{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T18:15:19Z","timestamp":1789064119084,"version":"build-2803163510"},"reference-count":33,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,8,26]],"date-time":"2023-08-26T00:00:00Z","timestamp":1693008000000},"content-version":"am","delay-in-days":359,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["K23 HL153774"],"award-info":[{"award-number":["K23 HL153774"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["amjmed.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Medicine"],"published-print":{"date-parts":[[2022,9]]},"DOI":"10.1016\/j.amjmed.2022.04.012","type":"journal-article","created":{"date-parts":[[2022,4,25]],"date-time":"2022-04-25T20:42:20Z","timestamp":1650919340000},"page":"1093-1100.e2","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"title":["Burden of Microvascular Disease and Risk of Atrial Fibrillation in Adults with Type 2 Diabetes"],"prefix":"10.1016","volume":"135","author":[{"given":"Arnaud D.","family":"Kaze","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew F.","family":"Yuyun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregg C.","family":"Fonarow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8460-1617","authenticated-orcid":false,"given":"Justin B.","family":"Echouffo-Tcheugui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"18","key":"10.1016\/j.amjmed.2022.04.012_bib0001","doi-asserted-by":"crossref","first-page":"2370","DOI":"10.1001\/jama.285.18.2370","article-title":"Prevalence of diagnosed atrial fibrillation in adults: national implications for rhythm management and stroke prevention: the AnTicoagulation and Risk Factors in Atrial Fibrillation (ATRIA) Study","volume":"285","author":"Go","year":"2001","journal-title":"JAMA"},{"issue":"1","key":"10.1016\/j.amjmed.2022.04.012_bib0002","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.amjcard.2011.03.004","article-title":"Meta-analysis of cohort and case-control studies of type 2 diabetes mellitus and risk of atrial fibrillation","volume":"108","author":"Huxley","year":"2011","journal-title":"Am J Cardiol"},{"issue":"8","key":"10.1016\/j.amjmed.2022.04.012_bib0003","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1007\/s11606-010-1340-y","article-title":"Diabetes mellitus, glycemic control, and risk of atrial fibrillation","volume":"25","author":"Dublin","year":"2010","journal-title":"J Gen Intern Med"},{"issue":"1","key":"10.1016\/j.amjmed.2022.04.012_bib0004","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1111\/j.1538-7836.2010.04085.x","article-title":"A comparison of risk stratification schemes for stroke in 79,884 atrial fibrillation patients in general practice","volume":"9","author":"Van Staa","year":"2011","journal-title":"J Thromb Haemost"},{"issue":"11","key":"10.1016\/j.amjmed.2022.04.012_bib0005","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1016\/j.jacc.2017.07.755","article-title":"Care patterns and outcomes in atrial fibrillation patients with and without diabetes: ORBIT-AF Registry","volume":"70","author":"Echouffo-Tcheugui","year":"2017","journal-title":"J Am Coll Cardiol"},{"issue":"4","key":"10.1016\/j.amjmed.2022.04.012_bib0006","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1001\/jamacardio.2016.5224","article-title":"Atrial fibrillation, type 2 diabetes, and non-vitamin K antagonist oral anticoagulants: a review","volume":"2","author":"Plitt","year":"2017","journal-title":"JAMA Cardiol"},{"issue":"4","key":"10.1016\/j.amjmed.2022.04.012_bib0007","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1111\/j.1540-8167.2007.01037.x","article-title":"AGEs-RAGE system mediates atrial structural remodeling in the diabetic rat","volume":"19","author":"Kato","year":"2008","journal-title":"J Cardiovasc Electrophysiol"},{"key":"10.1016\/j.amjmed.2022.04.012_bib0008","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.carpath.2016.12.001","article-title":"Role of atrial endothelial cells in the development of atrial fibrosis and fibrillation in response to pressure overload","volume":"27","author":"Kume","year":"2017","journal-title":"Cardiovasc Pathol"},{"issue":"1","key":"10.1016\/j.amjmed.2022.04.012_bib0009","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/s12933-019-0983-1","article-title":"Risk of atrial fibrillation in persons with type 2 diabetes and the excess risk in relation to glycaemic control and renal function: a Swedish cohort study","volume":"19","author":"Seyed Ahmadi","year":"2020","journal-title":"Cardiovasc