{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,2]],"date-time":"2025-08-02T03:59:29Z","timestamp":1754107169442},"reference-count":51,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2004,9,1]],"date-time":"2004-09-01T00:00:00Z","timestamp":1093996800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The American Journal of Medicine Supplements"],"published-print":{"date-parts":[[2004,9]]},"DOI":"10.1016\/j.amjmed.2004.07.014","type":"journal-article","created":{"date-parts":[[2004,9,24]],"date-time":"2004-09-24T15:56:47Z","timestamp":1096041407000},"page":"23-29","source":"Crossref","is-referenced-by-count":7,"special_numbering":"S1","title":["Gastroesophageal reflux disease: Could intervention in childhood reduce the risk of later complications?"],"prefix":"10.1016","volume":"117","author":[{"given":"Benjamin D.","family":"Gold","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.amjmed.2004.07.014_BIB1","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1097\/00005176-200202000-00021","article-title":"Crohn's disease in an adolescent with galactosemia","volume":"34","author":"Marx","year":"2002","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"10.1016\/j.amjmed.2004.07.014_BIB2","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/S0016-5085(99)70549-4","article-title":"Clinical course and costs of care for Crohn's disease","volume":"117","author":"Silverstein","year":"1999","journal-title":"Gastroenterology"},{"key":"10.1016\/j.amjmed.2004.07.014_BIB3","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1016\/S0140-6736(02)08025-X","article-title":"Age at acquisition of Helicobacter pylori infection","volume":"359","author":"Malaty","year":"2002","journal-title":"Lancet"},{"key":"10.1016\/j.amjmed.2004.07.014_BIB4","doi-asserted-by":"crossref","first-page":"E1","DOI":"10.1542\/peds.108.1.e1","article-title":"Adult outcomes of pediatric recurrent abdominal pain","volume":"108","author":"Campo","year":"2001","journal-title":"Pediatrics"},{"key":"10.1016\/j.amjmed.2004.07.014_BIB5","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1136\/gut.35.5.590","article-title":"Omeprazole versus ranitidine for prevention of relapse in reflux oesophagitis","volume":"35","author":"Dent","year":"1994","journal-title":"Gut"},{"key":"10.1016\/j.amjmed.2004.07.014_BIB6","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1097\/00005176-200100002-00001","article-title":"Guidelines for evaluation and treatment of gastroesophageal reflux in infants and children","volume":"32","author":"Rudolph","year":"2001","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"10.1016\/j.amjmed.2004.07.014_BIB7","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1007\/s00464-001-8228-1","article-title":"Mechanisms responsible for recurrent gastroesophageal reflux in neurologically impaired children who underwent laparoscopic Nissen fundoplication","volume":"16","author":"Kawahara","year":"2002","journal-title":"Surg Endosc"},{"key":"10.1016\/j.amjmed.2004.07.014_BIB8","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1053\/gast.1997.v113.pm9247456","article-title":"Mechanisms responsible for gastroesophageal reflux in children","volume":"113","author":"Kawahara","year":"1997","journal-title":"Gastroenterology"},{"issue":"suppl 3A","key":"10.1016\/j.amjmed.2004.07.014_BIB9","doi-asserted-by":"crossref","first-page":"157S","DOI":"10.1016\/S0002-9343(03)00215-8","article-title":"Manometric evaluation of esophageal-protective reflexes in infants and children","volume":"115","author":"Jadcherla","year":"2003","journal-title":"Am J Med"},{"issue":"suppl 3A","key":"10.1016\/j.amjmed.2004.07.014_BIB10","doi-asserted-by":"crossref","first-page":"161S","DOI":"10.1016\/S0002-9343(03)00216-X","article-title":"Evaluation of gastroesophageal reflux events in children using multichannel intraluminal electrical impedance","volume":"115","author":"Wenzl","year":"2003","journal-title":"Am J Med"},{"key":"10.1016\/j.amjmed.2004.07.014_BIB11","doi-asserted-by":"crossref","first-page":"1818","DOI":"10.1023\/A:1025419717500","article-title":"Circadian variation of gastroesophageal reflux in