{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,11]],"date-time":"2026-11-11T01:26:37Z","timestamp":1794360397068,"version":"4.9.0"},"reference-count":31,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["ajconline.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Cardiology"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1016\/j.amjcard.2026.09.028","type":"journal-article","created":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T14:16:00Z","timestamp":1791123360000},"page":"118-124","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Left Atrial Appendage Occlusion Among Cancer Patients With Atrial Fibrillation: A Systematic Review and Updated Meta-Analysis"],"prefix":"10.1016","volume":"280","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-6992-4641","authenticated-orcid":false,"given":"Luisalice Mendes","family":"Afonso","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-3650-4895","authenticated-orcid":false,"given":"Giuseppe De Bacco","family":"Gava","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-1537-8528","authenticated-orcid":false,"given":"Hemilly da Silva","family":"Pires","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-6945-6676","authenticated-orcid":false,"given":"Ezequiel Freire","family":"Fiuza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-1011-086X","authenticated-orcid":false,"given":"Bernardo Temer Teixeira","family":"Goldwasser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-8299-6332","authenticated-orcid":false,"given":"Marcelo","family":"Rogelin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7405-1789","authenticated-orcid":false,"given":"Edielle de Sant Anna","family":"Melo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.amjcard.2026.09.028_bib0001","article-title":"Practical guide on left atrial appendage closure for the non-implanting physician: an international consensus paper","volume":"26","author":"Potpara","year":"2024","journal-title":"Europace"},{"issue":"1","key":"10.1016\/j.amjcard.2026.09.028_bib0002","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1161\/CIR.0000000000001193","article-title":"2023 ACC\/AHA\/ACCP\/HRS Guideline for the diagnosis and management of atrial fibrillation: a report of the American College of Cardiology\/American Heart Association Joint Committee on Clinical Practice Guidelines","volume":"149","author":"Joglar","year":"2024","journal-title":"Circulation"},{"issue":"15","key":"10.1016\/j.amjcard.2026.09.028_bib0003","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1136\/heartjnl-2012-301799","article-title":"Importance of the underlying substrate in determining thrombus location in atrial fibrillation: implications for left atrial appendage closure","volume":"98","author":"Mahajan","year":"2012","journal-title":"Heart"},{"issue":"19","key":"10.1016\/j.amjcard.2026.09.028_bib0004","doi-asserted-by":"crossref","first-page":"1988","DOI":"10.1001\/jama.2014.15192","article-title":"Percutaneous left atrial appendage closure vs warfarin for atrial fibrillation: a randomized clinical trial","volume":"312","author":"Reddy","year":"2014","journal-title":"JAMA"},{"issue":"25","key":"10.1016\/j.amjcard.2026.09.028_bib0005","doi-asserted-by":"crossref","first-page":"3122","DOI":"10.1016\/j.jacc.2020.04.067","article-title":"Left atrial appendage closure versus direct oral anticoagulants in high-risk patients with atrial fibrillation","volume":"75","author":"Osmancik","year":"2020","journal-title":"J Am Coll Cardiol"},{"issue":"13","key":"10.1016\/j.amjcard.2026.09.028_bib0006","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1056\/NEJMoa2513310","article-title":"Left atrial appendage closure or medical therapy in atrial fibrillation","volume":"394","author":"Landmesser","year":"2026","journal-title":"N Engl J Med"},{"issue":"21","key":"10.1016\/j.amjcard.2026.09.028_bib0007","doi-asserted-by":"crossref","first-page":"2083","DOI":"10.1056\/NEJMoa2517213","article-title":"Left atrial appendage closure or anticoagulation for atrial fibrillation","volume":"394","author":"Doshi","year":"2026","journal-title":"N Engl J Med"},{"issue":"1","key":"10.1016\/j.amjcard.2026.09.028_bib0008","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1186\/s12885-019-6314-9","article-title":"Incidence