Diabetol"},{"issue":"8","key":"10.1016\/j.amjmed.2022.04.012_bib0010","doi-asserted-by":"crossref","first-page":"573","DOI":"10.7326\/0003-4819-147-8-200710160-00010","article-title":"The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies","volume":"147","author":"von Elm","year":"2007","journal-title":"Ann Intern Med"},{"issue":"12A","key":"10.1016\/j.amjmed.2022.04.012_bib0011","doi-asserted-by":"crossref","first-page":"21i","DOI":"10.1016\/j.amjcard.2007.03.003","article-title":"Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial: design and methods","volume":"99","author":"Buse","year":"2007","journal-title":"Am J Cardiol"},{"issue":"12A","key":"10.1016\/j.amjmed.2022.04.012_bib0012","doi-asserted-by":"crossref","first-page":"103i","DOI":"10.1016\/j.amjcard.2007.03.028","article-title":"Rationale, design, and methods of the Action to Control Cardiovascular Risk in Diabetes Eye Study (ACCORD-EYE)","volume":"99","author":"Chew","year":"2007","journal-title":"Am J Cardiol"},{"issue":"9739","key":"10.1016\/j.amjmed.2022.04.012_bib0013","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/S0140-6736(10)60576-4","article-title":"Effect of intensive treatment of hyperglycaemia on microvascular outcomes in type 2 diabetes: an analysis of the ACCORD randomised trial","volume":"376","author":"Ismail-Beigi","year":"2010","journal-title":"Lancet"},{"issue":"9","key":"10.1016\/j.amjmed.2022.04.012_bib0014","doi-asserted-by":"crossref","first-page":"604","DOI":"10.7326\/0003-4819-150-9-200905050-00006","article-title":"A new equation to estimate glomerular filtration rate","volume":"150","author":"Levey","year":"2009","journal-title":"Ann Intern Med"},{"issue":"7","key":"10.1016\/j.amjmed.2022.04.012_bib0015","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1111\/j.1464-5491.2012.03644.x","article-title":"Use of the Michigan Neuropathy Screening Instrument as a measure of distal symmetrical peripheral neuropathy in Type 1 diabetes: results from the Diabetes Control and Complications Trial\/Epidemiology of Diabetes Interventions and Complications","volume":"29","author":"Herman","year":"2012","journal-title":"Diabet Med"},{"issue":"5 suppl","key":"10.1016\/j.amjmed.2022.04.012_bib0016","first-page":"823","article-title":"Fundus photographic risk factors for progression of diabetic retinopathy. ETDRS report number 12. Early Treatment Diabetic Retinopathy Study Research Group","volume":"98","year":"1991","journal-title":"Ophthalmology"},{"key":"10.1016\/j.amjmed.2022.04.012_bib0017","series-title":"The Minnesota Code Manual of Electrocardiographic Findings","author":"Prineas","year":"2009"},{"issue":"9","key":"10.1016\/j.amjmed.2022.04.012_bib0018","doi-asserted-by":"crossref","first-page":"1386","DOI":"10.2215\/CJN.01860217","article-title":"eGFR and albuminuria in relation to risk of incident atrial fibrillation: a meta-analysis of the Jackson Heart Study, the Multi-Ethnic Study of Atherosclerosis, and the Cardiovascular Health Study","volume":"12","author":"Bansal","year":"2017","journal-title":"Clin J Am Soc Nephrol"},{"issue":"7","key":"10.1016\/j.amjmed.2022.04.012_bib0019","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.117.005685","article-title":"Association of proteinuria and incident atrial fibrillation in patients with intact and reduced kidney function","volume":"6","author":"Molnar","year":"2017","journal-title":"J Am Heart Assoc"},{"issue":"6","key":"10.1016\/j.amjmed.2022.04.012_bib0020","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1016\/j.jdiacomp.2015.05.006","article-title":"Relationship between increased left atrial volume and microvascular complications in patients with type 2 diabetes","volume":"29","author":"Bonapace","year":"2015","journal-title":"J Diabetes Complications"},{"issue":"12","key":"10.1016\/j.amjmed.2022.04.012_bib0021","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1093\/ehjci\/jes084","article-title":"Changes in left atrial volume in diabetes mellitus: more than diastolic dysfunction?","volume":"13","author":"Kadappu","year":"2012","journal-title":"Eur Heart J Cardiovasc Imaging"},{"issue":"3","key":"10.1016\/j.amjmed.2022.04.012_bib0022","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.jacc.2016.10.059","article-title":"Cardiac autonomic dysfunction and incidence of atrial fibrillation: results from 20 years follow-up","volume":"69","author":"Agarwal","year":"2017","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.amjmed.2022.04.012_bib0023","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1016\/j.ijcard.2016.08.296","article-title":"Evaluation of the association between diabetic retinopathy and the incidence