{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T08:41:29Z","timestamp":1761986489087,"version":"build-2065373602"},"reference-count":31,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2015,10,1]],"date-time":"2015-10-01T00:00:00Z","timestamp":1443657600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,10,1]],"date-time":"2015-10-01T00:00:00Z","timestamp":1443657600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["annallergy.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annals of Allergy, Asthma & Immunology"],"published-print":{"date-parts":[[2015,10]]},"DOI":"10.1016\/j.anai.2015.07.012","type":"journal-article","created":{"date-parts":[[2015,8,11]],"date-time":"2015-08-11T00:15:59Z","timestamp":1439252159000},"page":"282-287","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["Relationship between in utero C-reactive protein levels and asthma in at-risk children"],"prefix":"10.1016","volume":"115","author":[{"given":"Brittany","family":"Lapin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dennis","family":"Ownby","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary","family":"Turyk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julie","family":"Piorkowski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sally","family":"Freels","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noel","family":"Chavez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cynthia","family":"Wagner-Cassanova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eva","family":"Hernandez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Darlene","family":"Pelzel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carmen","family":"Vergara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victoria","family":"Persky","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.anai.2015.07.012_bib1","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1046\/j.0022-0477.2001.01267.x","article-title":"Antenatal determinants of neonatal immune responses to allergens","volume":"32","author":"Devereux","year":"2002","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.anai.2015.07.012_bib2","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1111\/cea.12332","article-title":"The gut microbiota and its role in the development of allergic disease: a wider perspective","volume":"45","author":"West","year":"2015","journal-title":"Clin Exp Allergy"},{"issue":"suppl 1","key":"10.1016\/j.anai.2015.07.012_bib3","doi-asserted-by":"crossref","first-page":"S75","DOI":"10.1111\/j.1600-0897.2011.01036.x","article-title":"Childhood immune maturation and allergy development: regulation by maternal immunity and microbial exposure","volume":"66","author":"Jenmalm","year":"2011","journal-title":"Am J Reprod Immunol"},{"key":"10.1016\/j.anai.2015.07.012_bib4","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1038\/nri3112","article-title":"The impact of perinatal immune development on mucosal homeostasis and chronic inflammation","volume":"12","author":"Renz","year":"2012","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.anai.2015.07.012_bib5","doi-asserted-by":"crossref","first-page":"1805","DOI":"10.1172\/JCI200318921","article-title":"C-reactive protein: a critical update","volume":"111","author":"Pepys","year":"2003","journal-title":"J\u00a0Clin Invest"},{"key":"10.1016\/j.anai.2015.07.012_bib6","doi-asserted-by":"crossref","first-page":"164.e1","DOI":"10.1016\/j.ajog.2010.08.056","article-title":"Maternal C-reactive protein levels in pregnancy are associated with wheezing and lower respiratory tract infections in the offspring","volume":"204","author":"Morales","year":"2011","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.anai.2015.07.012_bib7","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1111\/pai.12094","article-title":"Influence of maternal and cord blood C-reactive protein on childhood respiratory symptoms and eczema","volume":"24","author":"Sonnenschein-van der Voort","year":"2013","journal-title":"Pediatr Allergy Immunol"},{"key":"10.1016\/j.anai.2015.07.012_bib8","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1097\/00006454-199708000-00003","article-title":"Clinical applications of C-reactive protein in pediatrics","volume":"16","author":"Jaye","year":"1997","journal-title":"Pediatr Infect Dis J"},{"issue":"Suppl 1","key":"10.1016\/j.anai.2015.07.012_bib9","doi-asserted-by":"crossref","first-page":"S216","DOI":"10.1378\/chest.116.suppl_2.216S","article-title":"Chicago community-based asthma intervention trial: feasibility of delivering peer education in an inner-city population","volume":"116","author":"Persky","year":"1999","journal-title":"Chest"},{"key":"10.1016\/j.anai.2015.07.012_bib10","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1016\/S1081-1206(10)60264-5","article-title":"The effect of low-cost modification of the home environment on the development of respiratory symptoms in the first year of life","volume":"103","author":"Persky","year":"2009","journal-title":"Ann Allergy Asthma Immunol"},{"key":"10.1016\/j.anai.2015.07.012_bib11","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/S1081-1206(10)60492-9","article-title":"Prenatal exposure to acetaminophen and respiratory symptoms in the first year of life","volume":"101","author":"Persky","year":"2008","journal-title":"Ann Allergy Asthma Immunol"},{"key":"10.1016\/j.anai.2015.07.012_bib12","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1001\/archpedi.156.3.269","article-title":"Identification of population subgroups of children and adolescents with high asthma prevalence: findings from the Third National Health and Nutrition Examination Survey","volume":"156","author":"Rodriguez","year":"2002","journal-title":"Arch Pediatr Adolesc Med"},{"key":"10.1016\/j.anai.2015.07.012_bib13","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1542\/peds.2004-1714","article-title":"Heterogeneity of childhood asthma among Hispanic children: Puerto Rican children bear a disproportionate burden","volume":"117","author":"Lara","year":"2006","journal-title":"Pediatrics"},{"key":"10.1016\/j.anai.2015.07.012_bib14","doi-asserted-by":"crossref","first-page":"929","DOI":"10.2105\/AJPH.90.6.929","article-title":"Asthma and Latino cultures: different prevalence reported among groups sharing the same environment","volume":"90","author":"Ledogar","year":"2000","journal-title":"Am J Public