{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T01:21:12Z","timestamp":1792718472943,"version":"4.5.0"},"reference-count":112,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","amjmedsci.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of the Medical Sciences"],"published-print":{"date-parts":[[2018,1]]},"DOI":"10.1016\/j.amjms.2017.06.007","type":"journal-article","created":{"date-parts":[[2017,6,16]],"date-time":"2017-06-16T12:15:21Z","timestamp":1497615321000},"page":"67-75","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":36,"title":["Is Myc an Important Biomarker? Myc Expression in Immune Disorders and Cancer"],"prefix":"10.1016","volume":"355","author":[{"given":"Shivtia","family":"Trop-Steinberg","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yehudit","family":"Azar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.amjms.2017.06.007_bib1","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.7150\/ijbs.10190","article-title":"Small molecules targeting c-Myc oncogene: promising anti-cancer therapeutics","volume":"10","author":"Chen","year":"2014","journal-title":"Int J Biol Sci"},{"key":"10.1016\/j.amjms.2017.06.007_bib2","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.cell.2012.03.003","article-title":"MYC on the path to cancer","volume":"149","author":"Dang","year":"2012","journal-title":"Cell"},{"key":"10.1016\/j.amjms.2017.06.007_bib3","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1158\/1541-7786.MCR-13-0536","article-title":"The N-myconcogene: maximizing its targets, regulation, and therapeutic potential","volume":"12","author":"Beltran","year":"2014","journal-title":"Mol Cancer Res"},{"key":"10.1016\/j.amjms.2017.06.007_bib4","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1038\/nrc3984","article-title":"MYC: connecting selective transcriptional control to global RNA production","volume":"15","author":"Kress","year":"2015","journal-title":"Nat Rev Cancer"},{"key":"10.1016\/j.amjms.2017.06.007_bib5","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1016\/S1097-2765(02)00522-1","article-title":"E2F1 and c-Myc potentiate apoptosis through inhibition of NF-kappaB activity that facilitates MnSOD-mediated ROS elimination","volume":"9","author":"Tanaka","year":"2002","journal-title":"Mol Cell"},{"key":"10.1016\/j.amjms.2017.06.007_bib6","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1002\/eji.1830161006","article-title":"Modulation of c-fos and c-Myc mRNA levels in normal human lymphocytes by calcium ionophore A23187 and phorbol ester","volume":"16","author":"Grausz","year":"1986","journal-title":"Eur J Immunol"},{"key":"10.1016\/j.amjms.2017.06.007_bib7","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.cell.2012.08.033","article-title":"c-Myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cells","volume":"151","author":"Nie","year":"2012","journal-title":"Cell"},{"key":"10.1016\/j.amjms.2017.06.007_bib8","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1006\/cimm.1999.1563","article-title":"Quantitative and qualitative signals determine T-cell cycle entry and progression","volume":"197","author":"Modiano","year":"1999","journal-title":"Cell Immunol"},{"key":"10.1016\/j.amjms.2017.06.007_bib9","doi-asserted-by":"crossref","first-page":"3548","DOI":"10.1128\/MCB.12.8.3548","article-title":"Comparative analysis of the intracellular localization of c-Myc, c-Fos, and replicative proteins during cell cycle progression","volume":"12","author":"Vriz","year":"1992","journal-title":"Mol Cell Biol"},{"key":"10.1016\/j.amjms.2017.06.007_bib10","doi-asserted-by":"crossref","first-page":"1","DOI":"10.12688\/f1000research.7879.1","article-title":"Strategically targeting MYC in cancer","volume":"5","author":"Posternak","year":"2016","journal-title":"F1000Res"},{"key":"10.1016\/j.amjms.2017.06.007_bib11","doi-asserted-by":"crossref","first-page":"103","DOI":"10.4161\/cc.1.2.108","article-title":"The restriction point of the cell cycle","volume":"1","author":"Blagosklonny","year":"2002","journal-title":"Cell Cycle"},{"key":"10.1016\/j.amjms.2017.06.007_bib12","doi-asserted-by":"crossref","first-page":"4507","DOI":"10.4161\/cc.22529","article-title":"The mysterious human epidermal cell cycle, or an oncogene-induced differentiation checkpoint","volume":"11","author":"Gandarillas","year":"2012","journal-title":"Cell