of atrial fibrillation in different major cancer subtypes: a nationwide population-based 12 year follow up study","volume":"19","author":"Jakobsen","year":"2019","journal-title":"BMC Cancer"},{"issue":"12","key":"10.1016\/j.amjcard.2026.09.028_bib0009","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1200\/JOP.18.00592","article-title":"Atrial fibrillation and stroke risk in patients with cancer: a primer for oncologists","volume":"15","author":"Sorigue","year":"2019","journal-title":"J Oncol Pract"},{"issue":"2","key":"10.1016\/j.amjcard.2026.09.028_bib0010","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.ijcard.2012.08.036","article-title":"Incident thromboembolism and heart failure associated with new-onset atrial fibrillation in cancer patients","volume":"165","author":"Hu","year":"2013","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.amjcard.2026.09.028_bib0011","doi-asserted-by":"crossref","first-page":"2","DOI":"10.4081\/cardio.2025.72","article-title":"Safety and efficacy of left atrial appendage closure in cancer versus non-cancer patients: a systematic review and meta-analysis","volume":"3","author":"Ahmed","year":"2025","journal-title":"Global Cardiol"},{"key":"10.1016\/j.amjcard.2026.09.028_bib0012","doi-asserted-by":"crossref","first-page":"n71","DOI":"10.1136\/bmj.n71","article-title":"The PRISMA 2020 statement: an updated guideline for reporting systematic reviews","volume":"372","author":"Page","year":"2021","journal-title":"BMJ"},{"key":"10.1016\/j.amjcard.2026.09.028_bib0013","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2024.108602","article-title":"A tool to assess risk of bias in non-randomized follow-up studies of exposure effects (ROBINS-E)","volume":"186","author":"Higgins","year":"2024","journal-title":"Environ Int"},{"key":"10.1016\/j.amjcard.2026.09.028_bib0014","unstructured":"-Gewehr D, Carvalho PEP. How to perform meta-analysis with R\u2014exploring heterogeneity: leave-one-out analysis. 2023."},{"key":"10.1016\/j.amjcard.2026.09.028_bib0015","series-title":"Doing Meta-Analysis With R: A Hands-On Guide","author":"Harrer","year":"2022"},{"issue":"8","key":"10.1016\/j.amjcard.2026.09.028_bib0016","doi-asserted-by":"crossref","first-page":"1791","DOI":"10.1007\/s10840-023-01621-w","article-title":"Outcomes of patients with cancer undergoing percutaneous left atrial appendage occlusion","volume":"66","author":"Agarwal","year":"2023","journal-title":"J Interv Card Electrophysiol"},{"issue":"11","key":"10.1016\/j.amjcard.2026.09.028_bib0017","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1016\/j.jcin.2019.04.002","article-title":"5-Year experience of in-hospital outcomes after percutaneous left atrial appendage closure in Germany","volume":"12","author":"Hobohm","year":"2019","journal-title":"JACC Cardiovasc Interv"},{"key":"10.1016\/j.amjcard.2026.09.028_bib0018","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.amjcard.2020.12.003","article-title":"Procedural and short-term outcomes of percutaneous left atrial appendage closure in patients with cancer","volume":"141","author":"Isogai","year":"2021","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.amjcard.2026.09.028_bib0019","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.amjcard.2023.06.068","article-title":"Left atrial appendage closure outcomes in patients with cancer at a single tertiary center","volume":"202","author":"Kumar","year":"2023","journal-title":"Am J Cardiol"},{"issue":"8","key":"10.1016\/j.amjcard.2026.09.028_bib0020","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.3390\/cancers17081331","article-title":"In-hospital outcomes of left atrial appendage occlusion among cancer patients with atrial fibrillation: a nationwide U.S. study","volume":"17","author":"Margolis","year":"2025","journal-title":"Cancers"},{"issue":"2","key":"10.1016\/j.amjcard.2026.09.028_bib0021","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.jaccao.2022.10.016","article-title":"Left atrial appendage occlusion in patients with atrial fibrillation and cancer","volume":"5","author":"Shabtaie","year":"2023","journal-title":"JACC