{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T03:31:39Z","timestamp":1790220699749,"version":"4.1.0"},"reference-count":26,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["americanjournalofsurgery.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Surgery"],"published-print":{"date-parts":[[2026,2]]},"DOI":"10.1016\/j.amjsurg.2025.116777","type":"journal-article","created":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T07:58:09Z","timestamp":1765439889000},"page":"116777","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Intestinal discontinuity may be associated with worse outcomes in damage control laparotomy for trauma: An American association for the surgery of trauma prospective multicenter observational study"],"prefix":"10.1016","volume":"252","author":[{"given":"Elizabeth R.","family":"Benjamin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Demetrios","family":"Demetriades","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camilla","family":"Cremonini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anaar","family":"Siletz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Subarna","family":"Biswas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Mooney","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joe","family":"DuBose","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nori","family":"Bradley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David J.","family":"Skaurpa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucyna","family":"Krzywon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula","family":"Ferrada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pak S.","family":"Leung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John D.","family":"Berne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason","family":"Young","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas M.","family":"Scalea","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Harvin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Mull","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Turay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Pedersen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teena","family":"Dhir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dalier Rodriguez","family":"Mederos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riann","family":"Robbins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Goldenberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Butts","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dennis Yong","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grace","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian C.","family":"Thurston","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy V.","family":"Hamrick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alin","family":"Cheran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Magnone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.amjsurg.2025.116777_bib1","first-page":"666","article-title":"Damage control surgery: old concepts and new indications","volume":"29","author":"Chung","year":"2023","journal-title":"Curr Opin Crit Care"},{"issue":"3","key":"10.1016\/j.amjsurg.2025.116777_bib2","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1097\/00005373-199309000-00008","article-title":"'Damage control': an approach for improved survival in exsanguinating penetrating abdominal injury","volume":"35","author":"Rotondo","year":"1993","journal-title":"J Trauma"},{"issue":"1","key":"10.1016\/j.amjsurg.2025.116777_bib3","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1097\/TA.0b013e31827891ce","article-title":"Open abdominal management after damage-control laparotomy for trauma: a prospective observational American association for the surgery of trauma multicenter study","volume":"74","author":"Dubose","year":"2013","journal-title":"J Trauma Acute Care Surg"},{"issue":"6","key":"10.1016\/j.amjsurg.2025.116777_bib4","first-page":"726","article-title":"Management of the patient with the open abdomen","volume":"27","author":"Einav","year":"2021","journal-title":"Curr Opin Crit Care"},{"issue":"1","key":"10.1016\/j.amjsurg.2025.116777_bib5","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1186\/1749-7922-8-53","article-title":"Abdominal damage control surgery and reconstruction: world society of emergency surgery position paper","volume":"8","author":"Godat","year":"2013","journal-title":"World J Emerg Surg"},{"issue":"6","key":"10.1016\/j.amjsurg.2025.116777_bib6","doi-asserted-by":"crossref","first-page":"1568","DOI":"10.1016\/j.surg.2016.05.044","article-title":"Delayed interventions and mortality in trauma damage control laparotomy","volume":"160","author":"Lauerman","year":"2016","journal-title":"Surgery"},{"issue":"1","key":"10.1016\/j.amjsurg.2025.116777_bib7","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1177\/030006059602400103","article-title":"Bacterial translocation in experimental intestinal obstruction","volume":"24","author":"Ak\u00e7ay","year":"1996","journal-title":"J Int Med Res"},{"issue":"1","key":"10.1016\/j.amjsurg.2025.116777_bib8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1620\/tjem.198.1","article-title":"Effects of octreotide acetate and saccharomyces boulardii on bacterial translocation in an experimental intestinal loop obstruction model of rats","volume":"198","author":"Aldemir","year":"2002","journal-title":"Tohoku J Exp Med"},{"issue":"10","key":"10.1016\/j.amjsurg.2025.116777_bib9","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1001\/jamasurg.2013.2514","article-title":"Independent predictors of enteric fistula and abdominal sepsis after damage control laparotomy: results from the prospective AAST open abdomen registry","volume":"148","author":"Bradley","year":"2013","journal-title":"JAMA Surg"},{"issue":"2","key":"10.1016\/j.amjsurg.2025.116777_bib10","first-page":"273","article-title":"Sew it up! A Western trauma association multi-institutional study of enteric injury management in the postinjury open abdomen","volume":"70","author":"Burlew","year":"2011","journal-title":"J Trauma"},{"issue":"2","key":"10.1016\/j.amjsurg.2025.116777_bib11","doi-asserted-by":"crossref","first-page":"225","DOI":"10.2460\/ajvr.2001.62.225","article-title":"Effects