{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T07:55:34Z","timestamp":1770969334474,"version":"3.50.1"},"reference-count":29,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,6,18]],"date-time":"2023-06-18T00:00:00Z","timestamp":1687046400000},"content-version":"am","delay-in-days":321,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100008497","name":"Boston Scientific Corporation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008497","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["HL077478"],"award-info":[{"award-number":["HL077478"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["TL1 TR002000"],"award-info":[{"award-number":["TL1 TR002000"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008091","name":"University of Rochester","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008091","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["ajconline.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Cardiology"],"published-print":{"date-parts":[[2022,8]]},"DOI":"10.1016\/j.amjcard.2022.04.027","type":"journal-article","created":{"date-parts":[[2022,5,20]],"date-time":"2022-05-20T08:19:50Z","timestamp":1653034790000},"page":"43-50","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Comparison of Frequency of Ventricular Tachyarrhythmia in Men-Versus-Women in Patients with Implantable Cardioverter-Defibrillator for Primary Prevention"],"prefix":"10.1016","volume":"176","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6082-535X","authenticated-orcid":false,"given":"Amole","family":"Ojo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arwa","family":"Younis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shireen","family":"Saxena","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valentina","family":"Kutyifa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anita Y.","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Scott","family":"McNitt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bronislava","family":"Polonsky","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehmet K.","family":"Aktas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David T.","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Spencer","family":"Rosero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Himabindu","family":"Vidula","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander","family":"Diamond","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ramya","family":"Sampath","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helmut","family":"Klein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hillel","family":"Steiner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wojciech","family":"Zareba","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ilan","family":"Goldenberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.amjcard.2022.04.027_bib0001","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1056\/NEJMoa043399","article-title":"Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT) Investigators. Amiodarone or an implantable cardioverter-defibrillator for congestive heart failure","volume":"352","author":"Bardy","year":"2005","journal-title":"N Engl J Med"},{"key":"10.1016\/j.amjcard.2022.04.027_bib0002","doi-asserted-by":"crossref","first-page":"1882","DOI":"10.1056\/NEJM199912163412503","article-title":"A randomized study of the prevention of sudden death in patients with coronary artery disease. Multicenter unsustained tachycardia Trial Investigators","volume":"341","author":"Buxton","year":"1999","journal-title":"N Engl J Med"},{"key":"10.1016\/j.amjcard.2022.04.027_bib0003","doi-asserted-by":"crossref","first-page":"2151","DOI":"10.1056\/NEJMoa033088","article-title":"Defibrillators in Nonischemic Cardiomyopathy Treatment Evaluation (DEFINITE) Investigators. Prophylactic defibrillator implantation in patients with nonischemic dilated cardiomyopathy","volume":"350","author":"Kadish","year":"2004","journal-title":"N Engl J Med"},{"key":"10.1016\/j.amjcard.2022.04.027_bib0004","doi-asserted-by":"crossref","first-page":"1933","DOI":"10.1056\/NEJM199612263352601","article-title":"Improved survival with an implanted defibrillator in patients with coronary disease at high risk for ventricular arrhythmia. Multicenter Automatic Defibrillator Implantation Trial Investigators","volume":"335","author":"Moss","year":"1996","journal-title":"N Engl J Med"},{"key":"10.1016\/j.amjcard.2022.04.027_bib0005","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1056\/NEJMoa0906431","article-title":"MADIT-CRT Trial Investigators. Cardiac-resynchronization therapy for the prevention of heart-failure events","volume":"361","author":"Moss","year":"2009","journal-title":"N