"key":"10.1016\/j.amjcard.2021.05.048_bib0004","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1007\/s00246-021-02543-y","article-title":"Trends in discharge prescription of digoxin after norwood operation: an analysis of data from the pediatric health information system (PHIS) database","volume":"42","author":"O'Byrne","year":"2021","journal-title":"Pediatr Cardiol"},{"key":"10.1016\/j.amjcard.2021.05.048_bib0005","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1161\/CIRCOUTCOMES.115.001956","article-title":"Improvement in Interstage survival in a national pediatric cardiology learning network","volume":"8","author":"Anderson","year":"2015","journal-title":"Circ Cardiovasc Qual Outcomes"},{"key":"10.1016\/j.amjcard.2021.05.048_bib0006","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1016\/j.jtcvs.2019.11.001","article-title":"Development of a validated risk score for interstage death or transplant after stage I palliation for single-ventricle heart disease","volume":"160","author":"Ahmed","year":"2019","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.amjcard.2021.05.048_bib0007","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/S0735-1097(20)31174-8","article-title":"Digoxin is associated with improved transplant-free interstage survival in high-risk but not low-risk patients with hypoplastic left heart syndrome (HLHS)","volume":"75","author":"Brown","year":"2020","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.amjcard.2021.05.048_bib0008","unstructured":"Centers for Disease Control and Prevention, National Center for Health Statistics: CDC Growth Charts. 2021"},{"key":"10.1016\/j.amjcard.2021.05.048_bib0009","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1111\/chd.12760","article-title":"Perspective. Digoxin for interstage single ventricle patients: what could possibly go wrong?","volume":"14","author":"Van Hare","year":"2019","journal-title":"Congenit Heart Dis"},{"key":"10.1016\/j.amjcard.2021.05.048_bib0010","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1017\/S1047951118000926","article-title":"Examining variation in interstage mortality rates across the National Pediatric Cardiology Quality Improvement Collaborative: do lower-mortality centres have lower-risk patients?","volume":"28","author":"Bates","year":"2018","journal-title":"Cardiol Young"},{"key":"10.1016\/j.amjcard.2021.05.048_bib0011","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1097\/HPC.0b013e318221e7dd","article-title":"Digoxin: clinical highlights: a review of digoxin and its use in contemporary medicine","volume":"10","author":"Ehle","year":"2011","journal-title":"Crit Pathw Cardiol"},{"key":"10.1016\/j.amjcard.2021.05.048_bib0012","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1161\/CIRCEP.112.972620","article-title":"The study of antiarrhythmic medications in infancy (SAMIS): a multicenter, randomized controlled trial comparing the efficacy and safety of digoxin versus propranolol for prophylaxis of supraventricular tachycardia in infants","volume":"5","author":"Sanatani","year":"2012","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"10.1016\/j.amjcard.2021.05.048_bib0013","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1007\/s00246-018-1884-x","article-title":"Digoxin use in infants with single ventricle physiology: secondary analysis of the pediatric heart network infant single ventricle trial public use dataset","volume":"39","author":"Truong","year":"2018","journal-title":"Pediatr Cardiol"},{"key":"10.1016\/j.amjcard.2021.05.048_bib0014","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1097\/HCO.0b013e32835dceaf","article-title":"Single-ventricle infant home monitoringprograms: outcomes and impact","volume":"28","author":"Hehir","year":"2013","journal-title":"Curr Opin Cardiol"},{"key":"10.1016\/j.amjcard.2021.05.048_bib0015","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1016\/j.jtcvs.2013.04.006","article-title":"Home monitoring program reduces interstage mortality after the modified Norwood procedure","volume":"147","author":"Siehr","year":"2014","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.amjcard.2021.05.048_bib0016","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1016\/S0022-5223(03)00071-0","article-title":"Home surveillance program prevents interstage mortality after the Norwood procedure","volume":"126","author":"Ghanayem","year":"2003","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.amjcard.2021.05.048_bib0017","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.athoracsur.2019.07.062","article-title":"Selective use of inpatient interstage management after norwood procedure","volume":"109","author":"Hill","year":"2020","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.amjcard.2021.05.048_bib0018","article-title":"In-hospital interstage improves interstage survival after the Norwood stage 1 operation","author":"Michielon","year":"2020","journal-title":"Euro J Cardio"},{"key":"10.1016\/j.amjcard.2021.05.048_bib0019","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1016\/j.jtcvs.2019.11.094","article-title":"Commentary: the over\/under isset at 17? Let's not gamble with discharge after the Norwood operation","volume":"160","author":"Meza","year":"2020","journal-title":"J Thorac Cardiovasc Surg"}],"container-title":["The American Journal of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002914921005270?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002914921005270?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T06:39:14Z","timestamp":1757572754000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002914921005270"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9]]},"references-count":19,"alternative-id":["S0002914921005270"],"URL":"https:\/\/doi.org\/10.1016\/j.amjcard.2021.05.048","relation":{},"ISSN":["0002-9149"],"issn-type":[{"value":"0002-9149","type":"print"}],"subject":[],"published":{"date-parts":[[2021,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Impact of Digoxin Use on Interstage Outcomes of Single Ventricle Heart Disease (From a NPC-QIC Registry Analysis)","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.amjcard.2021.05.048","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}