{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T18:13:20Z","timestamp":1783707200434,"version":"3.55.0"},"reference-count":37,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100003347","name":"Fudan University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003347","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["amjmedsci.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of the Medical Sciences"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.amjms.2026.06.008","type":"journal-article","created":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T15:37:58Z","timestamp":1781019478000},"page":"139-145","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Association of better cardiovascular health defined by life\u2019s essential 8 with lower incidences of lung diseases"],"prefix":"10.1016","volume":"372","author":[{"given":"Yi-Zhe","family":"Bian","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Su","family":"Zou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Lyu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying-Jia","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gao-Feng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi-Qing","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.amjms.2026.06.008_bib0001","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1016\/j.hrtlng.2024.09.002","article-title":"Cardiometabolic Index and chronic obstructive pulmonary disease: a population-based cross-sectional study","volume":"68","author":"Wang","year":"2024","journal-title":"Heart Lung"},{"issue":"6","key":"10.1016\/j.amjms.2026.06.008_bib0002","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1016\/j.amjms.2024.07.023","article-title":"COPD overlap conditions: clinical and therapeutic implications","volume":"368","author":"Jarrah","year":"2024","journal-title":"Am J Med Sci"},{"issue":"6","key":"10.1016\/j.amjms.2026.06.008_bib0003","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/j.amjms.2024.03.014","article-title":"The clinical and hemodynamic characteristics of pulmonary hypertension in patients with OSA-COPD overlap syndrome","volume":"367","author":"Hu","year":"2024","journal-title":"Am J Med Sci"},{"issue":"2","key":"10.1016\/j.amjms.2026.06.008_bib0004","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.amjms.2023.11.006","article-title":"Echocardiography and pulmonary hypertension in patients with chronic obstructive pulmonary disease undergoing lung transplantation evaluation","volume":"367","author":"Younis","year":"2024","journal-title":"Am J Med Sci"},{"issue":"11","key":"10.1016\/j.amjms.2026.06.008_bib0005","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1164\/rccm.201604-0690SO","article-title":"Chronic obstructive pulmonary disease and cardiac diseases. An urgent need for integrated care","volume":"194","author":"Roversi","year":"2016","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.amjms.2026.06.008_bib0006","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.hrtlng.2025.06.004","article-title":"The interplay between symptom deterioration of chronic obstructive pulmonary disease and chronic heart failure","volume":"74","author":"van Dijk","year":"2025","journal-title":"Heart Lung"},{"key":"10.1016\/j.amjms.2026.06.008_bib0007","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.hrtlng.2025.04.024","article-title":"Association between patent foramen ovale and chronic obstructive pulmonary disease: a systematic review and meta-analysis","volume":"73","author":"Balakumar","year":"2025","journal-title":"Heart Lung"},{"issue":"4","key":"10.1016\/j.amjms.2026.06.008_bib0008","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1016\/j.amjms.2024.11.002","article-title":"Cardiovascular diseases-related mortality among adults with comorbid chronic obstructive pulmonary disease in the United States","volume":"369","author":"Qamar","year":"2025","journal-title":"Am J Med Sci"},{"issue":"1","key":"10.1016\/j.amjms.2026.06.008_bib0009","first-page":"55","article-title":"Physical activity and the risk of chronic obstructive pulmonary disease: a longitudinal follow-up study in Taiwan","volume":"368","author":"Lee","year":"2024","journal-title":"Am J Med Sci"},{"issue":"4","key":"10.1016\/j.amjms.2026.06.008_bib0010","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/j.amjms.2025.07.001","article-title":"COPET study findings regarding the clinical relevance of biomass exposure as an etiotype in COPD","volume":"370","author":"Yazar","year":"2025","journal-title":"Am J Med Sci"},{"issue":"4","key":"10.1016\/j.amjms.2026.06.008_bib0011","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/j.amjms.2025.07.010","article-title":"Exploring the obesity parADOX: a multisystem review","volume":"370","author":"Aggrawa l","year":"2025","journal-title":"Am J Med Sci"},{"issue":"5","key":"10.1016\/j.amjms.2026.06.008_bib0012","doi-asserted-by":"crossref","first-page":"e18","DOI":"10.1161\/CIR.0000000000001078","article-title":"Life\u2019s