{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T00:11:58Z","timestamp":1774397518018,"version":"3.50.1"},"reference-count":14,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,2,1]],"date-time":"2015-02-01T00:00:00Z","timestamp":1422748800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Anaerobe"],"published-print":{"date-parts":[[2015,2]]},"DOI":"10.1016\/j.anaerobe.2014.08.002","type":"journal-article","created":{"date-parts":[[2014,8,17]],"date-time":"2014-08-17T12:30:15Z","timestamp":1408278615000},"page":"47-49","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"special_numbering":"C","title":["Investigation of the MICs of fidaxomicin and other antibiotics against Hungarian Clostridium difficile isolates"],"prefix":"10.1016","volume":"31","author":[{"given":"Zsuzsa","family":"Eitel","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriella","family":"Terhes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00f3zsef","family":"S\u00f3ki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisabeth","family":"Nagy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edit","family":"Urb\u00e1n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.anaerobe.2014.08.002_bib1","doi-asserted-by":"crossref","first-page":"1932","DOI":"10.1056\/NEJMra0707500","article-title":"Clostridium difficile: more difficult than ever","volume":"359","author":"Kelly","year":"2008","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.anaerobe.2014.08.002_bib2","doi-asserted-by":"crossref","first-page":"2403","DOI":"10.1128\/AAC.00090-08","article-title":"Both oral metronidazole and oral vancomycin promote persistant overgrowth of vancomycin-resistant enterococci during treatment of Clostridium difficile-associated disease","volume":"52","author":"Al-Nassir","year":"2008","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.anaerobe.2014.08.002_bib3","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/S1473-3099(05)70215-2","article-title":"Treatment of Clostridium difficile-associated disease: old therapies and new strategies","volume":"5","author":"Aslam","year":"2005","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.anaerobe.2014.08.002_bib4","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1111\/nyas.12135","article-title":"Advances in the treatment of Clostridium difficile with fidaxomicin: a narrow spectrum antibiotic","volume":"1290","author":"Sears","year":"2013","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.anaerobe.2014.08.002_bib5","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1128\/JCM.29.1.33-37.1991","article-title":"Identification of toxigenic Clostridium difficile by the polymerase chain reaction","volume":"29","author":"Kato","year":"1991","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.anaerobe.2014.08.002_bib6","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1111\/j.1574-6968.2000.tb09122.x","article-title":"Production of actin-specific ADP-ribosyltransferase (binary toxin) by strains of Clostridium difficile","volume":"186","author":"Stubbs","year":"2000","journal-title":"FEMS Microbiol Lett"},{"key":"10.1016\/j.anaerobe.2014.08.002_bib7","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.anaerobe.2009.01.010","article-title":"Assessment of changes in the epidemiology of Clostridium difficile isolated from diarrheal patients in Hungary","volume":"15","author":"Terhes","year":"2008","journal-title":"Anaerobe"},{"key":"10.1016\/j.anaerobe.2014.08.002_bib8","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1111\/j.1469-0691.2009.02807.x","article-title":"First isolation of Clostridium difficile PCR ribotype 027 from a patient with severe persistent diarrhoea in Hungary","volume":"15","author":"Terhes","year":"2009","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.anaerobe.2014.08.002_bib9","series-title":"Methods for antimicrobial susceptibility testing of anaerobic bacteria; approved standard-sixth ed","author":"Clinical and Laboratory Standards Institute","year":"2007"},{"key":"10.1016\/j.anaerobe.2014.08.002_bib10","doi-asserted-by":"crossref","first-page":"2716","DOI":"10.1128\/AAC.01623-06","article-title":"In vitro activities of 15 antimicrobial agents against 110 toxigenic Clostridium difficile clinical isolates collected from 1983 to 2004","volume":"51","author":"Hecht","year":"2007","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.anaerobe.2014.08.002_bib11","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.anaerobe.2009.09.005","article-title":"Typing and susceptibility of bacterial isolates from the fidaxomicin (OPT-80) phase II study for C. difficile infection","volume":"15","author":"Citron","year":"2009","journal-title":"Anaerobe"},{"issue":"Suppl.\u00a02","key":"10.1016\/j.anaerobe.2014.08.002_bib12","doi-asserted-by":"crossref","first-page":"S143","DOI":"10.1093\/cid\/cis339","article-title":"Antimicrobial activities of fidaxomicin","volume":"55","author":"Goldstein","year":"2012","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.anaerobe.2014.08.002_bib13","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.anaerobe.2014.07.001","article-title":"In\u00a0vitro activity of MCB3681 against Clostidium difficile strains","volume":"28","author":"Rashid","year":"2014","journal-title":"Anaerobe"},{"key":"10.1016\/j.anaerobe.2014.08.002_bib14","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1093\/jac\/dkt302","article-title":"In vitro selection, via serial passage, of Clostridium difficile mutants with reduced susceptibility to fidaxomicin or vancomycin","volume":"69","author":"Leeds","year":"2014","journal-title":"J Antimicrob Chemother"}],"container-title":["Anaerobe"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1075996414001085?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1075996414001085?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,8,23]],"date-time":"2020-08-23T11:58:46Z","timestamp":1598183926000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1075996414001085"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,2]]},"references-count":14,"alternative-id":["S1075996414001085"],"URL":"https:\/\/doi.org\/10.1016\/j.anaerobe.2014.08.002","relation":{},"ISSN":["1075-9964"],"issn-type":[{"value":"1075-9964","type":"print"}],"subject":[],"published":{"date-parts":[[2015,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Investigation of the MICs of fidaxomicin and other antibiotics against Hungarian Clostridium difficile isolates","name":"articletitle","label":"Article Title"},{"value":"Anaerobe","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.anaerobe.2014.08.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}