children","volume":"48","author":"Steiner","year":"2003","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.amjmed.2004.07.014_BIB12","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1046\/j.1467-789X.2002.00049.x","article-title":"Gastro-oesophageal reflux disease in obesity","volume":"3","author":"Barak","year":"2002","journal-title":"Obes Rev"},{"key":"10.1016\/j.amjmed.2004.07.014_BIB13","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1381\/096089299765553007","article-title":"Treatment of morbid obesity and gastroesophageal reflux with hiatal hernia by Lap-Band","volume":"9","author":"Angrisani","year":"1999","journal-title":"Obes Surg"},{"key":"10.1016\/j.amjmed.2004.07.014_BIB14","doi-asserted-by":"crossref","first-page":"2290","DOI":"10.1023\/A:1026617106755","article-title":"Obesity correlates with gastroesophageal reflux","volume":"44","author":"Fisher","year":"1999","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.amjmed.2004.07.014_BIB15","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1001\/jama.290.1.66","article-title":"Obesity and estrogen as risk factors for gastroesophageal reflux symptoms","volume":"290","author":"Nilsson","year":"2003","journal-title":"JAMA"},{"key":"10.1016\/j.amjmed.2004.07.014_BIB16","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1080\/003655299750026326","article-title":"Weight loss has an independent beneficial effect on symptoms of gastro-oesophageal reflux in patients who are overweight","volume":"34","author":"Fraser-Moodie","year":"1999","journal-title":"Scand J Gastroenterol"},{"key":"10.1016\/j.amjmed.2004.07.014_BIB17","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1053\/gast.2002.30301","article-title":"Gastroesophageal reflux disease in monozygotic and dizygotic twins","volume":"122","author":"Cameron","year":"2002","journal-title":"Gastroenterology"},{"key":"10.1016\/j.amjmed.2004.07.014_BIB18","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1001\/jama.284.3.325","article-title":"Mapping of a gene for severe pediatric gastroesophageal reflux to chromosome 13q14","volume":"284","author":"Hu","year":"2000","journal-title":"JAMA"},{"key":"10.1016\/j.amjmed.2004.07.014_BIB19","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1136\/gut.52.8.1085","article-title":"Genetic influences in gastro-oesophageal reflux disease","volume":"52","author":"Mohammed","year":"2003","journal-title":"Gut"},{"key":"10.1016\/j.amjmed.2004.07.014_BIB20","doi-asserted-by":"crossref","first-page":"2725","DOI":"10.1111\/j.1572-0241.2002.07060.x","article-title":"Autosomal dominant infantile gastroesophageal reflux disease","volume":"97","author":"Orenstein","year":"2002","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.amjmed.2004.07.014_BIB21","doi-asserted-by":"crossref","unstructured":"Greenwald D. Aging, the gastrointestinal tract, and risk of age-related disease. Am J Med. 2004;117(suppl 5A):8S\u201313S","DOI":"10.1016\/j.amjmed.2004.07.019"},{"key":"10.1016\/j.amjmed.2004.07.014_BIB22","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1001\/archpedi.154.2.150","article-title":"Prevalence of symptoms of gastroesophageal reflux during childhood","volume":"154","author":"Nelson","year":"2000","journal-title":"Arch Pediatr Adolesc Med"},{"key":"10.1016\/j.amjmed.2004.07.014_BIB23","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1001\/archpedi.1997.02170430035007","article-title":"Prevalence of symptoms of gastroesophageal reflux during infancy","volume":"151","author":"Nelson","year":"1997","journal-title":"Arch Pediatr Adolesc Med"},{"key":"10.1016\/j.amjmed.2004.07.014_BIB24","first-page":"197","article-title":"The status of gastroesophageal reflux disease in hospitalized U.S. children: 1995\u20132000","volume":"33","author":"Gibbons","year":"2001","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"10.1016\/j.amjmed.2004.07.014_BIB25","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1097\/00005176-200209000-00018","article-title":"Childhood gastroesophageal reflux symptoms in adult patients","volume":"35","author":"Waring","year":"2002","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"10.1016\/j.amjmed.2004.07.014_BIB26","first-page":"1293","article-title":"Risk