Engl J Med"},{"key":"10.1016\/j.amjcard.2022.04.027_bib0006","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1056\/NEJMoa013474","article-title":"Multicenter Automatic Defibrillator Implantation Trial II Investigators. Prophylactic implantation of a defibrillator in patients with myocardial infarction and reduced ejection fraction","volume":"346","author":"Moss","year":"2002","journal-title":"N Engl J Med"},{"key":"10.1016\/j.amjcard.2022.04.027_bib0007","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0162756","article-title":"Gender differences in appropriate shocks and mortality among patients with primary prophylactic implantable cardioverter-defibrillators: systematic review and meta-analysis","volume":"11","author":"Conen","year":"2016","journal-title":"PLoS ONE"},{"key":"10.1016\/j.amjcard.2022.04.027_bib0008","doi-asserted-by":"crossref","first-page":"195","DOI":"10.7326\/0003-4819-156-3-201202070-00007","article-title":"Sex differences in implantable cardioverter-defibrillator outcomes: findings from a prospective defibrillator database","volume":"156","author":"MacFadden","year":"2012","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.amjcard.2022.04.027_bib0009","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1016\/j.hlc.2019.07.017","article-title":"Sex differences in electrophysiology, ventricular tachyarrhythmia, cardiac arrest and sudden cardiac death following acute myocardial infarction","volume":"29","author":"Zaman","year":"2020","journal-title":"Heart Lung Circ"},{"key":"10.1016\/j.amjcard.2022.04.027_bib0010","unstructured":"Zareba W. Risk Stratification in MADIT II Type Patients; 2011."},{"key":"10.1016\/j.amjcard.2022.04.027_bib0011","doi-asserted-by":"crossref","first-page":"2275","DOI":"10.1056\/NEJMoa1211107","article-title":"MADIT-RIT Trial Investigators. Reduction in inappropriate therapy and mortality through ICD programming","volume":"367","author":"Moss","year":"2012","journal-title":"N Engl J Med"},{"key":"10.1016\/j.amjcard.2022.04.027_bib0012","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/j.ahj.2008.02.026","article-title":"DEFINITE Investigators. Sex differences in outcome after implantable cardioverter defibrillator implantation in nonischemic cardiomyopathy","volume":"156","author":"Albert","year":"2008","journal-title":"Am Heart J"},{"key":"10.1016\/j.amjcard.2022.04.027_bib0013","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1111\/j.1540-8167.2008.01129.x","article-title":"Primary prevention with defibrillator therapy in women: results from the sudden cardiac death in Heart Failure Trial","volume":"19","author":"Russo","year":"2008","journal-title":"J Cardiovasc Electrophysiol"},{"key":"10.1016\/j.amjcard.2022.04.027_bib0014","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1136\/heartjnl-2013-304013","article-title":"Gender-specific differences in clinical outcome of primary prevention implantable cardioverter defibrillator recipients","volume":"99","author":"van der Heijden","year":"2013","journal-title":"Heart"},{"key":"10.1016\/j.amjcard.2022.04.027_bib0015","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1016\/j.hrthm.2010.03.042","article-title":"Gender differences in clinical outcome and primary prevention defibrillator benefit in patients with severe left ventricular dysfunction: a systematic review and meta-analysis","volume":"7","author":"Santangeli","year":"2010","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.amjcard.2022.04.027_bib0016","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1016\/j.hrthm.2013.01.003","article-title":"Cardiac MRI scar patterns differ by sex in an implantable cardioverter-defibrillator and cardiac resynchronization therapy cohort","volume":"10","author":"Loring","year":"2013","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.amjcard.2022.04.027_bib0017","doi-asserted-by":"crossref","first-page":"1440","DOI":"10.1093\/europace\/euv313","article-title":"Sex-dependent alterations of Ca2+ cycling in human cardiac hypertrophy and heart failure","volume":"18","author":"Fischer","year":"2016","journal-title":"Europace"},{"key":"10.1016\/j.amjcard.2022.04.027_bib0018","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1210\/en.2003-0816","article-title":"Androgen contributes to gender-related cardiac hypertrophy and fibrosis in mice lacking the gene encoding guanylyl cyclase-A","volume":"145","author":"Li","year":"2004","journal-title":"Endocrinology"},{"key":"10.1016\/j.amjcard.2022.04.027_bib0019","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1016\/j.ejheart.2008.07.002","article-title":"Non-sustained ventricular tachycardia as a predictor of sudden cardiac death in patients with left