{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T16:38:28Z","timestamp":1758040708825,"version":"3.44.0"},"reference-count":12,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["amjmed.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Medicine"],"published-print":{"date-parts":[[2021,11]]},"DOI":"10.1016\/j.amjmed.2021.04.002","type":"journal-article","created":{"date-parts":[[2021,4,20]],"date-time":"2021-04-20T19:59:20Z","timestamp":1618948760000},"page":"1307-1308","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["Strange Bedfellows: Migraine Headache and Patent Foramen Ovale"],"prefix":"10.1016","volume":"134","author":[{"given":"Joseph S.","family":"Alpert","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.amjmed.2021.04.002_bib0001","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1212\/WNL.0b013e3182a43b32","article-title":"Migraine prevalence, socioeconomic status, and social causation","volume":"81","author":"Stewart","year":"2013","journal-title":"Neurology"},{"key":"10.1016\/j.amjmed.2021.04.002_bib0002","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1016\/S0140-6736(15)60692-4","article-title":"Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990\u20132013: a systematic analysis for the Global Burden of Disease Study 2013","volume":"386","year":"2015","journal-title":"Lancet"},{"key":"10.1016\/j.amjmed.2021.04.002_bib0003","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1159\/000015875","article-title":"Migraine with aura and right-to-left shunt on transcranial Doppler: a case-control study","volume":"8","author":"Del Sette","year":"1998","journal-title":"Cerebrovasc Dis"},{"key":"10.1016\/j.amjmed.2021.04.002_bib0004","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1042\/cs1000215","article-title":"Relationship between migraine and cardiac and pulmonary right-to-left shunts","volume":"100","author":"Wilmshurst","year":"2001","journal-title":"Clin Sci (London)"},{"key":"10.1016\/j.amjmed.2021.04.002_bib0005","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/j.amjmed.2013.12.006","article-title":"Patent foramen ovale and migraine attacks: a systematic review","volume":"127","author":"Lip","year":"2014","journal-title":"Am J Med"},{"key":"10.1016\/j.amjmed.2021.04.002_bib0006","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.1212\/01.wnl.0000179800.73706.20","article-title":"Prevalence and size of directly detected patent foramen ovale in migraine with aura","volume":"65","author":"Schwerzmann","year":"2005","journal-title":"Neurology"},{"key":"10.1016\/j.amjmed.2021.04.002_bib0007","article-title":"The correlation between migraine and patent foramen ovale","volume":"1","author":"Liu","year":"2020","journal-title":"Front Neurol."},{"key":"10.1016\/j.amjmed.2021.04.002_bib0008","article-title":"The efficacy of percutaneous patent foramen ovale closure on migraine: a meta-analysis of randomized controlled trials and observational studies","author":"Zhang","year":"2021","journal-title":"Bio Med Res Int"},{"key":"10.1016\/j.amjmed.2021.04.002_bib0009","doi-asserted-by":"crossref","first-page":"2766","DOI":"10.1016\/j.jacc.2017.09.1105","article-title":"Percutaneous closure of patent foramen ovale in patients with migraine. The PREMIUM trial","volume":"70","author":"Tobias","year":"2017","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.amjmed.2021.04.002_bib0010","doi-asserted-by":"crossref","first-page":"2029","DOI":"10.1093\/eurheartj\/ehw027","article-title":"Percutaneous closure of patent foramen ovale in migraine with aura, a randomized controlled trial","volume":"37","author":"Mattle","year":"2016","journal-title":"Eur Heart J"},{"key":"10.1016\/j.amjmed.2021.04.002_bib0011","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1161\/CIRCULATIONAHA.107.727271","volume":"117","author":"Dowson","year":"2008","journal-title":"Circulation"},{"key":"10.1016\/j.amjmed.2021.04.002_bib0012","first-page":"209","article-title":"Effect of clopidogrel and aspirin vs aspirin alone on migraine headaches after transcatheter atrial septal defect closure. One-year results of the CANOA randomized clinical trial","volume":"6","author":"Wintzer-Wehekind","year":"2021","journal-title":"JAMA."}],"container-title":["The American Journal of Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002934321002217?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002934321002217?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T09:26:16Z","timestamp":1757582776000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002934321002217"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11]]},"references-count":12,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2021,11]]}},"alternative-id":["S0002934321002217"],"URL":"https:\/\/doi.org\/10.1016\/j.amjmed.2021.04.002","relation":{},"ISSN":["0002-9343"],"issn-type":[{"type":"print","value":"0002-9343"}],"subject":[],"published":{"date-parts":[[2021,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Strange Bedfellows: Migraine Headache and Patent Foramen Ovale","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.amjmed.2021.04.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}