{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T15:37:26Z","timestamp":1772120246410,"version":"3.50.1"},"reference-count":29,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["ajconline.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Cardiology"],"published-print":{"date-parts":[[2022,7]]},"DOI":"10.1016\/j.amjcard.2022.04.005","type":"journal-article","created":{"date-parts":[[2022,5,9]],"date-time":"2022-05-09T07:26:22Z","timestamp":1652081182000},"page":"8-18","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Relation of Extracardiac Vascular Disease and Outcomes in Patients With Diabetes (1.1 Million) Hospitalized for Acute Myocardial Infarction"],"prefix":"10.1016","volume":"175","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7572-8552","authenticated-orcid":false,"given":"Sedralmontaha","family":"Istanbuly","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9272-6906","authenticated-orcid":false,"given":"Andrija","family":"Matetic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Derek J.","family":"Roberts","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3852-6158","authenticated-orcid":false,"given":"Phyo K.","family":"Myint","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M Chadi","family":"Alraies","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8370-4569","authenticated-orcid":false,"given":"Harriette GC","family":"Van Spall","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9678-5222","authenticated-orcid":false,"given":"Mohamed O.","family":"Mohamed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aditya","family":"Bharadwaj","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9241-8890","authenticated-orcid":false,"given":"Mamas A.","family":"Mamas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.amjcard.2022.04.005_bib0001","doi-asserted-by":"crossref","first-page":"14790","DOI":"10.1038\/s41598-020-71908-9","article-title":"Global, regional, and national burden and trend of diabetes in 195 countries and territories: an analysis from 1990 to 2025","volume":"10","author":"Lin","year":"2020","journal-title":"Sci Rep"},{"key":"10.1016\/j.amjcard.2022.04.005_bib0002","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1111\/dom.14326","article-title":"Impact of polyvascular disease with and without co-existent kidney dysfunction on cardiovascular outcomes in diabetes: a post hoc analysis of EMPA-REG OUTCOME","volume":"23","author":"Verma","year":"2021","journal-title":"Diabetes Obes Metab"},{"key":"10.1016\/j.amjcard.2022.04.005_bib0003","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1016\/S2213-8587(18)30290-0","article-title":"Polyvascular disease, type 2 diabetes, and long-term vascular risk: a secondary analysis of the IMPROVE-IT trial","volume":"6","author":"Bonaca","year":"2018","journal-title":"Lancet Diabetes Endocrinol"},{"key":"10.1016\/j.amjcard.2022.04.005_bib0004","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0223215","article-title":"Outcomes of acute coronary syndrome patients with concurrent extra-cardiac vascular disease in the era of transradial coronary intervention: a retrospective multicenter cohort study","volume":"14","author":"Kodaira","year":"2019","journal-title":"PLoS One"},{"key":"10.1016\/j.amjcard.2022.04.005_bib0005","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ijcard.2020.11.051","article-title":"Impact of pre-existent vascular and poly-vascular disease on acute myocardial infarction management and outcomes: an analysis of 2 million patients from the National Inpatient Sample","volume":"327","author":"Kobo","year":"2021","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.amjcard.2022.04.005_bib0006","unstructured":"Agency for Healthcare Research and Quality. Healthcare Cost and Utilization Project: Overview of National (Nationwide) Inpatient Sample (NIS). Available at: http:\/\/www.hcup-us.ahrq.gov\/nisoverview.jsp. Accessed on January 25, 2022."