{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T21:12:49Z","timestamp":1783977169517,"version":"3.55.0"},"reference-count":43,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T00:00:00Z","timestamp":1593561600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T00:00:00Z","timestamp":1593561600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["americanjournalofsurgery.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Surgery"],"published-print":{"date-parts":[[2020,7]]},"DOI":"10.1016\/j.amjsurg.2019.11.020","type":"journal-article","created":{"date-parts":[[2019,11,13]],"date-time":"2019-11-13T02:13:25Z","timestamp":1573611205000},"page":"170-177","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":27,"title":["Risk factors for ileocolic anastomosis dehiscence; a cohort study"],"prefix":"10.1016","volume":"220","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8770-3889","authenticated-orcid":false,"given":"Thomas","family":"Golda","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudio","family":"Lazzara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carla","family":"Zerpa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucia","family":"Sobrino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valeria","family":"Fico","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esther","family":"Kreisler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastiano","family":"Biondo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.amjsurg.2019.11.020_bib1","doi-asserted-by":"crossref","first-page":"1438","DOI":"10.1097\/DCR.0b013e31822c64f1","article-title":"Reoperation after colorectal surgery is an independent predictor of the 1-year mortality rate","volume":"54","author":"Westreenen","year":"2011","journal-title":"Dis Colon Rectum"},{"key":"10.1016\/j.amjsurg.2019.11.020_bib2","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1046\/j.1365-2168.2001.01719.x","article-title":"Outcome and late functional results after anastomotic leakage following mesorectal excision for rectal cancer","volume":"88","author":"Nesbakken","year":"2001","journal-title":"Br J Surg"},{"key":"10.1016\/j.amjsurg.2019.11.020_bib3","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1016\/j.ejso.2009.02.011","article-title":"Anastomotic leakage as a risk factor for the long-term outcome after curative resection of colon cancer","volume":"35","author":"Marra","year":"2009","journal-title":"Eur J Surg Oncol"},{"issue":"5","key":"10.1016\/j.amjsurg.2019.11.020_bib4","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1007\/s10350-004-6627-9","article-title":"Risk factors for anastomotic leakage after left-sided colorectal resection with rectal anastomosis","volume":"46","author":"M\u00e4kel\u00e4","year":"2003","journal-title":"Dis Colon Rectum"},{"key":"10.1016\/j.amjsurg.2019.11.020_bib5","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1097\/SLA.0b013e318262a6cd","article-title":"Identifying important predictors for anastomotic leak after colon and rectal resection: prospective study on 616 patients","volume":"257","author":"Trencheva","year":"2013","journal-title":"Ann Surg"},{"key":"10.1016\/j.amjsurg.2019.11.020_bib6","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1097\/01.sla.0000133185.23514.32","article-title":"Anterior resection for rectal cancer with mesorectal excision: a prospective evaluation of 622 patients","volume":"240","author":"Law","year":"2004","journal-title":"Ann Surg"},{"key":"10.1016\/j.amjsurg.2019.11.020_bib7","first-page":"784","article-title":"Risk factors for complications after ileocolonic resection for Crohn\u2019s disease with a major focus on the impact of preoperative immunosuppressive and biologic therapy: a retrospective international multicentre study","volume":"4","author":"Yamamoto","year":"2016","journal-title":"U\u00a0Eur Gastroenterol J"},{"key":"10.1016\/j.amjsurg.2019.11.020_bib8","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.surg.2009.10.012","article-title":"Definition and grading of anastomotic leakage following anterior resection of the rectum: a