{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T15:20:29Z","timestamp":1761060029703},"reference-count":29,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,12,1]],"date-time":"2015-12-01T00:00:00Z","timestamp":1448928000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100004508","name":"Prince of Songkla University, Thailand","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004508","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Anaerobe"],"published-print":{"date-parts":[[2015,12]]},"DOI":"10.1016\/j.anaerobe.2015.10.012","type":"journal-article","created":{"date-parts":[[2015,11,4]],"date-time":"2015-11-04T10:07:17Z","timestamp":1446631637000},"page":"60-64","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Virulence of Aggregatibacter actinomycetemcomitans serotypes and DGGE subtypes isolated from chronic adult periodontitis in Thailand"],"prefix":"10.1016","volume":"36","author":[{"given":"Nuntiya","family":"Pahumunto","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Praphansri","family":"Ruangsri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mutita","family":"Wongsuwanlert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Supatcharin","family":"Piwat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gunnar","family":"Dahlen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rawee","family":"Teanpaisan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.anaerobe.2015.10.012_bib1","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1034\/j.1600-051X.29.s3.1.x","article-title":"Can presence or absence of periodontal pathogens distinguish between subjects with chronic and aggressive periodontitis? a systematic review","volume":"29","author":"Mombelli","year":"2002","journal-title":"J.\u00a0Clin. Periodontol."},{"key":"10.1016\/j.anaerobe.2015.10.012_bib2","doi-asserted-by":"crossref","DOI":"10.1016\/j.archoralbio.2015.09.003","article-title":"Aggregatibacter actinomycetemcomitans serotypes and DGGE subtypes in Thai adult chronic periodontitis","volume":"60","author":"Pahumunto","year":"2015","journal-title":"Arch. Oral Biol."},{"issue":"20","key":"10.1016\/j.anaerobe.2015.10.012_bib3","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1111\/j.1600-0757.1999.tb00160.x","article-title":"Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis in nonoral infections","volume":"2000","author":"van Winkelhoff","year":"1999","journal-title":"Periodontology"},{"key":"10.1016\/j.anaerobe.2015.10.012_bib4","doi-asserted-by":"crossref","first-page":"5375","DOI":"10.1128\/IAI.69.9.5375-5384.2001","article-title":"Structural and genetic analyses of O polysaccharide from Actinobacillus actinomycetemcomitans serotype f","volume":"69","author":"Kaplan","year":"2001","journal-title":"Infect. Immun."},{"key":"10.1016\/j.anaerobe.2015.10.012_bib5","doi-asserted-by":"crossref","first-page":"2002","DOI":"10.1128\/JCM.39.5.2002-2005.2001","article-title":"Identification of Actinobacillus actinomycetemcomitans serotypes by multiplex PCR","volume":"39","author":"Suzuki","year":"2001","journal-title":"J.\u00a0Clin. Microbiol."},{"key":"10.1016\/j.anaerobe.2015.10.012_bib6","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1007\/s00203-014-0965-3","article-title":"A\u00a0gene cluster for the synthesis of serotype g-specific polysaccharide antigen in Aggregatibacter actinomycetemcomitans","volume":"196","author":"Tsuzukibashi","year":"2014","journal-title":"Arch. Microbiol."},{"key":"10.1016\/j.anaerobe.2015.10.012_bib7","first-page":"1","article-title":"Pathogenicity of the highly leukotoxic JP2 clone of Aggregatibac- ter actinomycetemcomitans and its geographic dissemination and role in aggressive periodontitis","volume":"6","author":"Haubek","year":"2014","journal-title":"J.\u00a0Oral Microbiol."