{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T21:45:11Z","timestamp":1792619111278,"version":"4.5.0"},"reference-count":27,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2016,6,1]],"date-time":"2016-06-01T00:00:00Z","timestamp":1464739200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,6,1]],"date-time":"2016-06-01T00:00:00Z","timestamp":1464739200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["annallergy.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annals of Allergy, Asthma & Immunology"],"published-print":{"date-parts":[[2016,6]]},"DOI":"10.1016\/j.anai.2016.04.001","type":"journal-article","created":{"date-parts":[[2016,6,2]],"date-time":"2016-06-02T12:45:43Z","timestamp":1464871543000},"page":"554-558","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":23,"title":["Association between chronic idiopathic urticaria and hypertension"],"prefix":"10.1016","volume":"116","author":[{"given":"Heng-Wei","family":"Chang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui-Man","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hung-Rong","family":"Yen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chung Y.","family":"Hsu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Chen","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jen-Huai","family":"Chiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mao-Feng","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.anai.2016.04.001_bib1","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/S1081-1206(10)60360-2","article-title":"Effect of arterial hypertension on chronic urticaria duration","volume":"103","author":"Nebiolo","year":"2009","journal-title":"Ann Allergy Asthma Immunol"},{"key":"10.1016\/j.anai.2016.04.001_bib2","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/j.anai.2014.02.014","article-title":"Therapy of chronic urticaria: a simple, modern approach","volume":"112","author":"Kaplan","year":"2014","journal-title":"Ann Allergy Asthma Immunol"},{"key":"10.1016\/j.anai.2016.04.001_bib3","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1016\/j.coi.2008.09.005","article-title":"New concepts in chronic urticaria","volume":"20","author":"Vonakis","year":"2008","journal-title":"Curr Opin Immunol"},{"key":"10.1016\/j.anai.2016.04.001_bib4","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1016\/S0895-7061(00)00262-4","article-title":"Fibrinolytic\/hemostatic variables in arterial hypertension: response to treatment with irbesartan or atenolol","volume":"13","author":"Makris","year":"2000","journal-title":"Am J Hypertens"},{"key":"10.1016\/j.anai.2016.04.001_bib5","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1046\/j.1365-2222.2000.00857.x","article-title":"Warfarin treatment of chronic idiopathic urticaria and angio-oedema","volume":"30","author":"Parslew","year":"2000","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.anai.2016.04.001_bib6","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1111\/j.1365-2133.1992.tb00694.x","article-title":"Warfarin in the treatment of chronic urticaria\/angio-edema","volume":"126","author":"Barlow","year":"1992","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.anai.2016.04.001_bib7","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1111\/j.1398-9995.2009.02222.x","article-title":"Coagulation\/fibrinolysis and inflammation markers are associated with disease activity in patients with chronic urticaria","volume":"65","author":"Takahagi","year":"2010","journal-title":"Allergy"},{"key":"10.1016\/j.anai.2016.04.001_bib8","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1111\/j.1398-9995.2007.01514.x","article-title":"Severe chronic urticaria is associated with elevated plasma levels of D-dimer","volume":"63","author":"Asero","year":"2008","journal-title":"Allergy"},{"key":"10.1016\/j.anai.2016.04.001_bib9","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1016\/j.cyto.2015.04.016","article-title":"Pentraxin-3 as a local inflammatory marker in chronic spontaneous urticaria","volume":"76","author":"Kasperska-Zajac","year":"2015","journal-title":"Cytokine"},{"key":"10.1016\/j.anai.2016.04.001_bib10","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1038\/jhh.2013.111","article-title":"C-reactive protein and hypertension","volume":"28","author":"Hage","year":"2014","journal-title":"J\u00a0Hum Hypertens"},{"key":"10.1016\/j.anai.2016.04.001_bib11","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1093\/gerona\/glq030","article-title":"Plasma pentraxin 3, but not high-sensitivity C-reactive protein, is a useful inflammatory biomarker for predicting cognitive impairment in elderly hypertensive patients","volume":"65","author":"Yano","year":"2010","journal-title":"J\u00a0Gerontol A Biol Sci Med Sci"},{"key":"10.1016\/j.anai.2016.04.001_bib12","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1016\/S1081-1206(10)60266-9","article-title":"A\u00a0retrospective review of clinical presentation, thyroid autoimmunity, laboratory characteristics, and therapies used in patients with chronic idiopathic urticaria","volume":"103","author":"Najib","year":"2009","journal-title":"Ann Allergy Asthma Immunol"},{"key":"10.1016\/j.anai.2016.04.001_bib13","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1007\/s11882-008-0046-2","article-title":"Immunomodulatory approaches to the