CardioOncol"},{"issue":"21","key":"10.1016\/j.amjcard.2026.09.028_bib0022","doi-asserted-by":"crossref","first-page":"6514","DOI":"10.3390\/jcm13216514","article-title":"Left atrial appendage closure in atrial fibrillation patients with cancer","volume":"13","author":"Zweiker","year":"2024","journal-title":"J Clin Med"},{"key":"10.1016\/j.amjcard.2026.09.028_bib0023","article-title":"Short- and long-term outcomes of percutaneous left atrial appendage occlusion in cancer patients","volume":"56","author":"Tinoco","year":"2025","journal-title":"IJC Heart Vasc"},{"issue":"1","key":"10.1016\/j.amjcard.2026.09.028_bib0024","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1186\/s40959-023-00192-z","article-title":"Utilization and short-term outcomes of percutaneous left atrial appendage occlusion in patients with cancer","volume":"9","author":"Zhang","year":"2023","journal-title":"Cardio-oncology"},{"issue":"6","key":"10.1016\/j.amjcard.2026.09.028_bib0025","first-page":"829","article-title":"Assessment of the strength of recommendation and quality of evidence: GRADE checklist. A descriptive study","volume":"140","author":"Bezerra","year":"2022","journal-title":"Sao Paulo Med J"},{"issue":"2","key":"10.1016\/j.amjcard.2026.09.028_bib0026","doi-asserted-by":"crossref","DOI":"10.1111\/eci.14347","article-title":"Long-term risks and benefits of oral anticoagulation in atrial fibrillation patients with cancer: a report from the GLORIA-AF registry","volume":"55","author":"Li","year":"2025","journal-title":"Eur J Clin Invest"},{"issue":"2","key":"10.1016\/j.amjcard.2026.09.028_bib0027","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1007\/s11739-022-03156-w","article-title":"Bleeding and thrombotic events in atrial fibrillation patients with cancer: a systematic review and meta-analysis","volume":"18","author":"Pastori","year":"2023","journal-title":"Intern Emerg Med"},{"issue":"24","key":"10.1016\/j.amjcard.2026.09.028_bib0028","doi-asserted-by":"crossref","first-page":"7753","DOI":"10.3390\/jcm13247753","article-title":"Atrial fibrillation and cancer\u2014epidemiology, mechanisms, and management","volume":"13","author":"Davis","year":"2024","journal-title":"J Clin Med"},{"issue":"7","key":"10.1016\/j.amjcard.2026.09.028_bib0029","doi-asserted-by":"crossref","DOI":"10.1093\/europace\/euae188","article-title":"Incidence and predictors of 2-year mortality following percutaneous left atrial appendage occlusion in the EWOLUTION trial","volume":"26","author":"Aarnink","year":"2024","journal-title":"Europace"},{"issue":"7","key":"10.1016\/j.amjcard.2026.09.028_bib0030","doi-asserted-by":"crossref","DOI":"10.1111\/eci.13773","article-title":"Impact of malignancy on outcomes in European patients with atrial fibrillation: a report from the ESC-EHRA EURObservational research programme in atrial fibrillation general long-term registry","volume":"52","author":"Malavasi","year":"2022","journal-title":"Eur J Clin Invest"},{"issue":"5","key":"10.1016\/j.amjcard.2026.09.028_bib0031","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2022.14594","article-title":"Periprocedural outcomes associated with use of a left atrial appendage occlusion device in China","volume":"5","author":"Su","year":"2022","journal-title":"JAMA Netw Open"}],"container-title":["The American Journal of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002914926006004?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002914926006004?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,11,11]],"date-time":"2026-11-11T01:13:21Z","timestamp":1794359601000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002914926006004"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,12]]},"references-count":31,"alternative-id":["S0002914926006004"],"URL":"https:\/\/doi.org\/10.1016\/j.amjcard.2026.09.028","relation":{},"ISSN":["0002-9149"],"issn-type":[{"value":"0002-9149","type":"print"}],"subject":[],"published":{"date-parts":[[2026,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Left Atrial Appendage Occlusion Among Cancer Patients With Atrial Fibrillation: A Systematic Review and Updated Meta-Analysis","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.amjcard.2026.09.028","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}