proposal by the International Study Group of Rectal Cancer","volume":"147","author":"Rahbari","year":"2010","journal-title":"Surgery"},{"key":"10.1016\/j.amjsurg.2019.11.020_bib9","doi-asserted-by":"crossref","first-page":"A43","DOI":"10.1016\/S0016-5085(98)80174-1","article-title":"Smoking and alcohol misuse are major risk factors of anastomotic leakage in colorectal surgery","volume":"114","author":"S\u00f8rensen","year":"2006","journal-title":"Gastroenterology"},{"key":"10.1016\/j.amjsurg.2019.11.020_bib10","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1097\/SLA.0000000000000973","article-title":"Risk factors for anastomotic leak after colon resection for cancer: multivariate analysis and nomogram from a multicentric, prospective, national study with 3193 patients","volume":"262","author":"Frasson","year":"2015","journal-title":"Ann Surg"},{"key":"10.1016\/j.amjsurg.2019.11.020_bib11","doi-asserted-by":"crossref","first-page":"1719","DOI":"10.1007\/s10350-006-0703-2","article-title":"Leakage after resection and intraperitoneal anastomosis for colorectal malignancy: analysis of risk factors","volume":"49","author":"Choi","year":"2006","journal-title":"Dis Colon Rectum"},{"key":"10.1016\/j.amjsurg.2019.11.020_bib12","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.ejso.2009.08.011","article-title":"Anastomotic leakage after colon cancer surgery: a predictor of significant morbidity and hospital mortality, and diminished tumour-free survival","volume":"36","author":"Kube","year":"2010","journal-title":"Eur J Surg Oncol"},{"key":"10.1016\/j.amjsurg.2019.11.020_bib13","doi-asserted-by":"crossref","first-page":"e661","DOI":"10.1111\/j.1463-1318.2012.03079.x","article-title":"A\u00a0nationwide study on anastomotic leakage after colonic cancer surgery","volume":"14","author":"Krarup","year":"2012","journal-title":"Colorect Dis: Off J Assoc Coloproctol G B Irel"},{"key":"10.1016\/j.amjsurg.2019.11.020_bib14","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1097\/DCR.0b013e3182423c0d","article-title":"Risk factors for anastomotic leakage after colectomy","volume":"55","author":"Leichtle","year":"2012","journal-title":"Dis Colon Rectum"},{"key":"10.1016\/j.amjsurg.2019.11.020_bib15","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1097\/01.sla.0000225083.27182.85","article-title":"Anastomotic leaks after intestinal anastomosis: it\u2019s later than you think","volume":"245","author":"Hyman","year":"2007","journal-title":"Ann Surg"},{"key":"10.1016\/j.amjsurg.2019.11.020_bib16","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/j.jamcollsurg.2007.06.284","article-title":"Anastomotic leakage after elective right versus left colectomy for cancer: prevalence and independent risk factors","volume":"205","author":"Veyrie","year":"2007","journal-title":"J\u00a0Am Coll Surg"},{"key":"10.1016\/j.amjsurg.2019.11.020_bib17","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1111\/codi.13212","article-title":"Anastomotic leakage after colon cancer resection: does the individual surgeon matter?","volume":"18","author":"Marinello","year":"2016","journal-title":"Colorect Dis: Off J Assoc Coloproctol G B Irel"},{"key":"10.1016\/j.amjsurg.2019.11.020_bib18","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1111\/codi.13938","article-title":"Risk factors for anastomotic leakage following ileosigmoid or ileorectal anastomosis","volume":"20","author":"Segelman","year":"2018","journal-title":"Colorect Dis: Off J Assoc Coloproctol G B Irel"},{"key":"10.1016\/j.amjsurg.2019.11.020_bib19","article-title":"The relationship between method of anastomosis and anastomotic failure after right hemicolectomy and ileo-caecal resection: an international snapshot audit","author":"2015 European Society of Coloproctology collaborating group","year":"2017","journal-title":"Colorect Dis: Off J Assoc Coloproctol G B Irel"},{"key":"10.1016\/j.amjsurg.2019.11.020_bib20","article-title":"Risk factors for unfavourable postoperative outcome in patients with Crohn\u2019s disease undergoing right hemicolectomy or ileocaecal resection. An international