},{"key":"10.1016\/j.anaerobe.2015.10.012_bib8","first-page":"1","article-title":"Leukotoxic activity of Aggregatibacter actinomycetemcomitans and periodontal attachment loss","volume":"9","author":"\u00c5berg","year":"2014","journal-title":"Plos One"},{"key":"10.1016\/j.anaerobe.2015.10.012_bib9","first-page":"672","article-title":"Regulation of Actinobacillus actinomycetemcomitans leukotoxin expression: analysis of the promoter regions of leukotoxic and minimally leukotoxic strains","volume":"62","author":"Brogan","year":"1994","journal-title":"Infect. Dis."},{"key":"10.1016\/j.anaerobe.2015.10.012_bib10","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1111\/j.1600-0757.2009.00331.x","article-title":"Aggregatibacter (Actinobacillus) actinomycetemcomitans: a triple A* periodontopathogen?","volume":"54","author":"Henderson","year":"2010","journal-title":"Periodontol 2000"},{"key":"10.1016\/j.anaerobe.2015.10.012_bib11","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1111\/j.1600-0757.1999.tb00161.x","article-title":"Virulence factors of Actinobacillus actinomycetemcomitans","volume":"20","author":"Fives-Taylor","year":"1999","journal-title":"Periodontol 2000"},{"key":"10.1016\/j.anaerobe.2015.10.012_bib12","doi-asserted-by":"crossref","first-page":"2719","DOI":"10.1128\/IAI.59.8.2719-2726.1991","article-title":"Evidence for invasion of a human oral cell line by Actinobacillus actinomycetemcomitans","volume":"59","author":"Meyer","year":"1991","journal-title":"Infect. Immun."},{"key":"10.1016\/j.anaerobe.2015.10.012_bib13","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1128\/IAI.38.3.986-992.1982","article-title":"Inhibition of fibroblast proliferation by Actinobacil- lus actinomycetemcomitans","volume":"38","author":"Shenker","year":"1982","journal-title":"Infect. Immun."},{"key":"10.1016\/j.anaerobe.2015.10.012_bib14","doi-asserted-by":"crossref","first-page":"15451","DOI":"10.1016\/S0021-9258(19)84850-0","article-title":"Analysis of the Actinobacillus actinomycetemcomitans leukotoxin gene. Delineation of unique features and comparison to homologous toxins","volume":"264","author":"Lally","year":"1989","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.anaerobe.2015.10.012_bib15","doi-asserted-by":"crossref","first-page":"3037","DOI":"10.1128\/JCM.35.12.3037-3042.1997","article-title":"Racial tropism of a highly toxic clone of Actinobacillus actinomycetemcomitans associated with juvenile periodontitis","volume":"35","author":"Haubek","year":"1997","journal-title":"J.\u00a0Clin. Microbiol."},{"key":"10.1016\/j.anaerobe.2015.10.012_bib16","first-page":"1","article-title":"Detection of a 640-bp deletion in the Aggregatibacter actinomycetemcomitans leukotoxin promoter region in isolates from an adolescent of Ethiopian origin","volume":"7","author":"Claesson","year":"2015","journal-title":"J.\u00a0Oral Microbiol."},{"key":"10.1016\/j.anaerobe.2015.10.012_bib17","doi-asserted-by":"crossref","first-page":"4829","DOI":"10.1128\/JCM.41.10.4829-4832.2003","article-title":"Improved PCR for detection of the highly leukotoxic JP2 clone of Actinobacillus actinomycetemcomitans in subgingival plaque samples","volume":"41","author":"Poulsen","year":"2003","journal-title":"J.\u00a0Clin. Microbiol."},{"key":"10.1016\/j.anaerobe.2015.10.012_bib18","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1034\/j.1600-0765.2002.01618.x","article-title":"Cytolethal distending toxin of Actinobacillus actinomycetem- comitans. occurrence and association with periodontal disease","volume":"37","author":"Tan","year":"2002","journal-title":"J.\u00a0Periodontal Res."},{"key":"10.1016\/j.anaerobe.2015.10.012_bib19","first-page":"1","article-title":"Differential transcription of virulence genes in Aggregatibacter actinomycetemcomitans serotypes","volume":"5","author":"Umeda","year":"2013","journal-title":"J.\u00a0Oral Microbiol."},{"key":"10.1016\/j.anaerobe.2015.10.012_bib20","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1902\/jop.1999.70.11.1261","article-title":"A\u00a0novel insertion sequence increases the expression of leukotoxicity in Actinobacillus actinomycetemcomitans clinical isolates","volume":"70","author":"He","year":"1999","journal-title":"J.\u00a0Periodontol."