{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T19:44:57Z","timestamp":1775677497645,"version":"3.50.1"},"reference-count":40,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2016,5,1]],"date-time":"2016-05-01T00:00:00Z","timestamp":1462060800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,5,1]],"date-time":"2016-05-01T00:00:00Z","timestamp":1462060800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["annallergy.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annals of Allergy, Asthma & Immunology"],"published-print":{"date-parts":[[2016,5]]},"DOI":"10.1016\/j.anai.2016.03.007","type":"journal-article","created":{"date-parts":[[2016,4,2]],"date-time":"2016-04-02T22:57:09Z","timestamp":1459637829000},"page":"402-407","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Clinical characteristics of asthmatic patients with influenza-like illness and risk of severe exacerbations in Mexico"],"prefix":"10.1016","volume":"116","author":[{"given":"Paulina","family":"Paulin-Prado","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katherine","family":"Nishimura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Freimanis-Hance","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sally","family":"Hunsberger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Beigel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arturo Galindo","family":"Fraga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana A.","family":"Ortiz Hernandez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beatriz","family":"Llamosas-Gallardo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarbelio","family":"Moreno-Espinosa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Maga\u00f1a-Aquino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guillermo M.","family":"Ruiz Palacios","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alejandra","family":"Ramirez-Venegas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.anai.2016.03.007_bib1","series-title":"World Health Report 2002","year":"2002"},{"key":"10.1016\/j.anai.2016.03.007_bib2","doi-asserted-by":"crossref","first-page":"293","DOI":"10.3389\/fmicb.2013.00293","article-title":"Virus-induced exacerbations in asthma and COPD","volume":"4","author":"Kurai","year":"2013","journal-title":"Front Microbiol"},{"key":"10.1016\/j.anai.2016.03.007_bib3","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1165\/rcmb.2006-0199TR","article-title":"Role of viral infections in asthma and chronic obstructive pulmonary disease","volume":"35","author":"Proud","year":"2006","journal-title":"Am J Respir Cell Mol Biol"},{"key":"10.1016\/j.anai.2016.03.007_bib4","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1378\/chest.112.3.591","article-title":"The incidence of respiratory tract infection in adults requiring hospitalization for asthma","volume":"112","author":"Teichtahl","year":"1997","journal-title":"Chest"},{"key":"10.1016\/j.anai.2016.03.007_bib5","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/S0002-9343(03)00353-X","article-title":"Epidemiology of respiratory viruses in patients hospitalized with near-fatal asthma, acute exacerbations of asthma, or chronic obstructive pulmonary disease","volume":"115","author":"Tan","year":"2003","journal-title":"Am J Med"},{"key":"10.1016\/j.anai.2016.03.007_bib6","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1513\/pats.2306027","article-title":"Allergens, viruses, and asthma exacerbations","volume":"1","author":"Murray","year":"2004","journal-title":"Am Thorac Soc"},{"key":"10.1016\/j.anai.2016.03.007_bib7","doi-asserted-by":"crossref","first-page":"334","DOI":"10.2500\/aap.2006.27.2880","article-title":"Asthma prevalence in children living in north Mexico City and a comparison with other Latin American cities and world regions","volume":"27","author":"Del-Rio-Navarro","year":"2006","journal-title":"Allergy Asthma Proc"},{"key":"10.1016\/j.anai.2016.03.007_bib8","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.pharmthera.2014.12.005","article-title":"Virus-induced modulation of lower airway diseases: pathogenesis and pharmacologic approaches to treatment","volume":"148","author":"Leigh","year":"2015","journal-title":"Pharmacol Ther"},{"key":"10.1016\/j.anai.2016.03.007_bib9","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1136\/bmj.310.6989.1225","article-title":"Community study of role of viral infections in exacerbations of asthma in 9-11 year old children","volume":"310","author":"Johnston","year":"1995","journal-title":"BMJ"},{"key":"10.1016\/j.anai.2016.03.007_bib10","doi-asserted-by":"crossref","first-page":"982","DOI":"10.1136\/bmj.307.6910.982","article-title":"Respiratory viruses and exacerbations of asthma in adults","volume":"307","author":"Nicholson","year":"1993","journal-title":"BMJ"},{"key":"10.1016\/j.anai.2016.03.007_bib11","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1164\/ajrccm.154.3.8810601","article-title":"The relationship between upper respiratory infections and hospital admissions for asthma: a time-trend analysis","volume":"154","author":"Johnston","year":"1996","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.anai.2016.03.007_bib12","doi-asserted-by":"crossref","first-page":"e510","DOI":"10.1016\/j.ijid.2013.01.006","article-title":"Clinical