{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,14]],"date-time":"2026-03-14T05:24:31Z","timestamp":1773465871605,"version":"3.50.1"},"reference-count":21,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2016,6,1]],"date-time":"2016-06-01T00:00:00Z","timestamp":1464739200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,6,1]],"date-time":"2016-06-01T00:00:00Z","timestamp":1464739200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["annallergy.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annals of Allergy, Asthma & Immunology"],"published-print":{"date-parts":[[2016,6]]},"DOI":"10.1016\/j.anai.2016.04.004","type":"journal-article","created":{"date-parts":[[2016,5,4]],"date-time":"2016-05-04T02:17:55Z","timestamp":1462328275000},"page":"559-564","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["Effect of eosinophils activated with Alternaria on the production of extracellular matrix from nasal fibroblasts"],"prefix":"10.1016","volume":"116","author":[{"given":"Seung-Heon","family":"Shin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mi-Kyung","family":"Ye","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sung-Yong","family":"Choi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yee-Hyuk","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.anai.2016.04.004_bib1","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1007\/s11882-001-0017-3","article-title":"The molecular biology of nasal polyposis","volume":"1","author":"Bernstein","year":"2001","journal-title":"Curr Allergy Asthma Rep"},{"key":"10.1016\/j.anai.2016.04.004_bib2","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1159\/000337460","article-title":"Role of reactive oxygen species in transforming growth factor beta1-induced alpha smooth muscle actin and collagen production in nasal polyp-derived fibroblasts","volume":"159","author":"Park","year":"2012","journal-title":"Int Arch Allergy Immunol"},{"key":"10.1016\/j.anai.2016.04.004_bib3","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1111\/j.1365-2222.2011.03931.x","article-title":"Epigenetic regulation of myofibroblast differentiation and extracellular matrix production in nasal polyp-derived fibroblasts","volume":"42","author":"Cho","year":"2012","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.anai.2016.04.004_bib4","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/S1081-1206(10)60087-7","article-title":"Effect of extracellular matrix composition on airway epithelial cell and fibroblast structure: implications for airway remodeling in asthma","volume":"102","author":"Royce","year":"2009","journal-title":"Ann Allergy Asthma Immunol"},{"key":"10.1016\/j.anai.2016.04.004_bib5","doi-asserted-by":"crossref","first-page":"3882","DOI":"10.1182\/blood-2012-06-330845","article-title":"The expanding role(s) of eosinophils in health and disease","volume":"120","author":"Jacobsen","year":"2012","journal-title":"Blood"},{"key":"10.1016\/j.anai.2016.04.004_bib6","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1007\/s11882-007-0073-4","article-title":"Inflammatory mechanisms and remodeling in chronic rhinosinusitis and nasal polyps","volume":"7","author":"Pawankar","year":"2007","journal-title":"Curr Allergy Asthma Rep"},{"key":"10.1016\/j.anai.2016.04.004_bib7","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1159\/000301578","article-title":"Airborne fungi induce nasal polyp epithelial cell activation and toll-like receptor expression","volume":"153","author":"Shin","year":"2010","journal-title":"Int Arch Allergy Immunol"},{"key":"10.1016\/j.anai.2016.04.004_bib8","doi-asserted-by":"crossref","first-page":"5439","DOI":"10.4049\/jimmunol.175.8.5439","article-title":"Nonpathogenic, environmental fungi induce activation and degranulation of human eosinophils","volume":"175","author":"Inoue","year":"2005","journal-title":"J\u00a0Immunol"},{"key":"10.1016\/j.anai.2016.04.004_bib9","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1111\/j.1365-2222.2008.02959.x","article-title":"Heterogeneous response of nasal and lung fibroblasts to transforming growth factor-beta 1","volume":"38","author":"Nonaka","year":"2008","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.anai.2016.04.004_bib10","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4193\/Rhino12.000","article-title":"European position paper on rhinosinusitis and nasal polyps 2012: a summary for otorhinolaryngologists","volume":"50","author":"Fokkens","year":"2012","journal-title":"Rhinology"},{"key":"10.1016\/j.anai.2016.04.004_bib11","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.anl.2015.07.003","article-title":"Role of