{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T03:03:13Z","timestamp":1789614193514,"version":"build-2803163510"},"reference-count":27,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2012,7,1]],"date-time":"2012-07-01T00:00:00Z","timestamp":1341100800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,7,1]],"date-time":"2012-07-01T00:00:00Z","timestamp":1341100800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 NS057127"],"award-info":[{"award-number":["R01 NS057127"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["U01 NS054630"],"award-info":[{"award-number":["U01 NS054630"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 NS062778"],"award-info":[{"award-number":["R01 NS062778"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["U01 NS059041"],"award-info":[{"award-number":["U01 NS059041"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000968","name":"American Heart Association","doi-asserted-by":"publisher","award":["0840053N"],"award-info":[{"award-number":["0840053N"]}],"id":[{"id":"10.13039\/100000968","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["amjmed.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Medicine"],"published-print":{"date-parts":[[2012,7]]},"DOI":"10.1016\/j.amjmed.2011.09.031","type":"journal-article","created":{"date-parts":[[2012,5,3]],"date-time":"2012-05-03T20:48:17Z","timestamp":1336078097000},"page":"718.e1-718.e6","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":28,"title":["Systolic Blood Pressure Reduction and Risk of Acute Renal Injury in Patients with Intracerebral Hemorrhage"],"prefix":"10.1016","volume":"125","author":[{"given":"Adnan I.","family":"Qureshi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuko Y.","family":"Palesch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renee","family":"Martin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jill","family":"Novitzke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salvador","family":"Cruz Flores","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asad","family":"Ehtisham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua N.","family":"Goldstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jawad F.","family":"Kirmani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haitham M.","family":"Hussein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. Fareed K.","family":"Suri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nauman","family":"Tariq","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.amjmed.2011.09.031_bib1","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.jstrokecerebrovasdis.2009.11.012","article-title":"Renal dysfunction and discharge destination in patients with intracerebral hemorrhage","volume":"20","author":"Ovbiagele","year":"2011","journal-title":"J Stroke Cerebrovasc Dis"},{"key":"10.1016\/j.amjmed.2011.09.031_bib2","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1007\/BF03021626","article-title":"Case report: profound hypotension associated with labetalol therapy in a patient with cerebral aneurysms and subarachnoid hemorrhage","volume":"53","author":"Jivraj","year":"2006","journal-title":"Can J Anaesth"},{"key":"10.1016\/j.amjmed.2011.09.031_bib3","doi-asserted-by":"crossref","first-page":"412","DOI":"10.5694\/j.1326-5377.1987.tb120332.x","article-title":"Focal cerebral ischaemia and infarction due to antihypertensive therapy","volume":"146","author":"Hankey","year":"1987","journal-title":"Med J Aust"},{"key":"10.1016\/j.amjmed.2011.09.031_bib4","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1007\/s12028-008-9169-5","article-title":"The hydration influence on the risk of stroke (THIRST) study","volume":"10","author":"Rodriguez","year":"2009","journal-title":"Neurocrit Care"},{"key":"10.1016\/j.amjmed.2011.09.031_bib5","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1161\/CIRCULATIONAHA.107.723874","article-title":"Acute hypertensive response in patients with stroke: pathophysiology and management","volume":"118","author":"Qureshi","year":"2008","journal-title":"Circulation"},{"key":"10.1016\/j.amjmed.2011.09.031_bib6","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1159\/000285165","article-title":"Association between renal function and clinical outcome in patients with acute stroke","volume":"63","author":"Hao","year":"2010","journal-title":"Eur Neurol"},{"key":"10.1016\/j.amjmed.2011.09.031_bib7","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1093\/ndt\/gfn471","article-title":"Renal dysfunction in acute stroke: an independent predictor of long-term all combined vascular events and overall mortality","volume":"24","author":"Tsagalis","year":"2009","journal-title":"Nephrol Dial Transplant"},{"key":"10.1016\/j.amjmed.2011.09.031_bib8","doi-asserted-by":"crossref","first-page":"2393","DOI":"10.1161\/STROKEAHA.108.546127","article-title":"CT angiography for intracerebral hemorrhage does not increase risk of acute nephropathy","volume":"40","author":"Oleinik","year":"2009","journal-title":"Stroke"},{"key":"10.1016\/j.amjmed.2011.09.031_bib9","doi-asserted-by":"crossref","first-page":"537","DOI":"10.3171\/jns.1993.78.4.0537","article-title":"A randomized controlled trial of high-dose intravenous nicardipine in aneurysmal subarachnoid hemorrhage","volume":"78","author":"Haley","year":"1993","journal-title":"J Neurosurg"},{"key":"10.1016\/j.amjmed.2011.09.031_bib10","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1385\/NCC:6:1:56","article-title":"Antihypertensive Treatment of Acute Cerebral Hemorrhage (ATACH): rationale and design","volume":"6","author":"Qureshi","year":"2007","journal-title":"Neurocrit Care"},{"key":"10.1016\/j.amjmed.2011.09.031_bib11","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1097\/CCM.0b013e3181b9e1a5","article-title":"Antihypertensive treatment of acute cerebral hemorrhage","volume":"38","year":"2010","journal-title":"Crit Care Med"},{"key":"10.1016\/j.amjmed.2011.09.031_bib12","doi-asserted-by":"crossref","first-page":"R110","DOI":"10.1186\/cc6997","article-title":"Acute kidney injury in intensive care unit