characteristics and outcomes of influenza and other influenza-like illnesses in Mexico City","volume":"17","author":"Galindo-Fraga","year":"2013","journal-title":"Int J Infect Dis"},{"key":"10.1016\/j.anai.2016.03.007_bib13","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1164\/rccm.200801-060ST","article-title":"An official American Thoracic Society\/European Respiratory Society statement: asthma control and exacerbations: standardizing endpoints for clinical asthma trials and clinical practice","volume":"180","author":"Reddel","year":"2009","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.anai.2016.03.007_bib14","first-page":"21","article-title":"Viruses in asthma exacerbations","volume":"11","author":"Tan","year":"2005","journal-title":"Curr Opin Pulm Med"},{"key":"10.1016\/j.anai.2016.03.007_bib15","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.jcv.2007.10.028","article-title":"Enhanced severity of virus associated lower respiratory tract disease in asthma patients may not be associated with delayed viral clearance and increased viral load in upper respiratory tract","volume":"41","author":"van Elden","year":"2008","journal-title":"Clin Virol"},{"key":"10.1016\/j.anai.2016.03.007_bib16","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1016\/S0140-6736(02)07953-9","article-title":"Frequency, severity and duration of rhinovirus infections in asthmatic and non-asthmatic individuals: a longitudinal cohort study","volume":"359","author":"Corne","year":"2002","journal-title":"Lancet"},{"key":"10.1016\/j.anai.2016.03.007_bib17","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1136\/thx.2005.042523","article-title":"Study of modifiable risk factors for asthma exacerbations: virus infection and allergen exposure increase the risk of asthma hospital admissions in children","volume":"61","author":"Murray","year":"2006","journal-title":"Thorax"},{"key":"10.1016\/j.anai.2016.03.007_bib18","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1086\/511821","article-title":"Rhinovirus-associated hospitalizations in young children","volume":"195","author":"Miller","year":"2007","journal-title":"J\u00a0Infect Dis"},{"key":"10.1016\/j.anai.2016.03.007_bib19","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1016\/j.jaci.2006.08.041","article-title":"Prevalence of viral respiratory tract infections in children with asthma","volume":"119","author":"Khetsuriani","year":"2007","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.anai.2016.03.007_bib20","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.jcv.2009.06.007","article-title":"Human rhinovirus C associated with wheezing in hospitalised children in the Middle East","volume":"46","author":"Miller","year":"2009","journal-title":"J\u00a0Clin Virol"},{"key":"10.1016\/j.anai.2016.03.007_bib21","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1086\/605697","article-title":"Clinical and molecular epidemiology of human rhinovirus C in children and adults in Hong Kong reveals a possible distinct human rhinovirus C subgroup","volume":"200","author":"Lau","year":"2009","journal-title":"J\u00a0Infect Dis"},{"key":"10.1016\/j.anai.2016.03.007_bib22","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/j.jaci.2015.01.028","article-title":"The influence of asthma control on the severity of virus-induced asthma exacerbations","volume":"136","author":"Jackson","year":"2015","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.anai.2016.03.007_bib23","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1136\/bmjopen-2014-007435","article-title":"Multicentre observational study of adults with asthma exacerbations: who are the frequent users of the emergency department in Japan?","volume":"5","author":"Watase","year":"2015","journal-title":"BMJ Open"},{"key":"10.1016\/j.anai.2016.03.007_bib24","doi-asserted-by":"crossref","first-page":"276","DOI":"10.14423\/SMJ.0000000000000275","article-title":"Factors associated with emergency department visits in asthma exacerbation","volume":"108","author":"Wells","year":"2015","journal-title":"South Med J"},{"key":"10.1016\/j.anai.2016.03.007_bib25","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1016\/j.jaip.2015.05.003","article-title":"Children and adults with frequent hospitalizations for asthma exacerbation, 2012-2013: a multicenter observational study","volume":"3","author":"Hasegawa","year":"2015","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.anai.2016.03.007_bib26","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1136\/bmj.324.7340.763","article-title":"Synergism between allergens and viruses and risk of hospital admission with asthma: case-control study","volume":"324","author":"Green","year":"2002","journal-title":"BMJ"},{"key":"10.1016\/j.anai.2016.03.007_bib27","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1093\/infdis\/jiu224","article-title":"Influenza-like illness, the time to seek healthcare, and influenza antiviral receipt during the 2010-2011 influenza season-United States","volume":"210","author":"Biggerstaff","year":"2014","journal-title":"J\u00a0Infect