{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T23:36:50Z","timestamp":1787960210017,"version":"build-2784847793"},"reference-count":32,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["ajconline.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Cardiology"],"published-print":{"date-parts":[[2022,5]]},"DOI":"10.1016\/j.amjcard.2022.01.048","type":"journal-article","created":{"date-parts":[[2022,3,19]],"date-time":"2022-03-19T08:19:40Z","timestamp":1647677980000},"page":"105-114","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"special_numbering":"C","title":["Effect of Chronic Kidney Disease on 5-Year Outcome in Patients With Heart Failure and Secondary Mitral Regurgitation Undergoing Percutaneous MitraClip Insertion"],"prefix":"10.1016","volume":"171","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0810-6032","authenticated-orcid":false,"given":"Antonio","family":"Sisinni","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5108-0579","authenticated-orcid":false,"given":"Andrea","family":"Munaf\u00f2","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlo Andrea","family":"Pivato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marianna","family":"Adamo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurizio","family":"Taramasso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4731-4384","authenticated-orcid":false,"given":"Andrea","family":"Scotti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio L.M.","family":"Parlati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonardo","family":"Italia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9573-7029","authenticated-orcid":false,"given":"Davide","family":"Voci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicola","family":"Buzzatti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3075-0203","authenticated-orcid":false,"given":"Paolo","family":"Denti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7972-0689","authenticated-orcid":false,"given":"Francesco","family":"Ancona","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0797-3636","authenticated-orcid":false,"given":"Alessandra","family":"Marengo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2966-1518","authenticated-orcid":false,"given":"Alessandra","family":"Sala","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6101-5298","authenticated-orcid":false,"given":"Francesca","family":"Bodega","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7211-8399","authenticated-orcid":false,"given":"Martina Maria","family":"Ruffo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salvatore","family":"Curello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Castiglioni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9732-9459","authenticated-orcid":false,"given":"Matteo","family":"Montorfano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9329-7437","authenticated-orcid":false,"given":"Michele","family":"de Bonis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ottavio","family":"Alfieri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eustachio","family":"Agricola","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Colombo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Maisano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6691-8568","authenticated-orcid":false,"given":"Marco","family":"Metra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Margonato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1319-0010","authenticated-orcid":false,"given":"Cosmo","family":"Godino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.amjcard.2022.01.048_bib0001","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1016\/j.jacc.2020.12.047","article-title":"3-year outcomes of transcatheter mitral valve repair in patients with heart failure","volume":"77","author":"Mack","year":"2021","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.amjcard.2022.01.048_bib0002","doi-asserted-by":"crossref","first-page":"2307","DOI":"10.1056\/NEJMoa1806640","article-title":"Transcatheter mitral-valve repair in patients with heart failure","volume":"379","author":"Stone","year":"2018","journal-title":"N Engl J Med"},{"key":"10.1016\/j.amjcard.2022.01.048_bib0003","doi-asserted-by":"crossref","first-page":"2297","DOI":"10.1056\/NEJMoa1805374","article-title":"Percutaneous repair or medical treatment for secondary mitral regurgitation","volume":"379","author":"Obadia","year":"2018","journal-title":"N Engl J Med"},{"key":"10.1016\/j.amjcard.2022.01.048_bib0004","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1080\/24748706.2020.1753899","article-title":"MitraClip Treatment of Secondary Mitral Regurgitation in Heart Failure with Reduced Ejection Fraction: Lessons and Implications from Trials and Registries","volume":"4","author":"Godino","year":"2020","journal-title":"Structural Heart"},{"key":"10.1016\/j.amjcard.2022.01.048_bib0005","doi-asserted-by":"crossref","first-page":"1619","DOI":"10.1002\/ejhf.1616","article-title":"Percutaneous repair or medical treatment for secondary mitral regurgitation: outcomes at 