{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T05:15:10Z","timestamp":1784870110097,"version":"3.55.0"},"reference-count":16,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["5T32HL7381"],"award-info":[{"award-number":["5T32HL7381"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["ajconline.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Cardiology"],"published-print":{"date-parts":[[2023,9]]},"DOI":"10.1016\/j.amjcard.2023.06.022","type":"journal-article","created":{"date-parts":[[2023,7,4]],"date-time":"2023-07-04T00:26:40Z","timestamp":1688430400000},"page":"12-16","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":28,"special_numbering":"C","title":["How Often Does Apical Sparing of Longitudinal Strain Indicate the Presence of Cardiac Amyloidosis?"],"prefix":"10.1016","volume":"202","author":[{"given":"Eisha","family":"Wali","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Gruca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristiane","family":"Singulane","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Cotella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brittney","family":"Guile","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roydell","family":"Johnson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7932-6473","authenticated-orcid":false,"given":"Victor","family":"Mor-Avi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karima","family":"Addetia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto M.","family":"Lang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.amjcard.2023.06.022_bib0001","first-page":"e7","article-title":"Cardiac amyloidosis: evolving diagnosis and management: a scientific statement from the American Heart Association [published correction appears in Circulation. 2021;144:e10] [published correction appears in Circulation. 2021;144:e11]","volume":"142","author":"Kittleson","year":"2020","journal-title":"Circulation"},{"key":"10.1016\/j.amjcard.2023.06.022_bib0002","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1111\/bjh.16143","article-title":"A 24-year experience of autologous stem cell transplantation for light chain amyloidosis patients in the United Kingdom","volume":"187","author":"Sharpley","year":"2019","journal-title":"Br J Haematol"},{"key":"10.1016\/j.amjcard.2023.06.022_bib0003","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1056\/NEJMoa1805689","article-title":"Tafamidis treatment for patients with transthyretin amyloid cardiomyopathy","volume":"379","author":"Maurer","year":"2018","journal-title":"N Engl J Med"},{"key":"10.1016\/j.amjcard.2023.06.022_bib0004","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1148\/rg.2020190069","article-title":"Trends in diagnostic imaging of cardiac amyloidosis: emerging knowledge and concepts","volume":"40","author":"Oda","year":"2020","journal-title":"Radiographics"},{"key":"10.1016\/j.amjcard.2023.06.022_bib0005","doi-asserted-by":"crossref","first-page":"1442","DOI":"10.1136\/heartjnl-2012-302353","article-title":"Relative apical sparing of longitudinal strain using two-dimensional speckle-tracking echocardiography is both sensitive and specific for the diagnosis of cardiac amyloidosis","volume":"98","author":"Phelan","year":"2012","journal-title":"Heart"},{"key":"10.1016\/j.amjcard.2023.06.022_bib0006","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.1016\/j.jacc.2022.11.022","article-title":"2023 ACC Expert Consensus decision pathway on comprehensive multidisciplinary care for the patient with cardiac amyloidosis: A report of the American College of Cardiology solution set oversight committee","volume":"81","author":"Committee","year":"2023","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.amjcard.2023.06.022_bib0007","doi-asserted-by":"crossref","first-page":"1288","DOI":"10.1016\/j.jacc.2022.01.036","article-title":"Critical comparison of documents from scientific societies on cardiac amyloidosis: JACC State-of-the-Art Review","volume":"79","author":"Rapezzi","year":"2022","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.amjcard.2023.06.022_bib0008","article-title":"Role of cardiovascular imaging for the diagnosis and prognosis of cardiac amyloidosis","volume":"5","author":"Agha","year":"2018","journal-title":"Open Hear"},{"key":"10.1016\/j.amjcard.2023.06.022_bib0009","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1186\/s12947-021-00258-x","article-title":"Cardiac amyloidosis screening using a relative apical sparing pattern in patients with left ventricular hypertrophy","volume":"19","author":"Nakao","year":"2021","journal-title":"Cardiovasc Ultrasound"},{"key":"10.1016\/j.amjcard.2023.06.022_bib0010","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1016\/j.recesp.2020.04.014","article-title":"Left ventricle myocardial deformation pattern in severe aortic valve stenosis without cardiac amyloidosis. The AMY-TAVI trial","volume":"73","author":"Bastos Fern\u00e1ndez","year":"2020","journal-title":"Rev Esp Cardiol (Engl Ed)"},{"key":"10.1016\/j.amjcard.2023.06.022_bib0011","doi-asserted-by":"crossref","unstructured":"Abecasis J, Lopes P, Santos RR, Malt\u00eas S, Guerreiro S, Ferreira A, Freitas P, Ribeiras R, Andrade MJ, Manso RT, Ramos S, Gil V, Masci PG, Cardim N. Prevalence and significance of relative apical sparing in aortic stenosis: insights from an echo and cardiovascular magnetic resonance study of patients referred for surgical aortic valve replacement [published online February 26, 2023]. Eur Hear J Cardiovasc Imaging doi:10.1093\/ehjci\/jead032.","DOI":"10.1093\/ehjci\/jead032"},{"key":"10.1016\/j.amjcard.2023.06.022_bib0012","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1016\/j.jcmg.2018.06.016","article-title":"Relative apical sparing of myocardial longitudinal strain is explained by regional differences in total amyloid mass rather than the proportion of amyloid deposits","volume":"12","author":"Bravo","year":"2019","journal-title":"JACC Cardiovasc Imaging"},{"key":"10.1016\/j.amjcard.2023.06.022_bib0013","doi-asserted-by":"crossref","first-page":"e45","DOI":"10.1161\/CIRCHEARTFAILURE.113.000432","article-title":"Apical sparing of longitudinal strain, left ventricular rotational abnormalities, and short-axis dysfunction in primary hyperoxaluria Type 1","volume":"6","author":"Lagies","year":"2013","journal-title":"Circ Heart Fail"},{"key":"10.1016\/j.amjcard.2023.06.022_bib0014","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1016\/j.jaccas.2020.02.018","article-title":"Apical sparing pattern of longitudinal strain and positive bone scintigraphy in metastatic myocardial calcification","volume":"2","author":"Zhang","year":"2020","journal-title":"JACC Case Rep"},{"key":"10.1016\/j.amjcard.2023.06.022_bib0015","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.121.022544","article-title":"Myocardial strain and association with clinical outcomes in Danon disease: a model for monitoring progression of genetic cardiomyopathies","volume":"10","author":"Bui","year":"2021","journal-title":"J Am Heart Assoc"},{"key":"10.1016\/j.amjcard.2023.06.022_bib0016","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCHEARTFAILURE.119.006075","article-title":"Expert consensus recommendations for the suspicion and diagnosis of transthyretin cardiac amyloidosis","volume":"12","author":"Maurer","year":"2019","journal-title":"Circ Heart Fail"}],"container-title":["The American Journal of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002914923004009?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002914923004009?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T06:46:42Z","timestamp":1757573202000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002914923004009"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9]]},"references-count":16,"alternative-id":["S0002914923004009"],"URL":"https:\/\/doi.org\/10.1016\/j.amjcard.2023.06.022","relation":{},"ISSN":["0002-9149"],"issn-type":[{"value":"0002-9149","type":"print"}],"subject":[],"published":{"date-parts":[[2023,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"How Often Does Apical Sparing of Longitudinal Strain Indicate the Presence of Cardiac Amyloidosis?","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.amjcard.2023.06.022","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}