{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T20:54:58Z","timestamp":1792616098636,"version":"4.5.0"},"reference-count":30,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T00:00:00Z","timestamp":1792540800000},"content-version":"vor","delay-in-days":50,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["amjmed.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Medicine"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1016\/j.amjmed.2026.08.021","type":"journal-article","created":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T15:30:50Z","timestamp":1789572650000},"update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Drawing a line between integrative and functional medicine"],"prefix":"10.1016","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1641-3136","authenticated-orcid":false,"given":"Gary K.","family":"Soffer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9935-6888","authenticated-orcid":false,"given":"Michelle","family":"Loy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-9135-4337","authenticated-orcid":false,"given":"Steve","family":"Bierman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0377-7822","authenticated-orcid":false,"given":"Andrew","family":"Weil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.amjmed.2026.08.021_bib0001","series-title":"Complementary, Alternative, or Integrative Health: what\u2019s in a Name?","year":"2026"},{"issue":"5","key":"10.1016\/j.amjmed.2026.08.021_bib0002","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/j.explore.2009.06.008","article-title":"Integrative medicine and patient-centered care","volume":"5","author":"Maizes","year":"2009","journal-title":"Explore"},{"issue":"6","key":"10.1016\/j.amjmed.2026.08.021_bib0003","doi-asserted-by":"crossref","first-page":"1374","DOI":"10.1542\/peds.2008-2173","article-title":"Task force on complementary and alternative medicine; provisional section on complementary, holistic, and integrative medicine. The use of complementary and alternative medicine in pediatrics","volume":"122","author":"Kemper","year":"2008","journal-title":"Pediatrics"},{"issue":"2","key":"10.1016\/j.amjmed.2026.08.021_bib0004","first-page":"22","article-title":"Functional medicine past, present, and future","volume":"21","author":"Bland","year":"2022","journal-title":"Integr Med"},{"issue":"1","key":"10.1016\/j.amjmed.2026.08.021_bib0005","first-page":"22","article-title":"Defining function in the functional medicine model","volume":"16","author":"Bland","year":"2017","journal-title":"Integr Med"},{"key":"10.1016\/j.amjmed.2026.08.021_bib0006","doi-asserted-by":"crossref","DOI":"10.1155\/2017\/1718957","article-title":"A systems medicine approach: translating emerging science into individualized wellness","volume":"2017","author":"Bland","year":"2017","journal-title":"Adv Med"},{"key":"10.1016\/j.amjmed.2026.08.021_bib0007","unstructured":"Institute for Functional Medicine. IFM releases 2025 impact report highlighting global growth, expanded access, and advancement of functional medicine. Published May 15, 2026. Accessed August 4, 2026."},{"key":"10.1016\/j.amjmed.2026.08.021_bib0008","unstructured":"Institute for Functional Medicine. IFM\u2019s functional medicine matrix: organizing clinical imbalances. Updated October 17, 2025. Accessed August 4, 2026."},{"issue":"1","key":"10.1016\/j.amjmed.2026.08.021_bib0009","doi-asserted-by":"crossref","first-page":"76","DOI":"10.4300\/JGME-04-01-30","article-title":"Integrative medicine in residency education: developing competency through online curriculum training","volume":"4","author":"Lebensohn","year":"2012","journal-title":"J Gr Med Educ"},{"issue":"3","key":"10.1016\/j.amjmed.2026.08.021_bib0010","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1097\/ACM.0000000000000148","article-title":"Developing and implementing core competencies for integrative medicine fellowships","volume":"89","author":"Ring","year":"2014","journal-title":"Acad Med"},{"key":"10.1016\/j.amjmed.2026.08.021_bib0011","unstructured":"Academic Consortium for Integrative Medicine & Health. Member listing. Accessed August 4, 2026."},{"key":"10.1016\/j.amjmed.2026.08.021_bib0012","unstructured":"American Board of Physician Specialties. Integrative medicine eligibility. Accessed August 4, 2026."},{"key":"10.1016\/j.amjmed.2026.08.021_bib0013","unstructured":"Academic Consortium for Integrative Medicine & Health. Fellowship recognition. Accessed August 4, 2026."},{"key":"10.1016\/j.amjmed.2026.08.021_bib0014","unstructured":"Institute for Functional Medicine. Are IFM\u2019s courses required for certification? Accessed August 4, 2026."},{"key":"10.1016\/j.amjmed.2026.08.021_bib0015","unstructured":"Institute for Functional Medicine. IFM establishes the first certifying board for the functional medicine field. Published September 16, 2025. Accessed August 4, 2026."