{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T07:59:58Z","timestamp":1783065598217,"version":"3.54.6"},"reference-count":33,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2016,10,1]],"date-time":"2016-10-01T00:00:00Z","timestamp":1475280000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,10,1]],"date-time":"2016-10-01T00:00:00Z","timestamp":1475280000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["annallergy.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annals of Allergy, Asthma & Immunology"],"published-print":{"date-parts":[[2016,10]]},"DOI":"10.1016\/j.anai.2016.08.008","type":"journal-article","created":{"date-parts":[[2016,9,9]],"date-time":"2016-09-09T15:14:13Z","timestamp":1473434053000},"page":"387-393.e2","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"title":["Role of food and aeroallergen sensitization in eosinophilic esophagitis in adults"],"prefix":"10.1016","volume":"117","author":[{"given":"Ashleigh A.","family":"Olson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael D.","family":"Evans","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mats W.","family":"Johansson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chloe H.","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David M.","family":"Manthei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric A.","family":"Gaumnitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sameer K.","family":"Mathur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.anai.2016.08.008_bib1","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.iac.2014.09.007","article-title":"Eosinophilic esophagitis","volume":"35","author":"Aceves","year":"2015","journal-title":"Immunol Allergy Clin North Am"},{"key":"10.1016\/j.anai.2016.08.008_bib2","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1111\/j.1398-9995.2012.02787.x","article-title":"Pediatric and adult eosinophilic esophagitis: similarities and differences","volume":"67","author":"Straumann","year":"2012","journal-title":"Allergy"},{"key":"10.1016\/j.anai.2016.08.008_bib3","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1016\/0016-5085(95)90637-1","article-title":"Eosinophilic esophagitis attributed to gastroesophageal reflux: improvement with an amino acid-based formula","volume":"109","author":"Kelly","year":"1995","journal-title":"Gastroenterology"},{"key":"10.1016\/j.anai.2016.08.008_bib4","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/j.jaci.2012.05.021","article-title":"Identification of causative foods in children with eosinophilic esophagitis treated with an elimination diet","volume":"130","author":"Spergel","year":"2012","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.anai.2016.08.008_bib5","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1016\/j.cgh.2013.09.007","article-title":"Food allergy testing in eosinophilic esophagitis: what the gastroenterologist needs to know","volume":"12","author":"Aceves","year":"2014","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.anai.2016.08.008_bib6","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1111\/j.1572-0241.2003.07390.x","article-title":"Elemental diet is an effective treatment for eosinophilic esophagitis in children and adolescents","volume":"98","author":"Markowitz","year":"2003","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.anai.2016.08.008_bib7","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1038\/ajg.2012.468","article-title":"Elemental diet induces histologic response in adult eosinophilic esophagitis","volume":"108","author":"Peterson","year":"2013","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.anai.2016.08.008_bib8","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1111\/all.12420","article-title":"Efficacy of IgE-targeted vs empiric six-food elimination diets for adult eosinophilic oesophagitis","volume":"69","author":"Rodriguez-Sanchez","year":"2014","journal-title":"Allergy"},{"key":"10.1016\/j.anai.2016.08.008_bib9","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1016\/j.jaci.2014.07.023","article-title":"Four-food group elimination diet for adult eosinophilic esophagitis: a prospective multicenter study","volume":"134","author":"Molina-Infante","year":"2014","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.anai.2016.08.008_bib10","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1016\/j.cgh.2006.05.026","article-title":"Effect of six-food elimination diet on clinical and histologic outcomes in eosinophilic esophagitis","volume":"4","author":"Kagalwalla","year":"2006","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.anai.2016.08.008_bib11","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1016\/j.jaci.2012.06.027","article-title":"Selective elimination diet based on skin testing has suboptimal efficacy for adult eosinophilic esophagitis","volume":"130","author":"Molina-Infante","year":"2012","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.anai.2016.08.008_bib12","doi-asserted-by":"crossref","first-page":"1451","DOI":"10.1053\/j.gastro.2012.03.001","article-title":"Elimination diet effectively treats eosinophilic esophagitis in adults; food reintroduction identifies causative factors","volume":"142","author":"Gonsalves","year":"2012","journal-title":"Gastroenterology"},{"key":"10.1016\/j.anai.2016.08.008_bib13","doi-asserted-by":"crossref","first-page":"1639","DOI":"10.1053\/j.gastro.2014.02.006","article-title":"Efficacy of dietary interventions for inducing histologic remission in patients with eosinophilic esophagitis: a systematic review and meta-analysis","volume":"146","author":"Arias","year":"2014","journal-title":"Gastroenterology"},{"key":"10.1016\/j.anai.2016.08.008_bib14","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1053\/j.gastro.2014.08.028","article-title":"Development and validation of a symptom-based activity index for adults with eosinophilic esophagitis","volume":"147","author":"Schoepfer","year":"2014","journal-title":"Gastroenterology"},{"key":"10.1016\/j.anai.2016.08.008_bib15","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1136\/gutjnl-2011-301817","article-title":"Endoscopic assessment of the oesophageal features of eosinophilic oesophagitis: validation of a novel classification and grading system","volume":"62","author":"Hirano","year":"2013","journal-title":"Gut"},{"key":"10.1016\/j.anai.2016.08.008_bib16","doi-asserted-by":"crossref","first-page":"1407","DOI":"10.1164\/ajrccm\/142.6_Pt_1.1407","article-title":"Identification