{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T23:45:20Z","timestamp":1782776720753,"version":"3.54.5"},"reference-count":42,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2019,12,1]],"date-time":"2019-12-01T00:00:00Z","timestamp":1575158400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,12,1]],"date-time":"2019-12-01T00:00:00Z","timestamp":1575158400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001711","name":"Swiss National Science Foundation","doi-asserted-by":"publisher","award":["33CSCO-122659\/139470"],"award-info":[{"award-number":["33CSCO-122659\/139470"]}],"id":[{"id":"10.13039\/501100001711","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["amjmed.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Medicine"],"published-print":{"date-parts":[[2019,12]]},"DOI":"10.1016\/j.amjmed.2019.05.041","type":"journal-article","created":{"date-parts":[[2019,6,24]],"date-time":"2019-06-24T10:59:41Z","timestamp":1561373981000},"page":"e835-e843","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"title":["Prognostic Value of Electrocardiography in Elderly Patients with Acute Pulmonary Embolism"],"prefix":"10.1016","volume":"132","author":[{"given":"Lucy","family":"Bolt","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandro","family":"Lauber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Limacher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daryoush","family":"Samim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Axel","family":"L\u00f6we","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobias","family":"Tritschler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Baumgartner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Drahomir","family":"Aujesky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"43","key":"10.1016\/j.amjmed.2019.05.041_bb0005","doi-asserted-by":"crossref","first-page":"3033","DOI":"10.1093\/eurheartj\/ehu283","article-title":"2014 ESC guidelines on the diagnosis and management of acute pulmonary embolism","volume":"35","author":"Konstantinides","year":"2014","journal-title":"Eur Heart J"},{"key":"10.1016\/j.amjmed.2019.05.041_bb0010","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.thromres.2018.01.025","article-title":"Prognostic significance of electrocardiogram at presentation in patients with pulmonary embolism of different severity","volume":"163","author":"Casazza","year":"2018","journal-title":"Thromb Res"},{"issue":"3","key":"10.1016\/j.amjmed.2019.05.041_bb0015","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.amjmed.2008.08.031","article-title":"Prognostic value of ECG among patients with acute pulmonary embolism and normal blood pressure","volume":"122","author":"Vanni","year":"2009","journal-title":"Am J Med"},{"issue":"7","key":"10.1016\/j.amjmed.2019.05.041_bb0020","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1016\/j.amjcard.2007.06.015","article-title":"Electrocardiographic score and short-term outcomes of acute pulmonary embolism","volume":"100","author":"Toosi","year":"2007","journal-title":"Am J Cardiol"},{"issue":"3","key":"10.1016\/j.amjmed.2019.05.041_bb0025","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1016\/j.amjcard.2005.03.099","article-title":"Role of electrocardiography in identifying right ventricular dysfunction in acute pulmonary embolism","volume":"96","author":"Punukollu","year":"2005","journal-title":"Am J Cardiol"},{"issue":"1019","key":"10.1016\/j.amjmed.2019.05.041_bb0030","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1259\/bjr\/22397455","article-title":"Thrombus load and acute right ventricular failure in pulmonary embolism: correlation and demonstration of a \"tipping point\" on CT pulmonary angiography","volume":"85","author":"Wong","year":"2012","journal-title":"Br J Radiol"},{"issue":"9162","key":"10.1016\/j.amjmed.2019.05.041_bb0035","doi-asserted-by":"crossref","first-page":"1386","DOI":"10.1016\/S0140-6736(98)07534-5","article-title":"Acute pulmonary embolism: clinical outcomes in the International Cooperative Pulmonary Embolism Registry (ICOPER)","volume":"353","author":"Goldhaber","year":"1999","journal-title":"Lancet"},{"issue":"4","key":"10.1016\/j.amjmed.2019.05.041_bb0040","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1136\/hrt.77.4.346","article-title":"Prognostic