{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T15:44:33Z","timestamp":1776872673032,"version":"3.51.2"},"reference-count":30,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2012,3,1]],"date-time":"2012-03-01T00:00:00Z","timestamp":1330560000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,3,1]],"date-time":"2012-03-01T00:00:00Z","timestamp":1330560000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2012,3,1]],"date-time":"2012-03-01T00:00:00Z","timestamp":1330560000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2012,3,1]],"date-time":"2012-03-01T00:00:00Z","timestamp":1330560000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2012,3,1]],"date-time":"2012-03-01T00:00:00Z","timestamp":1330560000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2012,3,1]],"date-time":"2012-03-01T00:00:00Z","timestamp":1330560000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2012,3,1]],"date-time":"2012-03-01T00:00:00Z","timestamp":1330560000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Otolaryngology"],"published-print":{"date-parts":[[2012,3]]},"DOI":"10.1016\/j.amjoto.2010.08.001","type":"journal-article","created":{"date-parts":[[2010,10,30]],"date-time":"2010-10-30T08:21:12Z","timestamp":1288426872000},"page":"193-198","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"title":["Expression of nonclassical molecule human leukocyte antigen\u2013G in oral lesions"],"prefix":"10.1016","volume":"33","author":[{"given":"Paula A.G.","family":"Fregonezi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tarsia G.A.","family":"Silva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renata T.","family":"Sim\u00f5es","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philipe","family":"Moreau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edgardo D.","family":"Carosella","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carla P.M.","family":"Kl\u00e4y","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria A.G.","family":"Gon\u00e7alves","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edson G.","family":"Soares","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco","family":"Souto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eduardo A.","family":"Donadi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christiane P.","family":"Soares","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.amjoto.2010.08.001_bb0005","author":"Ferlay"},{"key":"10.1016\/j.amjoto.2010.08.001_bb0010","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1002\/j.0022-0337.2001.65.4.tb03403.x","article-title":"Tobacco use and oral cancer: a global perspective","volume":"65","author":"Johnson","year":"2001","journal-title":"J Dent Educ"},{"key":"10.1016\/j.amjoto.2010.08.001_bb0015","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1097\/CEJ.0b013e3282f75e91","article-title":"Alcohol and tobacco use, and cancer risk for upper aerodigestive tract and liver","volume":"17","author":"Pelucchi","year":"2008","journal-title":"Eur J Cancer Prev"},{"key":"10.1016\/j.amjoto.2010.08.001_bb0020","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1158\/1055-9965.EPI-04-0551","article-title":"Human papillomavirus types in head and neck squamous cell carcinomas worldwide: a systematic review","volume":"14","author":"Kreimer","year":"2005","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10.1016\/j.amjoto.2010.08.001_bb0025","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1007\/s10552-008-9183-0","article-title":"Dietary risk factors for squamous cell carcinoma of the upper aerodigestive tract in central and eastern Europe","volume":"19","author":"Sapkota","year":"2008","journal-title":"Cancer Causes Control"},{"key":"10.1016\/j.amjoto.2010.08.001_bb0030","doi-asserted-by":"crossref","first-page":"1772","DOI":"10.1093\/jnci\/djg107","article-title":"Human papillomavirus and oral cancer: the International Agency for Research on Cancer multicenter study","volume":"95","author":"Herrero","year":"2003","journal-title":"J Natl Cancer Inst"},{"key":"10.1016\/j.amjoto.2010.08.001_bb0035","first-page":"1","article-title":"Risk factors in oral and oropharyngeal squamous cell carcinoma: a population-based case-control study in southern Sweden","volume":"179","author":"Rosenquist","year":"2005","journal-title":"Swed Dent J"},{"key":"10.1016\/j.amjoto.2010.08.001_bb0040","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/S1368-8375(00)00066-X","article-title":"Influence of time delay and clinical upstaging in the prognosis of head and neck cancer","volume":"37","author":"Kowalski","year":"2001","journal-title":"Oral Oncol"},{"key":"10.1016\/j.amjoto.2010.08.001_bb0045","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1067\/mcd.2001.109374","article-title":"Cancer of the oral cavity","volume":"47","author":"Chen","year":"2001","journal-title":"Dis Mon"},{"key":"10.1016\/j.amjoto.2010.08.001_bb0050","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/0030-4220(86)90422-6","article-title":"Leukoplakia, lichen planus and other oral keratoses in 23,616 white Americans over the age of 35 years","volume":"61","author":"Bouquot","year":"1986","journal-title":"Oral Surg"},{"key":"10.1016\/j.amjoto.2010.08.001_bb0055","first-page":"133","article-title":"Oral leukoplakia-rationale for diagnosis and prognosis of its clinical subtypes or \u201cphases\u201d","volume":"25","author":"Bouquot","year":"1994","journal-title":"Quint Int"},{"key":"10.1016\/j.amjoto.2010.08.001_bb0060","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1126\/science.2326636","article-title":"A class I antigen, HLA-G, expressed in human trophoblasts","volume":"248","author":"Kovats","year":"1990","journal-title":"Science"},{"key":"10.1016\/j.amjoto.2010.08.001_bb0065","doi-asserted-by":"crossref","first-page":"11520","DOI":"10.1073\/pnas.94.21.11520","article-title":"Direct evidence to support the role of HLA-G in protecting the fetus from maternal uterine natural killer cytolysis","volume":"94","author":"Rouas-Freiss","year":"1997","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.amjoto.2010.08.001_bb0070","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/S0065-2776(03)81006-4","article-title":"HLA-G molecules: from maternal-fetal