{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T07:21:24Z","timestamp":1789888884052,"version":"4.0.1"},"reference-count":9,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T00:00:00Z","timestamp":1559347200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T00:00:00Z","timestamp":1559347200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["amjmedsci.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of the Medical Sciences"],"published-print":{"date-parts":[[2019,6]]},"DOI":"10.1016\/j.amjms.2019.03.005","type":"journal-article","created":{"date-parts":[[2019,3,22]],"date-time":"2019-03-22T11:58:30Z","timestamp":1553255910000},"page":"507-511","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":20,"title":["Recognition and Management of Medication Excipient Reactivity in Patients With Mast Cell Activation Syndrome"],"prefix":"10.1016","volume":"357","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0053-3996","authenticated-orcid":false,"given":"Jill R.","family":"Schofield","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lawrence B.","family":"Afrin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"9","key":"10.1016\/j.amjms.2019.03.005_bib0001","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1080\/00365520701245744","article-title":"Multiple novel alterations in Kit tyrosine kinase in patients with gastrointestinally pronounced systemic mast cell activation disorder","volume":"42","author":"Molderings","year":"2007","journal-title":"Scand J Gastroenterol"},{"issue":"6","key":"10.1016\/j.amjms.2019.03.005_bib0002","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1016\/j.jaci.2010.08.035","article-title":"Mast cell activation syndrome: proposed diagnostic criteria","volume":"126","author":"Akin","year":"2010","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.amjms.2019.03.005_bib0003","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/1756-8722-4-10","article-title":"Mast cell activation disease: a concise practical guide for diagnostic workup and therapeutic options","volume":"4","author":"Molderings","year":"2011","journal-title":"J Hematol Oncol"},{"issue":"9","key":"10.1016\/j.amjms.2019.03.005_bib0004","doi-asserted-by":"crossref","first-page":"e76241","DOI":"10.1371\/journal.pone.0076241","article-title":"Familial occurrence of systemic mast cell activation disease","volume":"8","author":"Molderings","year":"2013","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.amjms.2019.03.005_bib0005","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.amjms.2016.12.013","article-title":"Characterization of mast cell activation syndrome","volume":"353","author":"Afrin","year":"2017","journal-title":"Am J Med Sci"},{"issue":"2","key":"10.1016\/j.amjms.2019.03.005_bib0006","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.critrevonc.2014.09.001","article-title":"The genetic basis of mast cell activation disease \u2013 looking through a glass darkly","volume":"93","author":"Molderings","year":"2015","journal-title":"Crit Rev Oncol Hematol"},{"issue":"6","key":"10.1016\/j.amjms.2019.03.005_bib0007","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1007\/s00251-017-0981-y","article-title":"Mutational profiling in the peripheral blood leukocytes of patients with systemic mast cell activation syndrome using next-generation sequencing","volume":"69","author":"Atmuller","year":"2017","journal-title":"Immunogenetics"},{"issue":"7","key":"10.1016\/j.amjms.2019.03.005_bib0008","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1007\/s00210-016-1247-1","article-title":"Pharmacological treatment options for mast cell activation disease","volume":"389","author":"Molderings","year":"2016","journal-title":"Naunyn Schmiedebergs Arch Pharmacol"},{"issue":"7","key":"10.1016\/j.amjms.2019.03.005_bib0009","doi-asserted-by":"crossref","first-page":"2019","DOI":"10.1016\/j.xphs.2016.03.019","article-title":"An overview of pharmaceutical excipients: safe or not safe?","volume":"105","author":"Abrantes","year":"2016","journal-title":"J Pharm Sci"}],"container-title":["The American Journal of the Medical Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002962919301193?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002962919301193?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T18:36:13Z","timestamp":1757702173000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002962919301193"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6]]},"references-count":9,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2019,6]]}},"alternative-id":["S0002962919301193"],"URL":"https:\/\/doi.org\/10.1016\/j.amjms.2019.03.005","relation":{},"ISSN":["0002-9629"],"issn-type":[{"value":"0002-9629","type":"print"}],"subject":[],"published":{"date-parts":[[2019,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Recognition and Management of Medication Excipient Reactivity in Patients With Mast Cell Activation Syndrome","name":"articletitle","label":"Article Title"},{"value":"The American Journal of the Medical Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.amjms.2019.03.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Southern Society for Clinical Investigation. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}