{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T12:10:51Z","timestamp":1763035851250},"reference-count":34,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2004,3,1]],"date-time":"2004-03-01T00:00:00Z","timestamp":1078099200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American Journal of Otolaryngology"],"published-print":{"date-parts":[[2004,3]]},"DOI":"10.1016\/j.amjoto.2003.11.004","type":"journal-article","created":{"date-parts":[[2004,2,19]],"date-time":"2004-02-19T19:09:42Z","timestamp":1077217782000},"page":"88-93","source":"Crossref","is-referenced-by-count":31,"title":["Total laryngectomy and postoperative radiotherapy for T4 laryngeal cancer: a 14-year review"],"prefix":"10.1016","volume":"25","author":[{"given":"Federico L","family":"Ampil","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cherie Ann O","family":"Nathan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gloria","family":"Caldito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timothy F","family":"Lian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert F","family":"Aarstad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.Murty","family":"Krishnamsetty","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.amjoto.2003.11.004_BIB1","doi-asserted-by":"crossref","first-page":"5","DOI":"10.3322\/canjclin.53.1.5","article-title":"Cancer Statistics, 2003","volume":"53","author":"Jemal","year":"2003","journal-title":"CA A Cancer J Clin"},{"key":"10.1016\/j.amjoto.2003.11.004_BIB2","series-title":"American Joint Committee on Cancer Staging Manual","first-page":"47","article-title":"Larynx","author":"Greene","year":"2002"},{"key":"10.1016\/j.amjoto.2003.11.004_BIB3","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/0278-2391(88)90146-2","article-title":"Adjuvant postoperative external beam radiotherapy in head and neck cancer","volume":"46","author":"Ampil","year":"1988","journal-title":"J Oral Maxillofac Surg"},{"key":"10.1016\/j.amjoto.2003.11.004_BIB4","series-title":"Radiation Oncology, Rationale, Technique, Results","first-page":"3","article-title":"Physical and biological basis of radiation therapy","author":"Hall","year":"2003"},{"key":"10.1016\/j.amjoto.2003.11.004_BIB5","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1001\/archotol.1987.01860070076020","article-title":"Frequency and sites of distant metastases in head and neck squamous cell carcinoma","volume":"113","author":"Zbaren","year":"1987","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.amjoto.2003.11.004_BIB6","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1288\/00005537-198403000-00004","article-title":"Preoperative CT scan evaluation for laryngeal carcinoma","volume":"94","author":"Hoover","year":"1984","journal-title":"Laryngoscope"},{"key":"10.1016\/j.amjoto.2003.11.004_BIB7","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1148\/radiology.151.3.6718729","article-title":"Carcinoma of the larynx and hypopharynx","volume":"151","author":"Silverman","year":"1984","journal-title":"Radiology"},{"key":"10.1016\/j.amjoto.2003.11.004_BIB8","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1002\/hed.2890040304","article-title":"Framework invasion by laryngeal carcinomas","volume":"4","author":"Pittam","year":"1982","journal-title":"Head Neck Surg"},{"key":"10.1016\/j.amjoto.2003.11.004_BIB9","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1002\/(SICI)1097-0142(19960401)77:7<1263::AID-CNCR6>3.0.CO;2-J","article-title":"Pretherapeutic staging of laryngeal carcinoma. Clinical findings, computed tomography, and magnetic resonance imaging compared with histopathology","volume":"77","author":"Zbaren","year":"1996","journal-title":"Cancer"},{"key":"10.1016\/j.amjoto.2003.11.004_BIB10","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1016\/S0030-6665(02)00037-3","article-title":"Imaging in laryngeal cancer","volume":"35","author":"Zinreich","year":"2002","journal-title":"Otolaryngol Clin North Am"},{"key":"10.1016\/j.amjoto.2003.11.004_BIB11","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1017\/S0022215100103202","article-title":"Advanced laryngeal cancer","volume":"101","author":"Meredith","year":"1987","journal-title":"J Laryngol Otol"},{"key":"10.1016\/j.amjoto.2003.11.004_BIB12","doi-asserted-by":"crossref","first-page":"1624","DOI":"10.1288\/00005537-197510000-00002","article-title":"The anterior commissure in glottic carcinoma","volume":"85","author":"Sessions","year":"1975","journal-title":"Laryngoscope"},{"key":"10.1016\/j.amjoto.2003.11.004_BIB13","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1288\/00005537-197509000-00006","article-title":"Carcinoma of the laryngeal glottis therapy and end results","volume":"85","author":"Skolnik","year":"1975","journal-title":"Laryngoscope"},{"key":"10.1016\/j.amjoto.2003.11.004_BIB14","doi-asserted-by":"crossref","first-page":"1424","DOI":"10.1288\/00005537-197509000-00002","article-title":"The evaluation of treatment of patients with extensive squamous cancer of the vocal cords","volume":"85","author":"Jesse","year":"1975","journal-title":"Laryngoscope"},{"key":"10.1016\/j.amjoto.2003.11.004_BIB15","doi-asserted-by":"crossref","first-page":"1625","DOI":"10.1016\/0360-3016(87)90157-X","article-title":"Radiation therapy for advanced (T3T4 N0-N3M0) laryngeal carcinoma: The need for a change of strategy. A radiotherapeutic viewpoint","volume":"13","author":"Karim","year":"1987","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.amjoto.2003.11.004_BIB16","doi-asserted-by":"crossref","first-page":"1522","DOI":"10.1288\/00005537-197509000-00015","article-title":"Analysis of surgical therapy for epidermoid carcinoma of the laryngeal glottis","volume":"85","author":"Ogura","year":"1975","journal-title":"Laryngoscope"},{"key":"10.1016\/j.amjoto.2003.11.004_BIB17","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1001\/archotol.1993.01880210038006","article-title":"Clinical underestimation of laryngeal