of intraluminal distention and decompression on microvascular permeability and hemodynamics of the Equine jejunum","volume":"62","author":"Dabareiner","year":"2001","journal-title":"Am J Vet Res"},{"issue":"1","key":"10.1016\/j.amjsurg.2025.116777_bib12","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1007\/s00268-016-3685-9","article-title":"Discontinuity of the bowel following damage control operation revisited: a multi-institutional study","volume":"41","author":"Talving","year":"2017","journal-title":"World J Surg"},{"issue":"4","key":"10.1016\/j.amjsurg.2025.116777_bib13","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1111\/ans.18925","article-title":"The impact of stapled compared to handsewn repair on anastomotic outcomes in trauma patients: a systematic review and meta-analysis","volume":"94","author":"Le","year":"2024","journal-title":"ANZ J Surg"},{"issue":"4","key":"10.1016\/j.amjsurg.2025.116777_bib15","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1016\/S0002-9610(05)81280-2","article-title":"Obstructed intestine as a reservoir for systemic infection","volume":"159","author":"Deitch","year":"1990","journal-title":"Am J Surg"},{"issue":"1","key":"10.1016\/j.amjsurg.2025.116777_bib16","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.jss.2014.05.028","article-title":"Intraintestinal drainage as a damage control surgery adjunct in a hypothermic traumatic shock swine model with multiple bowel perforations","volume":"192","author":"Ji","year":"2014","journal-title":"J Surg Res"},{"issue":"9","key":"10.1016\/j.amjsurg.2025.116777_bib17","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1590\/S1807-59322009000900013","article-title":"Mesenteric microcirculatory dysfunctions and translocation of Indigenous bacteria in a rat model of strangulated small bowel obstruction","volume":"64","author":"Zanoni","year":"2009","journal-title":"Clinics"},{"issue":"5","key":"10.1016\/j.amjsurg.2025.116777_bib18","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1016\/0002-9610(82)90580-3","article-title":"Effects of intraluminal pressure on regional blood flow in obstructed and unobstructed small intestines in the rat","volume":"144","author":"Enochsson","year":"1982","journal-title":"Am J Surg"},{"issue":"6","key":"10.1016\/j.amjsurg.2025.116777_bib19","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1016\/j.amjsurg.2013.07.034","article-title":"Vasopressor use after initial damage control laparotomy increases risk for anastomotic disruption in the management of destructive colon injuries","volume":"206","author":"Fischer","year":"2013","journal-title":"Am J Surg"},{"key":"10.1016\/j.amjsurg.2025.116777_bib20","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/1471-2482-2-6","article-title":"Microscopy of bacterial translocation during small bowel obstruction and ischemia in vivo--a new animal model","volume":"2","author":"Samel","year":"2002","journal-title":"BMC Surg"},{"issue":"2","key":"10.1016\/j.amjsurg.2025.116777_bib21","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1016\/S0002-9610(88)80730-X","article-title":"Bacterial microflora, endogenous endotoxin, and prostaglandins in small bowel obstruction","volume":"155","author":"Roscher","year":"1988","journal-title":"Am J Surg"},{"issue":"6","key":"10.1016\/j.amjsurg.2025.116777_bib22","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1001\/archsurg.1989.01410060065013","article-title":"Simple intestinal obstruction causes bacterial translocation in man","volume":"124","author":"Deitch","year":"1989","journal-title":"Arch Surg"},{"issue":"6","key":"10.1016\/j.amjsurg.2025.116777_bib23","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1007\/BF02054126","article-title":"Intestinal obstruction promotes gut translocation of bacteria","volume":"38","author":"Sagar","year":"1995","journal-title":"Dis Colon Rectum"},{"issue":"6","key":"10.1016\/j.amjsurg.2025.116777_bib24","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1177\/000313480707300613","article-title":"Colonic resection in the setting of damage control laparotomy: is delayed anastomosis safe?","volume":"73","author":"Miller","year":"2007","journal-title":"Am Surg"},{"issue":"3","key":"10.1016\/j.amjsurg.2025.116777_bib25","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1007\/s00068-018-1013-9","article-title":"Postoperative complications of intestinal anastomosis after blunt abdominal trauma","volume":"46","author":"Mahmood","year":"2020","journal-title":"Eur J Trauma Emerg Surg"},{"issue":"6","key":"10.1016\/j.amjsurg.2025.116777_bib26","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1097\/TA.0000000000003513","article-title":"Destructive colon injuries requiring resection: is colostomy ever indicated?","volume":"92","author":"Mitchao","year":"2022","journal-title":"J Trauma Acute Care Surg"},{"issue":"3","key":"10.1016\/j.amjsurg.2025.116777_bib27","doi-asserted-by":"crossref","first-page":"2107","DOI":"10.1007\/s00068-021-01814-w","article-title":"Time is domain: factors affecting primary fascial closure after trauma and non-trauma damage control laparotomy (data from the EAST SLEEP-TIME multicenter registry)","volume":"48","author":"Kwon","year":"2022","journal-title":"Eur J Trauma Emerg Surg"}],"container-title":["The American Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002961025006002?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002961025006002?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T17:26:42Z","timestamp":1779298002000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002961025006002"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2]]},"references-count":26,"alternative-id":["S0002961025006002"],"URL":"https:\/\/doi.org\/10.1016\/j.amjsurg.2025.116777","relation":{},"ISSN":["0002-9610"],"issn-type":[{"value":"0002-9610","type":"print"}],"subject":[],"published":{"date-parts":[[2026,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Intestinal discontinuity may be associated with worse outcomes in damage control laparotomy for trauma: An American association for the surgery of trauma prospective multicenter observational study","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.amjsurg.2025.116777","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"116777"}}