},{"key":"10.1016\/j.amjcard.2022.04.005_bib0007","doi-asserted-by":"crossref","first-page":"4343","DOI":"10.1210\/jc.2017-01922","article-title":"Diabetic microvascular disease: an Endocrine Society scientific statement","volume":"102","author":"Barrett","year":"2017","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.amjcard.2022.04.005_bib0008","doi-asserted-by":"crossref","first-page":"77","DOI":"10.2337\/diaclin.26.2.77","article-title":"Microvascular and macrovascular complications of diabetes","volume":"26","author":"Fowler","year":"2008","journal-title":"Clin Diabetes"},{"key":"10.1016\/j.amjcard.2022.04.005_bib0009","doi-asserted-by":"crossref","first-page":"1816","DOI":"10.3390\/ijms19061816","article-title":"Diabetic retinopathy: pathophysiology and treatments","volume":"19","author":"Wang","year":"2018","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.amjcard.2022.04.005_bib0010","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.1007\/BF00400804","article-title":"Impaired blood flow and arterio-venous shunting in human diabetic neuropathy: a novel technique of nerve photography and fluorescein angiography","volume":"36","author":"Tesfaye","year":"1993","journal-title":"Diabetologia"},{"key":"10.1016\/j.amjcard.2022.04.005_bib0011","doi-asserted-by":"crossref","first-page":"961","DOI":"10.4239\/wjd.v6.i7.961","article-title":"Peripheral artery disease in patients with diabetes: epidemiology, mechanisms, and outcomes","volume":"6","author":"Thiruvoipati","year":"2015","journal-title":"World J Diabetes"},{"key":"10.1016\/j.amjcard.2022.04.005_bib0012","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1111\/j.2040-1124.2010.00070.x","article-title":"Mechanism of diabetic neuropathy: where are we now and where to go?","volume":"2","author":"Yagihashi","year":"2011","journal-title":"J Diabetes Investig"},{"key":"10.1016\/j.amjcard.2022.04.005_bib0013","doi-asserted-by":"crossref","first-page":"1296","DOI":"10.1016\/j.neuron.2017.02.005","article-title":"New horizons in diabetic neuropathy: mechanisms, bioenergetics, and pain","volume":"93","author":"Feldman","year":"2017","journal-title":"Neuron"},{"key":"10.1016\/j.amjcard.2022.04.005_bib0014","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1038\/s41572-019-0092-1","article-title":"Diabetic neuropathy","volume":"5","author":"Feldman","year":"2019","journal-title":"Nat Rev Dis Primers"},{"key":"10.1016\/j.amjcard.2022.04.005_bib0015","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4196\/kjpp.2014.18.1.1","article-title":"Advanced glycation end products and diabetic complications","volume":"18","author":"Singh","year":"2014","journal-title":"Korean J Physiol Pharmacol"},{"key":"10.1016\/j.amjcard.2022.04.005_bib0016","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1186\/s12872-020-01763-z","article-title":"Diabetic retinopathy predicts cardiovascular mortality in diabetes: a meta-analysis","volume":"20","author":"Xu","year":"2020","journal-title":"BMC Cardiovasc Disord"},{"key":"10.1016\/j.amjcard.2022.04.005_bib0017","first-page":"2889","article-title":"Diabetes and diabetic retinopathy are associated with impaired myocardial function in patients with cardiomyopathy","volume":"58","author":"Choi","year":"2017","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.amjcard.2022.04.005_bib0018","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCINTERVENTIONS.118.006400","article-title":"Outcomes after percutaneous coronary intervention in patients with a history of cerebrovascular disease: insights from the blue cross Blue Shield of Michigan Cardiovascular Consortium","volume":"11","author":"Song","year":"2018","journal-title":"Circ Cardiovasc Interv"},{"key":"10.1016\/j.amjcard.2022.04.005_bib0019","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1586\/erc.12.78","article-title":"Stroke in patients undergoing coronary angiography and percutaneous coronary intervention: incidence, predictors, outcome and therapeutic options","volume":"10","author":"Werner","year":"2012","journal-title":"Expert Rev Cardiovasc Ther"},{"key":"10.1016\/j.amjcard.2022.04.005_bib0020","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1111\/eci.12222","article-title":"The impact of polyvascular disease on long-term outcome in percutaneous coronary intervention patients","volume":"44","author":"van der Meer","year":"2014","journal-title":"Eur J Clin