},{"key":"10.1016\/j.amjmed.2026.08.021_bib0016","unstructured":"Institute for Functional Medicine. Functional medicine certification program. Accessed August 4, 2026."},{"key":"10.1016\/j.amjmed.2026.08.021_bib0017","unstructured":"Academic Consortium for Integrative Medicine & Health. Research. Accessed August 4, 2026."},{"key":"10.1016\/j.amjmed.2026.08.021_bib0018","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1186\/s12906-016-1025-0","article-title":"Patients receiving Integrative Medicine Effectiveness Registry (PRIMIER) of the BraveNet practice-based research network: study protocol","volume":"16","author":"Dusek","year":"2015","journal-title":"BMC Complement Altern Med"},{"key":"10.1016\/j.amjmed.2026.08.021_bib0019","unstructured":"Osher Collaborative for Integrative Health. About the osher collaborative. Accessed August 4, 2026."},{"issue":"13","key":"10.1016\/j.amjmed.2026.08.021_bib0020","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1001\/jama.2014.10186","article-title":"The connection between evidence-based medicine and shared decision making","volume":"312","author":"Hoffmann","year":"2014","journal-title":"JAMA"},{"issue":"10092","key":"10.1016\/j.amjmed.2026.08.021_bib0021","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/S0140-6736(16)31592-6","article-title":"Progress in evidence-based medicine: a quarter century on","volume":"390","author":"Djulbegovic","year":"2017","journal-title":"Lancet"},{"issue":"10","key":"10.1016\/j.amjmed.2026.08.021_bib0022","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2019.14017","article-title":"Association of the functional medicine model of care with patient-reported health-related quality-of-life outcomes","volume":"2","author":"Beidelschies","year":"2019","journal-title":"JAMA Netw Open"},{"issue":"1","key":"10.1016\/j.amjmed.2026.08.021_bib0023","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1186\/s12902-016-0128-4","article-title":"Adrenal fatigue does not exist: a systematic review","volume":"16","author":"Cadegiani","year":"2016","journal-title":"BMC Endocr Disord"},{"issue":"7","key":"10.1016\/j.amjmed.2026.08.021_bib0024","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1111\/j.1398-9995.2008.01705.x","article-title":"Testing for IgG4 against foods is not recommended as a diagnostic tool: EAACI task force report","volume":"63","author":"Stapel","year":"2008","journal-title":"Allergy"},{"key":"10.1016\/j.amjmed.2026.08.021_bib0025","unstructured":"American Academy of Allergy, Asthma & Immunology. The myth of IgG food panel testing. Accessed August 4, 2026."},{"issue":"9","key":"10.1016\/j.amjmed.2026.08.021_bib0026","doi-asserted-by":"crossref","first-page":"1601","DOI":"10.1002\/art.1780400909","article-title":"Range of antinuclear antibodies in \u201chealthy\u201d individuals","volume":"40","author":"Tan","year":"1997","journal-title":"Arthritis Rheum"},{"issue":"3","key":"10.1016\/j.amjmed.2026.08.021_bib0027","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.autrev.2015.12.002","article-title":"Choosing wisely: review and commentary on anti-nuclear antibody (ANA) testing","volume":"15","author":"Fritzler","year":"2016","journal-title":"Autoimmun Rev"},{"issue":"8","key":"10.1016\/j.amjmed.2026.08.021_bib0028","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1056\/NEJM198602203140809","article-title":"The cascade effect in the clinical care of patients","volume":"314","author":"Mold","year":"1986","journal-title":"N Engl J Med"},{"issue":"5","key":"10.1016\/j.amjmed.2026.08.021_bib0029","first-page":"178","article-title":"Stopping the flood: reducing harmful cascades of care","volume":"27","author":"Chandrashekar","year":"2021","journal-title":"Am J Manag Care"},{"issue":"8","key":"10.1016\/j.amjmed.2026.08.021_bib0030","doi-asserted-by":"crossref","first-page":"1494","DOI":"10.1007\/s11606-019-05002-w","article-title":"Prevalence and correlates of medical financial hardship in the USA","volume":"34","author":"Yabroff","year":"2019","journal-title":"J Gen Intern Med"}],"container-title":["The American Journal of Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002934326006534?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002934326006534?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T20:23:44Z","timestamp":1792614224000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002934326006534"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":30,"alternative-id":["S0002934326006534"],"URL":"https:\/\/doi.org\/10.1016\/j.amjmed.2026.08.021","relation":{},"ISSN":["0002-9343"],"issn-type":[{"value":"0002-9343","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Drawing a line between integrative and functional medicine","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.amjmed.2026.08.021","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}