{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T17:21:45Z","timestamp":1768411305915,"version":"3.49.0"},"reference-count":38,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100012155","name":"National Institute for Medical Research Development","doi-asserted-by":"publisher","award":["963642"],"award-info":[{"award-number":["963642"]}],"id":[{"id":"10.13039\/501100012155","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005756","name":"Shahrekord University of Medical Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005756","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Shahrekord Hajar Hospital"}],"content-domain":{"domain":["amjmedsci.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of the Medical Sciences"],"published-print":{"date-parts":[[2021,1]]},"DOI":"10.1016\/j.amjms.2020.07.030","type":"journal-article","created":{"date-parts":[[2020,7,28]],"date-time":"2020-07-28T13:16:58Z","timestamp":1595942218000},"page":"43-54","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"title":["Up-regulated CCL18, CCL28 and CXCL13 Expression is Associated with the Risk of Gastritis and Peptic Ulcer Disease in Helicobacter Pylori infection"],"prefix":"10.1016","volume":"361","author":[{"given":"Mohammad-Javad","family":"Sanaei","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hedayatollah","family":"Shirzad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amin","family":"Soltani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meghdad","family":"Abdollahpour\u2010Alitappeh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad-Hadi","family":"Shafigh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ghorbanali","family":"Rahimian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yousef","family":"Mirzaei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5196-5513","authenticated-orcid":false,"given":"Nader","family":"Bagheri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.amjms.2020.07.030_bib0001","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1016\/S0140-6736(16)32404-7","article-title":"Peptic ulcer disease","volume":"390","author":"Lanas","year":"2017","journal-title":"Lancet"},{"key":"10.1016\/j.amjms.2020.07.030_bib0002","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1136\/gut.52.2.186","article-title":"Risk factors for peptic ulcer disease: a population based prospective cohort study comprising 2416 Danish adults","volume":"52","author":"Rosenstock","year":"2003","journal-title":"Gut"},{"key":"10.1016\/j.amjms.2020.07.030_bib0003","doi-asserted-by":"crossref","first-page":"5703","DOI":"10.1007\/s11033-019-05004-1","article-title":"Role of Th22 cells in Helicobacter pylori-related gastritis and peptic ulcer diseases","volume":"46","author":"Sanaii","year":"2019","journal-title":"Mol Biol Rep"},{"key":"10.1016\/j.amjms.2020.07.030_bib0004","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1111\/j.1365-2036.2009.03960.x","article-title":"Systematic review: the global incidence and prevalence of peptic ulcer disease","volume":"29","author":"Sung","year":"2009","journal-title":"Aliment Pharmacol Ther"},{"issue":"2","key":"10.1016\/j.amjms.2020.07.030_bib0005","doi-asserted-by":"crossref","first-page":"161","DOI":"10.3109\/08820139.2015.1122615","article-title":"Altered Th17 cytokine expression in Helicobacter pylori patients with TLR4 (D299G) polymorphism","volume":"45","author":"Bagheri","year":"2016","journal-title":"Immunol Invest"},{"key":"10.1016\/j.amjms.2020.07.030_bib0006","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.arcmed.2016.07.013","article-title":"Role of regulatory T-cells in different clinical expressions of Helicobacter pylori Infection","volume":"47","author":"Bagheri","year":"2016","journal-title":"Arch Med Res"},{"key":"10.1016\/j.amjms.2020.07.030_bib0007","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.micpath.2018.06.033","article-title":"The role of T helper 1-cell response in Helicobacter pylori-infection","volume":"123","author":"Bagheri","year":"2018","journal-title":"Microb Pathog"},{"key":"10.1016\/j.amjms.2020.07.030_bib0008","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.micpath.2016.09.016","article-title":"Clinical relevance of Helicobacter pylori virulence factors in Iranian patients with gastrointestinal diseases","volume":"100","author":"Bagheri","year":"2016","journal-title":"Microb Pathog"},{"key":"10.1016\/j.amjms.2020.07.030_bib0009","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1046\/j.1523-5378.1998.08056.x","article-title":"Relationship of vacA genotypes of Helicobacter pylori to cagA status, cytotoxin production, and clinical outcome","volume":"3","author":"Yamaoka","year":"1998","journal-title":"Helicobacter"},{"key":"10.1016\/j.amjms.2020.07.030_bib0010","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.mib.2007.12.003","article-title":"SagA of CagA in Helicobacter pylori pathogenesis","volume":"11","author":"Hatakeyama","year":"2008","journal-title":"Curr Opin