management of chronic urticaria: an immune-mediated inflammatory disease","volume":"8","author":"Bingham","year":"2008","journal-title":"Curr Allergy Asthma Rep"},{"key":"10.1016\/j.anai.2016.04.001_bib14","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/S1081-1206(10)61941-2","article-title":"Successful treatment of autoimmune chronic idiopathic urticaria with intravenous cyclophosphamide","volume":"89","author":"Bernstein","year":"2002","journal-title":"Ann Allergy Asthma Immunol"},{"key":"10.1016\/j.anai.2016.04.001_bib15","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1016\/0190-9622(91)70308-O","article-title":"Oral cyclosporine for severe chronic idiopathic urticaria and angioedema","volume":"25","author":"Fradin","year":"1991","journal-title":"J\u00a0Am Acad Dermatol"},{"key":"10.1016\/j.anai.2016.04.001_bib16","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1111\/j.1398-9995.1997.tb00996.x","article-title":"Low-dose cyclosporin A in the treatment of severe chronic idiopathic urticaria","volume":"52","author":"Toubi","year":"1997","journal-title":"Allergy"},{"key":"10.1016\/j.anai.2016.04.001_bib17","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1081\/IPH-100103860","article-title":"Cyclosporin A in patients affected by chronic idiopathic urticaria: a therapeutic alternative","volume":"23","author":"Loria","year":"2001","journal-title":"Immunopharmacol Immunotoxicol"},{"key":"10.1016\/j.anai.2016.04.001_bib18","first-page":"285","article-title":"Treatment of chronic idiopathic urticaria and positive autologous serum skin test with cyclosporine: clinical and immunological evaluation","volume":"24","author":"Di Gioacchino","year":"2003","journal-title":"Allergy Asthma Proc"},{"key":"10.1016\/j.anai.2016.04.001_bib19","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1046\/j.1365-2133.2000.03664.x","article-title":"Randomized double-blind study of cyclosporine in chronic \u2018idiopathic\u2019 urticaria","volume":"143","author":"Grattan","year":"2000","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.anai.2016.04.001_bib20","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1016\/j.jaci.2012.01.043","article-title":"Chronic urticaria and autoimmunity: associations found in a large population study","volume":"129","author":"Confino-Cohen","year":"2012","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.anai.2016.04.001_bib21","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1007\/s11906-014-0424-1","article-title":"Autoimmunity: an underlying factor in the pathogenesis of hypertension","volume":"16","author":"Mathis","year":"2014","journal-title":"Curr Hypertens Rep"},{"key":"10.1016\/j.anai.2016.04.001_bib22","doi-asserted-by":"crossref","first-page":"1286","DOI":"10.1093\/rheumatology\/ken159","article-title":"Hypertension in rheumatoid arthritis","volume":"47","author":"Panoulas","year":"2008","journal-title":"Rheumatology (Oxford)"},{"key":"10.1016\/j.anai.2016.04.001_bib23","first-page":"493","article-title":"Cardiovascular risk factor screening in systemic lupus erythematosus","volume":"30","author":"Al-Herz","year":"2003","journal-title":"J\u00a0Rheumatol"},{"key":"10.1016\/j.anai.2016.04.001_bib24","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1007\/s12026-014-8548-6","article-title":"The immune system and hypertension","volume":"59","author":"Singh","year":"2014","journal-title":"Immunol Res"},{"key":"10.1016\/j.anai.2016.04.001_bib25","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1016\/j.immuni.2014.11.007","article-title":"Hypertension: an immune disorder?","volume":"41","author":"Tracey","year":"2014","journal-title":"Immunity"},{"key":"10.1016\/j.anai.2016.04.001_bib26","doi-asserted-by":"crossref","first-page":"4642","DOI":"10.1172\/JCI74084","article-title":"DC isoketal-modified proteins activate T cells and promote hypertension","volume":"124","author":"Kirabo","year":"2014","journal-title":"J\u00a0Clin Invest"},{"key":"10.1016\/j.anai.2016.04.001_bib27","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1681\/ASN.2015050562","article-title":"Immune mechanisms in arterial hypertension","volume":"27","author":"Wenzel","year":"2016","journal-title":"J\u00a0Am Soc Nephrol"}],"container-title":["Annals of Allergy, Asthma & Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1081120616301259?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1081120616301259?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T13:14:30Z","timestamp":1761052470000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1081120616301259"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,6]]},"references-count":27,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2016,6]]}},"alternative-id":["S1081120616301259"],"URL":"https:\/\/doi.org\/10.1016\/j.anai.2016.04.001","relation":{},"ISSN":["1081-1206"],"issn-type":[{"value":"1081-1206","type":"print"}],"subject":[],"published":{"date-parts":[[2016,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Association between chronic idiopathic urticaria and hypertension","name":"articletitle","label":"Article Title"},{"value":"Annals of Allergy, Asthma & Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.anai.2016.04.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 American College of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}