of activated T lymphocytes and eosinophils in bronchial biopsies in stable atopic asthma","volume":"142","author":"Azzawi","year":"1990","journal-title":"Am Rev Respir Dis"},{"key":"10.1016\/j.anai.2016.08.008_bib17","doi-asserted-by":"crossref","first-page":"1570","DOI":"10.1016\/j.jaci.2012.03.023","article-title":"Comparative dietary therapy effectiveness in remission of pediatric eosinophilic esophagitis","volume":"129","author":"Henderson","year":"2012","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.anai.2016.08.008_bib18","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/j.cgh.2007.12.045","article-title":"Atopic characteristics of adult patients with eosinophilic esophagitis","volume":"6","author":"Roy-Ghanta","year":"2008","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.anai.2016.08.008_bib19","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1097\/MCG.0b013e3181a1bee5","article-title":"The role of allergy evaluation in adults with eosinophilic esophagitis","volume":"44","author":"Penfield","year":"2010","journal-title":"J\u00a0Clin Gastroenterol"},{"key":"10.1016\/j.anai.2016.08.008_bib20","first-page":"338","article-title":"Eosinophilic esophagitis due to profilin allergy","volume":"19","author":"Dominguez-Ortega","year":"2009","journal-title":"J\u00a0Investig Allergol Clin Immunol"},{"key":"10.1016\/j.anai.2016.08.008_bib21","doi-asserted-by":"crossref","first-page":"1090","DOI":"10.1016\/j.jaci.2005.01.017","article-title":"Eosinophilic esophagitis is frequently associated with IgE-mediated allergic airway diseases","volume":"115","author":"Simon","year":"2005","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.anai.2016.08.008_bib22","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1159\/000357006","article-title":"Eosinophilic esophagitis and allergy","volume":"32","author":"Simon","year":"2014","journal-title":"Dig Dis"},{"key":"10.1016\/j.anai.2016.08.008_bib23","doi-asserted-by":"crossref","first-page":"1292","DOI":"10.1016\/j.jaci.2007.10.024","article-title":"IL-13 involvement in eosinophilic esophagitis: transcriptome analysis and reversibility with glucocorticoids","volume":"120","author":"Blanchard","year":"2007","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.anai.2016.08.008_bib24","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.gtc.2014.02.006","article-title":"Allergic mechanisms in eosinophilic esophagitis","volume":"43","author":"Wechsler","year":"2014","journal-title":"Gastroenterol Clin North Am"},{"key":"10.1016\/j.anai.2016.08.008_bib25","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1067\/mai.2001.119917","article-title":"Idiopathic eosinophilic esophagitis is associated with a T(H)2-type allergic inflammatory response","volume":"108","author":"Straumann","year":"2001","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.anai.2016.08.008_bib26","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1016\/j.gastro.2003.07.007","article-title":"Intratracheal IL-13 induces eosinophilic esophagitis by an IL-5, eotaxin-1, and STAT6-dependent mechanism","volume":"125","author":"Mishra","year":"2003","journal-title":"Gastroenterology"},{"key":"10.1016\/j.anai.2016.08.008_bib27","doi-asserted-by":"crossref","first-page":"2464","DOI":"10.4049\/jimmunol.168.5.2464","article-title":"IL-5 promotes eosinophil trafficking to the esophagus","volume":"168","author":"Mishra","year":"2002","journal-title":"J\u00a0Immunol"},{"key":"10.1016\/j.anai.2016.08.008_bib28","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1038\/ajg.2008.169","article-title":"Seasonal distribution in newly diagnosed cases of eosinophilic esophagitis in adults","volume":"104","author":"Almansa","year":"2003","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.anai.2016.08.008_bib29","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1016\/S0091-6749(03)01715-9","article-title":"Pollen and eosinophilic esophagitis","volume":"112","author":"Fogg","year":"2003","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.anai.2016.08.008_bib30","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1111\/j.1365-2036.2009.04199.x","article-title":"Correlation between eosinophilic oesophagitis and aeroallergens","volume":"31","author":"Moawad","year":"2010","journal-title":"Alimentary Pharmacol Ther"},{"key":"10.1016\/j.anai.2016.08.008_bib31","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1172\/JCI10224","article-title":"An etiological role for aeroallergens and eosinophils in experimental esophagitis","volume":"107","author":"Mishra","year":"2001","journal-title":"J\u00a0Clin Invest"},{"key":"10.1016\/j.anai.2016.08.008_bib32","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1053\/j.gastro.2005.06.027","article-title":"Epicutaneous antigen exposure primes for experimental eosinophilic esophagitis in mice","volume":"129","author":"Akei","year":"2005","journal-title":"Gastroenterology"},{"key":"10.1016\/j.anai.2016.08.008_bib33","doi-asserted-by":"crossref","first-page":"1480","DOI":"10.1111\/j.1398-9995.2006.01224.x","article-title":"Eosinophilic esophagitis in adults: no clinical relevance of wheat and rye sensitizations","volume":"61","author":"Simon","year":"2006","journal-title":"Allergy"}],"container-title":["Annals of Allergy, Asthma & Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1081120616305312?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1081120616305312?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T13:15:35Z","timestamp":1761052535000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1081120616305312"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,10]]},"references-count":33,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2016,10]]}},"alternative-id":["S1081120616305312"],"URL":"https:\/\/doi.org\/10.1016\/j.anai.2016.08.008","relation":{},"ISSN":["1081-1206"],"issn-type":[{"value":"1081-1206","type":"print"}],"subject":[],"published":{"date-parts":[[2016,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Role of food and aeroallergen sensitization in eosinophilic esophagitis in adults","name":"articletitle","label":"Article Title"},{"value":"Annals of Allergy, Asthma & Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.anai.2016.08.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 American College of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}