essential 8: updating and enhancing the American heart association\u2019s construct of cardiovascular health: a presidential advisory from the American heart association","volume":"146","author":"Lloyd-Jones","year":"2022","journal-title":"Circulation"},{"issue":"1","key":"10.1016\/j.amjms.2026.06.008_bib0013","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.amjms.2024.08.021","article-title":"Association between cardiovascular health and serum vitamin D and its interaction with prediabetes and diabetes","volume":"369","author":"Chen","year":"2025","journal-title":"Am J Med Sci"},{"issue":"5","key":"10.1016\/j.amjms.2026.06.008_bib0014","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/j.amjms.2025.08.008","article-title":"Cardiovascular health and gender minority stress in transgender and gender diverse adults: a cross-sectional study","volume":"370","author":"Sowmiyanarayanan","year":"2025","journal-title":"Am J Med Sci"},{"issue":"4","key":"10.1016\/j.amjms.2026.06.008_bib0015","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1161\/CIRCULATIONAHA.109.192703","article-title":"Defining and setting national goals for cardiovascular health promotion and disease reduction: the American heart association\u2019s strategic impact goal through 2020 and beyond","volume":"121","author":"Lloyd-Jones","year":"2010","journal-title":"Circulation"},{"key":"10.1016\/j.amjms.2026.06.008_bib0016","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.rmed.2017.08.001","article-title":"Association of lung function and chronic obstructive pulmonary disease with American heart association\u2019s life\u2019s Simple 7 cardiovascular health metrics","volume":"131","author":"Fan","year":"2017","journal-title":"Respir Med"},{"issue":"3","key":"10.1016\/j.amjms.2026.06.008_bib0017","doi-asserted-by":"crossref","first-page":"179","DOI":"10.7326\/0003-4819-155-3-201108020-00008","article-title":"Diagnosis and management of stable chronic obstructive pulmonary disease: a clinical practice guideline update from the American college of physicians, American college of chest physicians, American thoracic society, and European respiratory society","volume":"155","author":"Qaseem","year":"2011","journal-title":"Ann Intern Med"},{"issue":"3","key":"10.1016\/j.amjms.2026.06.008_bib0018","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/j.ccm.2014.06.001","article-title":"Sleep and breathing","volume":"35","author":"Newton","year":"2014","journal-title":"Clin Chest Med."},{"issue":"2","key":"10.1016\/j.amjms.2026.06.008_bib0019","first-page":"236","article-title":"Chronic obstructive pulmonary disease and obstructive sleep apnoea-the overlap syndrome","volume":"8","author":"McNicholas","year":"2016","journal-title":"J Thorac Dis"},{"issue":"153","key":"10.1016\/j.amjms.2026.06.008_bib0020","doi-asserted-by":"crossref","DOI":"10.1183\/16000617.0064-2019","article-title":"Sleep in chronic respiratory disease: COPD and hypoventilation disorders","volume":"28","author":"McNicholas","year":"2019","journal-title":"Eur Respir Rev"},{"issue":"2","key":"10.1016\/j.amjms.2026.06.008_bib0021","doi-asserted-by":"crossref","first-page":"167","DOI":"10.7326\/M20-1340","article-title":"Peripheral neuropathy and all-cause and cardiovascular mortality in U.S. Adults: a prospective cohort study","volume":"174","author":"Hicks","year":"2021","journal-title":"Ann Intern Med"},{"issue":"9","key":"10.1016\/j.amjms.2026.06.008_bib0022","doi-asserted-by":"crossref","first-page":"417","DOI":"10.5694\/mja2.50120","article-title":"Coexisting chronic obstructive pulmonary disease and cardiovascular disease in clinical practice: a diagnostic and therapeutic challenge","volume":"210","author":"Leong","year":"2019","journal-title":"Med J Aust"},{"issue":"2","key":"10.1016\/j.amjms.2026.06.008_bib0023","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.tcm.2019.12.009","article-title":"Lung function and cardiovascular disease: a link","volume":"31","author":"Ramalho","year":"2021","journal-title":"Trends Cardiovasc Med"},{"issue":"3","key":"10.1016\/j.amjms.2026.06.008_bib0024","doi-asserted-by":"crossref","first-page":"285","DOI":"10.2174\/18756212MTA1hMzMj4","article-title":"Cardiovascular disease in patients with chronic obstructive pulmonary disease, obstructive sleep apnoea syndrome and overlap syndrome","volume":"19","author":"Voulgaris","year":"2021","journal-title":"Curr Vasc Pharmacol"},{"issue":"8","key":"10.1016\/j.amjms.2026.06.008_bib0025","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1016\/S2213-2600(15)00241-6","article-title":"Risk of cardiovascular comorbidity in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis","volume":"3","author":"Chen","year":"2015","journal-title":"Lancet Respir Med"},{"key":"10.1016\/j.amjms.2026.06.008_bib0026","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/j.sleep.2023.10.034","article-title":"Prevalence