of atrial fibrillation: a nationwide population-based study","volume":"223","author":"Lee","year":"2016","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.amjmed.2022.04.012_bib0024","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.ijcard.2014.10.102","article-title":"Relationship between macular and retinal diseases with prevalent atrial fibrillation - an analysis of the Australian Heart Eye Study","volume":"178","author":"Phan","year":"2015","journal-title":"Int J Cardiol"},{"issue":"3","key":"10.1016\/j.amjmed.2022.04.012_bib0025","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1007\/s10741-011-9257-z","article-title":"Diabetic cardiomyopathy: understanding the molecular and cellular basis to progress in diagnosis and treatment","volume":"17","author":"Falc\u00e3o-Pires","year":"2012","journal-title":"Heart Fail Rev"},{"issue":"24","key":"10.1016\/j.amjmed.2022.04.012_bib0026","doi-asserted-by":"crossref","first-page":"2459","DOI":"10.1161\/CIRCULATIONAHA.116.022194","article-title":"Clinical update: cardiovascular disease in diabetes mellitus: atherosclerotic cardiovascular disease and heart failure in type 2 diabetes mellitus - mechanisms, management, and clinical considerations","volume":"133","author":"Low Wang","year":"2016","journal-title":"Circulation"},{"issue":"8","key":"10.1016\/j.amjmed.2022.04.012_bib0027","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1136\/hrt.2005.068270","article-title":"Oxidative stress and redox signalling in cardiac hypertrophy and heart failure","volume":"93","author":"Seddon","year":"2007","journal-title":"Heart"},{"issue":"16","key":"10.1016\/j.amjmed.2022.04.012_bib0028","doi-asserted-by":"crossref","first-page":"1302","DOI":"10.1136\/heartjnl-2015-307438","article-title":"Association between diastolic dysfunction and future atrial fibrillation in the Troms\u00f8 Study from 1994 to 2010","volume":"101","author":"Tiwari","year":"2015","journal-title":"Heart"},{"issue":"5","key":"10.1016\/j.amjmed.2022.04.012_bib0029","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1111\/joim.12492","article-title":"Current controversies in determining the main mechanisms of atrial fibrillation","volume":"279","author":"Schotten","year":"2016","journal-title":"J Intern Med"},{"issue":"8","key":"10.1016\/j.amjmed.2022.04.012_bib0030","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1016\/j.jacc.2019.07.020","article-title":"Atrial fibrillation and diabetes mellitus: JACC review topic of the week","volume":"74","author":"Wang","year":"2019","journal-title":"J Am Coll Cardiol"},{"issue":"1","key":"10.1016\/j.amjmed.2022.04.012_bib0031","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jacc.2015.04.058","article-title":"Electrophysiological, electroanatomical, and structural remodeling of the atria as consequences of sustained obesity","volume":"66","author":"Mahajan","year":"2015","journal-title":"J Am Coll Cardiol"},{"issue":"5","key":"10.1016\/j.amjmed.2022.04.012_bib0032","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1536\/ihj.50.627","article-title":"Influences of autonomic nervous system on atrial arrhythmogenic substrates and the incidence of atrial fibrillation in diabetic heart","volume":"50","author":"Otake","year":"2009","journal-title":"Int Heart J"},{"issue":"1","key":"10.1016\/j.amjmed.2022.04.012_bib0033","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCEP.120.008997","article-title":"Performance of atrial fibrillation risk prediction models in over 4 million individuals","volume":"14","author":"Khurshid","year":"2021","journal-title":"Circ Arrhythm Electrophysiol"}],"container-title":["The American Journal of Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000293432200331X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000293432200331X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T09:27:34Z","timestamp":1757582854000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S000293432200331X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9]]},"references-count":33,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2022,9]]}},"alternative-id":["S000293432200331X"],"URL":"https:\/\/doi.org\/10.1016\/j.amjmed.2022.04.012","relation":{},"ISSN":["0002-9343"],"issn-type":[{"value":"0002-9343","type":"print"}],"subject":[],"published":{"date-parts":[[2022,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Burden of Microvascular Disease and Risk of Atrial Fibrillation in Adults with Type 2 Diabetes","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.amjmed.2022.04.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}