Cycle"},{"key":"10.1016\/j.amjms.2017.06.007_bib13","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1101\/gad.1067003","article-title":"Genomic targets of the human c-myc protein","volume":"17","author":"Fernandez","year":"2003","journal-title":"Genes Dev"},{"key":"10.1016\/j.amjms.2017.06.007_bib14","doi-asserted-by":"crossref","first-page":"8164","DOI":"10.1073\/pnas.1332764100","article-title":"A global transcriptional regulatory role for c-myc in Burkitt\u2019s lymphoma cell","volume":"100","author":"Li","year":"2003","journal-title":"PNAS"},{"key":"10.1016\/j.amjms.2017.06.007_bib15","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.cell.2012.08.026","article-title":"Transcriptional amplification in tumor cells with elevated c-Myc","volume":"151","author":"Lin","year":"2012","journal-title":"Cell"},{"key":"10.1016\/j.amjms.2017.06.007_bib16","first-page":"1915","article-title":"Constitutive c-myc expression in an IL-3-dependent myeloid cell line suppresses cell cycle arrest and accelerates apoptosis","volume":"6","author":"Askew","year":"1991","journal-title":"Oncogene"},{"key":"10.1016\/j.amjms.2017.06.007_bib17","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1126\/science.1378649","article-title":"Role for c-myc in activation-induced apoptotic cell death in T cell hybridomas","volume":"257","author":"Shi","year":"1992","journal-title":"Science"},{"key":"10.1016\/j.amjms.2017.06.007_bib18","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/S0959-437X(05)80339-9","article-title":"The role of c-myc in cell growth","volume":"3","author":"Evan","year":"1993","journal-title":"CurrOpin Genet Dev"},{"key":"10.1016\/j.amjms.2017.06.007_bib19","doi-asserted-by":"crossref","first-page":"a014233","DOI":"10.1101\/cshperspect.a014233","article-title":"Cellular MYCro economics: balancing MYC function with MYC expression","volume":"3","author":"Levens","year":"2013","journal-title":"Cold Spring Harb Perspect Med"},{"key":"10.1016\/j.amjms.2017.06.007_bib20","doi-asserted-by":"crossref","first-page":"4908","DOI":"10.4161\/cc.9.24.14199","article-title":"Proteomic profiling of Myc-associated proteins","volume":"9","author":"Agrawal","year":"2010","journal-title":"Cell Cycle"},{"key":"10.1016\/j.amjms.2017.06.007_bib21","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.cell.2010.09.010","article-title":"A Myc network accounts for similarities between embryonic stem and cancer cell transcription programs","volume":"143","author":"Kim","year":"2010","journal-title":"Cell"},{"key":"10.1016\/j.amjms.2017.06.007_bib22","doi-asserted-by":"crossref","first-page":"4012","DOI":"10.1158\/0008-5472.CAN-15-1216","article-title":"The MYC-WDR5 nexus and cancer","volume":"75","author":"Thomas","year":"2015","journal-title":"Cancer Res"},{"key":"10.1016\/j.amjms.2017.06.007_bib23","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1158\/2159-8290.CD-15-0507","article-title":"MYC, metabolism, and cancer","volume":"5","author":"Stine","year":"2015","journal-title":"Cancer Discov"},{"key":"10.1016\/j.amjms.2017.06.007_bib24","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1016\/j.bbagrm.2014.03.013","article-title":"Myc and cell cycle control","volume":"1849","author":"Bretones","year":"2015","journal-title":"Biochim BiophysActa"},{"key":"10.1016\/j.amjms.2017.06.007_bib25","doi-asserted-by":"crossref","first-page":"2755","DOI":"10.1101\/gad.1712408","article-title":"Myc\u2019s broad reach","volume":"22","author":"Eilers","year":"2008","journal-title":"Genes Dev"},{"key":"10.1016\/j.amjms.2017.06.007_bib26","first-page":"397","article-title":"c-fos, c-myc and IL-2R mRNA expression in PHA activated T lymphocytes treated with a monoclonal anti-HLA class I antibody (MAb 01.65)","volume":"22","author":"Selvatici","year":"1990","journal-title":"Biochem Int"},{"key":"10.1016\/j.amjms.2017.06.007_bib27","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.4161\/cc.8.8.8126","article-title":"Inhibition of cell differentiation: a critical mechanism for MYC-mediated carcinogenesis?","volume":"8","author":"Le\u00f3n","year":"2009","journal-title":"Cell Cycle"},{"key":"10.1016\/j.amjms.2017.06.007_bib28","doi-asserted-by":"crossref","first-page":"592","DOI":"10.4161\/cc.10.4.14792","article-title":"Myc orchestrates a regulatory network required for the establishment and maintenance of pluripotency","volume":"10","author":"Smith","year":"2011","journal-title":"Cell