Microbiol"},{"key":"10.1016\/j.amjms.2020.07.030_bib0011","doi-asserted-by":"crossref","first-page":"1030","DOI":"10.1053\/j.gastro.2003.12.048","article-title":"Role of interferon-stimulated responsive element-like element in interleukin-8 promoter in Helicobacter pylori infection","volume":"126","author":"Yamaoka","year":"2004","journal-title":"Gastroenterology"},{"key":"10.1016\/j.amjms.2020.07.030_bib0012","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.diagmicrobio.2004.11.007","article-title":"cagA vacA alelles and babA2 genotypes of Helicobacter pylori associated with gastric disease in Brazilian adult patients","volume":"51","author":"Gatti","year":"2005","journal-title":"Diagn Microbiol Infect Dis"},{"key":"10.1016\/j.amjms.2020.07.030_bib0013","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1053\/j.gastro.2007.05.008","article-title":"Immunology of Helicobacter pylori: insights into the failure of the immune response and perspectives on vaccine studies","volume":"133","author":"Wilson","year":"2007","journal-title":"Gastroenterology"},{"key":"10.1016\/j.amjms.2020.07.030_bib0014","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.meegid.2018.02.020","article-title":"Up-regulated Th17 cell function is associated with increased peptic ulcer disease in Helicobacter pylori-infection","volume":"60","author":"Bagheri","year":"2018","journal-title":"Infect Genet Evol"},{"key":"10.1016\/j.amjms.2020.07.030_bib0015","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.micpath.2017.06.040","article-title":"Downregulated regulatory T cell function is associated with increased peptic ulcer in Helicobacter pylori-infection","volume":"110","author":"Bagheri","year":"2017","journal-title":"Microb Pathog"},{"key":"10.1016\/j.amjms.2020.07.030_bib0016","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1038\/84209","article-title":"Chemokines and disease","volume":"2","author":"Gerard","year":"2001","journal-title":"Nat Immunol"},{"key":"10.1016\/j.amjms.2020.07.030_bib0017","doi-asserted-by":"crossref","first-page":"3843","DOI":"10.4049\/jimmunol.170.7.3843","article-title":"Unique regulation of CCL18 production by maturing dendritic cells","volume":"170","author":"Vulcano","year":"2003","journal-title":"J Immunol"},{"key":"10.1016\/j.amjms.2020.07.030_bib0018","doi-asserted-by":"crossref","first-page":"22313","DOI":"10.1074\/jbc.M001461200","article-title":"Identification of a novel chemokine (CCL28), which binds CCR10 (GPR2)","volume":"275","author":"Wang","year":"2000","journal-title":"J Biol Chem"},{"key":"10.1016\/j.amjms.2020.07.030_bib0019","doi-asserted-by":"crossref","first-page":"3304","DOI":"10.1128\/IAI.00041-08","article-title":"CCL28 is increased in human Helicobacter pylori-induced gastritis and mediates recruitment of gastric immunoglobulin A-secreting cells","volume":"76","author":"Hansson","year":"2008","journal-title":"Infect Immun"},{"key":"10.1016\/j.amjms.2020.07.030_bib0020","doi-asserted-by":"crossref","first-page":"1452","DOI":"10.4049\/jimmunol.170.3.1452","article-title":"CCL28 has dual roles in mucosal immunity as a chemokine with broad-spectrum antimicrobial activity","volume":"170","author":"Hieshima","year":"2003","journal-title":"J Immunol"},{"key":"10.1016\/j.amjms.2020.07.030_bib0021","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1189\/jlb.72.1.1","article-title":"Systemic immunoregulatory and pathogenic functions of homeostatic chemokine receptors","volume":"72","author":"M\u00fcller","year":"2002","journal-title":"J Leukoc Biol"},{"key":"10.1016\/j.amjms.2020.07.030_bib0022","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1038\/416094a","article-title":"Balanced responsiveness to chemoattractants from adjacent zones determines B-cell position","volume":"416","author":"Reif","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.amjms.2020.07.030_bib0023","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1097\/00000478-199610000-00001","article-title":"Classification and grading of gastritis: the updated Sydney system","volume":"20","author":"Dixon","year":"1996","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.amjms.2020.07.030_bib0024","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.micpath.2015.01.008","article-title":"Frequency of virulence factors in Helicobacter pylori-infected patients with gastritis","volume":"80","author":"Salimzadeh","year":"2015","journal-title":"Microb Pathog"},{"key":"10.1016\/j.amjms.2020.07.030_bib0025","first-page":"e88231","article-title":"Associations of a NLRP3 rs10754558 polymorphism with Helicobacter pylori-infected patients with gastritis and peptic ulcer disease","volume":"12","author":"Abolfathi","year":"2019","journal-title":"Jundishapur J Microbiol"},{"key":"10.1016\/j.amjms.2020.07.030_bib0026","doi-asserted-by":"crossref","first-page":"2887","DOI":"10.1007\/s10620-011-1717-8","article-title":"Enhanced expression of CXCL13 in human Helicobacter pylori-associated