{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T00:03:14Z","timestamp":1784332994004,"version":"3.55.0"},"reference-count":44,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2016,6,1]],"date-time":"2016-06-01T00:00:00Z","timestamp":1464739200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,6,1]],"date-time":"2016-06-01T00:00:00Z","timestamp":1464739200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["annallergy.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annals of Allergy, Asthma & Immunology"],"published-print":{"date-parts":[[2016,6]]},"DOI":"10.1016\/j.anai.2016.04.002","type":"journal-article","created":{"date-parts":[[2016,5,4]],"date-time":"2016-05-04T02:16:18Z","timestamp":1462328178000},"page":"497-505","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":33,"title":["Effect of acupuncture on house dust mite specific IgE, substance P,\u00a0and\u00a0symptoms in persistent allergic rhinitis"],"prefix":"10.1016","volume":"116","author":[{"given":"John Leslie","family":"McDonald","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter K.","family":"Smith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline A.","family":"Smith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlie","family":"Changli Xue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brenda","family":"Golianu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allan W.","family":"Cripps","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2 suppl 2","key":"10.1016\/j.anai.2016.04.002_bib1","doi-asserted-by":"crossref","first-page":"S103","DOI":"10.1016\/j.jaci.2009.12.989","article-title":"Rhinitis and sinusitis","volume":"125","author":"Dykewicz","year":"2010","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.anai.2016.04.002_bib2","doi-asserted-by":"crossref","first-page":"57","DOI":"10.2500\/ajra.2015.29.4116","article-title":"Acupuncture for the treatment of allergic rhinitis: a systematic review and meta-analysis","volume":"29","author":"Feng","year":"2015","journal-title":"Am J Rhinol Allergy"},{"key":"10.1016\/j.anai.2016.04.002_bib3","first-page":"136","article-title":"Effects of electroacupuncture on plasma vasoactive intestinal peptide and substance P in perennial allergic rhinitis patients [in Chinese]","volume":"32","author":"Li","year":"2007","journal-title":"Acupunct Res"},{"key":"10.1016\/j.anai.2016.04.002_bib4","doi-asserted-by":"crossref","first-page":"591796","DOI":"10.1155\/2013\/591796","article-title":"The anti-inflammatory effects of acupuncture and their relevance to allergic rhinitis: a narrative review and proposed model","volume":"2013","author":"McDonald","year":"2013","journal-title":"Evid Based Complement Alternat Med"},{"key":"10.1016\/j.anai.2016.04.002_bib5","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.jim.2005.09.010","article-title":"Impact of saliva collection methods on sIgA and cortisol assays and acceptability to participants","volume":"307","author":"Strazdins","year":"2005","journal-title":"J\u00a0Immunol Methods"},{"key":"10.1016\/j.anai.2016.04.002_bib6","first-page":"151","article-title":"Committee report on standardization of rhinomanometry","volume":"22","author":"Clement","year":"1984","journal-title":"Rhinology"},{"key":"10.1016\/j.anai.2016.04.002_bib7","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/2045-7022-1-2","article-title":"Diagnostic tools in rhinology: EAACI position paper","volume":"1","author":"Scadding","year":"2011","journal-title":"Clin Transl Allergy"},{"key":"10.1016\/j.anai.2016.04.002_bib8","first-page":"104","article-title":"Study on cytokines IL-2, IL-6, IL-10 in patients of chronic allergic rhinitis treated with acupuncture","volume":"22","author":"Petti","year":"2002","journal-title":"J\u00a0Tradit Chin Med"},{"key":"10.1016\/j.anai.2016.04.002_bib9","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1142\/S0192415X0200020X","article-title":"Effect of acupuncture in the treatment of seasonal allergic rhinitis: a randomized controlled clinical trial","volume":"30","author":"Xue","year":"2002","journal-title":"Am J Chin Med"},{"key":"10.1016\/j.anai.2016.04.002_bib10","doi-asserted-by":"crossref","first-page":"337","DOI":"10.5694\/j.1326-5377.2007.tb01275.x","article-title":"Acupuncture for persistent allergic rhinitis: a randomised, sham-controlled trial","volume":"187","author":"Xue","year":"2007","journal-title":"Med J Aust"},{"key":"10.1016\/j.anai.2016.04.002_bib11","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1111\/j.1398-9995.2004.00540.x","article-title":"Acupuncture and Chinese herbal medicine in the treatment of patients with seasonal allergic rhinitis: a randomized-controlled clinical