{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T21:36:46Z","timestamp":1767908206085,"version":"3.49.0"},"reference-count":23,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["amjmedsci.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of the Medical Sciences"],"published-print":{"date-parts":[[2021,9]]},"DOI":"10.1016\/j.amjms.2021.05.010","type":"journal-article","created":{"date-parts":[[2021,5,17]],"date-time":"2021-05-17T11:32:56Z","timestamp":1621251176000},"page":"308-313","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["A Case Report on Type 2 Amiodarone Induced Thyrotoxicosis and Hypercalcemia"],"prefix":"10.1016","volume":"362","author":[{"given":"Kavitha","family":"Ganesan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bobby","family":"Bradley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David W.","family":"Jones","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dr. Solomon","family":"Solomon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"9","key":"10.1016\/j.amjms.2021.05.010_bib0001","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1056\/NEJMct065916","article-title":"Amiodarone for atrial fibrillation","volume":"356","author":"Zimetbaum","year":"2007","journal-title":"N Engl J Med"},{"key":"10.1016\/j.amjms.2021.05.010_bib0002","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1530\/eje.0.1400241","article-title":"Amiodarone compared with iodine exhibits a potent and persistent inhibitory effect on TSH-stimulated cAMP production in vitro: a possible mechanism to explain amiodarone-induced hypothyroidism","volume":"140","author":"Pitsiavas","year":"1999","journal-title":"Eur J Endocrinol"},{"key":"10.1016\/j.amjms.2021.05.010_bib0003","article-title":"Amiodarone-induced thyrotoxicosis","author":"Schubert","year":"2020","journal-title":"Ann Endocrinol"},{"issue":"4","key":"10.1016\/j.amjms.2021.05.010_bib0004","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1111\/j.1365-2265.2007.02920.x","article-title":"Proportion of type 1 and type 2 amiodarone-induced thyrotoxicosis has changed over a 27-year period in Italy","volume":"67","author":"Bogazzi","year":"2007","journal-title":"Clin Endocrinol (Oxf)"},{"key":"10.1016\/j.amjms.2021.05.010_bib0005","unstructured":"IDe Benoist, B. World Health Organization. Iodine status worldwide: WHO global database on iodine deficiency. 2013, October 29."},{"issue":"8","key":"10.1016\/j.amjms.2021.05.010_bib0006","doi-asserted-by":"crossref","first-page":"3474","DOI":"10.1210\/jc.2003-030185","article-title":"Antithyroid drugs in the management of patients with Graves\u2019 disease: an evidence-based approach to therapeutic controversies","volume":"88","author":"Cooper","year":"2003","journal-title":"J Clin Endocrinol Metab"},{"issue":"6332","key":"10.1016\/j.amjms.2021.05.010_bib0007","doi-asserted-by":"crossref","first-page":"1835","DOI":"10.1136\/bmj.284.6332.1835-a","article-title":"Prednisone in amiodarone-induced thyrotoxicosis","volume":"284","author":"Wimpfheimer","year":"1982","journal-title":"Br Med J (Clin Res Ed)"},{"issue":"1","key":"10.1016\/j.amjms.2021.05.010_bib0008","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1210\/clinem\/dgz041","article-title":"Comparison between total thyroidectomy and medical therapy for amiodarone-induced thyrotoxicosis","volume":"105","author":"Cappellani","year":"2020","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.amjms.2021.05.010_bib0009","doi-asserted-by":"crossref","DOI":"10.1253\/circj.CJ-13-0220","article-title":"Amiodarone-induced thyrotoxicosis late after amiodarone withdrawal","author":"Yagishita","year":"2013","journal-title":"Circ J"},{"key":"10.1016\/j.amjms.2021.05.010_bib0010","first-page":"54","article-title":"Issues in amiodarone-induced thyrotoxicosis: update and review of the literature. InAnnales d'endocrinologie","author":"Maqdasy","year":"2019","journal-title":"Elsevier Masson"},{"issue":"2","key":"10.1016\/j.amjms.2021.05.010_bib0011","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/j.emc.2013.12.001","article-title":"Hyperthyroidism and thyrotoxicosis","volume":"32","author":"Devereaux","year":"2014","journal-title":"Emerg Med Clin"},{"issue":"10","key":"10.1016\/j.amjms.2021.05.010_bib0012","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1097\/00007611-199610000-00013","article-title":"Hyperthyroidism manifested as