cancer. Predictive indicators","volume":"119","author":"Nakayama","year":"1993","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.amjoto.2003.11.004_BIB18","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1177\/000348948909800204","article-title":"Laser surgery for vocal cord carcinoma involving the anterior commissure","volume":"98","author":"Krespi","year":"1989","journal-title":"Ann Otol Rhinol Laryngol"},{"key":"10.1016\/j.amjoto.2003.11.004_BIB19","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1046\/j.1445-2197.2003.02562.x","article-title":"Clinical outcome following total laryngectomy for cancer","volume":"73","author":"Hall","year":"2003","journal-title":"AN Z J Surg"},{"key":"10.1016\/j.amjoto.2003.11.004_BIB20","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/0360-3016(89)90006-0","article-title":"Postoperative irradiation for squamous cell carcinoma of the head and neck","volume":"16","author":"Amdur","year":"1989","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.amjoto.2003.11.004_BIB21","doi-asserted-by":"crossref","first-page":"1685","DOI":"10.1056\/NEJM199106133242402","article-title":"Induction chemotherapy plus radiation compared with surgery plus radiation in patients with advanced laryngeal cancer","volume":"324","year":"1991","journal-title":"New Engl J Med"},{"key":"10.1016\/j.amjoto.2003.11.004_BIB22","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1001\/archotol.1973.00780020117011","article-title":"Radiation necrosis of the larynx. Etiology and management","volume":"98","author":"Stell","year":"1973","journal-title":"Arch Otolaryngol"},{"key":"10.1016\/j.amjoto.2003.11.004_BIB23","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1148\/radiology.174.3.2305047","article-title":"MR findings of cartilage invasion by laryngeal cancer","volume":"174","author":"Castelijns","year":"1990","journal-title":"Radiology"},{"key":"10.1016\/j.amjoto.2003.11.004_BIB24","doi-asserted-by":"crossref","first-page":"1507","DOI":"10.1016\/0360-3016(81)90079-1","article-title":"T4N0M0 glottic cancer","volume":"7","author":"Harwood","year":"1981","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.amjoto.2003.11.004_BIB25","first-page":"350","article-title":"Primary radiotherapy with surgery in reserve for advanced laryngeal carcinoma. Results and complications","volume":"15","author":"Croll","year":"1989","journal-title":"Eur J Surg Oncol"},{"key":"10.1016\/j.amjoto.2003.11.004_BIB26","first-page":"444","article-title":"Is organ preservation appropriate for T4 larynx cancer?","volume":"20","author":"Adelstein","year":"1998","journal-title":"Head Neck"},{"key":"10.1016\/j.amjoto.2003.11.004_BIB27","doi-asserted-by":"crossref","first-page":"1451","DOI":"10.1001\/archotol.127.12.1451","article-title":"Bone or cartilage invasion by advanced head and neck cancer. Intra-arterial supradose cisplatin chemotherapy and concomitant radiotherapy for organ preservation","volume":"127","author":"Samant","year":"2001","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.amjoto.2003.11.004_BIB28","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/0002-9610(84)90371-4","article-title":"Management of stage T3 and T4 glottic carcinomas","volume":"148","author":"Yuen","year":"1984","journal-title":"Am J Surg"},{"key":"10.1016\/j.amjoto.2003.11.004_BIB29","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1002\/(SICI)1097-0347(199805)20:3<189::AID-HED1>3.0.CO;2-X","article-title":"Implications of cartilage invasion in surgically treated laryngeal carcinoma","volume":"20","author":"Fagan","year":"1998","journal-title":"Head Neck"},{"key":"10.1016\/j.amjoto.2003.11.004_BIB30","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/0360-3016(85)90180-4","article-title":"Combined surgery and postoperative radiation therapy for advanced laryngeal and hypopharyngeal carcinomas","volume":"11","author":"Mirmanoff","year":"1985","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.amjoto.2003.11.004_BIB31","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/0167-8140(94)90410-3","article-title":"Controversies in the management of laryngeal cancer","volume":"31","author":"O\u2019Sullivan","year":"1994","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.amjoto.2003.11.004_BIB32","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1016\/S0002-9610(99)80324-9","article-title":"Elective neck dissection in the treatment of T3T4N0 squamous cell carcinoma of the larynx","volume":"170","author":"Kligerman","year":"1995","journal-title":"Am J Surg"},{"key":"10.1016\/j.amjoto.2003.11.004_BIB33","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1177\/030089168907500113","article-title":"Postoperative radiotherapy in locally advanced head and neck cancer","volume":"75","author":"Franchin","year":"1989","journal-title":"Tumori"},{"key":"10.1016\/j.amjoto.2003.11.004_BIB34","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1002\/hed.2890100105","article-title":"Combined radiation therapy and surgery in the management of advanced head and neck cancer. Final report of study 73\u201303 of the Radiation Therapy Oncology Group","volume":"10","author":"Kramer","year":"1987","journal-title":"Head Neck Surg"}],"container-title":["American Journal of Otolaryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0196070903001595?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0196070903001595?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,2,15]],"date-time":"2019-02-15T02:25:42Z","timestamp":1550197542000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0196070903001595"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,3]]},"references-count":34,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2004,3]]}},"alternative-id":["S0196070903001595"],"URL":"https:\/\/doi.org\/10.1016\/j.amjoto.2003.11.004","relation":{},"ISSN":["0196-0709"],"issn-type":[{"value":"0196-0709","type":"print"}],"subject":[],"published":{"date-parts":[[2004,3]]}}}