{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T01:48:26Z","timestamp":1790214506668,"version":"4.1.0"},"reference-count":26,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2016,7,1]],"date-time":"2016-07-01T00:00:00Z","timestamp":1467331200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,7,1]],"date-time":"2016-07-01T00:00:00Z","timestamp":1467331200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["annallergy.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annals of Allergy, Asthma & Immunology"],"published-print":{"date-parts":[[2016,7]]},"DOI":"10.1016\/j.anai.2016.04.021","type":"journal-article","created":{"date-parts":[[2016,5,21]],"date-time":"2016-05-21T03:10:14Z","timestamp":1463800214000},"page":"67-71","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":119,"title":["Penicillin skin testing in hospitalized patients with \u03b2-lactam allergies"],"prefix":"10.1016","volume":"117","author":[{"given":"Esther A.","family":"King","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sridevi","family":"Challa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Curtin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonard","family":"Bielory","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.anai.2016.04.021_bib1","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1016\/j.jaci.2013.09.021","article-title":"Health care use and serious infection prevalence associated with penicillin \u201callergy\u201d in hospitalized patients: a cohort study","volume":"133","author":"Macy","year":"2014","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.anai.2016.04.021_bib2","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/j.jaip.2013.01.006","article-title":"Treatment of patients with a history of penicillin allergy in a large tertiary-care academic hospital","volume":"1","author":"Picard","year":"2013","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.anai.2016.04.021_bib3","doi-asserted-by":"crossref","first-page":"489","DOI":"10.2500\/aap.2014.35.3791","article-title":"Prevalence and characteristics of reported penicillin allergy in an urban outpatient adult population","volume":"35","author":"Albin","year":"2014","journal-title":"Allergy Asthma Proc"},{"key":"10.1016\/j.anai.2016.04.021_bib4","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1046\/j.1365-2222.2003.01638.x","article-title":"The economic burden of antibiotic treatment of penicillin-allergic patients in internal medicine wards of a general tertiary care hospital","volume":"33","author":"Sade","year":"2003","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.anai.2016.04.021_bib5","doi-asserted-by":"crossref","first-page":"2819","DOI":"10.1001\/archinte.160.18.2819","article-title":"The incidence of antimicrobial allergies in hospitalized patients: implication regarding prescribing patterns and emerging bacterial resistance","volume":"18","author":"Lee","year":"2000","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.anai.2016.04.021_bib6","doi-asserted-by":"crossref","first-page":"AB170","DOI":"10.1016\/j.jaci.2012.12.1269","article-title":"Drug resistant infections with methicillin-resistant Staphylococcus aureus, Clostridium difficile, and vancomycin resistant Enterococcus are associated with a higher prevalence of penicillin allergy [abstract]","volume":"131","author":"Reddy","year":"2013","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.anai.2016.04.021_bib7","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.jaip.2013.02.002","article-title":"Safely diagnosing clinically significant penicillin allergy using only penicilloyl-poly-lysine, penicillin, and oral amoxicillin","volume":"1","author":"Macy","year":"2013","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.anai.2016.04.021_bib8","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1002\/phar.1288","article-title":"Penicillin skin testing: potential implications for antimicrobial stewardship","volume":"33","author":"Unger","year":"2013","journal-title":"Pharmacotherapy"},{"key":"10.1016\/j.anai.2016.04.021_bib9","series-title":"ATC Index with DDDs","author":"World Health Organization, Collaborating Centre for Drug Statistics Methodology","year":"2004"},{"key":"10.1016\/j.anai.2016.04.021_bib10","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/j.anai.2010.08.002","article-title":"Drug allergy: an updated practice parameter","volume":"105","author":"Joint Task Force on Practice Parameters; American Academy of Allergy, Asthma and Immunology; American College of Allergy, Asthma, and Immunology; Joint Council of Allergy, Asthma and Immunology","year":"2010","journal-title":"Ann Allergy Asthma Immunol"},{"key":"10.1016\/j.anai.2016.04.021_bib11","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/0091-6749(77)90064-1","article-title":"Evaluation of penicillin hypersensitivity: value of clinical history and skin testing with penicilloyl-polylysine and penicillin G: a cooperative prospective study of the penicillin study group of the American Academy of Allergy","volume":"60","author":"Green","year":"1977","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.anai.2016.04.021_bib12","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/S1081-1206(10)60882-4","article-title":"Penicillin skin testing in patients with a history of \u03b2-lactam allergy","volume":"98","author":"del Real","year":"2007","journal-title":"Ann Allergy Asthma Immunol"},{"key":"10.1016\/j.anai.2016.04.021_bib13","first-page":"20","article-title":"Routine penicillin skin testing in hospitalized patients with a history of penicillin allergy","volume":"8","author":"Macy","year":"2004","journal-title":"Perm