{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T14:32:40Z","timestamp":1789655560435,"version":"4.0.1"},"reference-count":15,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2011,7,1]],"date-time":"2011-07-01T00:00:00Z","timestamp":1309478400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,7,1]],"date-time":"2011-07-01T00:00:00Z","timestamp":1309478400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["annallergy.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annals of Allergy, Asthma &amp; Immunology"],"published-print":{"date-parts":[[2011,7]]},"DOI":"10.1016\/j.anai.2011.03.005","type":"journal-article","created":{"date-parts":[[2011,4,20]],"date-time":"2011-04-20T07:09:47Z","timestamp":1303283387000},"page":"65-70","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":77,"title":["Persistence of effectiveness of bronchial thermoplasty in patients with severe asthma"],"prefix":"10.1016","volume":"107","author":[{"given":"Mario","family":"Castro","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adalberto","family":"Rubin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel","family":"Laviolette","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicola A.","family":"Hanania","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian","family":"Armstrong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerard","family":"Cox","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.anai.2011.03.005_bib1","series-title":"National Health Interview Survey, National Center for Health Statistics, CDC","year":"2009"},{"key":"10.1016\/j.anai.2011.03.005_bib2","unstructured":"American Lung Association. Epidemiology & Statistics Unit, Research and Program Services. Trends in Asthma Morbidity and Mortality, November 2007."},{"key":"10.1016\/j.anai.2011.03.005_bib3","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/j.jaci.2006.11.639","article-title":"Characterization of the severe asthma phenotype by the National Heart, Lung, and Blood Institute's Severe Asthma Research Program","volume":"119","author":"Moore","year":"2007","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.anai.2011.03.005_bib4","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1056\/NEJMoa064707","article-title":"Asthma control during the year after bronchial thermoplasty","volume":"356","author":"Cox","year":"2007","journal-title":"N Engl J Med"},{"key":"10.1016\/j.anai.2011.03.005_bib5","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1164\/rccm.200903-0354OC","article-title":"Effectiveness and safety of bronchial thermoplasty in the treatment of severe asthma: a multicenter, randomized, double-blind, sham-controlled clinical trial","volume":"181","author":"Castro","year":"2010","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.anai.2011.03.005_bib6","first-page":"A567","article-title":"Long-term follow-up of bronchial thermoplasty for asthma: Safety results at 5 years","volume":"177","author":"Cox","year":"2008","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.anai.2011.03.005_bib7","first-page":"A2780","article-title":"Long term safety of bronchial thermoplasty (BT): 3 Year data from multiple studies","volume":"179","author":"Cox","year":"2009","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.anai.2011.03.005_bib8","doi-asserted-by":"crossref","first-page":"1422","DOI":"10.2307\/2533508","article-title":"Establishing equivalence of two treatments and sample size requirements in matched pairs design","volume":"53","author":"Nam","year":"1997","journal-title":"Biometrics"},{"key":"10.1016\/j.anai.2011.03.005_bib9","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1136\/thx.47.2.76","article-title":"Evaluation of impairment of health related quality of life in asthma: development of a questionnaire for use in clinical trials","volume":"47","author":"Juniper","year":"1992","journal-title":"Thorax"},{"key":"10.1016\/j.anai.2011.03.005_bib11","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1164\/rccm.200507-1162OC","article-title":"Bronchial thermoplasty for asthma","volume":"173","author":"Cox","year":"2006","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.anai.2011.03.005_bib12","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1164\/rccm.200704-571OC","article-title":"Safety and efficacy of bronchial thermoplasty in symptomatic, severe asthma","volume":"176","author":"Pavord","year":"2007","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.anai.2011.03.005_bib13","doi-asserted-by":"crossref","first-page":"1946","DOI":"10.1152\/japplphysiol.01282.2003","article-title":"Reduction in airway hyperresponsiveness to methacholine by the application of RF energy in dogs","volume":"97","author":"Danek","year":"2004","journal-title":"J Appl Physiol"},{"key":"10.1016\/j.anai.2011.03.005_bib14","series-title":"International Conference on Harmonisation ICH Topic E9: Statistical principles for clinical trials","year":"1998"},{"key":"10.1016\/j.anai.2011.03.005_bib15","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1111\/j.1365-2222.2004.1916.x","article-title":"Efficacy and safety of a recombinant anti-immunoglobulin E antibody (omalizumab) in severe allergic asthma","volume":"34","author":"Holgate","year":"2004","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.anai.2011.03.005_bib16","series-title":"Expert panel report 3: Guidelines for the diagnosis and management of asthma","year":"2007"}],"container-title":["Annals of Allergy, Asthma &amp; Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1081120611001852?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1081120611001852?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T13:05:12Z","timestamp":1761051912000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1081120611001852"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,7]]},"references-count":15,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2011,7]]}},"alternative-id":["S1081120611001852"],"URL":"https:\/\/doi.org\/10.1016\/j.anai.2011.03.005","relation":{},"ISSN":["1081-1206"],"issn-type":[{"value":"1081-1206","type":"print"}],"subject":[],"published":{"date-parts":[[2011,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Persistence of effectiveness of bronchial thermoplasty in patients with severe asthma","name":"articletitle","label":"Article Title"},{"value":"Annals of Allergy, Asthma & Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.anai.2011.03.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 American College of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}