and clinical characteristics of sleep disorders in chronic obstructive pulmonary disease: a systematic review and meta-analysis","volume":"112","author":"Du","year":"2023","journal-title":"Sleep Med"},{"issue":"13","key":"10.1016\/j.amjms.2026.06.008_bib0027","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1097\/CM9.0000000000002830","article-title":"Life\u2019s Essential 8 and risk of non-communicable chronic diseases: outcome-wide analyses","volume":"137","author":"Yu","year":"2024","journal-title":"Chin Med J (Engl)"},{"issue":"2","key":"10.1016\/j.amjms.2026.06.008_bib0028","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1097\/MCP.0000000000001040","article-title":"Chronic obstructive pulmonary disease and cardiovascular disease: mechanistic links and implications for practice","volume":"30","author":"Maeda","year":"2024","journal-title":"Curr Opin Pulm Med"},{"issue":"7","key":"10.1016\/j.amjms.2026.06.008_bib0029","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1136\/thx.2003.019588","article-title":"Association between chronic obstructive pulmonary disease and systemic inflammation: a systematic review and a meta-analysis","volume":"59","author":"Gan","year":"2004","journal-title":"Thorax"},{"issue":"5","key":"10.1016\/j.amjms.2026.06.008_bib0030","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0037483","article-title":"Persistent systemic inflammation is associated with poor clinical outcomes in COPD: a novel phenotype","volume":"7","author":"Agust\u00ed","year":"2012","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.amjms.2026.06.008_bib0031","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.jaci.2016.05.011","article-title":"Inflammatory mechanisms in patients with chronic obstructive pulmonary disease","volume":"138","author":"Barnes","year":"2016","journal-title":"J Allergy Clin Immunol"},{"issue":"5","key":"10.1016\/j.amjms.2026.06.008_bib0032","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1164\/rccm.200607-896OC","article-title":"Regular physical activity modifies smoking-related lung function decline and reduces risk of chronic obstructive pulmonary disease: a population-based cohort study","volume":"175","author":"Garcia-Aymerich","year":"2007","journal-title":"Am J Respir Crit Care Med"},{"issue":"6","key":"10.1016\/j.amjms.2026.06.008_bib0033","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1164\/rccm.200807-1195OC","article-title":"Lung function impairment and metabolic syndrome: the critical role of abdominal obesity","volume":"179","author":"Leone","year":"2009","journal-title":"Am J Respir Crit Care Med"},{"issue":"2 Suppl","key":"10.1016\/j.amjms.2026.06.008_bib0034","doi-asserted-by":"crossref","first-page":"637S","DOI":"10.1093\/ajcn\/72.2.637S","article-title":"Antioxidants: what role do they play in physical activity and health?","volume":"72","author":"Clarkson","year":"2000","journal-title":"Am J Clin Nutr"},{"issue":"6","key":"10.1016\/j.amjms.2026.06.008_bib0035","doi-asserted-by":"crossref","first-page":"1647","DOI":"10.2337\/dc07-9921","volume":"30","author":"Klein","year":"2007","journal-title":"Diabetes Care"},{"issue":"1","key":"10.1016\/j.amjms.2026.06.008_bib0036","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1038\/s41392-023-01496-3","article-title":"Pathophysiological mechanisms and therapeutic approaches in obstructive sleep apnea syndrome","volume":"8","author":"Lv","year":"2023","journal-title":"Signal Transduct Target Ther"},{"issue":"11","key":"10.1016\/j.amjms.2026.06.008_bib0037","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1016\/S2213-2600(16)00097-7","article-title":"Management of chronic obstructive pulmonary disease beyond the lungs","volume":"4","author":"Vanfleteren","year":"2016","journal-title":"Lancet Respir Med"}],"container-title":["The American Journal of the Medical Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002962926002259?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002962926002259?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T17:16:54Z","timestamp":1783703814000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002962926002259"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":37,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["S0002962926002259"],"URL":"https:\/\/doi.org\/10.1016\/j.amjms.2026.06.008","relation":{},"ISSN":["0002-9629"],"issn-type":[{"value":"0002-9629","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Association of better cardiovascular health defined by life\u2019s essential 8 with lower incidences of lung diseases","name":"articletitle","label":"Article Title"},{"value":"The American Journal of the Medical Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.amjms.2026.06.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Southern Society for Clinical Investigation. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}