TLRs in the production of chemical mediators in nasal polyp fibroblasts","volume":"43","author":"Shin","year":"2016","journal-title":"Auris Nasus Larynx"},{"key":"10.1016\/j.anai.2016.04.004_bib12","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/0022-1759(91)90315-7","article-title":"An improved immunomagnetic procedure for the isolation of highly purified human blood eosinophils","volume":"145","author":"Hansel","year":"1991","journal-title":"J\u00a0Immunol Methods"},{"key":"10.1016\/j.anai.2016.04.004_bib13","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.anai.2013.06.023","article-title":"Expression of matrix metalloproteinase 2 and 9 and tissue inhibitor of metalloproteinase 1 in nonrecurrent vs recurrent nasal polyps","volume":"111","author":"Yeo","year":"2013","journal-title":"Ann Allergy Asthma Immunol"},{"key":"10.1016\/j.anai.2016.04.004_bib14","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/j.anai.2011.07.016","article-title":"Variations in expression of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in nasal mucosa of aspirin-sensitive versus aspirin-tolerant patients with nasal polyposis","volume":"107","author":"Mudd","year":"2011","journal-title":"Ann Allergy Asthma Immunol"},{"key":"10.1016\/j.anai.2016.04.004_bib15","doi-asserted-by":"crossref","first-page":"e90683","DOI":"10.1371\/journal.pone.0090683","article-title":"Lipopolysaccaride induced pro-inflammatory cytokines and MMP production via TLR4 in nasal polyp derived fibroblast and organ culture","volume":"12","author":"Cho","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.anai.2016.04.004_bib16","doi-asserted-by":"crossref","first-page":"6708","DOI":"10.4049\/jimmunol.0901220","article-title":"Recognition of fungal protease activities induces cellular activation and eosinophil-derived neurotoxin release in human eosinophils","volume":"183","author":"Matsuwaki","year":"2009","journal-title":"J\u00a0Immunol"},{"key":"10.1016\/j.anai.2016.04.004_bib17","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/j.coi.2007.07.021","article-title":"The role of eosinophils in airway tissue remodeling in asthma","volume":"19","author":"Kariyawasam","year":"2007","journal-title":"Curr Opin Immunol"},{"key":"10.1016\/j.anai.2016.04.004_bib18","doi-asserted-by":"crossref","first-page":"5912","DOI":"10.4049\/jimmunol.169.10.5912","article-title":"Selective eosinophil adhesion to fibroblast via IFN-\u03b3-induced galectin-9","volume":"169","author":"Asakura","year":"2002","journal-title":"J\u00a0Immunol"},{"key":"10.1016\/j.anai.2016.04.004_bib19","doi-asserted-by":"crossref","first-page":"2907","DOI":"10.4049\/jimmunol.181.4.2907","article-title":"Innate antifungal immunity of human eosinophils mediated by a \u03b22-integrin, CD11b","volume":"181","author":"Yoon","year":"2008","journal-title":"J\u00a0Immunol"},{"key":"10.1016\/j.anai.2016.04.004_bib20","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1016\/j.jaci.2005.06.031","article-title":"Eosinophil-fibroblast interactions induce fibroblast IL-6 secretion and extracellular matrix gene expression: implications in fibrogenesis","volume":"116","author":"Gomes","year":"2005","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.anai.2016.04.004_bib21","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1128\/CMR.16.4.637-646.2003","article-title":"Role of toll-like receptors in pathogen recognition","volume":"16","author":"Janssens","year":"2003","journal-title":"Clin Microbiol Rev"}],"container-title":["Annals of Allergy, Asthma & Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1081120616301284?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1081120616301284?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T13:14:33Z","timestamp":1761052473000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1081120616301284"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,6]]},"references-count":21,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2016,6]]}},"alternative-id":["S1081120616301284"],"URL":"https:\/\/doi.org\/10.1016\/j.anai.2016.04.004","relation":{},"ISSN":["1081-1206"],"issn-type":[{"value":"1081-1206","type":"print"}],"subject":[],"published":{"date-parts":[[2016,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effect of eosinophils activated with Alternaria on the production of extracellular matrix from nasal fibroblasts","name":"articletitle","label":"Article Title"},{"value":"Annals of Allergy, Asthma & Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.anai.2016.04.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 American College of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}