{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T18:45:44Z","timestamp":1767033944952,"version":"3.44.0"},"reference-count":15,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,6,9]],"date-time":"2023-06-09T00:00:00Z","timestamp":1686268800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["ajconline.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Cardiology"],"published-print":{"date-parts":[[2023,8]]},"DOI":"10.1016\/j.amjcard.2023.06.032","type":"journal-article","created":{"date-parts":[[2023,7,3]],"date-time":"2023-07-03T13:34:55Z","timestamp":1688391295000},"page":"328-334","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Virtual Echocardiography Screening Tool Identifies Pulmonary Arterial Hypertension Significantly Earlier Than High-Risk Clinical Diagnosis"],"prefix":"10.1016","volume":"201","author":[{"given":"Natasha A.","family":"Vedage","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul R.","family":"Forfia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander","family":"Grafstrom","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6513-4112","authenticated-orcid":false,"given":"Anjali","family":"Vaidya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.amjcard.2023.06.032_bib0001","doi-asserted-by":"crossref","first-page":"3618","DOI":"10.1093\/eurheartj\/ehac237","article-title":"2022 ESC\/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension","volume":"43","author":"Humbert","year":"2022","journal-title":"Eur Heart J"},{"key":"10.1016\/j.amjcard.2023.06.032_bib0002","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/j.chest.2019.02.004","article-title":"Predicting survival in patients with pulmonary arterial hypertension: the REVEAL risk score calculator 2.0 and comparison with ESC\/ERS-based risk assessment strategies","volume":"156","author":"Benza","year":"2019","journal-title":"Chest"},{"key":"10.1016\/j.amjcard.2023.06.032_bib0003","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1183\/09059180.00005112","article-title":"Early detection and management of pulmonary arterial hypertension","volume":"21","author":"Humbert","year":"2012","journal-title":"Eur Respir Rev"},{"key":"10.1016\/j.amjcard.2023.06.032_bib0004","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1164\/rccm.201004-0601OC","article-title":"Shape of the right ventricular Doppler envelope predicts hemodynamics and right heart function in pulmonary hypertension","volume":"183","author":"Arkles","year":"2011","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.amjcard.2023.06.032_bib0005","doi-asserted-by":"crossref","first-page":"1584","DOI":"10.1111\/echo.13699","article-title":"Differences in right ventricular morphology, not function, indicate the nature of increased afterload in pulmonary hypertensive subjects with normal left ventricular function","volume":"34","author":"Raza","year":"2017","journal-title":"Echocardiography"},{"key":"10.1016\/j.amjcard.2023.06.032_bib0006","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1161\/CIRCIMAGING.112.976654","article-title":"A simple echocardiographic prediction rule for hemodynamics in pulmonary hypertension","volume":"5","author":"Opotowsky","year":"2012","journal-title":"Circ Cardiovasc Imaging"},{"key":"10.1016\/j.amjcard.2023.06.032_bib0007","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1177\/2045894020950225","article-title":"Virtual echocardiography screening tool to differentiate hemodynamic profiles in pulmonary hypertension","volume":"10","author":"Vaidya","year":"2020","journal-title":"Pulm Circ"},{"key":"10.1016\/j.amjcard.2023.06.032_bib0008","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1183\/13993003.01913-2018","article-title":"Haemodynamic definitions and updated clinical classification of pulmonary hypertension","volume":"53","author":"Simonneau","year":"2019","journal-title":"Eur Respir J"},{"key":"10.1016\/j.amjcard.2023.06.032_bib0009","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1378\/chest.09-1140","article-title":"Pulmonary arterial hypertension: baseline characteristics from the REVEAL registry","volume":"137","author":"Badesch","year":"2010","journal-title":"Chest"},{"key":"10.1016\/j.amjcard.2023.06.032_bib0010","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1378\/chest.10-1166","article-title":"Delay in recognition of pulmonary arterial hypertension: factors identified from the REVEAL registry","volume":"140","author":"Brown","year":"2011","journal-title":"Chest"},{"key":"10.1016\/j.amjcard.2023.06.032_bib0011","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1016\/j.amjcard.2013.05.016","article-title":"A simple echocardiographic method to estimate pulmonary vascular resistance","volume":"112","author":"Opotowsky","year":"2013","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.amjcard.2023.06.032_bib0012","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1164\/rccm.200806-953OC","article-title":"Connective tissue disease-associated pulmonary arterial hypertension in the modern treatment era","volume":"179","author":"Condliffe","year":"2009","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.amjcard.2023.06.032_bib0013","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1183\/09031936.00057010","article-title":"Survival in incident and prevalent cohorts of patients with pulmonary arterial hypertension","volume":"36","author":"Humbert","year":"2010","journal-title":"Eur Respir J"},{"key":"10.1016\/j.amjcard.2023.06.032_bib0014","doi-asserted-by":"crossref","first-page":"33","DOI":"10.3390\/diseases6020033","article-title":"Comparison of brain natriuretic peptide levels to simultaneously obtained right heart hemodynamics in stable outpatients with pulmonary arterial hypertension","volume":"6","author":"Helgeson","year":"2018","journal-title":"Diseases"},{"key":"10.1016\/j.amjcard.2023.06.032_bib0015","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1093\/eurheartj\/ehv317","article-title":"2015 ESC\/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension","volume":"37","author":"Gali\u00e8","year":"2016","journal-title":"Eur Heart J"}],"container-title":["The American Journal of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002914923004022?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002914923004022?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T06:49:40Z","timestamp":1757573380000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002914923004022"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8]]},"references-count":15,"alternative-id":["S0002914923004022"],"URL":"https:\/\/doi.org\/10.1016\/j.amjcard.2023.06.032","relation":{},"ISSN":["0002-9149"],"issn-type":[{"type":"print","value":"0002-9149"}],"subject":[],"published":{"date-parts":[[2023,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Virtual Echocardiography Screening Tool Identifies Pulmonary Arterial Hypertension Significantly Earlier Than High-Risk Clinical Diagnosis","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.amjcard.2023.06.032","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Author(s). Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}