significance of right ventricular afterload stress detected by echocardiography in patients with clinically suspected pulmonary embolism","volume":"77","author":"Kasper","year":"1997","journal-title":"Heart"},{"issue":"7","key":"10.1016\/j.amjmed.2019.05.041_bb0045","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1007\/s00380-019-01340-1","article-title":"Prognostic value of echocardiographic parameters for right ventricular function in patients with acute non-massive pulmonary embolism","volume":"34","author":"Lee","year":"2019","journal-title":"Heart Vessel"},{"issue":"3","key":"10.1016\/j.amjmed.2019.05.041_bb0050","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1157\/13116651","article-title":"Prognostic value of electrocardiographic findings in hemodynamically stable patients with acute symptomatic pulmonary embolism","volume":"61","author":"Escobar","year":"2008","journal-title":"Rev Esp Cardiol"},{"issue":"5","key":"10.1016\/j.amjmed.2019.05.041_bb0055","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1183\/09031936.05.00119704","article-title":"Prognostic value of the ECG on admission in patients with acute major pulmonary embolism","volume":"25","author":"Geibel","year":"2005","journal-title":"Eur Respir J"},{"issue":"12","key":"10.1016\/j.amjmed.2019.05.041_bb0060","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1016\/S0195-668X(03)00132-5","article-title":"QR in V1--an ECG sign associated with right ventricular strain and adverse clinical outcome in pulmonary embolism","volume":"24","author":"Kucher","year":"2003","journal-title":"Eur Heart J"},{"issue":"6","key":"10.1016\/j.amjmed.2019.05.041_bb0065","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1253\/circj.70.750","article-title":"Prognostic significance of inverted T waves in patients with acute pulmonary embolism","volume":"70","author":"Kosuge","year":"2006","journal-title":"Circ J"},{"issue":"6","key":"10.1016\/j.amjmed.2019.05.041_bb0070","doi-asserted-by":"crossref","first-page":"648","DOI":"10.5603\/CJ.2011.0028","article-title":"Electrocardiography and prognosis of patients with acute pulmonary embolism","volume":"18","author":"Kukla","year":"2011","journal-title":"Cardiol J"},{"issue":"8","key":"10.1016\/j.amjmed.2019.05.041_bb0075","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1001\/archinte.1994.00420080053005","article-title":"The epidemiology of diagnosed pulmonary embolism and deep venous thrombosis in the elderly","volume":"154","author":"Kniffin","year":"1994","journal-title":"Arch Intern Med"},{"issue":"4","key":"10.1016\/j.amjmed.2019.05.041_bb0080","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1111\/j.1538-7836.2007.02450.x","article-title":"Incidence and mortality of venous thrombosis: a population-based study","volume":"5","author":"Naess","year":"2007","journal-title":"J Thromb Haemost"},{"issue":"5","key":"10.1016\/j.amjmed.2019.05.041_bb0085","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1055\/s-0037-1613887","article-title":"Incidence of venous thromboembolism: a community-based study in Western France. EPI-GETBP Study Group. Groupe d'Etude de la Thrombose de Bretagne Occidentale","volume":"83","author":"Oger","year":"2000","journal-title":"Thromb Haemost"},{"key":"10.1016\/j.amjmed.2019.05.041_bb0090","doi-asserted-by":"crossref","first-page":"g5992","DOI":"10.1136\/bmj.g5992","article-title":"Sex differences in lifetime risk and first manifestation of cardiovascular disease: prospective population based cohort study","volume":"349","author":"Leening","year":"2014","journal-title":"BMJ"},{"key":"10.1016\/j.amjmed.2019.05.041_bb0095","first-page":"1","article-title":"Hypertension prevalence and control among adults: United States, 2015-2016","volume":"289","author":"Fryar","year":"2017","journal-title":"NCHS Data Brief"},{"issue":"3","key":"10.1016\/j.amjmed.2019.05.041_bb0100","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1164\/rccm.201410-1876PP","article-title":"Blue journal conference. Aging and susceptibility to lung