Cycle"},{"key":"10.1016\/j.amjms.2017.06.007_bib29","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1016\/0145-2126(85)90304-2","article-title":"Study of the levels of expression of two oncogenes, c-myc and c-myb, in acute and chronic leukemias of both lymphoid and myeloid lineage","volume":"9","author":"Ferrari","year":"1985","journal-title":"Leuk Res"},{"key":"10.1016\/j.amjms.2017.06.007_bib30","doi-asserted-by":"crossref","first-page":"3569","DOI":"10.4049\/jimmunol.144.9.3569","article-title":"Decreased steady state c-myc mRNA in activated T cell cultures from old humans is caused by a smaller proportion of T cells that transcribe the c-myc gene","volume":"144","author":"Gamble","year":"1990","journal-title":"J Immunol"},{"key":"10.1016\/j.amjms.2017.06.007_bib31","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/j.ccr.2008.10.018","article-title":"Distinct thresholds govern Myc\u2019s biological output in vivo","volume":"14","author":"Murphy","year":"2008","journal-title":"Cancer Cell"},{"key":"10.1016\/j.amjms.2017.06.007_bib32","doi-asserted-by":"crossref","first-page":"5132","DOI":"10.1158\/0008-5472.CAN-07-6192","article-title":"Genomic and proteomic analysis reveals a threshold level of MYC required for tumor maintenance","volume":"8","author":"Shachaf","year":"2008","journal-title":"Cancer Res"},{"key":"10.1016\/j.amjms.2017.06.007_bib33","doi-asserted-by":"crossref","first-page":"2119","DOI":"10.1038\/sj.emboj.7601101","article-title":"The FUSE\/FBP\/FIR\/TFIIH system is a molecular machine programming a pulse of c-myc expression","volume":"5","author":"Liu","year":"2006","journal-title":"EMBO J"},{"key":"10.1016\/j.amjms.2017.06.007_bib34","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/S0065-230X(07)99004-1","article-title":"The c-myc promoter: still Myster Y and challenge","volume":"99","author":"Wierstra","year":"2008","journal-title":"Adv Cancer Res"},{"key":"10.1016\/j.amjms.2017.06.007_bib35","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1038\/ng.2468","article-title":"The genetic landscape of mutations in Burkitt lymphoma","volume":"44","author":"Love","year":"2012","journal-title":"Nat Genet"},{"key":"10.1016\/j.amjms.2017.06.007_bib36","doi-asserted-by":"crossref","first-page":"5595","DOI":"10.1038\/sj.onc.1204595","article-title":"Translocations involving c-myc and c-myc function","volume":"20","author":"Boxer","year":"2001","journal-title":"Oncogene"},{"key":"10.1016\/j.amjms.2017.06.007_bib37","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1111\/joim.12237","article-title":"Inactivation of MYC reverses tumorigenesis","volume":"276","author":"Li","year":"2014","journal-title":"J Intern Med"},{"key":"10.1016\/j.amjms.2017.06.007_bib38","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.cell.2012.03.003","article-title":"Review MYC on the path to cancer","volume":"149","author":"Dang","year":"2012","journal-title":"Cell"},{"key":"10.1016\/j.amjms.2017.06.007_bib39","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1101\/cshperspect.a014266","article-title":"Therapeutic strategies to inhibit MYC","volume":"4","author":"McKeown","year":"2014","journal-title":"Cold Spring Harb Perspect Med"},{"key":"10.1016\/j.amjms.2017.06.007_bib40","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1016\/j.immuni.2011.09.021","article-title":"The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation","volume":"35","author":"Wang","year":"2011","journal-title":"Immunity"},{"key":"10.1016\/j.amjms.2017.06.007_bib41","doi-asserted-by":"crossref","first-page":"3298","DOI":"10.1038\/sj.emboj.7601224","article-title":"Pemphigus vulgaris identifies plakoglobin as key suppressor of c-Myc in the skin","volume":"25","author":"Williamson","year":"2006","journal-title":"EMBO J"},{"key":"10.1016\/j.amjms.2017.06.007_bib42","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1038\/nrneurol.2016.44","article-title":"Myasthenia gravis\u2014autoantibody characteristics and their implications for therapy","volume":"12","author":"Gilhus","year":"2016","journal-title":"Nat Rev Neurol"},{"key":"10.1016\/j.amjms.2017.06.007_bib43","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1182\/blood-2011-02-339911","article-title":"Role of c-MYC in alternative activation of human macrophages and tumor-associated macrophage