2\u2009years","volume":"21","author":"Iung","year":"2019","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.amjcard.2022.01.048_bib0006","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.ijcard.2018.08.023","article-title":"Long-term outcome, survival and predictors of mortality after MitraClip therapy: Results from the German Transcatheter Mitral Valve Interventions (TRAMI) registry","volume":"277","author":"Kalbacher","year":"2019","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.amjcard.2022.01.048_bib0007","doi-asserted-by":"crossref","first-page":"1052","DOI":"10.1016\/j.jacc.2013.02.094","article-title":"Percutaneous mitral valve interventions in the real world: early and 1-year results from the ACCESS-EU, a prospective, multicenter, nonrandomized post-approval study of the MitraClip therapy in Europe","volume":"62","author":"Maisano","year":"2013","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.amjcard.2022.01.048_bib0008","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.jjcc.2010.09.004","article-title":"Chronic kidney disease and heart failure\u2013Bidirectional close link and common therapeutic goal","volume":"57","author":"Shiba","year":"2011","journal-title":"J Cardiol"},{"key":"10.1016\/j.amjcard.2022.01.048_bib0009","doi-asserted-by":"crossref","first-page":"1304","DOI":"10.1016\/j.kint.2019.02.022","article-title":"Conference Participants. Heart failure in chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference","volume":"95","author":"House","year":"2019","journal-title":"Kidney Int"},{"key":"10.1016\/j.amjcard.2022.01.048_bib0010","doi-asserted-by":"crossref","first-page":"e840","DOI":"10.1161\/CIR.0000000000000664","volume":"139","author":"Rangaswami","year":"2019","journal-title":"Circulation"},{"key":"10.1016\/j.amjcard.2022.01.048_bib0011","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1016\/j.jjcc.2016.03.004","article-title":"Interaction between renal function and percutaneous edge-to-edge mitral valve repair using MitraClip","volume":"69","author":"Kaneko","year":"2017","journal-title":"J Cardiol"},{"key":"10.1016\/j.amjcard.2022.01.048_bib0012","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCINTERVENTIONS.113.001349","article-title":"Evaluation of renal function before and after percutaneous mitral valve repair","volume":"8","author":"Wang","year":"2015","journal-title":"Circ Cardiovasc Interv"},{"key":"10.1016\/j.amjcard.2022.01.048_bib0013","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.ijcard.2015.06.137","article-title":"Effect of advanced chronic kidney disease in clinical and echocardiographic outcomes of patients treated with MitraClip system","volume":"198","author":"Est\u00e9vez-Loureiro","year":"2015","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.amjcard.2022.01.048_bib0014","doi-asserted-by":"crossref","first-page":"e1649","DOI":"10.4244\/EIJV11I14A316","article-title":"Impact of chronic kidney disease on outcomes after percutaneous mitral valve repair with the MitraClip system: insights from the GRASP registry","volume":"11","author":"Ohno","year":"2016","journal-title":"EuroIntervention"},{"key":"10.1016\/j.amjcard.2022.01.048_bib0015","doi-asserted-by":"crossref","first-page":"2129","DOI":"10.1093\/eurheartj\/ehw128","volume":"37","author":"Ponikowski","year":"2016","journal-title":"Eur Heart J"},{"key":"10.1016\/j.amjcard.2022.01.048_bib0016","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.ijcard.2018.06.041","article-title":"Two-year cardiac mortality after MitraClip treatment of functional mitral regurgitation in ischemic and non-ischemic dilated cardiomyopathy","volume":"269","author":"Godino","year":"2018","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.amjcard.2022.01.048_bib0017","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.amjcard.2020.12.043","article-title":"MiZ\u00fcBr registry. Prognostic Value of Pre-operative Atrial Fibrillation in patients with secondary mitral regurgitation undergoing mitraclip implantation","volume":"143","author":"Godino","year":"2021","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.amjcard.2022.01.048_bib0018","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1093\/ehjci\/jet105","article-title":"Scientific Document Committee of the European Association of Cardiovascular Imaging. Recommendations for the echocardiographic assessment of native valvular regurgitation: an executive summary from the European Association of Cardiovascular Imaging","volume":"14","author":"Lancellotti","year":"2013","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"10.1016\/j.amjcard.2022.01.048_bib0019","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.echo.2014.10.003","article-title":"Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging","volume":"28","author":"Lang","year":"2015","journal-title":"J Am Soc Echocardiogr"},{"key":"10.1016\/j.amjcard.2022.01.048_bib0020","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1053\/euhj.2000.2296","article-title":"Pulsed Doppler tissue imaging of the velocity of tricuspid annular systolic motion; a new, rapid, and non-invasive method of