{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T23:56:31Z","timestamp":1791590191510,"version":"4.3.4"},"reference-count":28,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100005614","name":"BC Cancer Agency","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005614","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100015803","name":"BC Cancer Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100015803","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.com.au","clinicalkey.es","americanjournalofsurgery.com","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Surgery"],"published-print":{"date-parts":[[2024,5]]},"DOI":"10.1016\/j.amjsurg.2024.01.027","type":"journal-article","created":{"date-parts":[[2024,2,2]],"date-time":"2024-02-02T05:43:21Z","timestamp":1706852601000},"page":"120-124","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Impact of extra-nodal extension and AJCC lymph node staging in predicting recurrence following lymphadenectomy in patients with melanoma"],"prefix":"10.1016","volume":"231","author":[{"given":"Julia","family":"Downey","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeremy","family":"Hamm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Baliski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.amjsurg.2024.01.027_bib1","volume":"vol. 14","author":"Coit","year":"2016"},{"issue":"6","key":"10.1016\/j.amjsurg.2024.01.027_bib2","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1016\/S1470-2045(16)00141-8","article-title":"Complete lymph node dissection versus no dissection in patients with sentinel lymph node biopsy positive melanoma (DeCOG-SLT): a multicentre, randomised, phase 3 trial","volume":"17","author":"Leiter","year":"2016","journal-title":"Lancet Oncol"},{"issue":"23","key":"10.1016\/j.amjsurg.2024.01.027_bib3","doi-asserted-by":"crossref","first-page":"2211","DOI":"10.1056\/NEJMoa1613210","article-title":"Completion dissection or observation for sentinel-node metastasis in melanoma","volume":"376","author":"Faries","year":"2017","journal-title":"N\u00a0Engl J Med"},{"issue":"9","key":"10.1016\/j.amjsurg.2024.01.027_bib4","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1200\/JCO.2013.50.7681","article-title":"Nonsentinel lymph node status in patients with cutaneous melanoma: results from a multi-institution prognostic study","volume":"32","author":"Pasquali","year":"2014","journal-title":"J\u00a0Clin Oncol"},{"issue":"12","key":"10.1016\/j.amjsurg.2024.01.027_bib5","doi-asserted-by":"crossref","first-page":"3913","DOI":"10.1245\/s10434-012-2401-8","article-title":"Therapeutic lymph node dissection in melanoma: Different prognosis for different macrometastasis sites?","volume":"19","author":"Wevers","year":"2012","journal-title":"Ann Surg Oncol"},{"issue":"36","key":"10.1016\/j.amjsurg.2024.01.027_bib6","article-title":"Nodal basin recurrence after sentinel lymph node biopsy for melanoma: a retrospective multicenter study in 2653 patients","volume":"94","author":"Kretschmer","year":"2015","journal-title":"M\u00e9d"},{"issue":"4","key":"10.1016\/j.amjsurg.2024.01.027_bib7","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1097\/SLA.0b013e318161312a","article-title":"Morbidity and recurrence after completion lymph node dissection following sentinel lymph node biopsy in cutaneous malignant melanoma","volume":"247","author":"Guggenheim","year":"2008","journal-title":"Ann Surg"},{"issue":"6","key":"10.1016\/j.amjsurg.2024.01.027_bib8","doi-asserted-by":"crossref","first-page":"1970","DOI":"10.1245\/s10434-019-08086-0","article-title":"Regional node basin recurrence in melanoma patients: more common after node dissection for macroscopic rather than clinically occult nodal disease","volume":"27","author":"Uppal","year":"2020","journal-title":"Ann Surg Oncol"},{"issue":"9","key":"10.1016\/j.amjsurg.2024.01.027_bib9","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1001\/archsurg.1989.01410090061014","article-title":"Patterns of relapse in 1001 consecutive patients with melanoma nodal metastases","volume":"124","author":"Calabro","year":"1989","journal-title":"Arch Surg"},{"issue":"3","key":"10.1016\/j.amjsurg.2024.01.027_bib10","doi-asserted-by":"crossref","first-page":"1642","DOI":"10.1245\/s10434-020-09099-w","article-title":"Extracapsular spread in melanoma lymphadenopathy: prognostic implications, classification, and management","volume":"28","author":"Lo","year":"2021","journal-title":"Ann Surg Oncol"},{"issue":"13","key":"10.1016\/j.amjsurg.2024.01.027_bib11","doi-asserted-by":"crossref","first-page":"4370","DOI":"10.1245\/s10434-013-3186-0","article-title":"Limitations of lymph node ratio, evidence-based benchmarks, and the importance of a thorough lymph node dissection in melanoma","volume":"20","author":"Grotz","year":"2013","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.amjsurg.2024.01.027_bib12","doi-asserted-by":"crossref","first-page":"3925","DOI":"10.1200\/JCO.20.02110","article-title":"Longer follow-up confirms recurrence-free survival benefit of adjuvant pembrolizumab in high-risk stage III melanoma: updated results from the EORTC 1325-MG\/KEYNOTE-054 trial","volume":"38","author":"M Eggermont","year":"2020","journal-title":"J\u00a0Clin Oncol"},{"issue":"2","key":"10.1016\/j.amjsurg.2024.01.027_bib13","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1245\/s10434-021-10775-8","article-title":"Adjuvant therapy for stage III melanoma without immediate completion lymph node dissection","volume":"29","author":"Torphy","year":"2022","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.amjsurg.2024.01.027_bib14","unstructured":"Mitra D, Ologun G, Keung EZ, et\u00a0al. Nodal Recurrence Is a Primary Driver of Early Relapse for Patients with Sentinel Lymph Node-Positive Melanoma in the Modern Therapeutic Era. doi:10.1245\/s10434.."