audit by ESCP and S-ECCO","volume":"20","author":"El-Hussuna","year":"2018","journal-title":"Colorect Dis: Off J Assoc Coloproctol G B Irel"},{"key":"10.1016\/j.amjsurg.2019.11.020_bib21","doi-asserted-by":"crossref","first-page":"1834","DOI":"10.1007\/s00268-015-2996-6","article-title":"Higher frequency of anastomotic leakage with stapled compared to hand-sewn ileocolic anastomosis in a large population-based study","volume":"39","author":"Gustafsson","year":"2015","journal-title":"World J Surg"},{"key":"10.1016\/j.amjsurg.2019.11.020_bib22","author":"Pyg"},{"key":"10.1016\/j.amjsurg.2019.11.020_bib23","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1001\/archsurg.1994.01420350077010","article-title":"Loss of colonic structural collagen impairs healing during intra-abdominal sepsis","volume":"129","author":"Ahrendt","year":"1994","journal-title":"Arch Surg"},{"key":"10.1016\/j.amjsurg.2019.11.020_bib24","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1001\/archsurg.2010.40","article-title":"Risk factors for anastomotic leak following colorectal surgery: a case-control study","volume":"145","author":"Telem","year":"2010","journal-title":"Arch Surg"},{"key":"10.1016\/j.amjsurg.2019.11.020_bib25","first-page":"299","article-title":"Host-related predictive factors for anastomotic leakage following large bowel resections for colorectal cancer","volume":"17","author":"Iancu","year":"2008","journal-title":"J.\u00a0Gastrointest. Liver Dis.: JGLD"},{"key":"10.1016\/j.amjsurg.2019.11.020_bib26","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1002\/bjs.4146","article-title":"Colonic anastomotic strength and matrix metalloproteinase activity in an experimental model of bacterial peritonitis","volume":"90","author":"IHJT De","year":"2003","journal-title":"Br J Surg"},{"key":"10.1016\/j.amjsurg.2019.11.020_bib27","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1007\/s00268-001-0256-4","article-title":"Factors associated with clinically significant anastomotic leakage after large bowel resection: multivariate analysis of 707 patients","volume":"26","author":"Alves","year":"2002","journal-title":"World J Surg"},{"key":"10.1016\/j.amjsurg.2019.11.020_bib28","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1097\/00000658-197305000-00002","article-title":"Factor contributing to leakage of colonic anastomoses","volume":"177","author":"Schrock","year":"1973","journal-title":"Ann Surg"},{"key":"10.1016\/j.amjsurg.2019.11.020_bib29","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1002\/bjs.1800750822","article-title":"Blood transfusion and infectious complications following colorectal cancer surgery","volume":"75","author":"Tartter","year":"1988","journal-title":"Br J Surg"},{"key":"10.1016\/j.amjsurg.2019.11.020_bib30","doi-asserted-by":"crossref","first-page":"1619","DOI":"10.1007\/s00384-016-2623-5","article-title":"Risk factors for clinical anastomotic leakage after right hemicolectomy","volume":"31","author":"Jessen","year":"2016","journal-title":"Int J Colorectal Dis"},{"key":"10.1016\/j.amjsurg.2019.11.020_bib31","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1159\/000049714","article-title":"Role of CD18-dependent neutrophil recruitment in skin and intestinal wound healing","volume":"33","author":"T\u00f6rkvist","year":"2001","journal-title":"Eur Surg Res"},{"key":"10.1016\/j.amjsurg.2019.11.020_bib32","doi-asserted-by":"crossref","first-page":"8836","DOI":"10.3748\/wjg.v21.i29.8787","article-title":"Role of the normal gut microbiota","volume":"21","author":"Jandhyala","year":"2015","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.amjsurg.2019.11.020_bib33","doi-asserted-by":"crossref","first-page":"1610","DOI":"10.3748\/wjg.v16.i13.1610","article-title":"Techniques for colorectal anastomosis","volume":"16","author":"Ho","year":"2010","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.amjsurg.2019.11.020_bib34","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1381\/0960892042583824","article-title":"Use of fibrin sealant in laparoscopic gastric bypass fo the morbidly