Health"},{"key":"10.1016\/j.anai.2015.07.012_bib15","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1038\/sj.jea.7500266","article-title":"Household exposure factors, asthma, and school absenteeism in a predominantly Hispanic community","volume":"13","author":"Freeman","year":"2003","journal-title":"J\u00a0Expo Anal Environ Epidemiol"},{"key":"10.1016\/j.anai.2015.07.012_bib16","doi-asserted-by":"crossref","first-page":"580","DOI":"10.2105\/AJPH.83.4.580","article-title":"Reported asthma among Puerto Rican, Mexican-American, and Cuban children, 1982 through 1984","volume":"83","author":"Carter-Pokras","year":"1993","journal-title":"Am J Public Health"},{"key":"10.1016\/j.anai.2015.07.012_bib17","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1093\/jpepsy\/jsr041","article-title":"Immigration and acculturation-related factors and asthma morbidity in Latino children","volume":"36","author":"Koinis-Mitchell","year":"2011","journal-title":"J\u00a0Pediatr Psychol"},{"key":"10.1016\/j.anai.2015.07.012_bib18","doi-asserted-by":"crossref","first-page":"1753","DOI":"10.1378\/chest.06-3008","article-title":"Increased risk of childhood asthma from antibiotic use in early life","volume":"131","author":"Kozyrskyj","year":"2007","journal-title":"Chest"},{"key":"10.1016\/j.anai.2015.07.012_bib19","doi-asserted-by":"crossref","first-page":"523.e1","DOI":"10.1016\/j.ajog.2008.04.017","article-title":"Racial differences in C-reactive protein levels during normal pregnancy","volume":"199","author":"Picklesimer","year":"2008","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.anai.2015.07.012_bib20","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1093\/humrep\/deh179","article-title":"Maternal C-reactive protein levels are raised at 4 weeks gestation","volume":"19","author":"Sacks","year":"2004","journal-title":"Hum Reprod"},{"key":"10.1016\/j.anai.2015.07.012_bib21","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.ejogrb.2005.02.022","article-title":"Fluctuations in C-reactive protein concentration and neutrophil activation during normal human pregnancy","volume":"123","author":"Belo","year":"2005","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"10.1016\/j.anai.2015.07.012_bib22","doi-asserted-by":"crossref","first-page":"113","DOI":"10.3349\/ymj.2014.55.1.113","article-title":"Positive maternal C-reactive protein predicts neonatal sepsis","volume":"55","author":"Jeon","year":"2014","journal-title":"Yonsei Med J"},{"key":"10.1016\/j.anai.2015.07.012_bib23","doi-asserted-by":"crossref","first-page":"132.e1","DOI":"10.1016\/j.ajog.2011.03.049","article-title":"C-reactive protein levels in early pregnancy, fetal growth patterns, and the risk for neonatal complications: the Generation R Study","volume":"205","author":"Ernst","year":"2011","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.anai.2015.07.012_bib24","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1016\/j.clinbiochem.2006.11.017","article-title":"Maternal serum C-reactive protein concentrations in early pregnancy and subsequent risk of preterm delivery","volume":"40","author":"Lohsoonthorn","year":"2007","journal-title":"Clin Biochem"},{"key":"10.1016\/j.anai.2015.07.012_bib25","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/S0165-0378(02)00085-2","article-title":"Elevated C-reactive protein levels during first trimester of pregnancy are indicative of preeclampsia and intrauterine growth restriction","volume":"59","author":"Tjoa","year":"2003","journal-title":"J\u00a0Reprod Immunol"},{"key":"10.1016\/j.anai.2015.07.012_bib26","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1111\/j.1440-1843.2007.01122.x","article-title":"Association between asthma, asthma symptoms and C-reactive protein in US adults: data from the National Health and Nutrition Examination Survey, 1999\u20132002","volume":"12","author":"Arif","year":"2007","journal-title":"Respirology"},{"key":"10.1016\/j.anai.2015.07.012_bib27","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1183\/09031936.00040708","article-title":"High-sensitive C-reactive protein is associated with reduced lung function in young adults","volume":"33","author":"Rasmussen","year":"2009","journal-title":"Eur Respir J"},{"key":"10.1016\/j.anai.2015.07.012_bib28","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1016\/S0140-6736(03)14542-4","article-title":"Association between antenatal cytokine production and the development of atopy and asthma at age 6 years","volume":"362","author":"Macaubas","year":"2003","journal-title":"Lancet"},{"key":"10.1016\/j.anai.2015.07.012_bib29","doi-asserted-by":"crossref","first-page":"2226","DOI":"10.1056\/NEJMra054308","article-title":"The asthma epidemic","volume":"355","author":"Eder","year":"2006","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.anai.2015.07.012_bib30","first-page":"652","article-title":"Analytical performance of a highly sensitive C-reactive protein-based immunoassay and the effects of laboratory variables on levels of protein in blood","volume":"10","author":"Aziz","year":"2003","journal-title":"Clin Diagn Lab Immunol"},{"key":"10.1016\/j.anai.2015.07.012_bib31","first-page":"120","article-title":"Comparison of C-reactive protein levels between serum and plasma samples on long-term frozen storage after a 13.8 year interval: the JMS Cohort Study","volume":"17","author":"Ishikawa","year":"2007","journal-title":"J\u00a0Epidemiol"}],"container-title":["Annals of Allergy, Asthma & Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1081120615004810?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1081120615004810?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T13:13:12Z","timestamp":1761052392000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1081120615004810"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,10]]},"references-count":31,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2015,10]]}},"alternative-id":["S1081120615004810"],"URL":"https:\/\/doi.org\/10.1016\/j.anai.2015.07.012","relation":{},"ISSN":["1081-1206"],"issn-type":[{"type":"print","value":"1081-1206"}],"subject":[],"published":{"date-parts":[[2015,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Relationship between in utero C-reactive protein levels and asthma in at-risk children","name":"articletitle","label":"Article Title"},{"value":"Annals of Allergy, Asthma & Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.anai.2015.07.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 American College of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}