biology","volume":"119","author":"Pello","year":"2012","journal-title":"Blood"},{"key":"10.1016\/j.amjms.2017.06.007_bib44","doi-asserted-by":"crossref","first-page":"e1151991","DOI":"10.1080\/2162402X.2016.1151991","article-title":"Macrophages and c-Myc cross paths","volume":"5","author":"Pello","year":"2016","journal-title":"Oncoimmunology"},{"key":"10.1016\/j.amjms.2017.06.007_bib45","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1146\/annurev.immunol.021908.132532","article-title":"Alternative activation of macrophages: an immunologic functional perspective","volume":"27","author":"Martinez","year":"2009","journal-title":"Annu Rev Immunol"},{"key":"10.1016\/j.amjms.2017.06.007_bib46","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1038\/nri2448","article-title":"Exploring the full spectrum of macrophage activation","volume":"8","author":"Mosser","year":"2008","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.amjms.2017.06.007_bib47","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1038\/ni.1937","article-title":"Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm","volume":"11","author":"Biswas","year":"2010","journal-title":"Nat Immunol"},{"key":"10.1016\/j.amjms.2017.06.007_bib48","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.kjms.2012.08.001","article-title":"New insights into desmosome regulation and pemphigus blistering as a desmosome-remodeling disease","volume":"29","author":"Kitajima","year":"2013","journal-title":"Kaohsiung J Med Sci"},{"key":"10.1016\/j.amjms.2017.06.007_bib49","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1080\/08820130902943097","article-title":"Involvement of T(H)1\/T(H)2 cytokines in the pathogenesis of autoimmune skin disease\u2014pemphigus vulgaris","volume":"38","author":"Satyam","year":"2009","journal-title":"Immunol Invest"},{"key":"10.1016\/j.amjms.2017.06.007_bib50","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/j.cyto.2014.11.002","article-title":"The dual nature of interleukin-10 in pemphigus vulgaris","volume":"73","author":"Cho","year":"2015","journal-title":"Cytokine"},{"key":"10.1016\/j.amjms.2017.06.007_bib51","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1159\/000365946","article-title":"Comparison of CD163+ CD206+ M2 macrophages in the lesional skin of bullous pemphigoid and pemphigus vulgaris: the possible pathogenesis of bullous pemphigoid","volume":"229","author":"Furudate","year":"2014","journal-title":"Dermatology"},{"key":"10.1016\/j.amjms.2017.06.007_bib52","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1083\/jcb.149.2.503","article-title":"Plakoglobin suppresses epithelial proliferation and hair growth in vivo","volume":"149","author":"Charpentier","year":"2000","journal-title":"J Cell Biol"},{"key":"10.1016\/j.amjms.2017.06.007_bib53","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1056\/NEJM198205203062001","article-title":"Induction of pemphigus in neonatal mice by passive transfer of IgG from patients with the disease","volume":"306","author":"Anhalt","year":"1982","journal-title":"N Eng J Med"},{"key":"10.1016\/j.amjms.2017.06.007_bib54","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1111\/j.1365-3164.2007.00561.x","article-title":"Upregulation of c-myc may contribute to the pathogenesis of canine pemphigus vulgaris","volume":"118","author":"Williamson","year":"2007","journal-title":"Vet Derm"},{"key":"10.1016\/j.amjms.2017.06.007_bib55","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1111\/j.1600-0625.2009.00893.x","article-title":"An imbalance in Akt\/mTOR is involved in the apoptotic and acantholytic processes in a mouse model of pemphigus vulgaris","volume":"18","author":"Pretel","year":"2009","journal-title":"Exp Dermatol"},{"key":"10.1016\/j.amjms.2017.06.007_bib56","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1038\/nrc2328","article-title":"MYC in mammalian epidermis: how can an oncogene stimulate differentiation?","volume":"8","author":"Watt","year":"2008","journal-title":"Nat Rev Cancer"},{"key":"10.1016\/j.amjms.2017.06.007_bib57","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1111\/j.0022-202X.2004.23479.x","article-title":"Desmogleins 1 and 3 in the companion layer anchor mouse anagen hair to the follicle","volume":"123","author":"Hanakawa","year":"2004","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.amjms.2017.06.007_bib58","first-page":"346","article-title":"An adult passive