{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T23:09:57Z","timestamp":1779318597526,"version":"3.51.4"},"reference-count":30,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100000871","name":"Mayo Clinic","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000871","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["amjmedsci.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of the Medical Sciences"],"published-print":{"date-parts":[[2022,2]]},"DOI":"10.1016\/j.amjms.2021.06.018","type":"journal-article","created":{"date-parts":[[2021,8,15]],"date-time":"2021-08-15T09:22:49Z","timestamp":1629019369000},"page":"140-146","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["Native Vertebral Osteomyelitis in Patients with Staphylococcus Aureus Bacteremia"],"prefix":"10.1016","volume":"363","author":[{"given":"Khawaja M.","family":"Talha","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Larry M.","family":"Baddour","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hassan","family":"Ishaq","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rommel","family":"Ramesh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Verda","family":"Arshad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wajeeha","family":"Tariq","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karen M.","family":"Fischer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elie F.","family":"Berbari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. Rizwan","family":"Sohail","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raj","family":"Palraj","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"10","key":"10.1016\/j.amjms.2021.06.018_bib0001","doi-asserted-by":"crossref","first-page":"837","DOI":"10.2106\/JBJS.N.01350","article-title":"Trends in the epidemiology of osteomyelitis: a population-based study, 1969 to 2009","volume":"97","author":"Kremers","year":"2015","journal-title":"Bone Jt Surg Am"},{"issue":"2","key":"10.1016\/j.amjms.2021.06.018_bib0002","doi-asserted-by":"crossref","DOI":"10.1097\/BSD.0000000000000597","article-title":"The epidemiology of vertebral osteomyelitis in the United States from 1998 to 2013","volume":"31","author":"Issa","year":"2018","journal-title":"Clin Spine Surg"},{"issue":"4","key":"10.1016\/j.amjms.2021.06.018_bib0003","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.jinf.2013.11.011","article-title":"Increasing incidence of pyogenic spondylodiscitis: a 14-year population-based study","volume":"68","author":"Kehrer","year":"2014","journal-title":"J Infect"},{"key":"10.1016\/j.amjms.2021.06.018_bib0004","doi-asserted-by":"crossref","unstructured":"Mylona E, Samarkos M, Kakalou E, et al. Pyogenic vertebral osteomyelitis: a systematic review of clinical characteristics. Paper presented at: Seminars in arthritis and rheumatism 2009.","DOI":"10.1016\/j.semarthrit.2008.03.002"},{"issue":"9","key":"10.1016\/j.amjms.2021.06.018_bib0005","first-page":"197","article-title":"Invasive methicillin-resistant Staphylococcus aureus infections among dialysis patients\u2013United States, 2005","volume":"56","year":"2007","journal-title":"MMWR Morb Mortal Wkly Rep"},{"issue":"Supplement_4","key":"10.1016\/j.amjms.2021.06.018_bib0006","doi-asserted-by":"crossref","first-page":"S231","DOI":"10.1086\/598189","article-title":"Staphylococcus aureus bacteremia: epidemiology, pathophysiology, and management strategies","volume":"48","author":"Naber","year":"2009","journal-title":"Clin Infect Dis"},{"issue":"3","key":"10.1016\/j.amjms.2021.06.018_bib0007","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1038\/nrmicro2508","article-title":"Are bloodstream leukocytes Trojan Horses for the metastasis of Staphylococcus aureus?","volume":"9","author":"Thwaites","year":"2011","journal-title":"Na Rev Microbiol"},{"issue":"3","key":"10.1016\/j.amjms.2021.06.018_bib0008","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/j.ccc.2013.03.008","article-title":"Staphylococcus aureus bacteremia, risk factors, complications, and management","volume":"29","author":"Keynan","year":"2013","journal-title":"Crit Care Clin"},{"issue":"17","key":"10.1016\/j.amjms.2021.06.018_bib0009","doi-asserted-by":"crossref","first-page":"2066","DOI":"10.1001\/archinte.163.17.2066","article-title":"Clinical