evaluating right ventricular systolic function","volume":"22","author":"Meluz\u00edn","year":"2001","journal-title":"Eur Heart J"},{"key":"10.1016\/j.amjcard.2022.01.048_bib0021","doi-asserted-by":"crossref","first-page":"604","DOI":"10.7326\/0003-4819-150-9-200905050-00006","article-title":"A new equation to estimate glomerular filtration rate","volume":"150","author":"Levey","year":"2009","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.amjcard.2022.01.048_bib0022","doi-asserted-by":"crossref","first-page":"c179","DOI":"10.1159\/000339789","article-title":"KDIGO clinical practice guidelines for acute kidney injury","volume":"120","author":"Khwaja","year":"2012","journal-title":"Nephron Clin Pract"},{"key":"10.1016\/j.amjcard.2022.01.048_bib0023","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1093\/eurheartj\/ehaa612","article-title":"2020 ESC Guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS)","volume":"42","author":"Hindricks","year":"2021","journal-title":"Eur Heart J"},{"key":"10.1016\/j.amjcard.2022.01.048_bib0024","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1016\/j.jacc.2015.05.046","article-title":"Clinical trial design principles and endpoint definitions for transcatheter mitral valve repair and replacement: Part 1: Clinical trial design principles: A consensus document from the Mitral Valve Academic Research Consortium","volume":"66","author":"Stone","year":"2015","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.amjcard.2022.01.048_bib0025","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1056\/NEJMoa051530","article-title":"Outcome of heart failure with preserved ejection fraction in a population-based study","volume":"355","author":"Bhatia","year":"2006","journal-title":"N Engl J Med"},{"key":"10.1016\/j.amjcard.2022.01.048_bib0026","doi-asserted-by":"crossref","first-page":"1268","DOI":"10.1016\/j.jacc.2007.08.072","article-title":"Cardiorenal interactions: insights from the ESCAPE trial","volume":"51","author":"Nohria","year":"2008","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.amjcard.2022.01.048_bib0027","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1016\/j.jacc.2008.08.080","article-title":"Increased central venous pressure is associated with impaired renal function and mortality in a broad spectrum of patients with cardiovascular disease","volume":"53","author":"Damman","year":"2009","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.amjcard.2022.01.048_bib0028","doi-asserted-by":"crossref","first-page":"1946","DOI":"10.4244\/EIJ-D-16-00190","article-title":"Prognostic implication of post-MitraClip vena contracta area in heart failure patients with functional mitral regurgitation","volume":"12","author":"Alessandrini","year":"2017","journal-title":"EuroIntervention"},{"key":"10.1016\/j.amjcard.2022.01.048_bib0029","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1016\/S0140-6736(20)30045-3","article-title":"Global, regional, and national burden of chronic kidney disease, 1990\u20132017: a systematic analysis for the Global Burden of Disease Study 2017","volume":"395","year":"2020","journal-title":"Lancet"},{"key":"10.1016\/j.amjcard.2022.01.048_bib0030","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.ahj.2015.04.010","article-title":"GRASP-IT Investigators. Predictors of clinical outcomes after edge-to-edge percutaneous mitral valve repair","volume":"170","author":"Capodanno","year":"2015","journal-title":"Am Heart J"},{"key":"10.1016\/j.amjcard.2022.01.048_bib0031","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/j.ijcard.2013.09.014","article-title":"Pathophysiology of cardiorenal syndrome in decompensated heart failure: role of lung-right heart-kidney interaction","volume":"169","author":"Guazzi","year":"2013","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.amjcard.2022.01.048_bib0032","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1016\/j.amjcard.2018.03.358","article-title":"Effect of acute kidney injury after percutaneous mitral valve repair on outcome","volume":"122","author":"Spieker","year":"2018","journal-title":"Am J Cardiol"}],"container-title":["The American Journal of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002914922001217?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002914922001217?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T06:42:21Z","timestamp":1757572941000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002914922001217"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5]]},"references-count":32,"alternative-id":["S0002914922001217"],"URL":"https:\/\/doi.org\/10.1016\/j.amjcard.2022.01.048","relation":{},"ISSN":["0002-9149"],"issn-type":[{"value":"0002-9149","type":"print"}],"subject":[],"published":{"date-parts":[[2022,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effect of Chronic Kidney Disease on 5-Year Outcome in Patients With Heart Failure and Secondary Mitral Regurgitation Undergoing Percutaneous MitraClip Insertion","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.amjcard.2022.01.048","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}