transfer mouse model to study desmoglein 3 signaling in pemphigus vulgaris","volume":"132","author":"Schulze","year":"2012","journal-title":"See comment in PubMed Commons belowJ Invest Dermatol"},{"key":"10.1016\/j.amjms.2017.06.007_bib59","doi-asserted-by":"crossref","first-page":"e0119809","DOI":"10.1371\/journal.pone.0119809","article-title":"Preclinical studies identify non-apoptotic low-level caspase-3 as therapeutic target in pemphigus vulgaris","volume":"10","author":"Luyet","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.amjms.2017.06.007_bib60","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1111\/j.1600-0536.1994.tb02019.x","article-title":"The modulation of skin irritation","volume":"31","author":"Berardesca","year":"1994","journal-title":"Contact Derm"},{"key":"10.1016\/j.amjms.2017.06.007_bib61","first-page":"341","article-title":"Overview of psoriasis","volume":"17","author":"DeRie","year":"2004","journal-title":"Dermatol Ther"},{"key":"10.1016\/j.amjms.2017.06.007_bib62","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1038\/sj.jid.5700735","article-title":"Nuclear c-Myc a molecular marker of early stage pemphigus vulgaris","volume":"127","author":"Williamson","year":"2007","journal-title":"J of Invest Derma"},{"key":"10.1016\/j.amjms.2017.06.007_bib63","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1007\/s12016-016-8549-4","article-title":"Review on toll-like receptor activation in myasthenia gravis: application to the development of new experimental models","volume":"52","author":"Robinet","year":"2017","journal-title":"Clin Rev Allergy Immunol"},{"key":"10.1016\/j.amjms.2017.06.007_bib64","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1016\/j.autrev.2013.03.010","article-title":"Etiology of myasthenia gravis: innate immunity signature in pathological thymus","volume":"12","author":"Cavalcante","year":"2013","journal-title":"Autoimmun Rev"},{"key":"10.1016\/j.amjms.2017.06.007_bib65","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.jaut.2013.12.013","article-title":"Innate immunity in myasthenia gravis thymus: pathogenic effects of toll-like receptor 4 signaling on autoimmunity","volume":"52","author":"Cordiglieri","year":"2014","journal-title":"J Autoimmun"},{"key":"10.1016\/j.amjms.2017.06.007_bib66","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/S0165-5728(01)00252-1","article-title":"Decreased expression of c-myc family genes in thymuses from myasthenia gravis patients","volume":"115","author":"Nagata","year":"2001","journal-title":"J Neuroimmunol"},{"key":"10.1016\/j.amjms.2017.06.007_bib67","doi-asserted-by":"crossref","first-page":"519","DOI":"10.2169\/internalmedicine.32.519","article-title":"Expression of c-myc, c-Ki-ras and c-Ha-ras oncogene products in peripheral blood mononuclear cells from patients with myasthenia gravis","volume":"32","author":"Arimori","year":"1993","journal-title":"Intern Med"},{"key":"10.1016\/j.amjms.2017.06.007_bib68","doi-asserted-by":"crossref","first-page":"3348","DOI":"10.4049\/jimmunol.1502385","article-title":"Transcriptional repression of IFN regulatory factor 7 by MYC is critical for type I IFN production in human plasmacytoid dendritic cells","volume":"197","author":"Kim","year":"2016","journal-title":"J Immunol"},{"key":"10.1016\/j.amjms.2017.06.007_bib69","first-page":"951","article-title":"Interferon system and natural killer cell activity in myasthenia gravis","volume":"76","author":"Kott","year":"1990","journal-title":"Q J Med"},{"key":"10.1016\/j.amjms.2017.06.007_bib70","first-page":"219","article-title":"Retrovirus-like particles in human thymomas","volume":"15","author":"Arimori","year":"1990","journal-title":"Tokai J ExpClin Med"},{"key":"10.1016\/j.amjms.2017.06.007_bib71","doi-asserted-by":"crossref","first-page":"1789","DOI":"10.4049\/jimmunol.131.4.1789","article-title":"Subpopulations of human natural killer cells defined by expression of the Leu-7 (HNK-1) and Leu-ll (NK-15) antigens","volume":"131","author":"Lanier","year":"1983","journal-title":"J Immunol"},{"key":"10.1016\/j.amjms.2017.06.007_bib72","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/s12920-015-0087-z","article-title":"Systems biology of myasthenia gravis, integration of aberrant lncRNA and mRNA expression changes","volume":"8","author":"Luo","year":"2015","journal-title":"BMC Med