obese","volume":"14","author":"Lee","year":"2004","journal-title":"Obes Surg"},{"key":"10.1016\/j.amjsurg.2019.11.020_bib35","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1381\/096089201321209350","article-title":"A\u00a0biodegradeable membrane from porcine intestinal submucosa to reinforce the gastrojejunostomy in laparoscopic Roux-en-Y gastric bypass: preliminary report","volume":"11","author":"Kini","year":"2001","journal-title":"Obes Surg"},{"key":"10.1016\/j.amjsurg.2019.11.020_bib36","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1007\/BF02237357","article-title":"Prospective evaluation of omentoplasty in preventing leakage of colorectal anastomosis","volume":"43","author":"Tocchi","year":"2000","journal-title":"Dis Colon Rectum"},{"key":"10.1016\/j.amjsurg.2019.11.020_bib37","doi-asserted-by":"crossref","first-page":"E232","DOI":"10.1111\/ans.13803","article-title":"Circumferentially oversewn inverted stapled anastomosis","volume":"88","author":"Karam","year":"2018","journal-title":"ANZ J Surg"},{"key":"10.1016\/j.amjsurg.2019.11.020_bib38","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1007\/s11605-015-2792-5","article-title":"Oversewing staple lines to prevent anastomotic complications in primary ileocolic resections for Crohn\u2019s disease","volume":"19","author":"Widmar","year":"2015","journal-title":"J\u00a0Gastrointest Surg: Off J Soc Surg Aliment Tract"},{"key":"10.1016\/j.amjsurg.2019.11.020_bib39","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1016\/j.amjsurg.2016.10.038","article-title":"Common side closure type, but not stapler brand or oversewing, influences side-to-side anastomotic leak rates","volume":"213","author":"Fleetwood","year":"2017","journal-title":"Am J Surg"},{"key":"10.1016\/j.amjsurg.2019.11.020_bib40","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1111\/codi.14308","article-title":"The impact of stapling technique and surgeon specialism on anastomotic failure after right-sided colorectal resection: an international multicentre, prospective audit","volume":"20","author":"Glasbey","year":"2018","journal-title":"Colorect Dis: Off J Assoc Coloproctol G B Irel"},{"key":"10.1016\/j.amjsurg.2019.11.020_bib41","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1002\/bjs.9395","article-title":"Risk factors for anastomotic leakage and leak-related mortality after colonic cancer surgery in a nationwide audit","volume":"101","author":"Bakker","year":"2014","journal-title":"Br J Surg"},{"key":"10.1016\/j.amjsurg.2019.11.020_bib42","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1097\/DCR.0000000000000392","article-title":"Association of comorbidity with anastomotic leak, 30-day mortality, and length of stay in elective surgery for colonic cancer: a nationwide cohort study","volume":"58","author":"Krarup","year":"2015","journal-title":"Dis Colon Rectum"},{"key":"10.1016\/j.amjsurg.2019.11.020_bib43","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1007\/s00384-016-2744-x","article-title":"Diagnosis, treatment, and consequences of anastomotic leakage in colorectal surgery","volume":"32","author":"Gessler","year":"2017","journal-title":"Int J Colorectal Dis"}],"container-title":["The American Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002961019312474?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002961019312474?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T18:18:35Z","timestamp":1757701115000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002961019312474"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7]]},"references-count":43,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,7]]}},"alternative-id":["S0002961019312474"],"URL":"https:\/\/doi.org\/10.1016\/j.amjsurg.2019.11.020","relation":{},"ISSN":["0002-9610"],"issn-type":[{"value":"0002-9610","type":"print"}],"subject":[],"published":{"date-parts":[[2020,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Risk factors for ileocolic anastomosis dehiscence; a cohort study","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.amjsurg.2019.11.020","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}