Invest"},{"key":"10.1016\/j.amjcard.2022.04.005_bib0021","doi-asserted-by":"crossref","first-page":"1736","DOI":"10.1016\/j.jacc.2013.01.054","article-title":"Association Between advanced age and vascular disease in different arterial territories: a population database of Over 3.6 million subjects","volume":"61","author":"Savji","year":"2013","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.amjcard.2022.04.005_bib0022","doi-asserted-by":"crossref","DOI":"10.1177\/1076029621996810","article-title":"Oral anticoagulant and antiplatelet therapy for peripheral arterial disease: a meta-analysis of randomized controlled trials","volume":"27","author":"Tang","year":"2021","journal-title":"Clin Appl Thromb Hemost"},{"key":"10.1016\/j.amjcard.2022.04.005_bib0023","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1161\/CIRCINTERVENTIONS.114.001306","article-title":"Access site complications after peripheral vascular interventions: incidence, predictors, and outcomes","volume":"7","author":"Ortiz","year":"2014","journal-title":"Circ Cardiovasc Interv"},{"key":"10.1016\/j.amjcard.2022.04.005_bib0024","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1186\/1471-2261-5-14","article-title":"The morbidity and mortality following a diagnosis of peripheral arterial disease: long-term follow-up of a large database","volume":"5","author":"Caro","year":"2005","journal-title":"BMC Cardiovasc Disord"},{"key":"10.1016\/j.amjcard.2022.04.005_bib0025","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1016\/j.ijcard.2012.11.033","article-title":"Peripheral artery disease and outcomes after myocardial infarction: an individual-patient meta-analysis of 28,771 patients in Capricorn, EPEHESUS, OPTIMAAL and VALIANT","volume":"168","author":"Inglis","year":"2013","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.amjcard.2022.04.005_bib0026","first-page":"e596","article-title":"2019 ACC\/AHA guideline on the primary prevention of cardiovascular disease: a report of the American College of Cardiology\/American Heart Association Task Force on clinical practice guidelines","volume":"140","author":"Arnett","year":"2019","journal-title":"Circulation"},{"key":"10.1016\/j.amjcard.2022.04.005_bib0027","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1093\/eurheartj\/ehz486","article-title":"ESC Scientific Document Group. 2019 ESC Guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD","volume":"41","author":"Cosentino","year":"2020","journal-title":"Eur Heart J"},{"key":"10.1016\/j.amjcard.2022.04.005_bib0028","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1002\/pds.4690","article-title":"Diagnostic accuracy of the International Classification of Diseases, tenth revision, codes of heart failure in an administrative database","volume":"28","author":"Bosco-L\u00e9vy","year":"2019","journal-title":"Pharmacoepidemiol Drug Saf"},{"key":"10.1016\/j.amjcard.2022.04.005_bib0029","doi-asserted-by":"crossref","first-page":"1424","DOI":"10.1111\/j.1475-6773.2007.00822.x","article-title":"Assessing validity of ICD-9-CM and ICD-10 administrative data in recording clinical conditions in a unique dually coded database","volume":"43","author":"Quan","year":"2008","journal-title":"Health Serv Res"}],"container-title":["The American Journal of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002914922003988?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002914922003988?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T06:42:15Z","timestamp":1757572935000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002914922003988"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7]]},"references-count":29,"alternative-id":["S0002914922003988"],"URL":"https:\/\/doi.org\/10.1016\/j.amjcard.2022.04.005","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.742140269.793595026","asserted-by":"object"}]},"ISSN":["0002-9149"],"issn-type":[{"value":"0002-9149","type":"print"}],"subject":[],"published":{"date-parts":[[2022,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Relation of Extracardiac Vascular Disease and Outcomes in Patients With Diabetes (1.1 Million) Hospitalized for Acute Myocardial Infarction","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.amjcard.2022.04.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}