trial","volume":"59","author":"Brinkhaus","year":"2004","journal-title":"Allergy"},{"key":"10.1016\/j.anai.2016.04.002_bib12","doi-asserted-by":"crossref","first-page":"1242","DOI":"10.1542\/peds.2004-0744","article-title":"A\u00a0double-blind, randomized, placebo-controlled trial of acupuncture for the treatment of childhood persistent allergic rhinitis","volume":"114","author":"Ng","year":"2004","journal-title":"Pediatrics"},{"key":"10.1016\/j.anai.2016.04.002_bib13","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1142\/S0192415X04001813","article-title":"The effect of acupuncture on allergic rhinitis: a randomized controlled clinical trial","volume":"32","author":"Magnusson","year":"2004","journal-title":"Am J Chin Med"},{"key":"10.1016\/j.anai.2016.04.002_bib14","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/S0965-2299(98)80080-0","article-title":"The credibility of placebo controls in acupuncture studies","volume":"6","author":"Wood","year":"1998","journal-title":"Complement Ther Med"},{"key":"10.1016\/j.anai.2016.04.002_bib15","series-title":"Essentials of Chinese Acupuncture","author":"Beijing College of Traditional Chinese Medicine","year":"1980"},{"key":"10.1016\/j.anai.2016.04.002_bib16","series-title":"Acupuncture: A Comprehensive Text","year":"1981"},{"key":"10.1016\/j.anai.2016.04.002_bib17","series-title":"Acupuncture and Moxibustion Meridians and Points","author":"Choe","year":"1973"},{"key":"10.1016\/j.anai.2016.04.002_bib18","series-title":"Chinese Acupuncture","author":"Chuang","year":"1972"},{"key":"10.1016\/j.anai.2016.04.002_bib19","series-title":"Traite de Medecine Chinoise (Tome 1) [in French]","author":"Chamfrault","year":"1964"},{"key":"10.1016\/j.anai.2016.04.002_bib20","series-title":"Fundamentals of Chinese Acupuncture","author":"Ellis","year":"1988"},{"key":"10.1016\/j.anai.2016.04.002_bib21","series-title":"Chinese Acupuncture and Moxibustion","year":"1987"},{"key":"10.1016\/j.anai.2016.04.002_bib22","series-title":"Acupuncture Medicine: Its Historical and Clinical Background","author":"Omura","year":"1982"},{"key":"10.1016\/j.anai.2016.04.002_bib23","doi-asserted-by":"crossref","first-page":"515","DOI":"10.3748\/wjg.v5.i6.515","article-title":"Study of the mechanisms of acupuncture and moxibustion treatment for ulcerative colitis rats in view of the gene expression of cytokines","volume":"5","author":"Wu","year":"1999","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.anai.2016.04.002_bib24","series-title":"WHO International Standard Acupuncture Point Locations in the Western Pacific Region Manila","author":"World Health Organization","year":"2008"},{"key":"10.1016\/j.anai.2016.04.002_bib25","first-page":"353","article-title":"A\u00a0clinical study on allergic rhinitis [in Korean]","volume":"19","author":"Kim","year":"1998","journal-title":"Kor Int Med Soc"},{"key":"10.1016\/j.anai.2016.04.002_bib26","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1142\/S0192415X7500027X","article-title":"Effect of acupuncture on allergic rhinitis: clinical and laboratory evaluations","volume":"3","author":"Lau","year":"1975","journal-title":"Am J Chin Med"},{"key":"10.1016\/j.anai.2016.04.002_bib27","first-page":"557","article-title":"Therapeutic effect of acupuncture on allergic rhinitis and its effects on immunologic function [in Chinese]","volume":"26","author":"Rao","year":"2006","journal-title":"Zhongguo Zhen Jiu"},{"key":"10.1016\/j.anai.2016.04.002_bib28","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1006\/nimg.2002.1145","article-title":"Neuronal specificity of acupuncture response: a fMRI study with electroacupuncture","volume":"16","author":"Wu","year":"2002","journal-title":"Neuroimage"},{"key":"10.1016\/j.anai.2016.04.002_bib29","first-page":"981","article-title":"Study on the effects of acupuncture at acupoint and non-acupoint on functional connectivity of different brain regions with functional magnetic resonance imaging [in Chinese]","volume":"29","author":"Liu","year":"2009","journal-title":"Zhongguo Zhen Jiu"},{"key":"10.1016\/j.anai.2016.04.002_bib30","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/S0965-2299(03)00124-9","article-title":"Sham interventions in randomized clinical trials of acupuncture: a review","volume":"11","author":"Dincer","year":"2003","journal-title":"Complement Ther Med"},{"key":"10.1016\/j.anai.2016.04.002_bib31","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1089\/acm.2006.12.303","article-title":"A\u00a0review and analysis of placebo treatments, placebo effects, and placebo controls in trials of medical procedures when sham is not inert","volume":"12","author":"Birch","year":"2006","journal-title":"J\u00a0Altern Complement Med"},{"key":"10.1016\/j.anai.2016.04.002_bib32","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/S1380-2933(97)10005-7","article-title":"The TH1\/TH2 paradigm