ventricular dysfunction: a meta-analysis","volume":"10","author":"de Sousa","year":"2008","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.amjcard.2022.04.027_bib0020","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1111\/j.1540-8159.2009.02566.x","article-title":"Predictors of appropriate implantable cardioverter defibrillator (ICD) therapy in primary prevention patients with ischemic and nonischemic cardiomyopathy","volume":"33","author":"Verma","year":"2010","journal-title":"Pacing Clin Electrophysiol"},{"key":"10.1016\/j.amjcard.2022.04.027_bib0021","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1161\/01.CIR.84.1.40","article-title":"Prognostic significance of atrial fibrillation in advanced heart failure. A study of 390 patients","volume":"84","author":"Middlekauff","year":"1991","journal-title":"Circulation"},{"key":"10.1016\/j.amjcard.2022.04.027_bib0022","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1016\/j.jelectrocard.2014.07.023","article-title":"Racial differences in sudden cardiac death","volume":"47","author":"Fender","year":"2014","journal-title":"J Electrocardiol"},{"key":"10.1016\/j.amjcard.2022.04.027_bib0023","doi-asserted-by":"crossref","unstructured":"Zhao D, Post WS, Blasco-Colmenares E, Cheng A, Zhang Y, DEO, Deo R, Pastor-Barriuso R, Michos ED, Sotoodehnia N, Guallar E. Racial differences in sudden cardiac death. Circulation Sotoodehnia N, Guallar E, ed. 2019;139:1688\u20131697.","DOI":"10.1161\/CIRCULATIONAHA.118.036553"},{"key":"10.1016\/j.amjcard.2022.04.027_bib0024","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1016\/j.hrthm.2004.07.013","article-title":"Spectrum and prevalence of cardiac sodium channel variants among Black, White, Asian, and Hispanic individuals: implications for arrhythmogenic susceptibility and Brugada\/long QT syndrome genetic testing","volume":"1","author":"Ackerman","year":"2004","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.amjcard.2022.04.027_bib0025","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.4065\/78.12.1479","article-title":"Ethnic differences in cardiac potassium channel variants: implications for genetic susceptibility to sudden cardiac death and genetic testing for congenital long QT syndrome","volume":"78","author":"Ackerman","year":"2003","journal-title":"Mayo Clin Proc"},{"key":"10.1016\/j.amjcard.2022.04.027_bib0026","doi-asserted-by":"crossref","unstructured":"Akylbekova EL, Payne JP, Newton-Cheh C, May WL, Fox ER, Wilson JG, Sarpong DF, Taylor HA, Maher JF. Gene-environment interaction between SCN5A-1103Y and hypokalemia influences QT interval prolongation in African Americans: the Jackson Heart Study. Am Heart J2014;167:116\u2013122.e1.","DOI":"10.1016\/j.ahj.2013.10.009"},{"key":"10.1016\/j.amjcard.2022.04.027_bib0027","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1161\/CIRCULATIONAHA.104.482760","article-title":"Role of SCN5A Y1102 polymorphism in sudden cardiac death in blacks","volume":"112","author":"Burke","year":"2005","journal-title":"Circulation"},{"key":"10.1016\/j.amjcard.2022.04.027_bib0028","doi-asserted-by":"crossref","first-page":"1722","DOI":"10.1016\/j.amjcard.2006.01.032","article-title":"Gender differences of revascularization in patients with acute myocardial infarction","volume":"97","author":"Fang","year":"2006","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.amjcard.2022.04.027_bib0029","doi-asserted-by":"crossref","first-page":"1961","DOI":"10.1016\/j.jacc.2015.08.865","article-title":"Temporal trends and sex differences in revascularization and outcomes of ST-segment elevation myocardial infarction in younger adults in the United States","volume":"66","author":"Khera","year":"2015","journal-title":"J Am Coll Cardiol"}],"container-title":["The American Journal of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002914922004325?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002914922004325?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T06:42:59Z","timestamp":1757572979000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002914922004325"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8]]},"references-count":29,"alternative-id":["S0002914922004325"],"URL":"https:\/\/doi.org\/10.1016\/j.amjcard.2022.04.027","relation":{},"ISSN":["0002-9149"],"issn-type":[{"value":"0002-9149","type":"print"}],"subject":[],"published":{"date-parts":[[2022,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Comparison of Frequency of Ventricular Tachyarrhythmia in Men-Versus-Women in Patients with Implantable Cardioverter-Defibrillator for Primary Prevention","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.amjcard.2022.04.027","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}