{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T15:38:47Z","timestamp":1760888327422,"version":"build-2065373602"},"reference-count":21,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2009,11,1]],"date-time":"2009-11-01T00:00:00Z","timestamp":1257033600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2009,11,1]],"date-time":"2009-11-01T00:00:00Z","timestamp":1257033600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Otolaryngology"],"published-print":{"date-parts":[[2009,11]]},"DOI":"10.1016\/j.amjoto.2008.07.014","type":"journal-article","created":{"date-parts":[[2009,3,10]],"date-time":"2009-03-10T05:07:36Z","timestamp":1236661656000},"page":"390-395","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":29,"title":["Clinical experiences with bisphosphonate-associated osteonecrosis of the jaws: analysis of 21 cases"],"prefix":"10.1016","volume":"30","author":[{"given":"Luis","family":"Junquera","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lorena","family":"Gallego","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paz","family":"Cuesta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alejandro","family":"Pelaz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan Carlos","family":"de Vicente","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.amjoto.2008.07.014_bib1","first-page":"109","article-title":"Bone necrosis of the jaws associated with bisphosphonate treatment: a report of twenty-nine cases","volume":"77","author":"Merigo","year":"2006","journal-title":"Acta Biomed"},{"key":"10.1016\/j.amjoto.2008.07.014_bib2","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.tripleo.2006.12.004","article-title":"Bisphosphonates and osteonecrosis of the jaws: science and rationale","volume":"104","author":"Gutta","year":"2007","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"10.1016\/j.amjoto.2008.07.014_bib3","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.tripleo.2005.10.045","article-title":"Bisphosphonate-associated osteonecrosis of the jaws. Report of a case and literature review","volume":"102","author":"Leite","year":"2006","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"10.1016\/j.amjoto.2008.07.014_bib4","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/j.tripleo.2006.06.004","article-title":"Bisphosphonate-related osteonecrosis of the jaw: background and guidelines for diagnosis, staging and management","volume":"102","author":"Ruggiero","year":"2006","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"10.1016\/j.amjoto.2008.07.014_bib5","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1111\/j.1600-0714.2004.00269.x","article-title":"Avascular jaw osteonecrosis in association with cancer chemotherapy: series of 10 cases","volume":"34","author":"Bagan","year":"2005","journal-title":"J Oral Pathol Med"},{"key":"10.1016\/j.amjoto.2008.07.014_bib6","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1016\/S0278-2391(03)00720-1","article-title":"Pamidronate (Aredia) and zoledronate (Zometa) induced avascular necrosis of the jaws: a growing epidemic","volume":"61","author":"Marx","year":"2003","journal-title":"J Oral Maxillofac Surg"},{"key":"10.1016\/j.amjoto.2008.07.014_bib7","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/j.joms.2006.11.003","article-title":"American Association of Oral and Maxillofacial Surgeons position paper on bisphosphonate-related osteonecrosis of the jaws","volume":"65","author":"Advisory Task Force on Bisphosphonate-Related Osteonecrosis of the Jaws","year":"2007","journal-title":"J Oral Maxillofac Surg"},{"key":"10.1016\/j.amjoto.2008.07.014_bib8","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/j.joms.2006.10.061","article-title":"Nature and frequency of bisphosphonate-associated osteonecrosis of the jaws in Australia","volume":"65","author":"Mavrokokki","year":"2007","journal-title":"J Oral Maxillofac"},{"key":"10.1016\/j.amjoto.2008.07.014_bib9","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1056\/NEJM200507073530120","article-title":"Osteonecrosis of the jaw and bisphosphonates","volume":"353","author":"Durie","year":"2005","journal-title":"N Engl J Med"},{"key":"10.1016\/j.amjoto.2008.07.014_bib10","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/j.joms.2004.02.004","article-title":"Osteonecrosis of the jaws associated with the use of bisphosphonates: a review of 63 cases","volume":"62","author":"Ruggiero","year":"2004","journal-title":"J Oral Maxillofac Surg"},{"key":"10.1016\/j.amjoto.2008.07.014_bib11","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.1016\/j.joms.2005.07.010","article-title":"Bisphosphonate-induced