{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T20:21:01Z","timestamp":1793391661653,"version":"4.5.0"},"reference-count":26,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["amjmed.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Medicine"],"published-print":{"date-parts":[[2020,4]]},"DOI":"10.1016\/j.amjmed.2019.10.015","type":"journal-article","created":{"date-parts":[[2019,11,8]],"date-time":"2019-11-08T23:04:45Z","timestamp":1573254285000},"page":"492-499","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":83,"title":["Epidemiology Characteristics and Outcome of Patients With Clinically Diagnosed Acute Myocarditis"],"prefix":"10.1016","volume":"133","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6486-8170","authenticated-orcid":false,"given":"Anan","family":"Younis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shlomi","family":"Matetzky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7771-6096","authenticated-orcid":false,"given":"Wesam","family":"Mulla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eyas","family":"Masalha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoav","family":"Afel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando","family":"Chernomordik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex","family":"Fardman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Orly","family":"Goitein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sagit","family":"Ben-Zekry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yael","family":"Peled","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Avishay","family":"Grupper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roy","family":"Beigel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.amjmed.2019.10.015_bib0001","doi-asserted-by":"crossref","first-page":"1526","DOI":"10.1056\/NEJMra0800028","article-title":"Myocarditis","volume":"360","author":"Cooper","year":"2009","journal-title":"N Engl J Med"},{"key":"10.1016\/j.amjmed.2019.10.015_bib0002","doi-asserted-by":"crossref","first-page":"2636","DOI":"10.1093\/eurheartj\/eht210","article-title":"Current state of knowledge on aetiology, diagnosis, management, and therapy of myocarditis: a position statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases","volume":"34","author":"Caforio","year":"2013","journal-title":"Eur Heart J"},{"key":"10.1016\/j.amjmed.2019.10.015_bib0003","doi-asserted-by":"crossref","first-page":"2363","DOI":"10.1016\/j.jacc.2017.09.023","article-title":"Eosinophilic myocarditis: characteristics, treatment, and outcomes","volume":"70","author":"Brambatti","year":"2017","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.amjmed.2019.10.015_bib0004","doi-asserted-by":"crossref","first-page":"1749","DOI":"10.1056\/NEJMoa1609214","article-title":"Fulminant myocarditis with combination immune checkpoint blockade","volume":"375","author":"Johnson","year":"2016","journal-title":"N Engl J Med"},{"key":"10.1016\/j.amjmed.2019.10.015_bib0005","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1056\/NEJMra1703481","article-title":"Immune-related adverse events associated with immune checkpoint blockade","volume":"378","author":"Postow","year":"2018","journal-title":"N Engl J Med"},{"key":"10.1016\/j.amjmed.2019.10.015_bib0006","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1161\/CIRCEP.113.001376","article-title":"Pathogeneses of sudden cardiac death in national collegiate athletic association athletes","volume":"7","author":"Harmon","year":"2014","journal-title":"Circ Arrhythm Electrophysiol."},{"key":"10.1016\/j.amjmed.2019.10.015_bib0007","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.1016\/j.amjmed.2016.02.031","article-title":"Demographics and epidemiology of sudden deaths in young competitive athletes: from the United States National Registry","volume":"129","author":"Maron","year":"2016","journal-title":"Am J Med"},{"key":"10.1016\/j.amjmed.2019.10.015_bib0008","doi-asserted-by":"crossref","first-page":"1326","DOI":"10.1093\/eurheartj\/ehm076","article-title":"A prospective study of biopsy-proven myocarditis: prognostic relevance of clinical and aetiopathogenetic features at diagnosis","volume":"28","author":"Caforio","year":"2007","journal-title":"Eur Heart J"},{"key":"10.1016\/j.amjmed.2019.10.015_bib0009","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1161\/CIRCULATIONAHA.108.769489","article-title":"Predictors of outcome in patients with suspected myocarditis","volume":"118","author":"Kindermann","year":"2008","journal-title":"Circulation"},{"key":"10.1016\/j.amjmed.2019.10.015_bib0010","doi-asserted-by":"crossref","first-page":"1604","DOI":"10.1016\/j.jacc.2012.01.007","article-title":"Long-term follow-up of biopsy-proven viral myocarditis: predictors of mortality and incomplete recovery","volume":"59","author":"Grun","year":"2012","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.amjmed.2019.10.015_bib0011","doi-asserted-by":"crossref","first-page":"2384","DOI":"10.1161\/CIRCULATIONAHA.113.003092","article-title":"Long-term evolution and prognostic stratification of biopsy-proven active myocarditis","volume":"128","author":"Anzini","year":"2013","journal-title":"Circulation"},{"key":"10.1016\/j.amjmed.2019.10.015_bib0012","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1161\/CIRCULATIONAHA.117.026386","article-title":"Survival and left ventricular function changes in fulminant versus nonfulminant acute myocarditis","volume":"136","author":"Ammirati","year":"2017","journal-title":"Circulation"},{"key":"10.1016\/j.amjmed.2019.10.015_bib0013","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/j.jacc.2019.04.063","article-title":"Fulminant