{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T12:36:46Z","timestamp":1790339806705,"version":"4.1.0"},"reference-count":28,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2010,4,1]],"date-time":"2010-04-01T00:00:00Z","timestamp":1270080000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Anaerobe"],"published-print":{"date-parts":[[2010,4]]},"DOI":"10.1016\/j.anaerobe.2009.06.002","type":"journal-article","created":{"date-parts":[[2009,6,14]],"date-time":"2009-06-14T08:50:01Z","timestamp":1244969401000},"page":"155-160","source":"Crossref","is-referenced-by-count":32,"title":["Lethal toxin is a critical determinant of rapid mortality in rodent models of Clostridium sordellii endometritis"],"prefix":"10.1016","volume":"16","author":[{"given":"Yibai","family":"Hao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tennille","family":"Senn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judy S.","family":"Opp","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent B.","family":"Young","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teri","family":"Thiele","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geetha","family":"Srinivas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven K.","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David M.","family":"Aronoff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.anaerobe.2009.06.002_bib1","doi-asserted-by":"crossref","first-page":"1436","DOI":"10.1086\/508866","article-title":"Clostridium sordellii infection: epidemiology, clinical findings, and current perspectives on diagnosis and treatment","volume":"43","author":"Aldape","year":"2006","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.anaerobe.2009.06.002_bib2","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1001\/archinte.162.5.517","article-title":"Clostridial myonecrosis cluster among injection drug users: a molecular epidemiology investigation","volume":"162","author":"Bangsberg","year":"2002","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.anaerobe.2009.06.002_bib3","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1111\/j.1556-4029.2007.00452.x","article-title":"Necrotizing fasciitis: manifestations, microbiology and connection with black tar heroin","volume":"52","author":"Dunbar","year":"2007","journal-title":"J Forensic Sci"},{"key":"10.1016\/j.anaerobe.2009.06.002_bib4","doi-asserted-by":"crossref","first-page":"e87","DOI":"10.1086\/383471","article-title":"Outbreak of necrotizing fasciitis due to Clostridium sordellii among black-tar heroin users","volume":"38","author":"Kimura","year":"2004","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.anaerobe.2009.06.002_bib5","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1136\/jcp.50.3.259","article-title":"A fatal postpartum Clostridium sordellii associated toxic shock syndrome","volume":"50","author":"Bitti","year":"1997","journal-title":"J Clin Pathol"},{"key":"10.1016\/j.anaerobe.2009.06.002_bib6","doi-asserted-by":"crossref","first-page":"2352","DOI":"10.1056\/NEJMoa051620","article-title":"Fatal toxic shock syndrome associated with Clostridium sordellii after medical abortion","volume":"353","author":"Fischer","year":"2005","journal-title":"N Engl J Med"},{"key":"10.1016\/j.anaerobe.2009.06.002_bib7","doi-asserted-by":"crossref","first-page":"2564","DOI":"10.1056\/NEJMoa023222","article-title":"Clostridium infections associated with musculoskeletal-tissue allografts","volume":"350","author":"Kainer","year":"2004","journal-title":"N Engl J Med"},{"key":"10.1016\/j.anaerobe.2009.06.002_bib8","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1016\/0002-9378(89)90768-0","article-title":"Maternal deaths associated with Clostridium sordellii infection","volume":"161","author":"McGregor","year":"1989","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.anaerobe.2009.06.002_bib9","doi-asserted-by":"crossref","first-page":"1134","DOI":"10.1034\/j.1600-0412.2000.0790121134.x","article-title":"Postpartum Clostridium sordellii infection associated with fatal toxic shock syndrome","volume":"79","author":"Rorbye","year":"2000","journal-title":"Acta Obstet Gynecol Scand"},{"key":"10.1016\/j.anaerobe.2009.06.002_bib10","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1086\/344464","article-title":"Toxic shock syndrome due to Clostridium sordellii: a dramatic postpartum and postabortion disease","volume":"35","author":"Sinave","year":"2002","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.anaerobe.2009.06.002_bib11","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1016\/0002-9343(87)90790-X","article-title":"Infective endocarditis due to Clostridium sordellii","volume":"83","author":"Barnes","year":"1987","journal-title":"Am J Med"},{"key":"10.1016\/j.anaerobe.2009.06.002_bib12","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1097\/00006454-199008000-00011","article-title":"Clostridium sordellii infection and toxin neutralization","volume":"9","author":"Grimwood","year":"1990","journal-title":"Pediatr Infect Dis J"},{"key":"10.1016\/j.anaerobe.2009.06.002_bib13","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1097\/00005373-197506000-00011","article-title":"Clostridium sordelli infection","volume":"15","author":"Browdie","year":"1975","journal-title":"J Trauma"},{"key":"10.1016\/j.anaerobe.2009.06.002_bib14","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1111\/j.1574-6968.2006.00287.x","article-title":"Variations in lethal toxin and cholesterol-dependent