identifiers of complicated Staphylococcus aureus bacteremia","volume":"163","author":"Fowler","year":"2003","journal-title":"Arch Intern Med"},{"issue":"2","key":"10.1016\/j.amjms.2021.06.018_bib0010","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.jinf.2008.04.012","article-title":"Outcomes of treatment for hematogenous Staphylococcus aureus vertebral osteomyelitis in the MRSA ERA","volume":"57","author":"Livorsi","year":"2008","journal-title":"J Infect"},{"key":"10.1016\/j.amjms.2021.06.018_bib0011","article-title":"Hematogenous vertebral osteomyelitis due to Staphylococcus aureus in the adult: clinical features and therapeutic outcomes","volume":"982005","author":"Priest","year":"2021","journal-title":"South Med J"},{"issue":"2","key":"10.1016\/j.amjms.2021.06.018_bib0012","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.jbi.2008.08.010","article-title":"Research electronic data capture (REDCap)\u2014a metadata-driven methodology and workflow process for providing translational research informatics support","volume":"42","author":"Harris","year":"2009","journal-title":"J Biomed Inform"},{"key":"10.1016\/j.amjms.2021.06.018_bib0013","doi-asserted-by":"crossref","DOI":"10.1016\/j.jbi.2019.103208","article-title":"The REDCap consortium: building an international community of software platform partners","volume":"95","author":"Harris","year":"2019","journal-title":"J Biomed Inform"},{"issue":"6","key":"10.1016\/j.amjms.2021.06.018_bib0014","doi-asserted-by":"crossref","first-page":"e26","DOI":"10.1093\/cid\/civ482","article-title":"2015 Infectious Diseases Society of America (IDSA) clinical practice guidelines for the diagnosis and treatment of native vertebral osteomyelitis in adults","volume":"61","author":"Berbari","year":"2015","journal-title":"Clin Infect Dis"},{"issue":"4","key":"10.1016\/j.amjms.2021.06.018_bib0015","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1086\/313753","article-title":"Proposed modifications to the Duke criteria for the diagnosis of infective endocarditis","volume":"30","author":"Li","year":"2000","journal-title":"Clin Infect Dis"},{"issue":"1","key":"10.1016\/j.amjms.2021.06.018_bib0016","doi-asserted-by":"crossref","DOI":"10.1186\/s13054-017-1801-3","article-title":"Incidence, prevalence, and management of MRSA bacteremia across patient populations-a review of recent developments in MRSA management and treatment","volume":"21","author":"Hassoun","year":"2017","journal-title":"Crit Care"},{"issue":"11","key":"10.1016\/j.amjms.2021.06.018_bib0017","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1016\/j.amjmed.2005.02.027","article-title":"Spontaneous pyogenic vertebral osteomyelitis and endocarditis: incidence, risk factors, and outcome","volume":"118","author":"Pigrau","year":"2005","journal-title":"Am J Med"},{"issue":"1","key":"10.1016\/j.amjms.2021.06.018_bib0018","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/cid\/cir320","article-title":"Use of a simple criteria set for guiding echocardiography in nosocomial Staphylococcus aureus bacteremia","volume":"53","author":"Kaasch","year":"2011","journal-title":"Clin Infect Dis"},{"issue":"5","key":"10.1016\/j.amjms.2021.06.018_bib0019","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1016\/j.jinf.2016.02.003","article-title":"The VIRSTA score, a prediction score to estimate risk of infective endocarditis and determine priority for echocardiography in patients with Staphylococcus aureus bacteremia","volume":"72","author":"Tubiana","year":"2016","journal-title":"J Infect"},{"issue":"3","key":"10.1016\/j.amjms.2021.06.018_bib0020","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/j.jinf.2014.03.017","article-title":"Long-term mortality after Staphylococcus aureus spondylodiscitis: a Danish nationwide population-based cohort study","volume":"69","author":"Aagaard","year":"2014","journal-title":"J Infect"},{"issue":"2","key":"10.1016\/j.amjms.2021.06.018_bib0021","doi-asserted-by":"crossref","first-page":"92","DOI":"10.3109\/00952991003592311","article-title":"Risk practices associated with bacterial infections among injection drug users in Denver, Colorado","volume":"36","author":"Phillips","year":"2010","journal-title":"Am J Drug Alcohol