},{"key":"10.1016\/j.anaerobe.2015.10.012_bib21","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1034\/j.1399-302X.2002.170301.x","article-title":"Actinobacillus actinomycetemcomitans in a rural adult population in southern Thailand","volume":"17","author":"Dahlen","year":"2002","journal-title":"Oral Microbiol. Immun."},{"key":"10.1016\/j.anaerobe.2015.10.012_bib22","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1111\/j.1600-051X.2012.01871.x","article-title":"Aggregatibacter actinomycetemcomitans serotypes, the JP2 clone and cytolethal distending toxin genes in a Thai population","volume":"39","author":"Bandhaya","year":"2012","journal-title":"J.\u00a0Clin. Periodontol."},{"key":"10.1016\/j.anaerobe.2015.10.012_bib23","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1034\/j.1600-051X.1999.260803.x","article-title":"Actinobacillus actinomycetemcomitans in Chinese adults: serotype distribution and analysis of the leukotoxin gene promoter locus","volume":"26","author":"Mombelli","year":"1999","journal-title":"J.\u00a0Clin. Periodontol."},{"key":"10.1016\/j.anaerobe.2015.10.012_bib24","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1034\/j.1399-302X.2003.00034.x","article-title":"Distribution of Actinobacillus actinomycetemcomitans serotypes and Porphyromonas gingivalis in Japanese adults","volume":"18","author":"Yoshida","year":"2003","journal-title":"Oral Microbiol. Immunol."},{"key":"10.1016\/j.anaerobe.2015.10.012_bib25","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1128\/JCM.40.4.1181-1187.2002","article-title":"Population structure and genetic diversity of Actinobacillus actinomycetemcomitans strains isolated from localized juvenile periodontitis patients","volume":"40","author":"Kaplan","year":"2002","journal-title":"J.\u00a0Clin. Microbiol."},{"key":"10.1016\/j.anaerobe.2015.10.012_bib26","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1111\/j.1399-302X.2009.00547.x","article-title":"Genetic diversity and toxic activity of Aggregatibacter actinomycetemcomitans isolates","volume":"24","author":"Kawamoto","year":"2009","journal-title":"Oral Microbiol. Immunol."},{"key":"10.1016\/j.anaerobe.2015.10.012_bib27","doi-asserted-by":"crossref","first-page":"964","DOI":"10.1016\/j.archoralbio.2012.01.014","article-title":"Infection of human gingival fibroblasts with Aggregatibacter actinomycetemcomitans: an in\u00a0vitro study","volume":"57","author":"Arirachakaran","year":"2012","journal-title":"Arch. Oral Biol."},{"key":"10.1016\/j.anaerobe.2015.10.012_bib28","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1099\/00222615-35-1-5","article-title":"Age-related microbiological changes in the salivary and plaque microflora of healthy adults","volume":"35","author":"Percival","year":"1991","journal-title":"J.\u00a0Med. Microbiol."},{"key":"10.1016\/j.anaerobe.2015.10.012_bib29","series-title":"Ageing Theories, Diseases and Microorganisms. Microbiology and Aging","first-page":"1","author":"Percival","year":"2009"}],"container-title":["Anaerobe"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S107599641530072X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S107599641530072X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,5,25]],"date-time":"2022-05-25T04:14:44Z","timestamp":1653452084000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S107599641530072X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12]]},"references-count":29,"alternative-id":["S107599641530072X"],"URL":"https:\/\/doi.org\/10.1016\/j.anaerobe.2015.10.012","relation":{},"ISSN":["1075-9964"],"issn-type":[{"value":"1075-9964","type":"print"}],"subject":[],"published":{"date-parts":[[2015,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Virulence of Aggregatibacter actinomycetemcomitans serotypes and DGGE subtypes isolated from chronic adult periodontitis in Thailand","name":"articletitle","label":"Article Title"},{"value":"Anaerobe","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.anaerobe.2015.10.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}