tolerance to tissue acceptance","volume":"81","author":"Carosella","year":"2003","journal-title":"Adv Immunol"},{"key":"10.1016\/j.amjoto.2010.08.001_bb0075","doi-asserted-by":"crossref","first-page":"10139","DOI":"10.1158\/0008-5472.CAN-05-0097","article-title":"HLA-G proteins in cancer: do they provide tumor cells with an escape mechanism?","volume":"65","author":"Rouas-Freiss","year":"2005","journal-title":"Cancer Res"},{"key":"10.1016\/j.amjoto.2010.08.001_bb0080","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.it.2007.11.005","article-title":"HLA-G: from biology to clinical benefits","volume":"29","author":"Carosella","year":"2008","journal-title":"Trends Immunol"},{"key":"10.1016\/j.amjoto.2010.08.001_bb0085","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1002\/ijc.11456","article-title":"Analysis of HLA antigen expression in benign and malignant melanocytic lesions reveals that upregulation of HLA-G expression correlates with malignant transformation, high inflammatory infiltration and HLA-A1 genotype","volume":"108","author":"Ibrahim","year":"2004","journal-title":"Int J Cancer"},{"key":"10.1016\/j.amjoto.2010.08.001_bb0090","first-page":"4107","article-title":"Functional role of human leukocyte antigen-G up-regulation in renal cell carcinoma","volume":"63","author":"Bukur","year":"2003","journal-title":"Cancer Res"},{"key":"10.1016\/j.amjoto.2010.08.001_bb0095","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1385\/IJGC:35:1:015","article-title":"HLA-G upregulation in pre-malignant and malignant lesions of the gastrointestinal tract","volume":"35","author":"Hansel","year":"2005","journal-title":"Int J Gastrointest Cancer"},{"key":"10.1016\/j.amjoto.2010.08.001_bb0100","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.ygyno.2004.09.049","article-title":"HLA-G expression in effusions is a possible marker of tumor susceptibility to chemotherapy in ovarian carcinoma","volume":"96","author":"Davidson","year":"2005","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.amjoto.2010.08.001_bb0105","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1159\/000326566","article-title":"PCR diagnosis of HPV in cervical biopsies of CIN and invasive neoplasia formerly diagnosed as HPV negative","volume":"47","author":"Bettini","year":"2003","journal-title":"Acta Cytol"},{"key":"10.1016\/j.amjoto.2010.08.001_bb0110","first-page":"209","article-title":"The use of polymerase chain reaction amplification for the detection of genital human papillomaviruses","volume":"7","author":"Manos","year":"1989","journal-title":"Cancer Cells"},{"key":"10.1016\/j.amjoto.2010.08.001_bb0115","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1002\/(SICI)1096-9896(199909)189:1<12::AID-PATH431>3.0.CO;2-F","article-title":"Human papillomavirus is a necessary cause of invasive cancer worldwide","volume":"189","author":"Walboomers","year":"1999","journal-title":"J Pathol"},{"key":"10.1016\/j.amjoto.2010.08.001_bb0120","first-page":"914","article-title":"Rapid silver staining and recovery of PCR products separated on polyacrylamide gels","volume":"5","author":"Sanguinetti","year":"1994","journal-title":"Biotechniques"},{"key":"10.1016\/j.amjoto.2010.08.001_bb0125","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1159\/000092537","article-title":"Cancer and pregnancy share similar mechanisms of immunological escape","volume":"52","author":"Wilczynski","year":"2006","journal-title":"Chemotherapy"},{"key":"10.1016\/j.amjoto.2010.08.001_bb0130","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.ejogrb.2008.06.010","article-title":"Classical and non-classical HLA molecules and p16 (INK4a) expression in precursors lesions and invasive cervical cancer","volume":"141","author":"Goncalves","year":"2008","journal-title":"Eur J Obstet Gynecol Reprod Biol 2008"},{"key":"10.1016\/j.amjoto.2010.08.001_bb0135","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1016\/j.humimm.2005.10.011","article-title":"Frequent HLA class I loss is an early event in cervical carcinogenesis","volume":"66","author":"Vermeulen","year":"2005","journal-title":"Hum Immunol"},{"key":"10.1016\/j.amjoto.2010.08.001_bb0140","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/j.ygyno.2007.02.016","article-title":"Expression and genetic analysis of transporter associated with antigen processing in cervical carcinoma","volume":"105","author":"Vermeulen","year":"2007","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.amjoto.2010.08.001_bb0145","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1002\/ijc.11217","article-title":"Selective expression of HLA-G in malignant and premalignant skin specimens in kidney transplant recipients","volume":"106","author":"Aractingi","year":"2003","journal-title":"Int J Cancer"},{"key":"10.1016\/j.amjoto.2010.08.001_bb0150","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/S0168-1702(02)00123-5","article-title":"Evasion of host immunity directed by papilloma virus\u2013encoded proteins","volume":"88","author":"O'brien","year":"2002","journal-title":"Virus Res"}],"container-title":["American Journal of Otolaryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S019607091000147X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S019607091000147X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,10,25]],"date-time":"2024-10-25T18:34:09Z","timestamp":1729881249000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S019607091000147X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,3]]},"references-count":30,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2012,3]]}},"alternative-id":["S019607091000147X"],"URL":"https:\/\/doi.org\/10.1016\/j.amjoto.2010.08.001","relation":{},"ISSN":["0196-0709"],"issn-type":[{"value":"0196-0709","type":"print"}],"subject":[],"published":{"date-parts":[[2012,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Expression of nonclassical molecule human leukocyte antigen\u2013G in oral lesions","name":"articletitle","label":"Article Title"},{"value":"American Journal of Otolaryngology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.amjoto.2010.08.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Crown copyright \u00a9 2012 Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}