Genomics"},{"key":"10.1016\/j.amjms.2017.06.007_bib73","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1111\/jcmm.12243","article-title":"Analysing the relationship between lncRNA and protein-coding gene and the role of lncRNA as ceRNA in pulmonary fibrosis","volume":"18","author":"Song","year":"2014","journal-title":"J Cell Mol Med"},{"key":"10.1016\/j.amjms.2017.06.007_bib74","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.trim.2013.03.002","article-title":"Early cell-cycle gene expression in T-cells after hematopoietic stem cell transplantation","volume":"24","author":"Trop-Steinberg","year":"2013","journal-title":"Transpl Immuno"},{"key":"10.1016\/j.amjms.2017.06.007_bib75","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1007\/s10238-014-0285-6","article-title":"Myc and AP-1 expressionin T-cells and T-cell activation in patients after hematopoietic stem cell transplantation","volume":"15","author":"Trop-Steinberg","year":"2015","journal-title":"Clin Exp Med"},{"key":"10.1016\/j.amjms.2017.06.007_bib76","doi-asserted-by":"crossref","first-page":"139","DOI":"10.3109\/08916934.2015.1027815","article-title":"Macrophages in vascular inflammation: from atherosclerosis to vasculitis","volume":"48","author":"Shirai","year":"2015","journal-title":"Autoimmunity"},{"key":"10.1016\/j.amjms.2017.06.007_bib77","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1177\/0003319707303443","article-title":"Atherosclerosis pathophysiology and the role of novel risk factors: a clinicobiochemical perspective","volume":"58","author":"Mallika","year":"2007","journal-title":"Angiology"},{"key":"10.1016\/j.amjms.2017.06.007_bib78","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1002\/jcp.1041460304","article-title":"Induction of cell cycle-dependent genes during cell cycle progression of arterial smooth muscle cells in culture","volume":"146","author":"Gadeau","year":"1991","journal-title":"J Cell Physiol"},{"key":"10.1016\/j.amjms.2017.06.007_bib79","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1016\/0006-291X(91)91235-5","article-title":"Dissociation between activation of growth related genes and mitogenic responses of neonatal vascular smooth muscle cells","volume":"181","author":"Weiss","year":"1991","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.amjms.2017.06.007_bib80","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.4161\/cc.5.15.3138","article-title":"Targeting c-Myc, Ras and IGF cascade to treat cancer and vascular disorders","volume":"5","author":"de Nigris","year":"2006","journal-title":"Cell Cycle"},{"key":"10.1016\/j.amjms.2017.06.007_bib81","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1056\/NEJM198602203140806","article-title":"The pathogenesis of atherosclerosis: an update","volume":"314","author":"Ross","year":"1986","journal-title":"N Engl J Med"},{"key":"10.1016\/j.amjms.2017.06.007_bib82","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1056\/NEJM199201233260406","article-title":"The pathogenesis of coronary artery disease and the acute coronary syndrome","volume":"326","author":"Fuster","year":"1992","journal-title":"N Engl J Med"},{"key":"10.1016\/j.amjms.2017.06.007_bib83","first-page":"765","article-title":"Cultured human atherosclerotic plaque smooth muscle cells retain transforming potential and display expression of the MYC proto-oncogene","volume":"138","author":"Parkes","year":"1991","journal-title":"J Pathol"},{"key":"10.1016\/j.amjms.2017.06.007_bib84","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/0741-5214(93)90596-E","article-title":"Distribution of c-myc oncoprotein in healthy and atherosclerotic human carotid arteries","volume":"18","author":"Marin","year":"1993","journal-title":"J Vasc Surg"},{"key":"10.1016\/j.amjms.2017.06.007_bib85","doi-asserted-by":"crossref","first-page":"12865","DOI":"10.1016\/S0021-9258(18)67172-8","article-title":"Regulation of oncogene expression in cultured aortic smooth muscle cells","volume":"261","author":"Kindy","year":"1986","journal-title":"J Biol Chem"},{"key":"10.1016\/j.amjms.2017.06.007_bib86","first-page":"761","article-title":"Early proto-oncogene expression in rat aortic smooth muscle cells following endothelial removal","volume":"137","author":"Miano","year":"1990","journal-title":"Am J Pathol"},{"issue":"511","key":"10.1016\/j.amjms.2017.06.007_bib87","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1038\/nature13473","article-title":"Activation