Abuse"},{"issue":"3","key":"10.1016\/j.amjms.2021.06.018_bib0022","doi-asserted-by":"crossref","first-page":"446","DOI":"10.3201\/eid2603.191408","article-title":"Methicillin-resistant Staphylococcus aureus bloodstream infections and injection drug use, Tennessee, USA, 2015-2017","volume":"26","author":"Parikh","year":"2020","journal-title":"Emerg Infect Dis"},{"issue":"22","key":"10.1016\/j.amjms.2021.06.018_bib0023","doi-asserted-by":"crossref","first-page":"625","DOI":"10.15585\/mmwr.mm6722a2","article-title":"Invasive methicillin-resistant Staphylococcus aureus infections among persons who inject drugs - six sites, 2005\u20132016","volume":"67","author":"Jackson","year":"2018","journal-title":"MMWR Morb Mortal Wkly Rep"},{"issue":"3","key":"10.1016\/j.amjms.2021.06.018_bib0024","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1007\/s10900-017-0458-9","article-title":"Using population based hospitalization data to monitor increases in conditions causing morbidity among persons who inject drugs","volume":"43","author":"Collier","year":"2018","journal-title":"J Community Health"},{"issue":"1","key":"10.1016\/j.amjms.2021.06.018_bib0025","doi-asserted-by":"crossref","first-page":"10798","DOI":"10.1038\/s41598-019-47258-6","article-title":"Cigarette smoke exposure redirects Staphylococcus aureus to a virulence profile associated with persistent infection","volume":"9","author":"Lacoma","year":"2019","journal-title":"Sci Rep"},{"issue":"1","key":"10.1016\/j.amjms.2021.06.018_bib0026","doi-asserted-by":"crossref","first-page":"268","DOI":"10.18632\/oncotarget.13613","article-title":"Impacts of cigarette smoking on immune responsiveness: up and down or upside down?","volume":"8","author":"Qiu","year":"2017","journal-title":"Oncotarget"},{"issue":"1","key":"10.1016\/j.amjms.2021.06.018_bib0027","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijmm.2020.151471","article-title":"A longitudinal study shows intermittent colonization by Staphylococcus aureus with a high genetic diversity in hemodialysis patients","volume":"311","author":"Vanegas","year":"2021","journal-title":"Int J Med Microbiol"},{"issue":"9","key":"10.1016\/j.amjms.2021.06.018_bib0028","doi-asserted-by":"crossref","first-page":"2131","DOI":"10.1681\/ASN.2013091028","article-title":"Meta-analysis of methicillin-resistant Staphylococcus aureus colonization and risk of infection in dialysis patients","volume":"25","author":"Zacharioudakis","year":"2014","journal-title":"J Am Soc Nephrol"},{"issue":"3","key":"10.1016\/j.amjms.2021.06.018_bib0029","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1080\/21505594.2016.1141162","article-title":"Bloodstream infections in patients with liver cirrhosis","volume":"7","author":"Bartoletti","year":"2016","journal-title":"Virulence"},{"issue":"6","key":"10.1016\/j.amjms.2021.06.018_bib0030","doi-asserted-by":"crossref","first-page":"703","DOI":"10.14444\/5088","article-title":"Vertebral osteomyelitis: a comparison of associated outcomes in early versus delayed surgical treatment","volume":"12","author":"Segreto","year":"2018","journal-title":"Int J Spine Surg"}],"container-title":["The American Journal of the Medical Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002962921002810?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002962921002810?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T18:40:42Z","timestamp":1757702442000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002962921002810"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2]]},"references-count":30,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,2]]}},"alternative-id":["S0002962921002810"],"URL":"https:\/\/doi.org\/10.1016\/j.amjms.2021.06.018","relation":{},"ISSN":["0002-9629"],"issn-type":[{"value":"0002-9629","type":"print"}],"subject":[],"published":{"date-parts":[[2022,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Native Vertebral Osteomyelitis in Patients with Staphylococcus Aureus Bacteremia","name":"articletitle","label":"Article Title"},{"value":"The American Journal of the Medical Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.amjms.2021.06.018","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Southern Society for Clinical Investigation. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}