patients: a comparison between the RIFLE and the Acute Kidney Injury Network classifications","volume":"12","author":"Lopes","year":"2008","journal-title":"Crit Care"},{"key":"10.1016\/j.amjmed.2011.09.031_bib13","doi-asserted-by":"crossref","first-page":"2259","DOI":"10.1161\/01.CIR.0000016043.87291.33","article-title":"Incidence and prognostic importance of acute renal failure after percutaneous coronary intervention","volume":"105","author":"Rihal","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.amjmed.2011.09.031_bib14","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1056\/NEJM200007203430304","article-title":"Prevention of radiographic-contrast-agent-induced reductions in renal function by acetylcysteine","volume":"343","author":"Tepel","year":"2000","journal-title":"N Engl J Med"},{"key":"10.1016\/j.amjmed.2011.09.031_bib15","doi-asserted-by":"crossref","first-page":"1542","DOI":"10.1016\/S0735-1097(00)00917-7","article-title":"The prognostic implications of further renal function deterioration within 48 h of interventional coronary procedures in patients with pre-existent chronic renal insufficiency","volume":"36","author":"Gruberg","year":"2000","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.amjmed.2011.09.031_bib16","doi-asserted-by":"crossref","first-page":"R31","DOI":"10.1186\/cc5713","article-title":"Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury","volume":"11","author":"Mehta","year":"2007","journal-title":"Crit Care"},{"key":"10.1016\/j.amjmed.2011.09.031_bib17","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1097\/01.mnh.0000165894.90748.72","article-title":"Are small changes in serum creatinine an important risk factor?","volume":"14","author":"Praught","year":"2005","journal-title":"Curr Opin Nephrol Hypertens"},{"key":"10.1016\/j.amjmed.2011.09.031_bib18","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1097\/CCM.0b013e318169181a","article-title":"Impact of minimal increases in serum creatinine on outcome in patients after cardiothoracic surgery: do we have to revise current definitions of acute renal failure?","volume":"36","author":"Lassnigg","year":"2008","journal-title":"Crit Care Med"},{"key":"10.1016\/j.amjmed.2011.09.031_bib19","doi-asserted-by":"crossref","first-page":"1975","DOI":"10.1097\/01.CCM.0000220763.85974.E8","article-title":"Treatment of acute hypertension in patients with intracerebral hemorrhage using American Heart Association guidelines","volume":"34","author":"Qureshi","year":"2006","journal-title":"Crit Care Med"},{"key":"10.1016\/j.amjmed.2011.09.031_bib20","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1097\/00003246-199506000-00004","article-title":"Medical complications of aneurysmal subarachnoid hemorrhage: a report of the multicenter, cooperative aneurysm study","volume":"23","author":"Solenski","year":"1995","journal-title":"Crit Care Med"},{"key":"10.1016\/j.amjmed.2011.09.031_bib21","doi-asserted-by":"crossref","first-page":"2662","DOI":"10.1001\/archinte.1989.00390120034008","article-title":"Intravenous nicardipine for the treatment of severe hypertension","volume":"149","author":"Wallin","year":"1989","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.amjmed.2011.09.031_bib22","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1213\/ane.0b013e31818240db","article-title":"The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients","volume":"107","author":"Aronson","year":"2008","journal-title":"Anesth Analg"},{"key":"10.1016\/j.amjmed.2011.09.031_bib23","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1586\/erc.09.1","article-title":"Clevidipine in the treatment of perioperative hypertension: assessing safety events in the ECLIPSE trials","volume":"7","author":"Aronson","year":"2009","journal-title":"Expert Rev Cardiovasc Ther"},{"key":"10.1016\/j.amjmed.2011.09.031_bib24","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1291\/hypres.19.31","article-title":"Disparate effects of calcium antagonists on renal microcirculation","volume":"19","author":"Hayashi","year":"1996","journal-title":"Hypertens Res"},{"key":"10.1016\/j.amjmed.2011.09.031_bib25","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.2337\/diab.35.11.1206","article-title":"Renal effects of nicardipine, a calcium entry blocker, in hypertensive type II diabetic patients with nephropathy","volume":"35","author":"Baba","year":"1986","journal-title":"Diabetes"},{"key":"10.1016\/j.amjmed.2011.09.031_bib26","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1016\/0002-8703(86)90063-3","article-title":"Renal effects of nicardipine in patients with mild-to-moderate essential hypertension","volume":"111","author":"Baba","year":"1986","journal-title":"Am Heart J"},{"key":"10.1016\/j.amjmed.2011.09.031_bib27","doi-asserted-by":"crossref","first-page":"R139","DOI":"10.1186\/cc7114","article-title":"A systematic review on quality indicators for tight glycaemic control in critically ill patients: need for an unambiguous indicator reference subset","volume":"12","author":"Eslami","year":"2008","journal-title":"Crit Care"}],"container-title":["The American Journal of Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002934312000344?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002934312000344?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T10:27:28Z","timestamp":1762079248000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002934312000344"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,7]]},"references-count":27,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2012,7]]}},"alternative-id":["S0002934312000344"],"URL":"https:\/\/doi.org\/10.1016\/j.amjmed.2011.09.031","relation":{},"ISSN":["0002-9343"],"issn-type":[{"value":"0002-9343","type":"print"}],"subject":[],"published":{"date-parts":[[2012,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Systolic Blood Pressure Reduction and Risk of Acute Renal Injury in Patients with Intracerebral Hemorrhage","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.amjmed.2011.09.031","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}