hypercalcemia","volume":"89","author":"Alikhan","year":"1996","journal-title":"South Med J"},{"issue":"4","key":"10.1016\/j.amjms.2021.05.010_bib0013","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000006017","article-title":"Hyperthyroidism-associated hypercalcemic crisis: a case report and review of the literature","volume":"96","author":"Chen","year":"2017","journal-title":"Medicine (Baltimore)"},{"issue":"2","key":"10.1016\/j.amjms.2021.05.010_bib0014","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1016\/j.amjmed.2008.12.017","article-title":"Severe hypercalcemia secondary to factitious thyrotoxicosis","volume":"123","author":"Ashawesh","year":"2010","journal-title":"Am J Med"},{"issue":"6","key":"10.1016\/j.amjms.2021.05.010_bib0015","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1080\/02841850701342138","article-title":"Color-flow Doppler sonography in the differential diagnosis and management of amiodarone-induced thyrotoxicosis","volume":"48","author":"Loy","year":"2007","journal-title":"Acta Radiol"},{"issue":"6","key":"10.1016\/j.amjms.2021.05.010_bib0016","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/j.hlc.2014.01.013","article-title":"An audit of amiodarone-induced thyrotoxicosis-do anti-thyroid drugs alone provide adequate treatment?","volume":"23","author":"Patel","year":"2014","journal-title":"Heart, Lung Circ"},{"issue":"6","key":"10.1016\/j.amjms.2021.05.010_bib0017","doi-asserted-by":"crossref","first-page":"1881","DOI":"10.1210\/jc.2009-0850","article-title":"Putting propylthiouracil in perspective","volume":"94","author":"Cooper","year":"2009","journal-title":"J Clin Endocrinol Metab"},{"issue":"11","key":"10.1016\/j.amjms.2021.05.010_bib0018","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1161\/circ.105.11.1275","article-title":"Successful treatment of amiodarone- induced thyrotoxicosis","volume":"105","author":"Osman","year":"2002","journal-title":"Circulation"},{"issue":"6","key":"10.1016\/j.amjms.2021.05.010_bib0019","first-page":"716","article-title":"Radioactive iodine in the treatment of type-2 amiodarone-induced thyrotoxicosis","volume":"100","author":"Alptekin","year":"2008","journal-title":"J Natl Med Assoc"},{"key":"10.1016\/j.amjms.2021.05.010_bib0020","article-title":"Sudden onset of thyrotoxicosis induced by amiodarone mimicking low cardiac output syndrome in a patient with dilated cardiomyopathy","author":"Iyama","year":"2020","journal-title":"J Cardiol Cases"},{"key":"10.1016\/j.amjms.2021.05.010_bib0021","article-title":"Williams textbook of endocrinology E- book","author":"Melmed","year":"2015","journal-title":"Elsevier Health Sci"},{"issue":"01","key":"10.1016\/j.amjms.2021.05.010_bib0022","first-page":"45","article-title":"Total thyroidectomy for amiodarone-induced thyrotoxicosis in the hyperthyroid state","volume":"124","author":"Kaderli","year":"2016","journal-title":"Exp Clin Endocrinol Diabetes"},{"issue":"60","key":"10.1016\/j.amjms.2021.05.010_bib0023","doi-asserted-by":"crossref","first-page":"e43","DOI":"10.1016\/j.endoen.2013.12.002","article-title":"Management of severe amiodarone-induced thyrotoxicosis after failure of standard medical treatment","volume":"10","author":"Gavira","year":"2013","journal-title":"Endocrinol Nutri (English Edition)"}],"container-title":["The American Journal of the Medical Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002962921001804?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002962921001804?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T18:39:34Z","timestamp":1757702374000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002962921001804"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9]]},"references-count":23,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,9]]}},"alternative-id":["S0002962921001804"],"URL":"https:\/\/doi.org\/10.1016\/j.amjms.2021.05.010","relation":{},"ISSN":["0002-9629"],"issn-type":[{"value":"0002-9629","type":"print"}],"subject":[],"published":{"date-parts":[[2021,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A Case Report on Type 2 Amiodarone Induced Thyrotoxicosis and Hypercalcemia","name":"articletitle","label":"Article Title"},{"value":"The American Journal of the Medical Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.amjms.2021.05.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Southern Society for Clinical Investigation. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}