disease","volume":"191","author":"Thannickal","year":"2015","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.amjmed.2019.05.041_bb0105","doi-asserted-by":"crossref","first-page":"3","DOI":"10.7603\/s40602-016-0003-6","article-title":"2014 PHA cinical practice guidelines for the diagnosis and management of patients with coronary heart disease","volume":"24","author":"Lazaro","year":"2016","journal-title":"ASEAN Heart J"},{"issue":"5","key":"10.1016\/j.amjmed.2019.05.041_bb0110","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1161\/01.CIR.42.5.903","article-title":"A dynamic electrocardiographic concept useful in the diagnosis of cor pulmonale. Result of a survey of 200 patients with chronic obstructice pulmonary disease","volume":"42","author":"Kilcoyne","year":"1970","journal-title":"Circulation"},{"key":"10.1016\/j.amjmed.2019.05.041_bb0115","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1161\/01.CIR.31.6.888","article-title":"Electrocardiographic findings among the adult population of a total natural community, Tecumseh, Michigan","volume":"31","author":"Ostrander","year":"1965","journal-title":"Circulation"},{"issue":"1","key":"10.1016\/j.amjmed.2019.05.041_bb0120","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1111\/j.1542-474X.2010.00404.x","article-title":"Electrocardiographic abnormalities in patients with severe versus mild or moderate chronic obstructive pulmonary disease followed in an academic outpatient pulmonary clinic","volume":"16","author":"Holtzman","year":"2011","journal-title":"Ann Noninvasive Electrocardiol"},{"issue":"4","key":"10.1016\/j.amjmed.2019.05.041_bb0125","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1007\/s11239-013-0875-2","article-title":"The Swiss cohort of elderly patients with venous thromboembolism (SWITCO65+): rationale and methodology","volume":"36","author":"Mean","year":"2013","journal-title":"J Thromb Thrombolysis"},{"issue":"16","key":"10.1016\/j.amjmed.2019.05.041_bb0130","doi-asserted-by":"crossref","first-page":"1788","DOI":"10.1161\/CIR.0b013e318214914f","article-title":"Management of massive and submassive pulmonary embolism, iliofemoral deep vein thrombosis, and chronic thromboembolic pulmonary hypertension","volume":"123","author":"Jaff","year":"2011","journal-title":"Circulation"},{"issue":"5","key":"10.1016\/j.amjmed.2019.05.041_bb0135","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0155973","article-title":"Comparison of cardiac and non-cardiac biomarkers for risk stratification in elderly patients with non-massive pulmonary embolism","volume":"11","author":"Vuilleumier","year":"2016","journal-title":"PLoS One"},{"issue":"12","key":"10.1016\/j.amjmed.2019.05.041_bb0140","doi-asserted-by":"crossref","first-page":"1958","DOI":"10.1016\/j.amjcard.2013.08.030","article-title":"Relation of electrocardiographic changes in pulmonary embolism to right ventricular enlargement","volume":"112","author":"Stein","year":"2013","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.amjmed.2019.05.041_bb0145","doi-asserted-by":"crossref","DOI":"10.1111\/anec.12439","article-title":"Correlations between electrocardiogram and biomarkers in acute pulmonary embolism: Analysis of ZATPOL-2 Registry","volume":"22","author":"Kukla","year":"2017","journal-title":"Ann Noninvasive Electrocardiol"},{"issue":"1","key":"10.1016\/j.amjmed.2019.05.041_bb0150","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.amjcard.2018.03.013","article-title":"Multimodality assessment of right ventricular strain in patients with acute pulmonary embolism","volume":"122","author":"Carroll","year":"2018","journal-title":"Am J Cardiol"},{"issue":"6","key":"10.1016\/j.amjmed.2019.05.041_bb0155","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/j.ajem.2014.01.043","article-title":"Electrocardiographic abnormalities in patients with acute pulmonary embolism complicated by cardiogenic shock","volume":"32","author":"Kukla","year":"2014","journal-title":"Am J Emerg Med"},{"key":"10.1016\/j.amjmed.2019.05.041_bb0160","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1177\/001316446002000104","article-title":"A coefficient of agreement for nominal scales","volume":"20","author":"Cohen","year":"1960","journal-title":"Educ Psychol