J"},{"key":"10.1016\/j.anai.2016.04.021_bib14","doi-asserted-by":"crossref","first-page":"1685","DOI":"10.1086\/320752","article-title":"Introduction of a practice guideline for penicillin skin testing improves the appropriateness of antibiotic therapy","volume":"32","author":"Forrest","year":"2001","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.anai.2016.04.021_bib15","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1592\/phco.31.8.742","article-title":"Impact of an antimicrobial allergy label in the medical record on clinical outcomes in hospitalized patients","volume":"31","author":"Charneski","year":"2011","journal-title":"Pharmacotherapy"},{"key":"10.1016\/j.anai.2016.04.021_bib16","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1186\/1471-2334-11-279","article-title":"Comparative effectiveness of nafcillin or cefazolin versus vancomycin in methicillin-susceptible Staphylococcus aureus bacteremia","volume":"11","author":"Schweizer","year":"2011","journal-title":"BMC Infect Dis"},{"key":"10.1016\/j.anai.2016.04.021_bib17","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1086\/510386","article-title":"Use of vancomycin or first-generation cephalosporins for the treatment of hemodialysis-dependent patients with methicillin-susceptible Staphylococcus aureus bacteremia","volume":"44","author":"Stryjewski","year":"2007","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.anai.2016.04.021_bib18","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1093\/cid\/civ308","article-title":"Comparative effectiveness of \u03b2-lactams versus vancomycin for treatment of methicillin-susceptible Staphylococcus aureus bloodstream infections among 122 hospitals","volume":"61","author":"McDanel","year":"2015","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.anai.2016.04.021_bib19","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.1161\/CIR.0000000000000296","article-title":"Infective endocarditis in adults: diagnosis, antimicrobial therapy, and management of complications: a scientific statement for healthcare professionals from the American Heart Association","volume":"132","author":"Baddour","year":"2015","journal-title":"Circulation"},{"key":"10.1016\/j.anai.2016.04.021_bib20","doi-asserted-by":"crossref","first-page":"2835","DOI":"10.1056\/NEJMc053529","article-title":"Imipenem in patients with immediate hypersensitivity to penicillins","volume":"354","author":"Romano","year":"2006","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.anai.2016.04.021_bib21","doi-asserted-by":"crossref","first-page":"266","DOI":"10.7326\/0003-4819-146-4-200702200-00005","article-title":"Brief communication: tolerability of meropenem in patients with IgE-mediated hypersensitivity to penicillins","volume":"146","author":"Romano","year":"2007","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.anai.2016.04.021_bib22","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1111\/j.1398-9995.2007.01532.x","article-title":"Tolerability of meropenem in children with IgE-mediated hypersensitivity to penicillins","volume":"63","author":"Atanaskovic-Markovi\u0107","year":"2008","journal-title":"Allergy"},{"key":"10.1016\/j.anai.2016.04.021_bib23","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1016\/j.jaip.2015.05.033","article-title":"Minor determinants are essential for optimal penicillin allergy testing: a pro\/con debate","volume":"3","author":"Solensky","year":"2015","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.anai.2016.04.021_bib24","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1001\/archinte.1992.00400170105020","article-title":"Results of the National Institute of Allergy and Infectious Diseases Collaborative Clinical Trial to test the predictive value of skin testing with major and minor penicillin derivatives in hospitalized adults","volume":"152","author":"Sogn","year":"1992","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.anai.2016.04.021_bib25","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.jaci.2010.08.025","article-title":"The role of penicillin in benign skin rashes in childhood: a prospective study based on drug rechallenge","volume":"127","author":"Caubet","year":"2011","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.anai.2016.04.021_bib26","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1093\/ajhp\/61.12.1271","article-title":"Pharmacist-managed service providing penicillin allergy skin tests","volume":"61","author":"Wall","year":"2004","journal-title":"Am J Health Syst Pharm"}],"container-title":["Annals of Allergy, Asthma & Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S108112061630179X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S108112061630179X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T13:14:18Z","timestamp":1761052458000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S108112061630179X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,7]]},"references-count":26,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,7]]}},"alternative-id":["S108112061630179X"],"URL":"https:\/\/doi.org\/10.1016\/j.anai.2016.04.021","relation":{},"ISSN":["1081-1206"],"issn-type":[{"value":"1081-1206","type":"print"}],"subject":[],"published":{"date-parts":[[2016,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Penicillin skin testing in hospitalized patients with \u03b2-lactam allergies","name":"articletitle","label":"Article Title"},{"value":"Annals of Allergy, Asthma & Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.anai.2016.04.021","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 American College of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}