factors for Barrett's esophagus in community-based practice. GORGE consortium. Gastroenterology Outcomes Research Group in Endoscopy","volume":"92","author":"Lieberman","year":"1997","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.amjmed.2004.07.014_BIB27","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1056\/NEJM199903183401101","article-title":"Symptomatic gastroesophageal reflux as a risk factor for esophageal adenocarcinoma","volume":"340","author":"Lagergren","year":"1999","journal-title":"N Engl J Med"},{"key":"10.1016\/j.amjmed.2004.07.014_BIB28","doi-asserted-by":"crossref","unstructured":"Sharma P. Barrett esophagus: will effective treatment prevent the risk of progression to esophageal adenocarcinoma? Am J Med. 2004;117(suppl 5A):79S\u201385S","DOI":"10.1016\/j.amjmed.2004.07.013"},{"key":"10.1016\/j.amjmed.2004.07.014_BIB29","doi-asserted-by":"crossref","unstructured":"Chey WD. Endoscopy-negative reflux disease: concepts and clinical practice. Am J Med. 2004;117(suppl 5A):36S\u201343S","DOI":"10.1016\/j.amjmed.2004.07.016"},{"key":"10.1016\/j.amjmed.2004.07.014_BIB30","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/S1072-7515(02)01604-6","article-title":"Five-year comprehensive outcomes evaluation in 181 patients after laparoscopic Nissen fundoplication","volume":"196","author":"Anvari","year":"2003","journal-title":"J Am Coll Surg"},{"key":"10.1016\/j.amjmed.2004.07.014_BIB31","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/0165-5876(95)01130-4","article-title":"Sandifer syndrome","volume":"32","author":"Deskin","year":"1995","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"10.1016\/j.amjmed.2004.07.014_BIB32","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/S0387-7604(99)00025-X","article-title":"Gastrointestinal manifestations in children with cerebral palsy","volume":"21","author":"Del Giudice","year":"1999","journal-title":"Brain Dev"},{"key":"10.1016\/j.amjmed.2004.07.014_BIB33","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1080\/00365520212507","article-title":"The natural course of gastroesophageal reflux disease in children","volume":"37","author":"Ashorn","year":"2002","journal-title":"Scand J Gastroenterol"},{"key":"10.1016\/j.amjmed.2004.07.014_BIB34","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1177\/004947559202200324","article-title":"An unusual presentation of gastro-oesophageal reflux","volume":"22","author":"Dias","year":"1992","journal-title":"Trop Doct"},{"key":"10.1016\/j.amjmed.2004.07.014_BIB35","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1136\/jnnp.66.6.805","article-title":"Sandifer's syndrome and gastro-oesophageal reflux disease","volume":"66","author":"Theodoropoulos","year":"1999","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.amjmed.2004.07.014_BIB36","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1016\/0022-3468(90)90756-Y","article-title":"Complications of gastroesophageal antireflux surgery in neurologically impaired versus neurologically normal children","volume":"25","author":"Pearl","year":"1990","journal-title":"J Pediatr Surg"},{"key":"10.1016\/j.amjmed.2004.07.014_BIB37","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1053\/slas.2002.127000","article-title":"Gastroesophageal reflux disease in neurologically impaired children","volume":"9","author":"Wadie","year":"2002","journal-title":"Semin Laparosc Surg"},{"key":"10.1016\/j.amjmed.2004.07.014_BIB38","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1067\/mpd.2003.mpd0331","article-title":"Efficacy of telephone teaching of conservative therapy for infants with symptomatic gastroesophageal reflux referred by pediatricians to pediatric gastroenterologists","volume":"142","author":"Shalaby","year":"2003","journal-title":"J Pediatr"},{"key":"10.1016\/j.amjmed.2004.07.014_BIB39","doi-asserted-by":"crossref","unstructured":"Freston JW. Therapeutic choices in reflux disease: defining the criteria for selecting a proton pump inhibitor. Am J Med. 2004;117(suppl 5A):14S\u201322S","DOI":"10.1016\/j.amjmed.2004.07.020"},{"key":"10.1016\/j.amjmed.2004.07.014_BIB40","doi-asserted-by":"crossref","unstructured":"Tolia V, Johnston G, Stolle J, Lee C. Flavor and taste of lansoprazole strawberry-flavored delayed-release oral suspension preferred over ranitidine peppermint-flavored syrup in children aged 5 to 11 years. Paediatr Drugs. 