and repression by oncogenic MYC shape tumour-specific gene expression profiles","volume":"24","author":"Walz","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.amjms.2017.06.007_bib88","first-page":"423","article-title":"Cell cycle alterations and lung cancer","volume":"21","author":"Vincenzi","year":"2006","journal-title":"Histol Histopathol"},{"key":"10.1016\/j.amjms.2017.06.007_bib89","doi-asserted-by":"crossref","first-page":"6789","DOI":"10.1158\/1078-0432.CCR-04-0306","article-title":"Molecular profiling of inflammatory breast cancer: identification of a poor-prognosis gene expression signature","volume":"10","author":"Bi\u00e8che","year":"2004","journal-title":"Clin Canc Res"},{"key":"10.1016\/j.amjms.2017.06.007_bib90","doi-asserted-by":"crossref","first-page":"7331","DOI":"10.1073\/pnas.0832317100","article-title":"Transcriptional profiling of the sonic hedgehog response: a critical role for N-myc in proliferation of neuronal precursors","volume":"100","author":"Oliver","year":"2003","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.amjms.2017.06.007_bib91","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.maturitas.2008.11.010","article-title":"Oncogenic pathways in hereditary and sporadic breast cancer","volume":"61","author":"Kenemans","year":"2008","journal-title":"Maturitas"},{"key":"10.1016\/j.amjms.2017.06.007_bib92","doi-asserted-by":"crossref","first-page":"41","DOI":"10.3233\/CBM-2009-0570","article-title":"Frequent amplifications and deletions of G1\/S-phase transition genes, CCND1 and MYC in early breast cancers: a potential role in G1\/S escape","volume":"5","author":"Jensen","year":"2009","journal-title":"Cancer Biomark"},{"key":"10.1016\/j.amjms.2017.06.007_bib93","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1097\/00000658-199506000-00010","article-title":"Oncogene protein co-expression: value of Ha-ras, c-myc, c-fos, and p53 as prognostic discriminants for breast carcinoma","volume":"221","author":"Bland","year":"1995","journal-title":"Ann Surg"},{"key":"10.1016\/j.amjms.2017.06.007_bib94","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1007\/s10549-013-2600-4","article-title":"Inflammatory breast cancer (IBC): clues for targeted therapies","volume":"140","author":"Fernandez","year":"2013","journal-title":"Breast Cancer Res Treat"},{"key":"10.1016\/j.amjms.2017.06.007_bib95","doi-asserted-by":"crossref","first-page":"5143","DOI":"10.1158\/0008-5472.CAN-15-0423","article-title":"WDR5 Supports an N-Myc transcriptional complex that drives a protumorigenic gene expression signature in neuroblastoma","volume":"75","author":"Sun","year":"2015","journal-title":"Cancer Res"},{"key":"10.1016\/j.amjms.2017.06.007_bib96","doi-asserted-by":"crossref","first-page":"4985","DOI":"10.1038\/onc.2014.427","article-title":"c-MYC is a radiosensitive locus in human breast cells","volume":"34","author":"Wade","year":"2015","journal-title":"Oncogene"},{"key":"10.1016\/j.amjms.2017.06.007_bib97","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1186\/1748-717X-6-168","article-title":"Significance of genomic instability in breast cancer in atomic bomb survivors: analysis of microarray-comparative genomic hybridization","volume":"6","author":"Oikawa","year":"2011","journal-title":"Radiat Oncol"},{"key":"10.1016\/j.amjms.2017.06.007_bib98","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1016\/j.ijrobp.2009.09.004","article-title":"Radiation-associated breast tumors display a distinct gene expression profile","volume":"76","author":"Broeks","year":"2010","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.amjms.2017.06.007_bib99","doi-asserted-by":"crossref","first-page":"e9201","DOI":"10.1371\/journal.pone.0009201","article-title":"Delineating genetic alterations for tumor progression in the MCF10A series of breast cancer cell lines","volume":"5","author":"Kadota","year":"2010","journal-title":"PLoS One"},{"key":"10.1016\/j.amjms.2017.06.007_bib100","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/0090-8258(90)90069-W","article-title":"Myc amplification in ovarian cancer","volume":"38","author":"Baker","year":"1990","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.amjms.2017.06.007_bib101","doi-asserted-by":"crossref","first-page":"2260","DOI":"10.1158\/1535-7163.MCT-14-0801","article-title":"Targeting c-MYC in platinum-resistant