cytolysin production correspond to differences in cytotoxicity among strains of Clostridium sordellii","volume":"259","author":"Voth","year":"2006","journal-title":"FEMS Microbiol Lett"},{"key":"10.1016\/j.anaerobe.2009.06.002_bib15","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1042\/bj0420590","article-title":"The biochemistry of bacterial toxins: 3. The identification and immunological relations of lecithinases present in Clostridium oedematiens and Clostridium sordellii toxins","volume":"42","author":"Macfarlane","year":"1948","journal-title":"Biochem J"},{"key":"10.1016\/j.anaerobe.2009.06.002_bib16","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1007\/BF01048368","article-title":"Purification and characterization of sialidase from Clostridium sordellii G12","volume":"4","author":"Roggentin","year":"1987","journal-title":"Glycoconjugate"},{"key":"10.1016\/j.anaerobe.2009.06.002_bib17","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1099\/00222615-2-1-37","article-title":"The toxins responsible for the lesions of Clostridium sordelli gas gangrene","volume":"2","author":"Arseculeratne","year":"1969","journal-title":"J Med Microbiol"},{"key":"10.1016\/j.anaerobe.2009.06.002_bib18","first-page":"1697","article-title":"Taxonomic position of lecithinase-negative strains of Clostridium sordellii","volume":"131","author":"Popoff","year":"1985","journal-title":"J Gen Microbiol"},{"key":"10.1016\/j.anaerobe.2009.06.002_bib19","first-page":"85","article-title":"Development of monoclonal antibodies suitable for use in antigen quantification potency tests for clostridial veterinary vaccines","volume":"101","author":"Hauer","year":"1999","journal-title":"Dev Biol Stand"},{"key":"10.1016\/j.anaerobe.2009.06.002_bib20","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1128\/IAI.71.2.641-646.2003","article-title":"Clostridium sordellii phospholipase C: gene cloning and comparison of enzymatic and biological activities with those of Clostridium perfringens and Clostridium bifermentans phospholipase C","volume":"71","author":"Karasawa","year":"2003","journal-title":"Infect Immun"},{"key":"10.1016\/j.anaerobe.2009.06.002_bib21","doi-asserted-by":"crossref","first-page":"8220","DOI":"10.4049\/jimmunol.180.12.8222","article-title":"Misoprostol impairs female reproductive tract innate immunity against Clostridium sordellii","volume":"180","author":"Aronoff","year":"2008","journal-title":"J Immunol"},{"key":"10.1016\/j.anaerobe.2009.06.002_bib22","first-page":"775","article-title":"An unusual fatal operative wound infection yielding a pathogenic anaerobe of the gas gangrene group not hitherto described; with direct reference to catgut as a source","volume":"45","author":"Meleney","year":"1927","journal-title":"Surg Gynecol Obstet"},{"key":"10.1016\/j.anaerobe.2009.06.002_bib23","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.2353\/ajpath.2007.060583","article-title":"Clostridium sordellii lethal toxin kills mice by inducing a major increase in lung vascular permeability","volume":"170","author":"Geny","year":"2007","journal-title":"Am J Pathol"},{"key":"10.1016\/j.anaerobe.2009.06.002_bib24","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1111\/j.1348-0421.1983.tb00611.x","article-title":"Cytotoxin production by Clostridium sordellii strains","volume":"27","author":"Nakamura","year":"1983","journal-title":"Microbiol Immunol"},{"key":"10.1016\/j.anaerobe.2009.06.002_bib25","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1097\/01.AOG.0000287291.19230.ba","article-title":"Toxic shock associated with Clostridium sordellii and Clostridium perfringens after medical and spontaneous abortion","volume":"110","author":"Cohen","year":"2007","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.anaerobe.2009.06.002_bib26","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1007\/s10254-004-0033-5","article-title":"Large clostridial cytotoxins","volume":"152","author":"Just","year":"2004","journal-title":"Rev Physiol Biochem Pharmacol"},{"key":"10.1016\/j.anaerobe.2009.06.002_bib27","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1128\/IAI.56.5.1215-1221.1988","article-title":"Purification and characterization of Clostridium sordellii hemorrhagic toxin and cross-reactivity with Clostridium difficile toxin A (enterotoxin)","volume":"56","author":"Martinez","year":"1988","journal-title":"Infect Immun"},{"key":"10.1016\/j.anaerobe.2009.06.002_bib28","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1128\/IAI.55.1.35-43.1987","article-title":"Purification and characterization of Clostridium sordellii lethal toxin and cross-reactivity with Clostridium difficile cytotoxin","volume":"55","author":"Popoff","year":"1987","journal-title":"Infect Immun"}],"container-title":["Anaerobe"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1075996409000870?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1075996409000870?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,3,14]],"date-time":"2024-03-14T15:39:21Z","timestamp":1710430761000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1075996409000870"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,4]]},"references-count":28,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2010,4]]}},"alternative-id":["S1075996409000870"],"URL":"https:\/\/doi.org\/10.1016\/j.anaerobe.2009.06.002","relation":{},"ISSN":["1075-9964"],"issn-type":[{"value":"1075-9964","type":"print"}],"subject":[],"published":{"date-parts":[[2010,4]]}}}