Meas"},{"issue":"1","key":"10.1016\/j.amjmed.2019.05.041_bb0165","doi-asserted-by":"crossref","first-page":"159","DOI":"10.2307\/2529310","article-title":"The measurement of observer agreement for categorical data","volume":"33","author":"Landis","year":"1977","journal-title":"Biometrics"},{"key":"10.1016\/j.amjmed.2019.05.041_bb0170","series-title":"Multiple Imputation for Nonresponse in Surveys","author":"Rubin","year":"1987"},{"issue":"5","key":"10.1016\/j.amjmed.2019.05.041_bb0175","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1002\/jhm.868","article-title":"Electrocardiogram score predicts severity of pulmonary embolism in hemodynamically stable patients","volume":"6","author":"Golpe","year":"2011","journal-title":"J Hosp Med"},{"issue":"10","key":"10.1016\/j.amjmed.2019.05.041_bb0200","doi-asserted-by":"crossref","first-page":"499","DOI":"10.4070\/kcj.2010.40.10.499","article-title":"Electrocardiography patterns and the role of the electrocardiography score for risk stratification in acute pulmonary embolism","volume":"40","author":"Ryu","year":"2010","journal-title":"Korean Circ J"},{"issue":"2","key":"10.1016\/j.amjmed.2019.05.041_bb0180","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1378\/chest.07-1231","article-title":"Prognostic value of echocardiographic right\/left ventricular end-diastolic diameter ratio in patients with acute pulmonary embolism: results from a monocenter registry of 1,416 patients","volume":"133","author":"Fr\u00e9mont","year":"2008","journal-title":"Chest"},{"key":"10.1016\/j.amjmed.2019.05.041_bb0185","doi-asserted-by":"crossref","first-page":"e403","DOI":"10.1016\/j.crvasa.2015.12.001","article-title":"Elevated systolic pulmonary artery pressure for prediction of myocardial necrosis and right ventricular dysfunction in acute pulmonary embolism","volume":"58","author":"Keller","year":"2016","journal-title":"Cor Vasa"},{"issue":"3","key":"10.1016\/j.amjmed.2019.05.041_bb0190","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1253\/circj.67.229","article-title":"Relationship between ECG findings and pulmonary artery pressure in patients with acute massive pulmonary thromboembolism","volume":"67","author":"Yoshinaga","year":"2003","journal-title":"Circ J."},{"issue":"2","key":"10.1016\/j.amjmed.2019.05.041_bb0195","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1378\/chest.120.2.474","article-title":"Assessment of cardiac stress from massive pulmonary embolism with 12-lead ECG","volume":"120","author":"Daniel","year":"2001","journal-title":"Chest"},{"issue":"5","key":"10.1016\/j.amjmed.2019.05.041_bb0205","doi-asserted-by":"crossref","first-page":"1651","DOI":"10.1378\/chest.125.5.1651","article-title":"ECG score predicts those with the greatest percentage of perfusion defects due to acute pulmonary thromboembolic disease","volume":"125","author":"Iles","year":"2004","journal-title":"Chest"},{"issue":"15","key":"10.1016\/j.amjmed.2019.05.041_bb0210","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1056\/NEJMoa021274","article-title":"Management Strategies and Prognosis of Pulmonary Embolism-3 Trial Investigators. Heparin plus alteplase compared with heparin alone in patients with submassive pulmonary embolism","volume":"347","author":"Konstantinides","year":"2002","journal-title":"N Engl J Med"}],"container-title":["The American Journal of Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002934319305236?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002934319305236?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T09:18:10Z","timestamp":1757582290000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002934319305236"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12]]},"references-count":42,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2019,12]]}},"alternative-id":["S0002934319305236"],"URL":"https:\/\/doi.org\/10.1016\/j.amjmed.2019.05.041","relation":{},"ISSN":["0002-9343"],"issn-type":[{"value":"0002-9343","type":"print"}],"subject":[],"published":{"date-parts":[[2019,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Prognostic Value of Electrocardiography in Elderly Patients with Acute Pulmonary Embolism","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.amjmed.2019.05.041","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}