exposed bone (osteonecrosis\/osteopetrosis) of the jaws: risk factors, recognition, prevention, and treatment","volume":"63","author":"Marx","year":"2005","journal-title":"J Oral Maxillofac Surg"},{"key":"10.1016\/j.amjoto.2008.07.014_bib12","doi-asserted-by":"crossref","first-page":"1799","DOI":"10.1056\/NEJMoa074941","article-title":"Zoledronic acid and clinical fractures and mortality after hip fracture","volume":"357","author":"Lyles","year":"2007","journal-title":"N Engl J Med"},{"key":"10.1016\/j.amjoto.2008.07.014_bib13","first-page":"146","article-title":"Osteonecrosis in the jaws of patients who are using oral bisphosphonates to treat osteoporosis","volume":"22","author":"Dello Russo","year":"2007","journal-title":"Int J Oral Maxillofac Implants"},{"key":"10.1016\/j.amjoto.2008.07.014_bib14","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1177\/08959374990130012301","article-title":"In vivo bone response to biochemical loading at the bone\/dental-implant interface","volume":"13","author":"Brunski","year":"1999","journal-title":"Adv Dent Res"},{"key":"10.1016\/j.amjoto.2008.07.014_bib15","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1093\/annonc\/mdl294","article-title":"Bisphosphonates and osteonecrosis of the jaw: cause and effect or a post hoc fallacy","volume":"17","author":"Van den Wyngaert","year":"2006","journal-title":"Ann Oncol"},{"key":"10.1016\/j.amjoto.2008.07.014_bib16","doi-asserted-by":"crossref","first-page":"753","DOI":"10.7326\/0003-4819-144-10-200605160-00009","article-title":"Systematic review: bisphosphonates and osteonecrosis of the jaws","volume":"144","author":"Woo","year":"2006","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.amjoto.2008.07.014_bib17","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.amjoto.2006.08.004","article-title":"Osteonecrosis of the jaws due to bisphosphonate use. A review of 60 cases and treatment proposals","volume":"28","author":"Magopoulos","year":"2007","journal-title":"Am J Otolaryngol"},{"key":"10.1016\/j.amjoto.2008.07.014_bib18","doi-asserted-by":"crossref","first-page":"2397","DOI":"10.1016\/j.joms.2007.08.003","article-title":"Oral bisphosphonate-induced osteonecrosis: risk factors, prediction of risk using serum CTX testing, prevention, and treatment","volume":"65","author":"Marx","year":"2007","journal-title":"J Oral Maxillofac Surg"},{"key":"10.1016\/j.amjoto.2008.07.014_bib19","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1200\/JCO.2005.04.2465","article-title":"Osteonecrosis of the jaw in multiple myeloma patients: clinical features and risk factors","volume":"24","author":"Badros","year":"2006","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.amjoto.2008.07.014_bib20","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1007\/PL00005830","article-title":"Serum CTX: a new marker of bone resorption that shows treatment effect more often than other markers because of low coefficient of variability and large changes with bisphosphonate therapy","volume":"66","author":"Rosen","year":"2000","journal-title":"Calcif Tissue Int"},{"key":"10.1016\/j.amjoto.2008.07.014_bib21","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1007\/s00198-004-1712-4","article-title":"Serum levels of C-terminal telopeptide of type I collagen: a useful new marker of cortical bone loss in hemodialysis patients","volume":"16","author":"Okuno","year":"2005","journal-title":"Osteoporos Int"}],"container-title":["American Journal of Otolaryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0196070908001464?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0196070908001464?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T04:55:12Z","timestamp":1759294512000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0196070908001464"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,11]]},"references-count":21,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2009,11]]}},"alternative-id":["S0196070908001464"],"URL":"https:\/\/doi.org\/10.1016\/j.amjoto.2008.07.014","relation":{},"ISSN":["0196-0709"],"issn-type":[{"type":"print","value":"0196-0709"}],"subject":[],"published":{"date-parts":[[2009,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Clinical experiences with bisphosphonate-associated osteonecrosis of the jaws: analysis of 21 cases","name":"articletitle","label":"Article Title"},{"value":"American Journal of Otolaryngology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.amjoto.2008.07.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2009 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}