in allergy","volume":"3","author":"Maggi","year":"1998","journal-title":"Immunotechnology"},{"key":"10.1016\/j.anai.2016.04.002_bib33","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1111\/j.1398-9995.2009.01937.x","article-title":"TRPV1-mediated itch in seasonal allergic rhinitis","volume":"64","author":"Alenmyr","year":"2009","journal-title":"Allergy"},{"key":"10.1016\/j.anai.2016.04.002_bib34","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1016\/0091-6749(92)90155-U","article-title":"Mediators of allergic rhinitis","volume":"90","author":"White","year":"1992","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.anai.2016.04.002_bib35","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1097\/MOO.0b013e328259c372","article-title":"Neural aspects of allergic rhinitis","volume":"15","author":"Kim","year":"2007","journal-title":"Curr Opin Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.anai.2016.04.002_bib36","doi-asserted-by":"crossref","first-page":"975632","DOI":"10.1155\/2015\/975632","article-title":"Mediators, receptors, and signalling pathways in the anti-inflammatory and antihyperalgesic effects of acupuncture","volume":"2015","author":"McDonald","year":"2015","journal-title":"Evid Based Complement Altern Med"},{"key":"10.1016\/j.anai.2016.04.002_bib37","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/j.aller.2012.05.010","article-title":"Assessment of nasal obstruction: correlation between subjective and objective techniques","volume":"41","author":"Yepes-Nunez","year":"2013","journal-title":"Allergol Immunopathol (Madr)"},{"key":"10.1016\/j.anai.2016.04.002_bib38","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1513\/pats.201006-042RN","article-title":"Subjective nasal fullness and objective congestion","volume":"8","author":"Baraniuk","year":"2011","journal-title":"Proc Am Thorac Soc"},{"issue":"3 suppl 1","key":"10.1016\/j.anai.2016.04.002_bib39","doi-asserted-by":"crossref","first-page":"S442","DOI":"10.1016\/j.jaci.2004.12.015","article-title":"Objective monitoring of nasal patency and nasal physiology in rhinitis","volume":"115","author":"Nathan","year":"2005","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.anai.2016.04.002_bib40","doi-asserted-by":"crossref","first-page":"160","DOI":"10.4193\/Rhino14.048","article-title":"Are measurements of peak nasal flow useful for evaluating nasal obstruction in patients with allergic rhinitis?","volume":"53","author":"Martins de Oliveira","year":"2015","journal-title":"Rhinology"},{"key":"10.1016\/j.anai.2016.04.002_bib41","first-page":"229","article-title":"Effect of acupuncture on nasal obstruction in patients with persistent allergic rhinitis: a randomized, controlled trial","volume":"22","author":"Park","year":"2005","journal-title":"J\u00a0Korean Acupunct Moxibustion"},{"key":"10.1016\/j.anai.2016.04.002_bib42","doi-asserted-by":"crossref","first-page":"225","DOI":"10.7326\/0003-4819-158-4-201302190-00002","article-title":"Acupuncture in patients with seasonal allergic rhinitis: a randomized trial","volume":"158","author":"Brinkhaus","year":"2013","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.anai.2016.04.002_bib43","series-title":"Australian Health Survey (2011-2012)","author":"Australian Bureau of Statistics","year":"2013"},{"key":"10.1016\/j.anai.2016.04.002_bib44","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1513\/pats.200906-052DP","article-title":"United airways concept: what does it teach us about systemic inflammation in airways disease?","volume":"6","author":"Braunstahl","year":"2009","journal-title":"Proc Am Thorac Soc"}],"container-title":["Annals of Allergy, Asthma & Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1081120616301260?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1081120616301260?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T13:14:07Z","timestamp":1761052447000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1081120616301260"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,6]]},"references-count":44,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2016,6]]}},"alternative-id":["S1081120616301260"],"URL":"https:\/\/doi.org\/10.1016\/j.anai.2016.04.002","relation":{},"ISSN":["1081-1206"],"issn-type":[{"value":"1081-1206","type":"print"}],"subject":[],"published":{"date-parts":[[2016,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effect of acupuncture on house dust mite specific IgE, substance P,\u00a0and\u00a0symptoms in persistent allergic rhinitis","name":"articletitle","label":"Article Title"},{"value":"Annals of Allergy, Asthma & Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.anai.2016.04.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 American College of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}