{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T01:09:17Z","timestamp":1783472957189,"version":"3.55.0"},"reference-count":15,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000026","name":"National Institute on Drug Abuse","doi-asserted-by":"publisher","award":["R01\\u2010DA039192"],"award-info":[{"award-number":["R01\\u2010DA039192"]}],"id":[{"id":"10.13039\/100000026","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000052","name":"NIH Office of the Director","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000052","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009633","name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009633","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000124","name":"Office of Research on Womens Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000124","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["amjmed.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Medicine"],"published-print":{"date-parts":[[2022,7]]},"DOI":"10.1016\/j.amjmed.2022.01.032","type":"journal-article","created":{"date-parts":[[2022,2,6]],"date-time":"2022-02-06T10:09:01Z","timestamp":1644142141000},"page":"864-870.e3","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["Association of Medication-Assisted Therapy with New Onset of Cardiac Arrhythmia in Patients Diagnosed with Opioid Use Disorders"],"prefix":"10.1016","volume":"135","author":[{"given":"Mukaila A.","family":"Raji","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shivani","family":"Priyadarshni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoying","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Biai","family":"Digbeu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong-Fang","family":"Kuo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.amjmed.2022.01.032_bib0001","unstructured":"Ahmad FB, Rossen LM, Sutton P. Provisional drug overdose death counts. National Center for Health Statistics. 2021. Available at: https:\/\/www.cdc.gov\/nchs\/nvss\/vsrr\/drug-overdose-data.htm. Accessed February 28, 2022."},{"issue":"1","key":"10.1016\/j.amjmed.2022.01.032_bib0002","doi-asserted-by":"crossref","first-page":"59","DOI":"10.7326\/M20-1210","article-title":"When epidemics collide: Coronavirus disease 2019 (COVID-19) and the opioid crisis","volume":"173","author":"Becker","year":"2020","journal-title":"Ann Intern Med."},{"issue":"3","key":"10.1016\/j.amjmed.2022.01.032_bib0003","doi-asserted-by":"crossref","first-page":"137","DOI":"10.7326\/M17-3107","article-title":"Medication for opioid use disorder after nonfatal opioid overdose and association with mortality: a cohort study","volume":"169","author":"Larochelle","year":"2018","journal-title":"Ann Intern Med"},{"issue":"2","key":"10.1016\/j.amjmed.2022.01.032_bib0004","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2019.20622","article-title":"Comparative effectiveness of different treatment pathways for opioid use disorder","volume":"3","author":"Wakeman","year":"2020","journal-title":"JAMA Netw Open"},{"issue":"11","key":"10.1016\/j.amjmed.2022.01.032_bib0005","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1001\/jamapsychiatry.2020.1511","article-title":"Methadone for opioid use disorder\u2013decades of effectiveness but still miles away in the US","volume":"77","author":"Joudrey","year":"2020","journal-title":"JAMA Psychiatry"},{"issue":"3","key":"10.1016\/j.amjmed.2022.01.032_bib0006","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1080\/08897077.2018.1488336","article-title":"Barriers to accessing treatment for pregnant women with opioid use disorder in Appalachian states","volume":"40","author":"Patrick","year":"2019","journal-title":"Subst Abus"},{"issue":"1","key":"10.1016\/j.amjmed.2022.01.032_bib0007","doi-asserted-by":"crossref","first-page":"1","DOI":"10.7326\/M18-3457","article-title":"Access to office-based buprenorphine treatment in areas with high rates of opioid-related mortality: an audit study","volume":"171","author":"Beetham","year":"2019","journal-title":"Ann Intern Med."},{"issue":"6","key":"10.1016\/j.amjmed.2022.01.032_bib0008","article-title":"QTc interval screening for cardiac risk in methadone treatment of opioid dependence","author":"Pani","year":"2013","journal-title":"Cochrane Database Syst Rev"},{"issue":"2","key":"10.1016\/j.amjmed.2022.01.032_bib0009","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.jacc.2020.11.002","article-title":"Cardiovascular complications of opioid use: JACC State-of-the-Art Review","volume":"77","author":"Krantz","year":"2021","journal-title":"J Am Coll Cardiol"},{"issue":"22","key":"10.1016\/j.amjmed.2022.01.032_bib0010","doi-asserted-by":"crossref","first-page":"2063","DOI":"10.1056\/NEJMp1402780","article-title":"Medication-assisted therapies\u2013tackling the opioid-overdose epidemic","volume":"370","author":"Volkow","year":"2014","journal-title":"N Engl J Med."},{"issue":"6 suppl 3","key":"10.1016\/j.amjmed.2022.01.032_bib0011","doi-asserted-by":"crossref","first-page":"S230","DOI":"10.1016\/j.amepre.2017.12.022","article-title":"Policy pathways to address provider workforce barriers to buprenorphine treatment","volume":"54","author":"Haffajee","year":"2018","journal-title":"Am J Prev Med."},{"issue":"14","key":"10.1016\/j.amjmed.2022.01.032_bib0012","doi-asserted-by":"crossref","first-page":"1515","DOI":"10.1001\/jama.2015.10345","article-title":"Changes in substance abuse treatment use among individuals with opioid use disorders in the United States, 2004\u20132013","volume":"314","author":"Saloner","year":"2015","journal-title":"JAMA"},{"key":"10.1016\/j.amjmed.2022.01.032_bib0013","doi-asserted-by":"crossref","DOI":"10.1016\/j.jsat.2021.108282","article-title":"Overdose deaths from nonprescribed prescription opioids, heroin, and other synthetic opioids in Medicare beneficiaries","volume":"124","author":"Kuo","year":"2021","journal-title":"J Subst Abuse Treat"},{"key":"10.1016\/j.amjmed.2022.01.032_bib0014","series-title":"Medications for Opioid Use Disorder Save Lives","year":"2019"},{"issue":"5","key":"10.1016\/j.amjmed.2022.01.032_bib0015","first-page":"596","article-title":"Removal of prior authorization for medication-assisted treatment: impact on opioid use and policy implications in a Medicare Advantage population","volume":"27","author":"Ferries","year":"2021","journal-title":"J Manag Care Spec Pharm"}],"container-title":["The American Journal of Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000293432200095X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000293432200095X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T17:51:33Z","timestamp":1777398693000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S000293432200095X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7]]},"references-count":15,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2022,7]]}},"alternative-id":["S000293432200095X"],"URL":"https:\/\/doi.org\/10.1016\/j.amjmed.2022.01.032","relation":{},"ISSN":["0002-9343"],"issn-type":[{"value":"0002-9343","type":"print"}],"subject":[],"published":{"date-parts":[[2022,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Association of Medication-Assisted Therapy with New Onset of Cardiac Arrhythmia in Patients Diagnosed with Opioid Use Disorders","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.amjmed.2022.01.032","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}