ovarian cancer","volume":"14","author":"Reyes-Gonz\u00e1lez","year":"2015","journal-title":"Mol Cancer Ther"},{"key":"10.1016\/j.amjms.2017.06.007_bib102","doi-asserted-by":"crossref","first-page":"e89841","DOI":"10.1371\/journal.pone.0089841","article-title":"The inhibitory effect of doxycycline on cisplatin-sensitive and -resistant epithelial ovarian cancer","volume":"9","author":"Wu","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.amjms.2017.06.007_bib103","article-title":"Acute myeloid leukaemia: expression of MYC protein and its association with cytogenetic risk profile and overall survival","author":"Mughal","year":"2016","journal-title":"Hematol Oncol"},{"key":"10.1016\/j.amjms.2017.06.007_bib104","first-page":"5","article-title":"Acute myeloid leukemia: a concise review","author":"Saultz","year":"2016","journal-title":"J Clin Med"},{"key":"10.1016\/j.amjms.2017.06.007_bib105","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.bbrc.2015.07.123","article-title":"ADCY7 supports development of acute myeloid leukemia","volume":"465","author":"Li","year":"2015","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.amjms.2017.06.007_bib106","doi-asserted-by":"crossref","first-page":"197","DOI":"10.4082\/kjfm.2015.36.5.197","article-title":"An overview and update of chronic myeloid leukemia for primary care physicians","volume":"36","author":"Granatowicz","year":"2015","journal-title":"KoreanJ Fam Med"},{"key":"10.1016\/j.amjms.2017.06.007_bib107","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1186\/s12943-015-0407-0","article-title":"BCR\/ABL1 and BCR are under the transcriptional control of the MYC oncogene","volume":"14","author":"Sharma","year":"2015","journal-title":"Mol Cancer"},{"key":"10.1016\/j.amjms.2017.06.007_bib108","doi-asserted-by":"crossref","first-page":"1456","DOI":"10.1038\/sj.emboj.7601485","article-title":"Bcr-Abl stabilizes beta-catenin in chronic myeloid leukemia through its tyrosine phosphorylation","volume":"26","author":"Coluccia","year":"2007","journal-title":"EMBO J"},{"key":"10.1016\/j.amjms.2017.06.007_bib109","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1056\/NEJMoa040258","article-title":"Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML","volume":"351","author":"Jamieson","year":"2004","journal-title":"N Engl J Med"},{"key":"10.1016\/j.amjms.2017.06.007_bib110","doi-asserted-by":"crossref","first-page":"1574","DOI":"10.1016\/j.mayocp.2015.07.005","article-title":"Hodgkin lymphoma: diagnosis and treatment","volume":"90","author":"Ansell","year":"2015","journal-title":"Mayo Clin Proc"},{"key":"10.1016\/j.amjms.2017.06.007_bib111","doi-asserted-by":"crossref","first-page":"196","DOI":"10.6004\/jnccn.2016.0023","article-title":"Diffuse large B-cell lymphoma version 1.2016","volume":"14","author":"Zelenetz","year":"2016","journal-title":"J Natl Compr Canc Netw"},{"key":"10.1016\/j.amjms.2017.06.007_bib112","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1097\/PAS.0000000000000365","article-title":"Expression profiles of MYC protein and MYC gene rearrangement in lymphomas","volume":"39","author":"Chisholm","year":"2015","journal-title":"Am J Surg Pathol"}],"container-title":["The American Journal of the Medical Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002962917303038?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002962917303038?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,8,24]],"date-time":"2023-08-24T01:58:37Z","timestamp":1692842317000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002962917303038"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1]]},"references-count":112,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,1]]}},"alternative-id":["S0002962917303038"],"URL":"https:\/\/doi.org\/10.1016\/j.amjms.2017.06.007","relation":{},"ISSN":["0002-9629"],"issn-type":[{"value":"0002-9629","type":"print"}],"subject":[],"published":{"date-parts":[[2018,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Is Myc an Important Biomarker? Myc Expression in Immune Disorders and Cancer","name":"articletitle","label":"Article Title"},{"value":"The American Journal of the Medical Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.amjms.2017.06.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Southern Society for Clinical Investigation. Published by All rights reserved.","name":"copyright","label":"Copyright"}]}}