gastritis","volume":"56","author":"Nakashima","year":"2011","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.amjms.2020.07.030_bib0027","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1111\/j.1523-5378.2008.00584.x","article-title":"Helicobacter pylori and antrum erosion\u2010specific gene expression patterns: the discriminative role of CXCL13 and VCAM1 transcripts","volume":"13","author":"Galamb","year":"2008","journal-title":"Helicobacter"},{"key":"10.1016\/j.amjms.2020.07.030_bib0028","doi-asserted-by":"crossref","first-page":"R49","DOI":"10.1172\/JCI7830","article-title":"BCA-1 is highly expressed in Helicobacter pylori\u2013induced mucosa-associated lymphoid tissue and gastric lymphoma","volume":"104","author":"Mazzucchelli","year":"1999","journal-title":"J Clin Invest"},{"key":"10.1016\/j.amjms.2020.07.030_bib0029","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1111\/j.1574-695X.2010.00731.x","article-title":"Helicobacter heilmannii can induce gastric lymphoid follicles in mice via a Peyer's patch-independent pathway","volume":"60","author":"Nobutani","year":"2010","journal-title":"FEMS Immunol Med Microbiol"},{"key":"10.1016\/j.amjms.2020.07.030_bib0030","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1038\/mi.2014.14","article-title":"Anti-CXCL13 antibody can inhibit the formation of gastric lymphoid follicles induced by Helicobacter infection","volume":"7","author":"Yamamoto","year":"2014","journal-title":"Mucosal Immunol"},{"key":"10.1016\/j.amjms.2020.07.030_bib0031","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1038\/mi.2014.66","article-title":"Interferon-\u03b3-producing B cells induce the formation of gastric lymphoid follicles after Helicobacter suis infection","volume":"8","author":"Yang","year":"2015","journal-title":"Mucosal Immunol"},{"key":"10.1016\/j.amjms.2020.07.030_bib0032","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1111\/j.1442-200X.2012.03573.x","article-title":"Microarray analysis of gastric mucosa among children with Helicobacter pylori infection","volume":"54","author":"Ikuse","year":"2012","journal-title":"Pediatr Int"},{"key":"10.1016\/j.amjms.2020.07.030_bib0033","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1038\/nri2448","article-title":"Exploring the full spectrum of macrophage activation","volume":"8","author":"Mosser","year":"2008","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.amjms.2020.07.030_bib0034","doi-asserted-by":"crossref","first-page":"4251","DOI":"10.1128\/IAI.00536-10","article-title":"Sublingual immunization protects against Helicobacter pylori infection and induces T and B cell responses in the stomach","volume":"78","author":"Raghavan","year":"2010","journal-title":"Infect Immun"},{"key":"10.1016\/j.amjms.2020.07.030_bib0035","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1038\/nrc3611","article-title":"Inflammation-induced cancer: crosstalk between tumours, immune cells and microorganisms","volume":"13","author":"Elinav","year":"2013","journal-title":"Nat Rev Cancer"},{"key":"10.1016\/j.amjms.2020.07.030_bib0036","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.arcmed.2019.07.005","article-title":"T-bet(+) Cells polarization in patients infected with Helicobacter pylori increase the risk of peptic ulcer development","volume":"50","author":"Bagheri","year":"2019","journal-title":"Arch Med Res"},{"key":"10.1016\/j.amjms.2020.07.030_bib0037","doi-asserted-by":"crossref","DOI":"10.1016\/j.amjms.2020.03.019","article-title":"Enhanced frequency of CD19(+)IL-10(+)B cells in human gastric mucosa infected by Helicobacter pylori","author":"Nahid-Samiei","year":"2020","journal-title":"Am J Med Sci"},{"key":"10.1016\/j.amjms.2020.07.030_bib0038","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/j.cyto.2016.09.017","article-title":"Chemokine CXCL13 expression was up-regulated in Clostridium difficile infection","volume":"88","author":"Wang","year":"2016","journal-title":"Cytokine"}],"container-title":["The American Journal of the Medical Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002962920303426?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002962920303426?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T18:37:53Z","timestamp":1757702273000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002962920303426"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":38,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["S0002962920303426"],"URL":"https:\/\/doi.org\/10.1016\/j.amjms.2020.07.030","relation":{},"ISSN":["0002-9629"],"issn-type":[{"value":"0002-9629","type":"print"}],"subject":[],"published":{"date-parts":[[2021,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Up-regulated CCL18, CCL28 and CXCL13 Expression is Associated with the Risk of Gastritis and Peptic Ulcer Disease in Helicobacter Pylori infection","name":"articletitle","label":"Article Title"},{"value":"The American Journal of the Medical Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.amjms.2020.07.030","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Southern Society for Clinical Investigation. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}