versus acute nonfulminant myocarditis in patients with left ventricular systolic dysfunction","volume":"74","author":"Ammirati","year":"2019","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.amjmed.2019.10.015_bib0014","doi-asserted-by":"crossref","first-page":"1581","DOI":"10.1016\/j.jacc.2012.08.001","article-title":"Third universal definition of myocardial infarction","volume":"60","author":"Thygesen","year":"2012","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.amjmed.2019.10.015_bib0015","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1016\/j.ehj.2003.10.031","article-title":"Diagnostic value of abnormal Q waves for identification of preclinical carriers of hypertrophic cardiomyopathy based on a molecular genetic diagnosis","volume":"25","author":"Konno","year":"2004","journal-title":"Eur Heart J"},{"key":"10.1016\/j.amjmed.2019.10.015_bib0016","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/j.jelectrocard.2016.04.002","article-title":"Relationship between T-wave inversion and transmural myocardial edema as evidenced by cardiac magnetic resonance in patients with clinically suspected acute myocarditis: clinical and prognostic implications","volume":"49","author":"De Lazzari","year":"2016","journal-title":"J Electrocardiol"},{"key":"10.1016\/j.amjmed.2019.10.015_bib0017","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1016\/j.jacc.2009.02.007","article-title":"Cardiovascular magnetic resonance in myocarditis: A JACC White Paper","volume":"53","author":"Friedrich","year":"2009","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.amjmed.2019.10.015_bib0018","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1148\/radiology.199.1.8633172","article-title":"\"Black blood\" T2-weighted inversion-recovery MR imaging of the heart","volume":"199","author":"Simonetti","year":"1996","journal-title":"Radiology"},{"key":"10.1016\/j.amjmed.2019.10.015_bib0019","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.116.005306","article-title":"Occurrence and features of childhood myocarditis: a nationwide study in Finland","volume":"6","author":"Arola","year":"2017","journal-title":"J Am Heart Assoc"},{"key":"10.1016\/j.amjmed.2019.10.015_bib0020","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1186\/s12968-015-0185-2","article-title":"Cardiovascular magnetic resonance predictors of clinical outcome in patients with suspected acute myocarditis","volume":"17","author":"Sanguineti","year":"2015","journal-title":"J Cardiovasc Magn Reson"},{"key":"10.1016\/j.amjmed.2019.10.015_bib0021","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCULATIONAHA.118.035319","article-title":"Clinical presentation and outcome in a contemporary cohort of patients with acute myocarditis: The Multicenter Lombardy Registry","author":"Ammirati","year":"2018","journal-title":"Circulation"},{"key":"10.1016\/j.amjmed.2019.10.015_bib0022","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1056\/NEJM200003093421003","article-title":"Long-term outcome of fulminant myocarditis as compared with acute (nonfulminant) myocarditis","volume":"342","author":"McCarthy","year":"2000","journal-title":"N Engl J Med"},{"key":"10.1016\/j.amjmed.2019.10.015_bib0023","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/j.ahj.2005.03.037","article-title":"Survival in biopsy-proven myocarditis: a long-term retrospective analysis of the histopathologic, clinical, and hemodynamic predictors","volume":"151","author":"Magnani","year":"2006","journal-title":"Am Heart J"},{"key":"10.1016\/j.amjmed.2019.10.015_bib0024","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1253\/circj.68.734","article-title":"Risk factors for patients developing a fulminant course with acute myocarditis","volume":"68","author":"Kato","year":"2004","journal-title":"Circulation J"},{"key":"10.1016\/j.amjmed.2019.10.015_bib0025","doi-asserted-by":"crossref","first-page":"1964","DOI":"10.1016\/j.jacc.2017.08.050","article-title":"Prognostic value of cardiac magnetic resonance tissue characterization in risk stratifying patients with suspected myocarditis","volume":"70","author":"Grani","year":"2017","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.amjmed.2019.10.015_bib0026","doi-asserted-by":"crossref","first-page":"1977","DOI":"10.1016\/j.jacc.2017.08.044","article-title":"Cardiac MR with late gadolinium enhancement in acute myocarditis with preserved systolic function: ITAMY Study","volume":"70","author":"Aquaro","year":"2017","journal-title":"J Am Coll Cardiol"}],"container-title":["The American Journal of Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000293431930957X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000293431930957X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T09:19:40Z","timestamp":1757582380000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S000293431930957X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4]]},"references-count":26,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,4]]}},"alternative-id":["S000293431930957X"],"URL":"https:\/\/doi.org\/10.1016\/j.amjmed.2019.10.015","relation":{},"ISSN":["0002-9343"],"issn-type":[{"value":"0002-9343","type":"print"}],"subject":[],"published":{"date-parts":[[2020,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Epidemiology Characteristics and Outcome of Patients With Clinically Diagnosed Acute Myocarditis","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.amjmed.2019.10.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}