2004;6:127\u2013131","DOI":"10.2165\/00148581-200406020-00006"},{"key":"10.1016\/j.amjmed.2004.07.014_BIB41","doi-asserted-by":"crossref","first-page":"25","DOI":"10.2165\/00128072-200305010-00003","article-title":"The use of proton pump inhibitors in children","volume":"5","author":"Gibbons","year":"2003","journal-title":"Paediatr Drugs"},{"key":"10.1016\/j.amjmed.2004.07.014_BIB42","doi-asserted-by":"crossref","first-page":"673","DOI":"10.2165\/00128072-200204100-00004","article-title":"Gastroesophageal reflux in children","volume":"4","author":"Gold","year":"2002","journal-title":"Paediatr Drugs"},{"key":"10.1016\/j.amjmed.2004.07.014_BIB43","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1067\/mpd.2000.109607","article-title":"Omeprazole for treatment of chronic erosive esophagitis in children","volume":"137","author":"Hassall","year":"2000","journal-title":"J Pediatr"},{"key":"10.1016\/j.amjmed.2004.07.014_BIB44","doi-asserted-by":"crossref","first-page":"S300","DOI":"10.1097\/00005176-200211004-00002","article-title":"Safety of lansoprazole in the treatment of gastroesophageal reflux disease in children","volume":"35","author":"Tolia","year":"2002","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"10.1016\/j.amjmed.2004.07.014_BIB45","first-page":"181","article-title":"pH, healing rate, and symptom relief in patients with GERD","volume":"72","author":"Huang","year":"1999","journal-title":"Yale J Biol Med"},{"key":"10.1016\/j.amjmed.2004.07.014_BIB46","doi-asserted-by":"crossref","first-page":"3101","DOI":"10.1111\/j.1572-0241.2000.03256.x","article-title":"Pharmacokinetics of orally administered omeprazole in children","volume":"95","author":"Andersson","year":"2000","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.amjmed.2004.07.014_BIB47","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/S1055-8586(02)00021-5","article-title":"The failed fundoplication","volume":"12","author":"Langer","year":"2003","journal-title":"Semin Pediatr Surg"},{"key":"10.1016\/j.amjmed.2004.07.014_BIB48","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1097\/00000658-199709000-00011","article-title":"Reoperation after Nissen fundoplication in children with gastroesophageal reflux","volume":"226","author":"Dalla Vecchia","year":"1997","journal-title":"Ann Surg"},{"key":"10.1016\/j.amjmed.2004.07.014_BIB49","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1097\/00005176-200307000-00022","article-title":"Fundoplication","volume":"37","author":"Esposito","year":"2003","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"10.1016\/j.amjmed.2004.07.014_BIB50","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1542\/peds.101.3.419","article-title":"Surgical treatment of gastroesophageal reflux in children","volume":"101","author":"Fonkalsrud","year":"1998","journal-title":"Pediatrics"},{"key":"10.1016\/j.amjmed.2004.07.014_BIB51","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/S1055-8586(98)70023-X","article-title":"Nissen fundoplication for gastroesophageal reflux disease in infants and children","volume":"7","author":"Fonkalsrud","year":"1998","journal-title":"Semin Pediatr Surg"}],"container-title":["The American Journal of Medicine Supplements"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1548276604000159?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1548276604000159?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,4,3]],"date-time":"2020-04-03T05:51:07Z","timestamp":1585893067000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1548276604000159"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,9]]},"references-count":51,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2004,9]]}},"alternative-id":["S1548276604000159"],"URL":"https:\/\/doi.org\/10.1016\/j.amjmed.2004.07.014","relation":{},"ISSN":["1548-2766"],"issn-type":[{"value":"1548-2766","type":"print"}],"subject":[],"published":{"date-parts":[[2004,9]]}}}