},{"issue":"12","key":"10.1016\/j.amjsurg.2024.01.027_bib15","doi-asserted-by":"crossref","first-page":"6978","DOI":"10.1245\/s10434-021-10570-5","article-title":"Surveillance of sentinel node-positive melanoma patients who receive adjuvant therapy without undergoing completion lymph node dissection","volume":"28","author":"Broman","year":"2021","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.amjsurg.2024.01.027_bib16","series-title":"AJCC Cancer Staging Manual","author":"Amin","year":"2017"},{"issue":"5","key":"10.1016\/j.amjsurg.2024.01.027_bib17","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1016\/j.amjsurg.2020.02.059","article-title":"Performance of models predicting residual lymph node disease in melanoma patients following sentinel lymph node biopsy","volume":"219","author":"MacDonald","year":"2020","journal-title":"Am J Surg"},{"key":"10.1016\/j.amjsurg.2024.01.027_bib18","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1200\/JCO.2017.75.7724","article-title":"Sentinel lymph node biopsy and management of regional lymph nodes in melanoma: American society of clinical oncology and society of surgical oncology clinical practice guideline update","volume":"36","author":"Wong","year":"2017","journal-title":"J\u00a0Clin Oncol"},{"issue":"2","key":"10.1016\/j.amjsurg.2024.01.027_bib19","first-page":"175","article-title":"Evolving management of positive regional lymph nodes in melanoma: past, present and future directions","volume":"13","author":"Fayne","year":"2019","journal-title":"Onco Rev"},{"key":"10.1016\/j.amjsurg.2024.01.027_bib20","doi-asserted-by":"crossref","first-page":"e505","DOI":"10.1200\/EDBK_159087","article-title":"Surgical management and adjuvant therapy for high-risk and metastatic melanoma","volume":"36","author":"Van Akkooi","year":"2016","journal-title":"Am Soc Clin Oncol Educ B"},{"issue":"13","key":"10.1016\/j.amjsurg.2024.01.027_bib21","doi-asserted-by":"crossref","first-page":"2251","DOI":"10.1002\/cncr.33483","article-title":"Active surveillance of patients who have sentinel node positive melanoma: an international, multi-institution evaluation of adoption and early outcomes after the Multicenter Selective Lymphadenectomy Trial II (MSLT-2)","volume":"127","author":"Broman","year":"2021","journal-title":"Cancer"},{"issue":"10","key":"10.1016\/j.amjsurg.2024.01.027_bib22","first-page":"1165","article-title":"Survival in patients with sentinel node\u2013positive melanoma with extranodal extension","volume":"19","author":"Maurichi","year":"2021","journal-title":"JNCCN J Natl Compr Cancer Netw"},{"issue":"2","key":"10.1016\/j.amjsurg.2024.01.027_bib23","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1007\/s10434-001-0109-2","article-title":"Risk factors for nodal recurrence after lymphadenectomy for melanoma","volume":"8","author":"Pidhorecky","year":"2001","journal-title":"Ann Surg Oncol"},{"issue":"24","key":"10.1016\/j.amjsurg.2024.01.027_bib24","doi-asserted-by":"crossref","first-page":"5836","DOI":"10.1002\/cncr.24627","article-title":"The benefits of adjuvant radiation therapy after therapeutic lymphadenectomy for clinically advanced, high-risk, lymph node-metastatic melanoma","volume":"115","author":"Agrawal","year":"2009","journal-title":"Cancer"},{"issue":"9","key":"10.1016\/j.amjsurg.2024.01.027_bib25","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1016\/S1470-2045(15)00187-4","article-title":"Adjuvant lymph-node field radiotherapy versus observation only in patients with melanoma at high risk of further lymph-node field relapse after lymphadenectomy (ANZMTG 01.02\/TROG 02.01): 6-year follow-up of a phase 3, randomised controlled trial","volume":"16","author":"Henderson","year":"2015","journal-title":"Lancet Oncol"},{"issue":"12","key":"10.1016\/j.amjsurg.2024.01.027_bib26","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1056\/NEJMoa2005493","article-title":"Five-year analysis of adjuvant dabrafenib plus trametinib in stage III melanoma","volume":"383","author":"Dummer","year":"2020","journal-title":"N\u00a0Engl J Med"},{"issue":"1","key":"10.1016\/j.amjsurg.2024.01.027_bib27","doi-asserted-by":"crossref","DOI":"10.1186\/1748-717X-6-12","article-title":"Adjuvant radiation therapy in metastatic lymph nodes from melanoma","volume":"6","author":"Bibault","year":"2011","journal-title":"Radiat Oncol"},{"issue":"3","key":"10.1016\/j.amjsurg.2024.01.027_bib28","doi-asserted-by":"crossref","first-page":"E394","DOI":"10.1503\/cjs.019320","article-title":"Population-based assessment of sentinel lymph node biopsy in the management of cutaneous melanoma","volume":"65","author":"Ollek","year":"2022","journal-title":"Can J Surg"}],"container-title":["The American Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002961024000291?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002961024000291?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,1,30]],"date-time":"2025-01-30T22:53:09Z","timestamp":1738277589000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002961024000291"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5]]},"references-count":28,"alternative-id":["S0002961024000291"],"URL":"https:\/\/doi.org\/10.1016\/j.amjsurg.2024.01.027","relation":{},"ISSN":["0002-9610"],"issn-type":[{"value":"0002-9610","type":"print"}],"subject":[],"published":{"date-parts":[[2024,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Impact of extra-nodal extension and AJCC lymph node staging in predicting recurrence following lymphadenectomy in patients with melanoma","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.amjsurg.2024.01.027","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Crown Copyright \u00a9 2024 Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}