Dis"},{"key":"10.1016\/j.anai.2016.03.007_bib28","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1111\/irv.12182","article-title":"Clinical diagnosis of pandemic A(H1N1)2009 influenza in children with negative rapid influenza diagnostic test by lymphopenia and lower C-reactive protein levels","volume":"8","author":"Wang","year":"2014","journal-title":"Influenza Other Respir Viruses"},{"key":"10.1016\/j.anai.2016.03.007_bib29","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1164\/ajrccm.158.4.9712082","article-title":"Asthma and natural colds: inflammatory indices in induced sputum: a feasibility study","volume":"158","author":"Pizzichini","year":"1998","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.anai.2016.03.007_bib30","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1136\/thx.2005.045187","article-title":"Asthma exacerbations 3: pathogenesis","volume":"61","author":"Wark","year":"2006","journal-title":"Thorax"},{"key":"10.1016\/j.anai.2016.03.007_bib31","doi-asserted-by":"crossref","first-page":"1439","DOI":"10.1513\/AnnalsATS.201406-270BC","article-title":"Body mass index and risk of hospitalization among adults presenting with asthma exacerbation to the emergency department","volume":"11","author":"Hasegawa","year":"2014","journal-title":"Ann Am Thorac Soc"},{"key":"10.1016\/j.anai.2016.03.007_bib32","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1016\/j.jaip.2015.03.017","article-title":"Prospective study on the relationship of obesity to asthma impairment and risk","volume":"3","author":"Schatz","year":"2015","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.anai.2016.03.007_bib33","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1016\/j.rmed.2005.08.001","article-title":"Higher BMI is associated with worse asthma control and quality of life but not asthma severity","volume":"100","author":"Lavoie","year":"2006","journal-title":"Respir Med"},{"key":"10.1016\/j.anai.2016.03.007_bib34","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/j.jaci.2008.06.024","article-title":"The relationship between obesity and asthma severity and control in adults","volume":"122","author":"Mosen","year":"2008","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.anai.2016.03.007_bib35","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1378\/chest.11-0027","article-title":"Obesity is a determinant of asthma control independent of inflammation and lung mechanics","volume":"140","author":"Farah","year":"2011","journal-title":"Chest"},{"key":"10.1016\/j.anai.2016.03.007_bib36","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1159\/000340038","article-title":"Overweight is associated with airflow obstruction and poor disease control but not with exhaled nitric oxide change in an asthmatic population","volume":"84","author":"Pisi","year":"2012","journal-title":"Respiration"},{"key":"10.1016\/j.anai.2016.03.007_bib37","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.jaci.2009.05.034","article-title":"Does higher body mass index contribute to worse asthma control in an urban population?","volume":"124","author":"Clerisme-Beaty","year":"2009","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.anai.2016.03.007_bib38","first-page":"551","article-title":"Increased body mass index does not lead to a worsening of asthma control in a large adult asthmatic population in Spain","volume":"20","author":"Sastre","year":"2010","journal-title":"J\u00a0Investig Allergol Clin Immunol"},{"key":"10.1016\/j.anai.2016.03.007_bib39","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1590\/S0104-42302013000600014","article-title":"Prevalence of obesity in asthma and its relations with asthma severity and control","volume":"59","author":"Forte","year":"2013","journal-title":"Rev Assoc Med Bras"},{"key":"10.1016\/j.anai.2016.03.007_bib40","first-page":"CD009339","article-title":"Weight loss interventions for chronic asthma","volume":"7","author":"Adeniyi","year":"2012","journal-title":"Cochrane Database Syst Rev"}],"container-title":["Annals of Allergy, Asthma & Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S108112061630045X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S108112061630045X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T13:14:30Z","timestamp":1761052470000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S108112061630045X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,5]]},"references-count":40,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2016,5]]}},"alternative-id":["S108112061630045X"],"URL":"https:\/\/doi.org\/10.1016\/j.anai.2016.03.007","relation":{},"ISSN":["1081-1206"],"issn-type":[{"value":"1081-1206","type":"print"}],"subject":[],"published":{"date-parts":[[2016,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Clinical characteristics of asthmatic patients with influenza-like illness and risk of severe exacerbations in Mexico","name":"articletitle","label":"Article Title"},{"value":"Annals of Allergy, Asthma & Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.anai.2016.03.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 American College of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}